Puma concolor (puma): 112854095
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Entry
112854095 CDS
T08890
Symbol
ERBB2
Name
(RefSeq) receptor tyrosine-protein kinase erbB-2
KO
K05083
receptor tyrosine-protein kinase erbB-2 [EC:
2.7.10.1
]
Organism
pcoo
Puma concolor (puma)
Pathway
pcoo01521
EGFR tyrosine kinase inhibitor resistance
pcoo01522
Endocrine resistance
pcoo01524
Platinum drug resistance
pcoo04010
MAPK signaling pathway
pcoo04012
ErbB signaling pathway
pcoo04020
Calcium signaling pathway
pcoo04066
HIF-1 signaling pathway
pcoo04151
PI3K-Akt signaling pathway
pcoo04510
Focal adhesion
pcoo04520
Adherens junction
pcoo04530
Tight junction
pcoo05200
Pathways in cancer
pcoo05205
Proteoglycans in cancer
pcoo05206
MicroRNAs in cancer
pcoo05212
Pancreatic cancer
pcoo05213
Endometrial cancer
pcoo05215
Prostate cancer
pcoo05219
Bladder cancer
pcoo05223
Non-small cell lung cancer
pcoo05224
Breast cancer
pcoo05226
Gastric cancer
pcoo05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
pcoo00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
112854095 (ERBB2)
04012 ErbB signaling pathway
112854095 (ERBB2)
04066 HIF-1 signaling pathway
112854095 (ERBB2)
04020 Calcium signaling pathway
112854095 (ERBB2)
04151 PI3K-Akt signaling pathway
112854095 (ERBB2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
112854095 (ERBB2)
04520 Adherens junction
112854095 (ERBB2)
04530 Tight junction
112854095 (ERBB2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
112854095 (ERBB2)
05206 MicroRNAs in cancer
112854095 (ERBB2)
05205 Proteoglycans in cancer
112854095 (ERBB2)
05230 Central carbon metabolism in cancer
112854095 (ERBB2)
09162 Cancer: specific types
05212 Pancreatic cancer
112854095 (ERBB2)
05226 Gastric cancer
112854095 (ERBB2)
05219 Bladder cancer
112854095 (ERBB2)
05215 Prostate cancer
112854095 (ERBB2)
05213 Endometrial cancer
112854095 (ERBB2)
05224 Breast cancer
112854095 (ERBB2)
05223 Non-small cell lung cancer
112854095 (ERBB2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
112854095 (ERBB2)
01524 Platinum drug resistance
112854095 (ERBB2)
01522 Endocrine resistance
112854095 (ERBB2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pcoo01001
]
112854095 (ERBB2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
pcoo04147
]
112854095 (ERBB2)
04090 CD molecules [BR:
pcoo04090
]
112854095 (ERBB2)
Enzymes [BR:
pcoo01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
112854095 (ERBB2)
Protein kinases [BR:
pcoo01001
]
Receptor tyrosine kinases (RTK)
EGFR family [OT]
112854095 (ERBB2)
Exosome [BR:
pcoo04147
]
Exosomal proteins
Exosomal proteins of breast cancer cells
112854095 (ERBB2)
CD molecules [BR:
pcoo04090
]
Proteins
112854095 (ERBB2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
GF_recep_IV
Pkinase
Furin-like
TM_ErbB1
ABC1
Haspin_kinase
Kinase-like
Motif
Other DBs
NCBI-GeneID:
112854095
NCBI-ProteinID:
XP_025773333
UniProt:
A0A6P6HCS3
LinkDB
All DBs
Position
Unknown
AA seq
1260 aa
AA seq
DB search
MELAAWCRWGLLLALLPSGATGTQVCTGTDMKLRLPASPETHLDMLRHLYQGCQVVQGNL
ELTYLHANASLSFLQDIQEVQGYVLIAHNQVRQVPLQRLRIVRGTQLFEDNYALAVLDNG
DPLDSGTPATGAALGGLRELQLRSLTEILKGGVLIQRNPQLCHQDTILWKDIFHKNNQLA
LMLIDTNRSRACQPCSPACKDSHCWGASSGDCQSLTRTVCAGGCARCKGPQPTDCCHEQC
AAGCTGPKHSDCLACLHFNHSGICELHCPALVTYNTDTFESMPNPEGRYTFGASCVTACP
YNYLSTDVGSCTLVCPLNNQEVTAEDGTQRCEKCSKPCARVCYGLGMEHLREARAVTSAN
IQEFVGCKKIFGSLAFLPESFEGDPASNTAPLQPEQLRVFEALEEITGYLYISAWPDSLP
NLSVFQNLRVIRGRVLHDGAYSLTLQGLGISWLGLRSLRELGSGLALIHRNSRLCFVHTV
PWDQLFRNPHQALLHSANRPEDECAGEGLACYPLCAHGHCWGPGPTQCVNCSQFLRGQEC
VEECRVLQGLPREYVKDRFCLPCHPECQPQNGSVTCLGSEADQCVACAHYKDPPFCVARC
PSGVKPDLSFMPIWKFADEEGTCQPCPINCTHSCADLDEKGCPAEQRASPVTSIIAAVVG
ILLVVVVGLVLGILIKRRRQKIRKYTMRRLLQETELVEPLTPSGAMPNQAQMRILKETEL
RKVKVLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSP
YVSRLLGICLTSTVQLVTQLMPYGCLLDHVREHRGRLGSQDLLNWCVQIAKGMSYLEDVR
LVHRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALESILRRRFT
HQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWM
IDSECRPRFRELVAEFSRMARDPQRFVVIQNEDLGPASPLDSTFYRSLLEDEDMGDLVDA
EEYLVPQQGFFCPDPAPGAGGTAHRRHRSSSTRSGGGELTLGLEPSEEEPPKSPLAPSEG
AGSDVFDGDLGMGAAKGLQSLSPQDPSPLQRYSEDPTVPLPPETDGYVAPLTCSPQPEYV
NQPEVWPKPPSPLEGPLPPSRPAGATLERPKTLSPKTLSPGKNGVVKDVFAFGGAVENPE
YLAPRGRAAPQPHPPPAFSPAFDNLYYWDQDTSERGSPPSTFEGTPTAENPEYLGLDVPV
NT seq
3783 nt
NT seq
+upstream
nt +downstream
nt
atggagctggcggcctggtgccgctgggggctcctcctcgccctcctgccctccggagcc
acgggcacccaagtgtgcaccggcacagacatgaagctgcggctcccagccagtcccgag
acccacctggacatgctccgccacctctaccagggctgtcaagtggtacagggcaacctg
gagctcacctacctgcatgccaatgccagcctctccttcctgcaggacatccaggaggtg
caaggctatgtgctcattgcccacaaccaagtgagacaggtcccactgcagaggctacga
atcgtgcgaggcacccagctctttgaggacaactacgccctggccgtgctggacaacgga
gacccactggacagtggcacccctgctacaggggctgccctaggagggctgcgggagctg
cagctccgaagcctcacagagatcctgaagggaggggtcctcattcagcggaacccgcag
ctctgccaccaggacacgattctgtggaaggacatcttccataagaacaaccagctggcc
ctcatgctgatagacaccaaccgctctcgggcctgccaaccctgttctccagcttgtaaa
gactcccactgctggggagcaagttccggggactgtcagagcttgactcgaactgtctgt
gctggtggctgtgcccgctgcaagggcccgcagcccactgactgctgccacgagcagtgt
gctgctggctgcacgggccccaagcattctgactgcctggcctgcctccacttcaaccac
agtggcatctgtgagctgcactgcccagccctggtcacctacaacacggacaccttcgaa
tccatgcccaaccctgagggccgttataccttcggtgccagctgtgtgactgcctgtccc
tacaactacctgtctacggacgtgggatcctgcaccctggtctgtcccctgaacaaccaa
gaggtgacagctgaggatggaacacagcggtgtgagaaatgcagcaagccctgtgcccga
gtgtgctacggcctaggcatggagcacctgcgggaggcgagggcagtcaccagtgccaac
atccaagaatttgtcggctgcaagaagatctttgggagcctggcgtttctgccagagagc
tttgagggggacccagcctccaacactgcccccctgcagcctgagcagctcagagtgttt
gaggctctggaggagattacaggttacctgtacatctccgcgtggccagacagcttgcct
aacctcagtgtcttccagaacctcagagtgatccggggccgagttctgcatgacggtgct
tactcgctgacccttcaagggctgggcatcagctggctggggctgcgctcgctgcgggag
ctgggcagtgggctggccctcatccaccgcaactcccgcctctgcttcgtacacacggtg
ccctgggaccagctcttccggaacccccaccaggccctgctccacagcgccaaccggcca
gaggacgagtgcgcgggtgagggcctggcctgctacccgctgtgtgcccatgggcactgc
tggggtccgggacccacccagtgtgtcaactgcagccagttccttcggggccaggagtgc
gtggaggaatgccgagtactgcaggggcttccccgggagtatgtgaaggataggttctgt
ctgccatgccacccggagtgtcagccccagaatggctcagtgacctgcttgggctcggaa
gctgaccagtgtgtggcctgtgcccactacaaggaccctcctttctgtgtggctcgctgc
cccagtggggtgaaacctgacctctccttcatgcccatctggaagttcgcagatgaggag
ggcacgtgccagccatgccccatcaactgcacccactcctgtgcggacctggacgagaag
ggctgccccgccgagcagagagccagccctgtgacgtccatcattgctgctgtggtgggc
attctgctggtcgtggttgtggggctggtccttggcatcctaatcaagcgaaggcggcag
aagatccggaagtacacgatgcggaggctgctgcaggagacggagctggtggagcccctg
acgcctagtggagccatgcccaaccaggctcagatgcgaatcctgaaagaaacagagctg
aggaaggtgaaggtgcttggatccggagcttttggcactgtctacaagggcatctggatc
cctgatggggaaaatgtgaaaatcccagtggccatcaaagtgttgagggaaaatacatct
cccaaagccaacaaagaaatcttggacgaagcgtatgtgatggctggcgtgggctcccca
tatgtgtctcgccttctgggcatctgtctgacatccaccgtgcagttggtgacacagctt
atgccttatggctgcctcttagaccatgtccgagaacaccgtgggcgcctaggctcccag
gacctgctgaactggtgtgtgcagattgccaaggggatgagctacttggaggatgttcgg
ctcgtgcacagggacctggctgcccggaacgtgctggtcaagagtcccaaccacgtcaag
attacagattttgggctggctcggctgctggacattgacgagacagagtaccatgccgac
gggggcaaggtgcccatcaagtggatggcgctggagtccattctccgccggcggttcacc
catcagagtgacgtgtggagctacggtgtgactgtatgggaactgatgacttttggggcc
aaaccttatgatgggatcccagcccgggagattcctgacctgctggagaagggggaacgg
ctgccccagccccccatctgcaccattgatgtctacatgatcatggtcaaatgttggatg
atagactctgaatgtcggccacgtttccgggagttggtggccgaattctcccggatggcc
agggacccccagcgctttgtggtcatccagaatgaggacttgggcccagccagtcccttg
gacagcactttctaccgttcactgctggaggatgaggacatgggagacctggtggacgct
gaggagtacctggtaccccagcagggtttcttctgcccagaccctgccccaggcgccggg
ggcacagcccaccgcagacaccgcagctcatccaccaggagtggcggtggtgagctgaca
ctggggctggagccctccgaggaagagcctcccaagtctccactggcaccctcagaaggg
gctggctctgatgtgtttgatggcgacttgggaatgggggcagccaaggggctgcagagc
ctttccccacaggaccccagccctctacagcggtacagtgaggatcctaccgtaccccta
ccccctgagactgatggctacgttgcccccctgacctgcagtccccagcctgaatacgtg
aaccagccagaggtttggccaaagcccccatcgcccttagaaggccctctgcctccttct
cgacctgccggtgccactctggaaaggcccaagactctgtcccccaagactctttccccc
ggcaagaatggggttgtcaaagacgtttttgcctttgggggtgctgtggagaaccccgag
tacttggcacccaggggcagggctgcccctcagccccaccctcctccagccttcagccca
gcctttgacaacctctattactgggaccaggacacatctgagcggggctctccacccagc
acctttgaagggacccctacagcagagaaccccgaatacctgggcctggatgtgccagtg
tga
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integrated database retrieval system
