| Entry |
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| Symbol |
ABCC2
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| Name |
(RefSeq) canalicular multispecific organic anion transporter 1
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| KO |
| K05666 | ATP-binding cassette, subfamily C (CFTR/MRP), member 2 |
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| Organism |
pcoo Puma concolor (puma)
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| Pathway |
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| Brite |
KEGG Orthology (KO) [BR:pcoo00001]
09130 Environmental Information Processing
09131 Membrane transport
02010 ABC transporters
112854434 (ABCC2)
09150 Organismal Systems
09154 Digestive system
04976 Bile secretion
112854434 (ABCC2)
04981 Folate transport and metabolism
112854434 (ABCC2)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
112854434 (ABCC2)
01523 Antifolate resistance
112854434 (ABCC2)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:pcoo02000]
112854434 (ABCC2)
Transporters [BR:pcoo02000]
ABC transporters, eukaryotic type
ABCC (CFTR/MRP) subfamily
ABCC1, 2, 3, 4, 5, 6, 10, 11, 12, 13 subgroups
112854434 (ABCC2)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
Unknown
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| AA seq |
1542 aa
MLEKFCNSTFWNSSFLDSPEADLPLCFEQTVLVWIPLGFLWLLAPWQLLHVYRTKINRSS
ITKLYLAKQVLVGFLLILAAIELALVLTEDSGQATVPAIRYTNPSLYLGTWLLVLLFQHS
RLWCVQKDSWFLSLFWILSVLCGVFQFQTLIRTLLKGNNSNLAYSCLFFICYALNVLILI
LSAFSEKDDSSNIPSFTASFLSSITFSWYNSIVLKGYKQPLTLEDVWDLDEKIKTKTLVS
KFEKRMAGELQKARKAVQRRQRGRAQGNSRDRLHGLNKNQSQSQDILVLEDVKKKEKSGT
TENFPKAWLVKTLFKTFYVILLKSFLLKLMHDLLLFLNPQLLKLLISFANNRDAYVWVGY
LYSVLFFVVALIQSLCLQNYFQLCFMLGTSVRATVMASVYKKALTLSNQSRKQYTIGETV
NLMSVDAQKLMDVTSFIHLLWSNILQITLCISFLWAELGPSVLAGVGVMVLLIPINGILA
TKSRAVQVKNMKNKDKRLKIMNEILSGIKILKYFAWEPSFKKQVHELRKKELKNLLTLGQ
MQTIMTFLLYISPVLVSVITFSVYILVNSNNVLDAEKAFTSITLFNILRFPLSMFPMVIT
SMLQASVSTERLEKYLGGDELDTSAIRHEYNFEKAVQFSEASFTWDRDLEATIRDVNLDI
MPGQLVAVVGTVGSGKSSLMSAMLGEMENVHGHITIKGTIAYVPQQSWIQNGTLKDNILF
GSELDEKKYQQVLEACALLPDLEVLPGGDLAEIGEKGINLSGGQKQRISLARATYQNSDI
YVLDDPLSAVDAHVGKHIFNKVLGPNGLLKGKTRLLITHSIHFLPQVDEIVVLGNGTILE
KGSYSTLLAKKGLFAKILKTSKKQMGLEGEATVNEDSEEDDCGLMPSVEEIPEEVASLTM
RRENSLHRTLSHSSRSSSRHRKSLKNSLKTRNVNTLKEEEELVKGQKLIKKEFIQTGKVK
LSIYLKYLRAMGLCLIFFIILAYVINAVAYIGSNLWLSAWTNDSKTYNGTNYPASQRDLR
AGVYGALGLVQGVFVLLGNLCSIRASTHASNILHKQLLTNILRAPMSFFDTTPTGRIVNR
FAGDISTVDDTLPLSLRSWILCFLGIISTLVMICMATPIFITVIIPLGIIYTFVQMFYVA
TSRQLKRLDSVTRSPIYSHFSETVSGLSVIRAFEHQQRFLKHNEVGIDTNQKCVFSWIVS
NRWLAVRLELIGNLIVFFASMMMVIYRDTLSGDTAGFVLSNALNITQTLNWLVRMTSEVE
TNIVAVERINEYTKVENEAPWVTDKRPPPGWPSKGEIQFNNYQLRYRPELDLILKGITCD
IKSMEKVGVVGRTGAGKSSLTNALFRILEAAGGQIIIDGVDIASIGLHDLREKLTIIPQD
PILFSGSLRMNLDPFNNHSDEEIWKALELAHLKSFVAGLQLGLSHKVTEAGDNLSIGQRQ
LLCLARALLRKSKILIMDEATAAVDIETDHLIQTTIQKEFSHCTTITIAHRLHTIMDSDK
IMVLDNGKIVEYGTPNELLKNSGPFCLMAKEAGIENVNSTSL |
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| NT seq |
4629 nt +upstreamnt +downstreamnt
atgctggagaagttctgcaactctacattttggaattcttcattcctggatagcccagaa
gcagacctgccactttgttttgagcaaactgttctggtgtggattcccttgggtttcctt
tggctcctggccccttggcagcttcttcatgtatacagaaccaagatcaacagatcatct
atcaccaaactctatcttgctaagcaggtgcttgttgggttccttcttattctagcagcc
atagaactggcccttgtactcacagaagactctggacaagccacggtccctgccattaga
tataccaatccaagcctttacctgggcacatggctcctggttttgctgttccaacacagc
agactatggtgtgtgcagaaggactcttggttcctgtccctattctggattctctcagta
ctctgtggcgtcttccagtttcagactctgatccggacactcttaaagggcaacaattct
aatctggcttactcctgcctgttcttcatctgctatgcgctgaacgtcctgatcctgata
ctttcagcattttcagaaaaagatgactcctcaaatattccatcattcacggcttcattt
ctgagtagcattacctttagttggtataacagcattgttctgaaaggctacaagcaacct
ctgacactcgaagatgtctgggatcttgatgaaaagattaaaacgaagaccctggtcagc
aagtttgaaaaacgtatggcaggagagctgcagaaggccaggaaggcagtccagagacga
cagcgggggagagcacaggggaactccagggacaggctgcatggcttgaacaagaatcag
agtcaaagccaagatatccttgtcctggaagatgttaaaaagaaagaaaagtctggcact
acagaaaactttcccaaggcctggttggtcaagactctcttcaaaactttctacgtcata
ctcttgaagtccttcctactgaagctgatgcatgacctcctcctgtttctgaatcctcag
ctgctgaaattgctgatctcctttgcaaataaccgagatgcgtatgtgtgggttggatat
ctctattcggtcctcttctttgttgtggccctcatccagtctctctgccttcagaattac
tttcaactgtgcttcatgctggggacaagtgtgcgggcaaccgtcatggcttccgtatat
aagaaggcgctgaccctatccaaccagagcagaaagcagtacaccattggagaaactgtg
aacctgatgtctgtggatgcccagaagctcatggatgtgaccagcttcatccatttgctg
tggtcaaatattctacagattactttatgtatctccttcctatgggcagagctgggaccc
tcagtcttagcaggtgttggggtgatggtacttctaatcccaattaatgggatacttgcc
accaagagtagagctgttcaggtaaaaaatatgaagaataaagacaaacgtttaaagatc
atgaatgaaattctcagtgggatcaagatcctgaagtattttgcctgggaaccttcattc
aaaaagcaagtccatgaacttcggaagaaagagctcaagaacctgctgaccttgggtcag
atgcagactataatgacatttctcttatacataagtccagtcctggtgtctgtgatcaca
ttttcagtttacattctggtgaatagcaataatgttttggatgcagaaaaggccttcacc
tccatcaccctcttcaatatcctgcgtttccccctgagtatgtttcccatggtaatcacc
tccatgttacaggccagcgtttccacagaacggctagaaaagtacttgggaggggatgag
ttggacacatccgccattcgacatgagtacaattttgaaaaagctgtgcagttttcagag
gcctcctttacctgggaccgggatctggaagccacaattcgagatgtgaacctggacatt
atgccaggccaattggtggctgtggtgggcactgtgggctctgggaagtcttccttgatg
tcagccatgctgggagaaatggaaaatgtccacgggcacatcaccatcaagggcactata
gcctatgtcccacagcaatcctggatccagaatggcaccttaaaggacaacatccttttt
ggatccgagttggatgaaaagaaataccagcaggttctggaggcctgtgccctcctccca
gacttggaagtgctgcccggaggagacctggccgagattggagagaagggtataaatctc
agtgggggtcagaagcagcggattagcctggccagagctacctatcaaaattcagacatc
tatgttctggatgaccccctgtcagctgtggatgctcatgtgggaaaacatattttcaat
aaggtcttgggtcccaatggcctattgaaaggcaagactcgactcttgattacacatagc
attcactttcttccccaagtggatgagattgtggtgctggggaatggcaccatcctggag
aagggatcctacagcactctgctggccaagaaaggattgtttgctaagattctgaagaca
tccaaaaaacagatgggtcttgaaggagaggccacagtcaatgaggacagtgaagaagat
gattgtgggctgatgcccagtgtggaggaaatccctgaggaggtggcctccttgaccatg
agaagagagaacagccttcatcgaacacttagtcacagttctaggtccagtagcaggcac
cggaaatccctaaaaaactctttgaaaactcggaatgtgaataccctgaaggaggaggaa
gaactagtcaaaggacaaaaactaattaagaaggaattcatacaaactggaaaggtgaag
ctgtccatctacctgaaatacctgcgagccatgggattgtgtttgatattcttcatcatc
cttgcctatgtgatcaatgctgtggcttatattggatccaacctctggctcagcgcttgg
accaatgactctaaaacctataatggcactaactatccagcctcacagagggacctgaga
gctggcgtctatggagctctgggattggtacaaggtgtgtttgtgctcctaggaaatctt
tgcagtatccgtgcttccactcatgcgtcaaacatccttcacaagcaactgctaaccaat
atccttcgagcacccatgagtttttttgacacaacacccacaggccggattgtgaacagg
ttcgctggtgatatctccacggtggatgacaccctccccttgtccctgcgaagctggata
ctgtgcttcctgggaatcatcagcacccttgtcatgatctgcatggccactcccatcttt
atcaccgtcatcattccccttggcatcatttatacatttgtgcagatgttttatgtggct
acttcccgccagctgaaacgtctggactctgtcaccaggtccccaatctactctcacttc
agtgagactgtgtcaggtttgtctgtcatccgtgcctttgagcatcagcagcgatttcta
aaacataatgaggtggggattgacaccaaccagaaatgtgtcttctcttggattgtctcc
aacaggtggcttgcagtccgtctggagctgattgggaacctgattgtcttctttgcatct
atgatgatggttatttatagagatacactaagtggagacactgcgggctttgttctgtcc
aatgcacttaatatcacacaaaccctgaactggttagtgaggatgacgtcagaagtagag
accaacattgtggctgttgaacgaataaatgagtacaccaaagtggaaaacgaggcaccc
tgggtgactgataagagacctcccccaggttggcccagcaaaggggagatccagtttaac
aactaccaactacggtaccggcctgagctggatctcatactgaaagggatcacctgtgac
attaagagtatggagaaggttggtgtggtcggcaggacaggagctgggaagtcatccttg
acaaatgccctcttcagaatcctagaggctgcaggtggccagatcatcattgatggggta
gatattgcttccattgggctccatgacctccgagagaaactgaccatcatcccccaggat
cccatcctgttctccggaagcctgaggatgaatctagatccttttaacaaccactcagat
gaggagatttggaaggccctggagctggctcacctcaaatcctttgtggctggcctgcaa
cttggattgtcccacaaagtgacagaggctggtgacaaccttagcatagggcagaggcag
ctgctgtgcctggccagggctctgcttcggaaatccaagattctgatcatggatgaggcc
actgctgcggtggatatagagaccgatcaccttatccagacgaccatccaaaaggagttc
tcccactgcacgactatcaccattgctcataggctccacaccatcatggacagtgacaag
ataatggtcctagacaacgggaagattgtagagtatggcacccctaacgaactgctgaaa
aattctggccccttttgtttgatggccaaagaagctggcattgaaaatgtgaacagcaca
tcactctga |
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