Puma concolor (puma): 112855015 Help Entry 112855015         CDS       T08890                                  Symbol PLA2G4B Name (RefSeq) cytosolic phospholipase A2 beta   KO K16342   cytosolic phospholipase A2 [EC:3.1.1.4] Organism pcoo  Puma concolor (puma) Pathway pcoo00564   Glycerophospholipid metabolism pcoo00565   Ether lipid metabolism pcoo00590   Arachidonic acid metabolism pcoo00591   Linoleic acid metabolism pcoo00592   alpha-Linolenic acid metabolism pcoo01100   Metabolic pathways pcoo04010   MAPK signaling pathway pcoo04014   Ras signaling pathway pcoo04072   Phospholipase D signaling pathway pcoo04217   Necroptosis pcoo04270   Vascular smooth muscle contraction pcoo04370   VEGF signaling pathway pcoo04611   Platelet activation pcoo04664   Fc epsilon RI signaling pathway pcoo04666   Fc gamma R-mediated phagocytosis pcoo04724   Glutamatergic synapse pcoo04726   Serotonergic synapse pcoo04730   Long-term depression pcoo04750   Inflammatory mediator regulation of TRP channels pcoo04912   GnRH signaling pathway pcoo04913   Ovarian steroidogenesis pcoo04921   Oxytocin signaling pathway pcoo05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:pcoo00001]  09100 Metabolism   09103 Lipid metabolism    00564 Glycerophospholipid metabolism     112855015 (PLA2G4B)    00565 Ether lipid metabolism     112855015 (PLA2G4B)    00590 Arachidonic acid metabolism     112855015 (PLA2G4B)    00591 Linoleic acid metabolism     112855015 (PLA2G4B)    00592 alpha-Linolenic acid metabolism     112855015 (PLA2G4B)  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     112855015 (PLA2G4B)    04014 Ras signaling pathway     112855015 (PLA2G4B)    04370 VEGF signaling pathway     112855015 (PLA2G4B)    04072 Phospholipase D signaling pathway     112855015 (PLA2G4B)  09140 Cellular Processes   09143 Cell growth and death    04217 Necroptosis     112855015 (PLA2G4B)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     112855015 (PLA2G4B)    04664 Fc epsilon RI signaling pathway     112855015 (PLA2G4B)    04666 Fc gamma R-mediated phagocytosis     112855015 (PLA2G4B)   09152 Endocrine system    04912 GnRH signaling pathway     112855015 (PLA2G4B)    04913 Ovarian steroidogenesis     112855015 (PLA2G4B)    04921 Oxytocin signaling pathway     112855015 (PLA2G4B)   09153 Circulatory system    04270 Vascular smooth muscle contraction     112855015 (PLA2G4B)   09156 Nervous system    04724 Glutamatergic synapse     112855015 (PLA2G4B)    04726 Serotonergic synapse     112855015 (PLA2G4B)    04730 Long-term depression     112855015 (PLA2G4B)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     112855015 (PLA2G4B)  09160 Human Diseases   09161 Cancer: overview    05231 Choline metabolism in cancer     112855015 (PLA2G4B) Enzymes [BR:pcoo01000]  3. Hydrolases   3.1  Acting on ester bonds    3.1.1  Carboxylic-ester hydrolases     3.1.1.4  phospholipase A2      112855015 (PLA2G4B) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PLA2_B cPLA2_C2 C2 Motif Other DBs NCBI-GeneID:  112855015 NCBI-ProteinID:  XP_025774362 UniProt:  A0A6P6HF66 LinkDB All DBs Position Unknown AA seq 781 aa AA seqDB search MALAKVPGTCLLTIRVLQACGLPSKDLVTPSDCYVSLWLPTASSHRLQTRTVKNSRNPIW NQSFRFRIHSQLKNVVQLQVFDQDLLTNDDPVLSVLFDVGTLRAGEFRRESFSLSAQGEE RLEVEFRLQRLTDCAEQLVTNGILVARELSCLHVRLEEAGDRKESGGRVQLMVPGSCEGP QEAAVGAGSFCFHCPACWEQELDIHLQDTPQEHLKVPLRALPSGQVVRLVFPTSQEPLMR VELRKEDGPRELAVRLGCGPCAEEQAFLSKRKQVVAKALKQVLQLDEDLQEDEIPVVAVM ATGGGIRAMVSLYGHLAGLKELGLLDCISYITGASGSTWALANLYEDPEWSQKDLAGPTE SLKTQVTKSKLGVLAPSQLQQYRQELAERARLGHPPCFTNLWALISEALLHDEPHDHTLS DQREALSQGQNPLPIYCALNTKEKNLTTFEFAEWCEFSPYEVGFPKYGAFIPSELFGSEF FMGCLTKRLPESRICFLKGIWSNLYAASLQDSLYWASEPSQFWDRWAQDQANLDKEQVPL LKIEEPPTGTGKIVEFFTDLLTRRPLAQATHNFLRGLQFHKDYFQQPYFSTWKATKLDGH PNQLTPAEPHLCLLDVGYLINTSFPPLLRPTRDVDLILSLDYNLQGAFQQLQLLGRLCQE QGIPFPPISPSPEEQRQPPECCLFSDPDRPDAPAVLHFPLVDASFREYSAPGIQRTPEEK GAGEVNLSSSNSPYHYSKLTYSPEDMDKLLHLTHYNICNNQEQLLEALRGAVQRKRRQHR P NT seq 2346 nt NT seq  +upstreamnt  +downstreamnt atggctctggcaaaggtgcctgggacctgcctgctcaccattcgtgtcttgcaggcctgt ggcctgccctcgaaggacctagtaaccccctctgactgctatgtgagtctgtggctgccc acggcctctagccataggctgcagacacgcacggtcaagaacagcagaaaccccatctgg aatcagagctttcgctttcgaatccacagccagctcaagaatgtggtgcagctgcaagtc tttgaccaggaccttctgaccaatgatgaccccgtgttgtcggtgctatttgacgtgggg actttgcgagctggggagttccgcagagagagcttctcactgagcgctcagggtgaggag cggctagaagttgaatttcggctacagagactgacagactgtgctgagcagcttgtcacc aatggcattctggtggcccgggagctctcttgcttgcatgttcgactggaggaggcaggg gaccggaaggagtccgggggaagagttcagctcatggttcctgggtcctgtgagggtccg caggaggccgctgtgggtgctggctccttctgcttccattgcccggcctgctgggagcag gagctggatattcatctgcaggataccccccaagagcacctgaaggtgcccctgagggcc ttgccctctgggcaggtggtgaggcttgtcttccctacgtcccaggaacccctgatgagg gtggagctgagaaaagaagacggacccagggagctggctgtgcggctaggctgcgggccc tgtgccgaggagcaggcctttctgagcaagaggaagcaggtggtggccaaggccctgaag caggtcctgcaactggatgaagacttacaggaagatgagatccccgtggtagctgttatg gccactggtggtgggatccgggcgatggtttccctgtatgggcatctggctggcctgaag gagctgggtctcttggattgcatctcctacatcacaggggcctctggctctacctgggct ttggccaacctctacgaggacccagaatggtctcagaaggacctggcagggcccaccgag tcactgaaaacacaggtgaccaagagcaagttgggcgtgcttgctcccagccagctgcag cagtaccggcaggagctggccgagcgtgcccgcctgggccacccgccctgcttcaccaac ctgtgggccctcattagtgaggccctgctgcacgatgagccccatgaccatactctctca gaccagagagaggccctgagtcaaggccagaaccctctgcccatttactgtgcccttaac accaaggagaagaacctgaccacctttgaatttgctgagtggtgtgagttctccccctat gaggttggctttcccaagtacggtgccttcatcccctccgagctctttggctctgagttc ttcatggggtgcctgaccaagcggcttcctgagtcccgaatctgcttcctgaaaggtatc tggagcaatctgtatgcagccagcctccaggacagcttatactgggcctcagagcccagc cagttctgggaccgctgggcacaggatcaggccaatttggacaaggagcaggttcctctc ctgaagatagaagagcctcccacggggaccggcaagattgttgagttttttactgacctt ctgacacggcgcccactggcccaggccacacataatttcctgcgtggtcttcagttccac aaagactatttccaacagccttacttctccacctggaaagccaccaaactggatgggcac cccaaccagctgacacctgcagagccccatctttgcctgctggatgttggctaccttatc aacaccagtttcccaccccttctgcggcccacacgggatgtggacctcatcctgtcactg gattacaacctccaaggagcctttcagcaactgcagctcctgggccggctctgtcaggag cagggcatccctttcccgcccatctcccccagcccagaggagcagcgccagcctccggag tgctgcttgttttctgatccagaccgccctgatgccccagcggtgctgcacttccctctg gtggatgcctccttccgggagtactcggcccctggcatccaacggacacctgaggagaag ggggccggagaggtgaacctgtcttcatccaactctccctaccactactcgaaattgacc tacagcccagaggacatggacaagctgctccacctgacacattacaacatctgcaacaac caggagcagctgctggaggccctgcgtggagctgtgcaacggaagcgccggcagcaccgg ccgtag

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