Puma concolor (puma): 112855084
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Entry
112855084 CDS
T08890
Symbol
POLE
Name
(RefSeq) DNA polymerase epsilon catalytic subunit A
KO
K02324
DNA polymerase epsilon subunit 1 [EC:
2.7.7.7
]
Organism
pcoo
Puma concolor (puma)
Pathway
pcoo03030
DNA replication
pcoo03410
Base excision repair
pcoo03420
Nucleotide excision repair
Brite
KEGG Orthology (KO) [BR:
pcoo00001
]
09120 Genetic Information Processing
09124 Replication and repair
03030 DNA replication
112855084 (POLE)
03410 Base excision repair
112855084 (POLE)
03420 Nucleotide excision repair
112855084 (POLE)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
pcoo03032
]
112855084 (POLE)
03400 DNA repair and recombination proteins [BR:
pcoo03400
]
112855084 (POLE)
Enzymes [BR:
pcoo01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.7 Nucleotidyltransferases
2.7.7.7 DNA-directed DNA polymerase
112855084 (POLE)
DNA replication proteins [BR:
pcoo03032
]
Eukaryotic type
DNA Replication Elongation Factors
DNA polymerase epsilon complex
112855084 (POLE)
DNA repair and recombination proteins [BR:
pcoo03400
]
Eukaryotic type
SSBR (single strand breaks repair)
BER (base exicision repair)
Long Patch-BER factors
DNA polymerase epsilon complex
112855084 (POLE)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
DUF1744
POL2_thumb
DNA_pol_B_exo1
zf_DPOE_2
zf-DPOE
DNA_pol_B_exo2
RNase_H_2
DNA_pol_B
APP_N
Sigma70_ner
Motif
Other DBs
NCBI-GeneID:
112855084
NCBI-ProteinID:
XP_025774419
UniProt:
A0A6P6HF63
LinkDB
All DBs
Position
Unknown
AA seq
1970 aa
AA seq
DB search
MDEEEGGAEAAVATKGQQEGSAHWYNVRYRGNAFPVEITRRDDLVERPDPVVLAFDIETT
KLPLKFPDAETDQIMMISYMIDGQGYLITNREIVSEDVGDFEFTPKPEYEGPFCVFNEPD
EVHLIQRWFEHVQEAKPTIMVTYNGDFFDWPFVEARAAVHGLSMYQEIGFQKDSQGEYKA
SQCIHMDCLRWVKRDSYLPVGSHNLKAAAKAKLGYDPVELDPEDMCRMATEQPQTLATYS
VSDAVATYYLYMKYVHPFIFALCTIIPMEPDEVLRKGSGTLCEALLMVQAFHANIVFPNK
QEQEFNKLTSDGHVLDAETYVGGHVEALESGVFRSDIPCRFRMNPAAFDFLLQRVEKTMR
HAIEEEEKVPMEQVTNFQEVCDQIKTKLTSLKDVPNRIECPLIYHLDVGAMYPNIILTNR
LQPSAVVDEATCAACDFNKPGADCQRKMAWQWRGEFMPASRSEYHRIQHQLESEKFPPLT
AEGPARAFHELSREEQAKYEKRRLSDYCRKAYKKIHVTRVEERLTTICQRENSFYVDTVR
AFRDRRYEFKGLHKTLGCFRGLATVKNAAVNVGVKLPPLPLVMQEGFTNDQYQELTEPAS
LTYVTRSENSIFFEVDGPYLAMILPASKEEGKKLKKRYAVFNEDGSLAELKGFEIKRRGE
LQLIKIFQSSVFEAFLKGSTLEEVYGSVAKVADYWLDVLYSKAANMPDSELFELISENRS
MSRKLEDYGEQKSTSISTAKRLAEFLGDQMVKDAGLSCRYIISRKPEGSPVTERAIPLAI
FQAEPMVRKHFLRKWLKSSSLQDFDIRTILDWDYYIERLGSAIQKIITIPAALQQVKNPV
PRVKHPDWLHKKLLEKNDICKQKKISELFVLEGRRQVGVAQAPEGTQSLGAPDMEDLGLA
KPPRSVVPVATRRKRVLWESQGESQDLELTVPWQEILGPPPALGTTQEEWLVWLRFHKKK
WQLQARQRLGRKKRRRLEVAEGDPRPGAVRDRPATGLGGFLQRAARSILDLPWQIVQISE
TSQAGLFRLWAVISSDLYCIRLNIPRQFYVNQRVAKAEEGPSYRKVSRVLPRSNVVYNLY
EYSVPEDMYQEHVNEINTELSAPDIEGVYETQVPLLFRALVQLGCVCVVNKQLVRHLSGR
EAETFALEHLEMRSLAQFSYLEPGSIRHLYLYHHAQGHKALFGLFVPSQRRASVFVLDTV
RSNQMPSLSALYTAEHSLLMEKVGPELLPPPKHTFEVRAETDLKTICRAIQRFLLAYKEE
RRGPTLIAVQSNWELKRLAGEVPILEDFPLVPVRVADRVSYGVLDWQRLGARRMIRHYLN
LDTCLSQAFEMSRYFHIPIGNLPEDISTFGSDLFFARHLQRHNHLLWLSPTARPDLGGKE
ADDNRLVMEFDDQASVEINCPGCYSTLCVELDIQNLAVNTILQSHHINDMEGADSVGISF
DVIQQASLEDMITGNQAAGTPASYDETALCSSTFRILKSMVVGWVKEITQYRNIYADNQV
MHFYRWLRSPSSLLHDPALHRTLHNMMKKLFLQLIAEFKRLGSSVVYANFNRIILCTKKR
RVADAIAYVEYITNSVHSKEIFHSLTISFSRCWEFLLWMDPSNYGGIKGNVPSSIHCGQQ
DSRKEGREEEEEEEEEEGGEEEEEEEEEEGAQEPDVEDMLENNWNIVQFLPQAASCQSYF
LMIVSAYIVAVYHSMKEELRRSVPGSTPLRRRGPSQLSQEAQAVAGALPGVITFSQDYVA
NELTQNFFTITQKIQKKVTGSRNATELSKMFPVLPGSHLLLNNPALEFIKYVCKVLSLDT
NITNQVNKLNRDLLRLVDVGEFSEEAQFRDPCRSYVLPEVICRSCNFCRDLDLCKEPSFS
QDGAVLPQWLCSNCLVAYDSSVIEMALVEAVQKKLMAFTLQDLICLKCRGVKETNMPVYC
SCAGDFALTIRTKVFMDQIRIFQNIAQHYGMSYLMETLEWLLQKNLQLGH
NT seq
5913 nt
NT seq
+upstream
nt +downstream
nt
atggatgaggaagagggaggagcggaggcggctgtggccacaaaagggcagcaggaggga
tccgctcactggtacaacgtcaggtaccgaggaaatgccttccctgtggaaatcacccgc
cgagatgaccttgttgaacgacccgaccctgtggttttggcatttgacatcgagacaacc
aaactgcccctcaagtttccagatgctgagactgaccagattatgatgatttcctatatg
attgacggtcagggctacctcatcaccaatagggagatagtgtcagaggacgttggagat
ttcgagttcacccccaagccagagtatgagggacccttctgtgtcttcaatgaacccgac
gaggttcatctaatccagaggtggtttgaacacgtccaagaggccaaacccaccatcatg
gtcacctacaatggggacttttttgactggccgtttgtggaggccagagcggcggtccat
gggctgagcatgtaccaggagatagggttccagaaggacagccagggggagtataaggca
tcccagtgcatccacatggactgtctcaggtgggtgaagagggacagttaccttcctgtg
ggcagtcacaacctcaaggcggctgccaaagccaagttgggctacgaccccgtggagctg
gaccctgaagacatgtgccggatggccaccgagcagccccagactctggccacatactcg
gtgtcagacgcggtggccacgtactacctgtacatgaagtacgtccaccccttcatattc
gccctctgcaccatcatccccatggagcctgacgaggtgctgcggaagggctccgggacg
ctgtgtgaggccttgttgatggtgcaggccttccatgccaacatcgtcttccccaacaag
caggagcaggagtttaacaagctgaccagtgatggccacgtgctggatgccgagacctat
gtgggtggccacgtggaggccctggagtcgggcgtgttccgcagtgacatcccctgccgg
ttcaggatgaatcctgccgcctttgacttcctgctgcagcgggtggagaagaccatgcgt
catgccatcgaggaagaggagaaggtgcccatggagcaggtcaccaacttccaagaggtg
tgtgatcagattaagaccaagctcacctccctgaaagatgtcccaaacagaatcgagtgt
ccccttatctaccacctggatgtgggggccatgtaccccaacatcatcctgacgaaccgc
ctgcagccctctgccgtggtggacgaggccacctgtgctgcctgtgacttcaacaagcct
ggagcagactgccagaggaagatggcctggcagtggaggggcgagttcatgccagccagt
cgcagcgagtaccatcggatccagcaccagctggagtcagagaagttccctcccttgact
gcagagggcccagcccgggcctttcacgagctgtcccgcgaggagcaggctaaatatgag
aagcggaggctgtcagattactgccggaaggcctacaagaagatccacgtgaccagggtg
gaggagcgcctcaccaccatctgccagcgggagaactccttctatgtggacacggtgcgc
gccttccgggacaggcgctatgagttcaagggtctccacaagacactgggttgcttccgc
ggtttggccactgtgaagaatgccgctgtgaacgtgggagtgaagctgcctccacttcct
cttgttatgcaggaaggcttcaccaatgatcagtaccaggagctgactgagccagcctca
ctcacctatgtcacccgctcagagaacagcatcttttttgaggttgatggaccctacctt
gccatgatccttccagcctccaaggaagagggcaagaaactgaagaagagatatgctgtc
ttcaacgaggacggttccctggctgagctaaagggcttcgagatcaaacgccggggggag
ctgcagctgattaaaatcttccagtcctcagtgtttgaggccttcctcaagggcagcacc
ctagaagaagtgtatggctccgtcgccaaggtggctgactactggctggacgtgctgtac
agtaaggccgcgaacatgcctgattctgagctgtttgagctgatctctgagaaccgctcc
atgtctcggaagctggaagattatggggagcagaagtccacgtctatcagcacggccaaa
cgcctggctgagttcctgggggatcagatggtgaaggacgcggggctgagctgccgctac
atcatctcccggaagcccgagggctctccagtcacagagagggccatcccactcgccatt
ttccaggcagagcccatggtgaggaagcattttctccggaaatggcttaagagttcttcc
ctccaagacttcgatattcggacaatcctggactgggactactacattgagcggctaggc
agtgccatacagaagatcatcacaatccctgcggccctgcagcaggtgaagaacccggtg
ccacgcgtcaagcaccctgactggctgcacaagaaacttctggagaagaatgacatctgc
aagcagaagaagatcagtgagctttttgtcctcgaaggccggagacaggtgggcgtggcc
caggctccagaaggcacacagagccttggtgctccggacatggaagacctcggcctggca
aagccaccgcgctcagtggttcctgttgccaccaggaggaagcgcgtcctctgggagagc
cagggggagtcgcaggacctggagctgacggtgccctggcaggagatcttggggccgcct
ccggccctcgggaccacgcaggaagagtggctggtctggctccgattccacaagaagaag
tggcagctgcaggcccggcagcgcctgggtcgcaagaagaggcggcgtctggaggtggca
gagggtgaccctcggcctggggctgtccgcgacaggcctgccaccgggctggggggcttc
ttgcaaagagccgcccgcagcattttggaccttccgtggcagattgtgcagatcagtgag
accagccaggccggcttgttcaggctgtgggccgtcatcagcagtgacttgtactgcatc
aggctgaacatcccccgccagttctatgttaaccagcgggtggctaaagccgaggagggg
ccttcataccgcaaggtcagtcgagtgcttcctcgctccaacgtggtctacaacctctac
gagtactcggtgcccgaggacatgtatcaggaacacgtcaacgagatcaatactgaattg
tcggccccagacatcgagggcgtgtacgagacacaggttccgttattgttccgggccctg
gtgcagctgggctgtgtgtgtgtggtcaataaacagctggtgagacacctttcaggccga
gaagcagaaacctttgctctcgagcacttggagatgcgctctctggcccagttcagctac
ttggaaccagggagcatccgccacctctacctgtaccaccacgcgcaaggccacaaggcg
ctctttggcctgtttgtgccctcccagcgcagggcgtctgtgttcgtgctggacaccgtg
cgaagcaaccagatgcccagcctcagcgccctgtacaccgccgagcacagcctcctgatg
gagaaggtgggccccgagctcctgcctccccccaaacacacttttgaagttcgggctgaa
accgacttgaaaaccatctgcagagccatccagcgcttcctgctggcctacaaggaggag
cgccgtgggcccacactcatcgctgttcagtccaactgggagctgaagaggctggctggc
gaggtgcccatcctggaggacttcccgctggtgccggtccgcgtggctgatagggtcagc
tatggagtcctggactggcagcgcctcggtgcccggcgcatgatccgccactacctcaac
ctggacacctgcctgtcccaggccttcgagatgagcaggtacttccacatccccattggg
aacctgcccgaagacatctccaccttcggctccgacctcttctttgcccgccacctgcag
cgccacaaccacctgctctggctgtcccccacggcgcgccctgacctgggcggcaaggag
gccgacgacaatcgcctcgtcatggagttcgacgaccaggccagcgtggagatcaactgt
ccgggctgctactccacgctgtgcgtggagctggacatccagaacctggccgtcaacacc
atcttgcagtcccaccacatcaatgacatggagggggctgacagcgtgggcatcagcttc
gacgtgatccagcaggcctccctggaggacatgatcaccggcaatcaggccgccggcacc
ccggccagctacgatgagacagccctctgctccagcacgttcaggatcctgaagagcatg
gtggtgggctgggtgaaggagatcacacagtaccgcaatatctacgctgacaaccaggtg
atgcacttctaccgctggctccggtccccatcctcgctgctgcacgaccccgccctgcac
cgcacgctccacaacatgatgaagaagctcttcctgcagctcatcgctgagttcaagcgc
ttggggtcctctgtcgtctatgccaacttcaaccgcatcatcctctgcacgaagaagcgg
cgggtcgcagacgccattgcctacgtggagtacatcaccaacagcgtccattctaaagag
atcttccattccttgacgatttctttctctcggtgctgggagtttcttctctggatggat
ccctctaactatggtggaatcaaaggaaacgtcccatctagtattcactgtggacagcaa
gactcccgaaaagaaggcagagaagaggaggaggaggaggaggaggaggaaggtggggag
gaggaggaggaggaggaggaggaggaaggtgcccaggagcccgacgtggaggacatgcta
gaaaacaactggaacatcgtgcagttcctgccacaggcagcctcctgccagagctacttc
ctcatgatcgtttcggcatacattgtggccgtgtatcacagcatgaaggaggagctgagg
cgcagtgtcccggggagcacccccctgcggaggagggggcccagccagctctcccaagag
gcccaggcggtggccggagcccttcctggagtgatcaccttctctcaagattacgtggca
aatgaactcactcagaacttcttcaccatcactcagaagattcagaagaaagtcacgggt
tcccggaacgccactgagctctcaaaaatgttccctgtcctccctggttctcacttgctg
ctcaataaccctgcgctggagttcatcaaatacgtgtgcaaggttctgtctctggacacg
aacatcacgaaccaggtgaacaagctgaaccgggacctgctgcgcctggtggacgttggc
gagttctcagaggaggcccagttccgagacccctgccgttcctacgtgctccctgaggtc
atctgccgcagctgtaacttctgccgggacctggacctgtgcaaagagccctccttctct
caggacggggctgtgctgcctcagtggctctgctccaactgcctggttgcctatgactca
tcagtcatcgagatggccctggtggaagccgtgcagaagaaactgatggccttcactctg
caggacctgatctgcctcaagtgccggggtgtgaaggagaccaacatgcctgtgtactgc
agctgtgccggggacttcgccctcaccatccgcaccaaggtcttcatggaccagattaga
atcttccagaacatcgcccagcactatggcatgtcgtacctcatggagaccctggagtgg
ctgctgcagaagaaccttcagctgggccattag
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integrated database retrieval system
