Puma concolor (puma): 112855216 Help Entry 112855216         CDS       T08890                                  Symbol NOS2 Name (RefSeq) nitric oxide synthase, inducible   KO K13241   nitric-oxide synthase, inducible [EC:1.14.13.39] Organism pcoo  Puma concolor (puma) Pathway pcoo00220   Arginine biosynthesis pcoo00330   Arginine and proline metabolism pcoo01100   Metabolic pathways pcoo04020   Calcium signaling pathway pcoo04066   HIF-1 signaling pathway pcoo04146   Peroxisome pcoo04371   Apelin signaling pathway pcoo04926   Relaxin signaling pathway pcoo05010   Alzheimer disease pcoo05014   Amyotrophic lateral sclerosis pcoo05022   Pathways of neurodegeneration - multiple diseases pcoo05133   Pertussis pcoo05140   Leishmaniasis pcoo05142   Chagas disease pcoo05145   Toxoplasmosis pcoo05146   Amoebiasis pcoo05152   Tuberculosis pcoo05200   Pathways in cancer pcoo05222   Small cell lung cancer Brite KEGG Orthology (KO) [BR:pcoo00001]  09100 Metabolism   09105 Amino acid metabolism    00220 Arginine biosynthesis     112855216 (NOS2)    00330 Arginine and proline metabolism     112855216 (NOS2)  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     112855216 (NOS2)    04066 HIF-1 signaling pathway     112855216 (NOS2)    04020 Calcium signaling pathway     112855216 (NOS2)  09140 Cellular Processes   09141 Transport and catabolism    04146 Peroxisome     112855216 (NOS2)  09150 Organismal Systems   09152 Endocrine system    04926 Relaxin signaling pathway     112855216 (NOS2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     112855216 (NOS2)   09162 Cancer: specific types    05222 Small cell lung cancer     112855216 (NOS2)   09171 Infectious disease: bacterial    05133 Pertussis     112855216 (NOS2)    05152 Tuberculosis     112855216 (NOS2)   09174 Infectious disease: parasitic    05146 Amoebiasis     112855216 (NOS2)    05145 Toxoplasmosis     112855216 (NOS2)    05140 Leishmaniasis     112855216 (NOS2)    05142 Chagas disease     112855216 (NOS2)   09164 Neurodegenerative disease    05010 Alzheimer disease     112855216 (NOS2)    05014 Amyotrophic lateral sclerosis     112855216 (NOS2)    05022 Pathways of neurodegeneration - multiple diseases     112855216 (NOS2) Enzymes [BR:pcoo01000]  1. Oxidoreductases   1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen    1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor     1.14.13.39  nitric-oxide synthase (NADPH)      112855216 (NOS2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  NO_synthase FAD_binding_1 NAD_binding_1 Flavodoxin_1 Motif Other DBs NCBI-GeneID:  112855216 NCBI-ProteinID:  XP_025774575 UniProt:  A0A6P6HFQ8 LinkDB All DBs Position Unknown AA seq 1122 aa AA seqDB search MACPWQFLFKAKSHQYNLTEETDINNNVGKAVRAPSGLVTQDDPKCHSLSKHRNEPPQSL TGTVKTVPESLGKLDMPPSACPRHVRIKNWGSGMTFQDTLHHKAKGDLACRSKSCLGAIM NPKSLTRGPRDKPTPPDELLPQAIEFVNQYYSSFKEAKIEEHLARVEAVTKEIETTGTYQ LTGDELIFATKQAWRNAPRCIGRIQWSNLQVFDARSCSTAQEMFEHICRHVRYATNNGNI RSAITVFPQRSDGKHDFRIWNAQLIRYAGYQMPDGTILGDPASVEFTQLCIDLGWKPKYG RFDVVPLVLQADGGDPELFEIPPDLVLEVPMEHPKYEWFRELELKWYALPAVANMLLEVG GLEFPGCPFNGWYMGTEIGVRDFCDIQRYNILEEVGRRMGLETHKLASLWKDRAVIEINV AVLHSFQKQNVTIMDHHSAAESFMKYMQNEYRSRGGCPADWIWLVPPISGSITPVFHQEM LNYVLSPFFYYQVEAWKTHIWQDEKRRPRRRKIPFKVLVQAVLFASMLMRKTMASRVRAT ILFATETGKSETLARDLGALFSCAFNPKKLKKSLFMLKELTNKFRYAVFGLGSSMYPQFC AFAHDIDQKLSHLGASQLAPTGEGDELSGQEEAFRSWAVQTFKAACETFDVRGKHRVQIP KLYTSNVTWDPHHYRLVRDSQPLDLNKALGSMHAKNVFTMRLKSQRNLQSAKSSRTTLLV ELSCEDSHRLSYLPGEHLGVFPGNQLALVKGILERVVDGPAPHQPVHLETLSESGSYWVR DKRLPPCSLSQALTYFLDITTPPTQLLLRKLAQLATEEAERQRLEILCQPSEYNKWKFTN SPTFLEVLEEFPSLRVSAGFLLSQLPILKPRYYSISSSRACAPTEVHLTVAVLTYRTRDG QGPLHHGVCSTWLSSLKPQDPVPCFVRSAGGFQLPEDPSQPCILIGPGTGIAPFRSFWQQ RLHDAEHKGLRGSRMTLVFGCRRPDEDHLYREEMLEMAQKGVLHEVHTAYSRLPGQPKVY VQDILRQQLASEVLRVLHEEQGHLYVCGDVRMARDVAQTLKHLLAAKLSLSEEQVEDYFF QLKSQKRYHEDIFGAVFPYEVKKDGAARQPSDPRVPAAHGTS NT seq 3369 nt NT seq  +upstreamnt  +downstreamnt atggcctgtccctggcagtttctgttcaaggccaaatcccaccagtacaacttgactgag gaaacagacatcaacaacaatgtggggaaggccgtccgggccccctctggtctagtgaca caggatgaccccaagtgtcacagcctcagcaaacaccggaatgagcccccccagtccctc acggggacagtaaagacagttccagaatccctggggaagctggatatgcccccgtcggcc tgcccacggcacgtgaggatcaaaaactggggcagtgggatgactttccaagacacactt caccacaaggccaaaggggatcttgcttgcaggtctaagtcttgtctgggagccatcatg aaccccaaaagtttgaccagaggacccagggacaagcctacccccccagacgagcttcta cctcaagctatcgaatttgtcaaccagtattacagctccttcaaagaggcaaaaatagag gaacatctggccagggtggaagcagtaacaaaggagatagaaacaacaggaacctatcag ctgacgggagatgagctcatcttcgccaccaagcaggcttggcgcaacgccccccgctgc atcgggaggatccagtggtcaaacctacaggtcttcgacgcccggagctgttccactgcc caggaaatgttcgagcacatctgcagacacgtgcgttatgctaccaacaatggcaacatc aggtcggccatcaccgtgttcccccagcggagtgatgggaagcatgacttccggatctgg aacgctcagctcatccggtatgctggctaccagatgcctgatggcaccatcctgggggac cctgccagcgtggagttcacccagctgtgcatcgacctgggctggaagcccaagtacggc cgctttgatgtggtgcctctggtcctgcaggctgatggcggagaccctgagctctttgaa atcccgcctgacctcgtgctcgaggtgcccatggaacatcccaagtatgagtggttccgt gaactggagctaaagtggtatgccctgcctgccgtggccaacatgctgctcgaggtgggt ggcctggagttcccagggtgccccttcaacggctggtacatgggcacggagatcggggtc cgggacttctgtgacattcagcgctacaacatcctggaggaagtgggcagaaggatgggc ctggaaacgcacaagctggcctcactctggaaggaccgggctgtcattgagatcaacgtc gccgtgctgcacagtttccagaagcaaaacgtgaccatcatggaccaccactcggctgcg gagtccttcatgaagtacatgcagaacgagtaccggtcccgagggggctgtcctgccgac tggatttggctggtgcccccgatttctggcagcatcactcccgtgttccaccaggagatg ttaaactatgtcctgtcccctttcttctactaccaggtggaggcctggaaaacccacatc tggcaggatgagaagcggagaccccggagaagaaagattccgttcaaagtcttggttcaa gctgtgctcttcgcctccatgctgatgcgcaagaccatggcgtcccgagtgagagccaca atcctctttgcgacggagacaggaaagtcagaaacactggcccgggacctaggggccttg ttcagctgtgccttcaaccccaagaaactgaaaaaatccctcttcatgctgaaagagctt accaacaagttcaggtatgccgtgttcggcctcggctccagcatgtaccctcagttctgt gcctttgctcatgacatcgaccagaagctgtcccatctgggggcctctcagcttgcccca acaggggaaggggacgagctcagtggacaggaggaagccttccgcagctgggccgtgcaa accttcaaggcagcctgtgagacgttcgatgtgcgaggcaagcaccgcgttcagatcccc aagctctacacctccaatgtgacctgggacccgcaccactacaggctcgtgcgggactca cagcctctggacctcaacaaagccctcggcagtatgcacgccaagaacgtgttcaccatg aggctcaaatcacagcggaatctccagagtgcgaaatccagccgcaccaccctcctggtg gagctctcctgtgaggacagccaccggctgagctacctgcctggagagcacctcggggtt ttcccaggcaaccagctggctctggtaaaaggcatcttggagcgagtggtggacggccct gcgccccaccaaccggtgcacctggagaccctcagcgagagcggaagctactgggtcaga gacaagcggctgcccccgtgctccctcagccaggccctcacctacttcctggatatcacc acccccccaacccagctgctgctccgcaaattggcacagctggccacagaagaggcagag aggcagaggctggagatcctgtgccagccctcagagtacaacaaatggaagttcaccaac agccccacattcctggaggtactggaggagttcccatccctgcgggtatctgctggcttc ctgctctcccagctgcctattctgaaaccccggtactactccatcagctcctccagggcc tgtgcacccacggaggtccacctcactgtggctgtgctcacctaccgcacccgagatggc caaggtcccttgcaccacggcgtctgcagcacatggctcagcagcctgaagccccaagac ccagtaccctgctttgtgagaagtgccggcggcttccagctccctgaggacccctcccaa ccttgcatcctcattgggcctggcacaggcatcgcccccttccgcagcttctggcagcag cggctccatgatgctgagcacaaagggctccggggcagccgcatgaccctggtgttcggg tgccgccgcccggatgaggaccacctctatcgggaggagatgttggagatggcccagaag ggggtgctgcatgaggttcacacagcctactctcgcctgcctggccagcccaaggtctat gttcaagacatcctgaggcagcagctggccagcgaggtgctccgcgtgctccatgaggag caaggccacctttatgtctgtggggatgtgcgtatggcccgggatgtggcccaaaccctg aagcacctgctggccgccaagctgagcctgagcgaggagcaggtggaggactatttcttc caacttaagagccagaagcgctatcatgaagacatctttggtgctgtatttccctacgag gtgaaaaaggatggggcagcaaggcagcccagcgatcccagagttccagcggcccacggg acaagttaa

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