Puma concolor (puma): 112855387 Help Entry 112855387         CDS       T08890                                  Symbol HIF1A Name (RefSeq) hypoxia-inducible factor 1-alpha   KO K08268   hypoxia-inducible factor 1 alpha Organism pcoo  Puma concolor (puma) Pathway pcoo04066   HIF-1 signaling pathway pcoo04137   Mitophagy - animal pcoo04140   Autophagy - animal pcoo04148   Efferocytosis pcoo04659   Th17 cell differentiation pcoo04919   Thyroid hormone signaling pathway pcoo05167   Kaposi sarcoma-associated herpesvirus infection pcoo05200   Pathways in cancer pcoo05205   Proteoglycans in cancer pcoo05208   Chemical carcinogenesis - reactive oxygen species pcoo05211   Renal cell carcinoma pcoo05230   Central carbon metabolism in cancer pcoo05231   Choline metabolism in cancer pcoo05235   PD-L1 expression and PD-1 checkpoint pathway in cancer Brite KEGG Orthology (KO) [BR:pcoo00001]  09130 Environmental Information Processing   09132 Signal transduction    04066 HIF-1 signaling pathway     112855387 (HIF1A)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     112855387 (HIF1A)    04137 Mitophagy - animal     112855387 (HIF1A)    04148 Efferocytosis     112855387 (HIF1A)  09150 Organismal Systems   09151 Immune system    04659 Th17 cell differentiation     112855387 (HIF1A)   09152 Endocrine system    04919 Thyroid hormone signaling pathway     112855387 (HIF1A)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     112855387 (HIF1A)    05205 Proteoglycans in cancer     112855387 (HIF1A)    05208 Chemical carcinogenesis - reactive oxygen species     112855387 (HIF1A)    05230 Central carbon metabolism in cancer     112855387 (HIF1A)    05231 Choline metabolism in cancer     112855387 (HIF1A)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     112855387 (HIF1A)   09162 Cancer: specific types    05211 Renal cell carcinoma     112855387 (HIF1A)   09172 Infectious disease: viral    05167 Kaposi sarcoma-associated herpesvirus infection     112855387 (HIF1A)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03000 Transcription factors [BR:pcoo03000]     112855387 (HIF1A) Transcription factors [BR:pcoo03000]  Eukaryotic type   Basic helix-loop-helix (bHLH)    Factors with PAS domain     112855387 (HIF1A) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  bHLH_HIF1A PAS_3 PAS_11 HIF-1a_CTAD PAS HIF-1 PAS_9 PAS_4 HLH DDRGK Motif Other DBs NCBI-GeneID:  112855387 NCBI-ProteinID:  XP_025774817 UniProt:  A0A6P6HGF3 LinkDB All DBs Position Unknown AA seq 824 aa AA seqDB search MEGAGGANDKKKISSERRKEKSRDAARSRRSKESEVFYELAHQLPLPHNVSSHLDKASVM RLTISYLRVRKLLDAGDLDIEDEMKAQMNCFYLKALDGFVMVLTDDGDMIYISDNVNKYM GLTQFELTGHSVFDFTHPCDHEEMREMLTHRNGLVKKGKEQNTQRSFFLRMKCTLTSRGR TMNIKSATWKVLHCTGHIHVYDTNSNQSQCGYKKPPMTCLVLICEPIPHPSNIEIPLDSK TFLSRHSLDMKFSYCDERITELMGYEPEELLGRSIYEYYHALDSDHLTKTHHDMFTKGQV TTGQYRMLAKRGGYVWVETQATVIYNTKNSQPQCIVCVNYVVSGIIQHDLIFSLQQTECV LKPVESSDMKMTQLFTKVESEDTSSLFDKLKKEPDALTLLAPAAGDTIISLDFGSNDTET DDQQLEEVPLYNDVMLPSSNEKLQNINLAMSPLPASETPKPLRSSADPALNQEVVLKLEP NPESLELSFTMPQIQDQPASPSDGSTRQSSPEPTSPSEYCFDVDSDMVNEFKLELVEKLF AEDTEAKNPFSTQDTDLDLEMLAPYIPMDDDFQLRSFDQLSPLESSSTSPQSVGTITVFQ PAQMQEEPPVTTTSTTATTDELKTVTKDGIEDIKILIASPSPTHVPKVTTGATTSLYGDT GSRTASPNRAGKGVIEQTEKSHPRSPNVLSVTLSQRTTIPEEELNPKILALQNAQRKRKI EHDGSLFQAVGIGTLLQQPDDRATTTSLSWKRVKGCKSSEQNGMEQKTIILIPSDLACRL LGQSMDESGLPQLTSYDCEVNAPVQGSRNLLQGEELLRALDQVN NT seq 2475 nt NT seq  +upstreamnt  +downstreamnt atggagggcgccggcggcgcgaacgacaagaaaaagataagttctgaacgtcgaaaagaa aagtctagagatgcagcgagatctcggcgaagtaaagaatctgaagttttctatgaactt gctcatcagttgccacttccccataatgtgagctcgcatctcgataaggcttctgttatg aggctcaccatcagctatttgcgtgtgaggaaacttctggatgctggtgatttagatatt gaagatgaaatgaaggcacagatgaattgcttttatttgaaagccttggatggttttgtt atggttctcacagatgatggtgacatgatctacatttctgataatgtgaacaagtacatg ggattaactcagtttgaactaactggacacagtgtgtttgattttactcatccatgtgac catgaagaaatgagagagatgcttacacatagaaatggccttgtgaagaagggtaaagag cagaatacacagcgaagcttttttctcagaatgaagtgtaccctaactagccgagggaga accatgaacataaagtcagcaacgtggaaagtacttcactgcacaggccatattcatgtc tacgataccaatagtaaccaatctcagtgtgggtataagaaaccacccatgacgtgcttg gtgctgatttgtgaacccattcctcatccatcaaatattgaaattcctttagatagcaag acttttctgagtcgtcatagtctggatatgaaattttcttattgtgatgaaagaattact gaattgatgggatacgagccagaggaacttttgggccgctcgatatatgaatattaccac gctttggactctgaccatctgaccaaaactcatcatgacatgtttactaaaggtcaagtc accacaggacagtacaggatgcttgccaaaagaggtggatatgtctgggttgaaactcaa gcgaccgtcatatataacactaagaactctcaaccacagtgcattgtatgtgtaaattac gttgtgagtggtattattcagcacgacttgattttctcccttcaacaaacagaatgtgtc ctcaaaccagttgaatcttcagatatgaaaatgactcagctgttcaccaaagttgaatca gaagacacaagtagtctgtttgataaacttaagaaggaacctgatgctttaactttgctg gcaccagctgctggagacacaatcatatctttagatttcggcagcaatgacacagaaact gatgaccagcaacttgaggaagttccattgtataatgatgtaatgcttccctcatccaat gaaaaattacagaacataaatttggcaatgtctccattacctgcttctgaaactccaaag ccacttcgaagtagtgctgaccctgcactcaatcaagaagttgtactaaaattagagcca aatccagaatcactggaactttcttttactatgccccagattcaagatcagccagctagt ccttctgatggaagcactagacagagttcacctgagcctaccagtcccagtgaatattgt tttgatgtggatagtgatatggtcaatgaatttaagctggaattggtagagaaacttttt gctgaagacacagaagccaagaatccattttccacccaggacactgatttagacttggag atgttagctccttacatcccaatggatgatgacttccagttacggtcctttgatcagttg tcgccactggaaagcagttctacaagccctcaaagcgtgggcacaattacagtattccag ccggctcaaatgcaggaggaacctcctgttaccactaccagtaccactgccaccactgat gaattaaaaacagtgacaaaagatggtatagaagacattaaaatactgattgcatctcca tctcctacccatgtacccaaagtaactactggtgccacaacatcactgtatggtgatact ggaagtcggacagcctcaccaaacagagcaggaaaaggagtcatagaacagacagaaaaa tctcatccaagaagccctaatgtgttgtctgtcactttgagtcaaagaactaccattcct gaagaagaactaaatccaaagatactagctttgcagaatgctcagagaaagcgaaaaata gaacatgacggttcactttttcaagcagtaggaattggaacattattacagcagccagat gatcgtgcaactactacatcactttcttggaaacgcgtaaaaggatgcaaatctagtgag cagaatggaatggagcaaaagacaattattttaataccctctgatttagcgtgtagactg ctggggcaatcaatggatgagagtggattaccacaactgaccagttatgattgtgaagtt aatgctcctgtacaaggcagcagaaacctactgcagggtgaagaattactcagagctttg gatcaagttaactga

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