Puma concolor (puma): 112855479
Help
Entry
112855479 CDS
T08890
Symbol
IGF1R
Name
(RefSeq) insulin-like growth factor 1 receptor
KO
K05087
insulin-like growth factor 1 receptor [EC:
2.7.10.1
]
Organism
pcoo
Puma concolor (puma)
Pathway
pcoo01521
EGFR tyrosine kinase inhibitor resistance
pcoo01522
Endocrine resistance
pcoo04010
MAPK signaling pathway
pcoo04014
Ras signaling pathway
pcoo04015
Rap1 signaling pathway
pcoo04066
HIF-1 signaling pathway
pcoo04068
FoxO signaling pathway
pcoo04081
Hormone signaling
pcoo04114
Oocyte meiosis
pcoo04140
Autophagy - animal
pcoo04144
Endocytosis
pcoo04150
mTOR signaling pathway
pcoo04151
PI3K-Akt signaling pathway
pcoo04152
AMPK signaling pathway
pcoo04211
Longevity regulating pathway
pcoo04213
Longevity regulating pathway - multiple species
pcoo04510
Focal adhesion
pcoo04520
Adherens junction
pcoo04550
Signaling pathways regulating pluripotency of stem cells
pcoo04730
Long-term depression
pcoo04913
Ovarian steroidogenesis
pcoo04914
Progesterone-mediated oocyte maturation
pcoo05200
Pathways in cancer
pcoo05202
Transcriptional misregulation in cancer
pcoo05205
Proteoglycans in cancer
pcoo05214
Glioma
pcoo05215
Prostate cancer
pcoo05218
Melanoma
pcoo05224
Breast cancer
pcoo05225
Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:
pcoo00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
112855479 (IGF1R)
04014 Ras signaling pathway
112855479 (IGF1R)
04015 Rap1 signaling pathway
112855479 (IGF1R)
04066 HIF-1 signaling pathway
112855479 (IGF1R)
04068 FoxO signaling pathway
112855479 (IGF1R)
04151 PI3K-Akt signaling pathway
112855479 (IGF1R)
04152 AMPK signaling pathway
112855479 (IGF1R)
04150 mTOR signaling pathway
112855479 (IGF1R)
09133 Signaling molecules and interaction
04081 Hormone signaling
112855479 (IGF1R)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
112855479 (IGF1R)
04140 Autophagy - animal
112855479 (IGF1R)
09143 Cell growth and death
04114 Oocyte meiosis
112855479 (IGF1R)
09144 Cellular community - eukaryotes
04510 Focal adhesion
112855479 (IGF1R)
04520 Adherens junction
112855479 (IGF1R)
04550 Signaling pathways regulating pluripotency of stem cells
112855479 (IGF1R)
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
112855479 (IGF1R)
04914 Progesterone-mediated oocyte maturation
112855479 (IGF1R)
09156 Nervous system
04730 Long-term depression
112855479 (IGF1R)
09149 Aging
04211 Longevity regulating pathway
112855479 (IGF1R)
04213 Longevity regulating pathway - multiple species
112855479 (IGF1R)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
112855479 (IGF1R)
05202 Transcriptional misregulation in cancer
112855479 (IGF1R)
05205 Proteoglycans in cancer
112855479 (IGF1R)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
112855479 (IGF1R)
05214 Glioma
112855479 (IGF1R)
05218 Melanoma
112855479 (IGF1R)
05215 Prostate cancer
112855479 (IGF1R)
05224 Breast cancer
112855479 (IGF1R)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
112855479 (IGF1R)
01522 Endocrine resistance
112855479 (IGF1R)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pcoo01001
]
112855479 (IGF1R)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
pcoo04090
]
112855479 (IGF1R)
Enzymes [BR:
pcoo01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
112855479 (IGF1R)
Protein kinases [BR:
pcoo01001
]
Receptor tyrosine kinases (RTK)
INSR family [OT]
112855479 (IGF1R)
CD molecules [BR:
pcoo04090
]
Proteins
112855479 (IGF1R)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
Pkinase
Furin-like
fn3
Kinase-like
Ig_DSCAM-DSCAML_C
Motif
Other DBs
NCBI-GeneID:
112855479
NCBI-ProteinID:
XP_025774926
UniProt:
A0A6P6HHW2
LinkDB
All DBs
Position
Unknown
AA seq
1279 aa
AA seq
DB search
MCFSFCGPGIDIRNDYQQLKRLENCTVIEGYLHILLISKAEDYRSYRFPKLTVITEYLLL
FRVAGLESLGDLFPNLTVIRGWKLFYNYALVIFEMTNLKDIGLYNLRNITRGAIRIEKNA
DLCYLSTVDWSLILDAVSNNYIVGNKPPKECGDLCPGTMEEKPLCEKTTINNEYNYRCWT
TNRCQKMCPSACGKRACTDSNECCHPECLGSCSAPDNDTACVACRHYYYAGVCVPTCPPN
TYRFEGWRCVDRDFCANIPSAESSDSEGFVIHDGECMQECPSGFIRNGSQSMYCIPCEGP
CPKVCEEEKKTKTIDSVTSAQMLQGCTIFKGNLLINIRRGNNIASELENFMGLIEVVTGY
VKIRHSHALVSLSFLKNLRQILGEEQLEGNYSFYVLDNQNLQQLWDWGHRNLTIKAGKMY
FAFNPKLCVSEIYRMEEVTGTKGRQSKGDINTRNNGERASCESDVLHFTSTTTWKNRIII
TWHRYRPPDYRDLISFTVYYKEASLSPVIGFPGAGTRATNGIPSIPLDVLSASNSSSQLI
VKWNPPSLPNGNLSYYIVRWQRQPQDSYLYRHNYCSKDKIPIRKYADGTIDVEEVTENPK
TEVCSGEKGPCCACPKTEAEKQAEKEEAEYRKVFENFLHNSIFVPRPERKRRDVTQVTNT
TMSSRSRNITVADTYNITDPEELETEYPFFESRVDNKERTVISNLRPFTLYRIDIHSCNH
EAEKLGCSASNFVFARTMPAEGADDIPGPVTWESRPENSIFLKWPEPENPNGLILMYEIK
YGSQIEDQRECVSRQEYRKYGGAKLNRLNPGNYTARIQATSLSGNGSWTDPVFFYVPAKI
TYENFIHLIIALPVAVLLIVGGLVIMLYVFHRKRNNSRLGNGVLYASVNPEYFSAADVYV
PDEWEVAREKITMSRELGQGSFGMVYEGVAKGVVKDEPETRVAIKTVNEAASMRERIEFL
NEASVMKEFNCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSYLRSLRPEIENNPVLAPPS
LSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMVAEDFTVKIGDFGMTRDIYETDYYRK
GGKGLLPVRWMSPESLKDGVFTTHSDVWSFGVVLWEIATLAEQPYQGLSNEQVLRFVMEG
GLLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIISSIKDEMEPGFREVSFYYSEENKPP
EPEELDLEPEDMESVPLDPSASSSSLPLPDRHSGHKAENGPGPGVLVLRASFDERQPYAH
MNGGRKNERALPLPQSSTC
NT seq
3840 nt
NT seq
+upstream
nt +downstream
nt
atgtgcttctcgttctgcgggccgggcatcgatatccgtaacgactatcagcagctgaag
cgcctggagaactgcacggtgattgagggctacctccacatcctgctcatctccaaggca
gaggactaccgcagctaccgcttccccaagctcacggtcatcaccgagtacttgctgctg
ttccgcgtggccggcctcgagagtctcggggacctcttcccgaacctcacggtcatccgc
ggctggaaactcttctacaactacgccctggtcatctttgagatgaccaatctcaaggat
attgggctttacaatctgaggaacattacccggggggccatcaggattgagaaaaatgct
gacctctgttacctctccacggtggactggtccctaatcctggatgcggtgtctaataac
tacatcgtgggaaacaagcccccaaaggaatgcggggacctgtgtccggggacgatggag
gagaagcccttgtgcgagaagacgaccatcaacaatgaatacaactaccgctgctggacg
accaaccgctgccagaaaatgtgcccgagcgcgtgcgggaagcgggcgtgcacggacagc
aacgagtgctgtcaccccgagtgcctgggcagctgcagcgcgccggacaacgacacggcc
tgcgtggcctgcaggcattactactacgccggcgtctgcgtgcccacctgcccgcccaac
acctaccgctttgagggctggcgctgcgtggaccgcgacttctgcgccaacatccccagc
gccgagagcagcgactccgaggggttcgtgatccatgatggcgagtgtatgcaggagtgc
ccctcggggttcatccggaacgggagtcagagcatgtactgtatcccttgtgaaggtcct
tgccccaaggtctgcgaggaggagaagaaaacaaagaccattgattctgttacctctgct
caaatgctccaaggatgcaccatcttcaagggcaatctgctcattaatatccgccgaggc
aataacattgcctcggagctggagaacttcatgggactcatcgaggtggtgacaggctat
gtgaagatccgccattcccacgccttggtctccttgtccttcctcaaaaaccttcgccag
atcttaggagaggagcagctggaggggaactactctttctatgtcctcgacaaccagaac
ctgcagcagctctgggactggggccaccgcaatctgaccatcaaagctgggaagatgtac
ttcgctttcaaccccaagttgtgcgtctccgaaatttaccgcatggaggaggtgaccggg
actaaggggcgccagagcaaaggggacatcaatacgaggaacaatggagagcgagcctcc
tgtgaaagtgacgtcctgcacttcacctctacgaccacgtggaagaaccgcatcatcata
acctggcaccggtaccggccccctgactacagggacctcatcagcttcaccgtctactac
aaggaggcgtctctttccccagtgattggcttccccggggctggaaccagagccaccaat
ggcattccttccattcccctggatgttctttcggcatcaaactcctcttctcagctcatc
gtgaagtggaacccgccgtccctgcccaacggcaacctgagttactacatcgtgaggtgg
cagcggcagccccaggacagctacctttaccgccacaactactgctccaaagacaaaatc
cccatcaggaagtatgccgatggcaccattgacgtcgaggaggtgaccgagaaccccaag
accgaagtgtgcagcggagagaaggggccttgctgtgcctgccccaaaaccgaggccgag
aagcaggcggagaaggaggaggctgagtaccgcaaagtcttcgagaacttcctgcacaac
tccatctttgtgcccagacctgaaaggaagcggagagatgtcacacaagtcaccaacacc
accatgtccagccgaagcaggaacatcacggtggcagacacctataatatcacagacccc
gaagagctcgagacagaataccctttctttgagagcagagtggataacaaggagagaact
gtgatctctaacctccggcctttcactttgtaccgcattgacatccacagctgtaaccac
gaggctgagaagctgggctgcagcgcctccaactttgtctttgcaagaaccatgcctgca
gaaggagcagacgacattcctgggccggtgacctgggagtcaaggcctgaaaactccatc
tttttaaagtggccggaacctgagaatcccaatggactgattctaatgtatgaaataaaa
tatggatcacaaatcgaggatcagcgggaatgtgtatccagacaggagtaccggaagtat
ggaggcgccaagcttaaccggctcaacccggggaactatacggcccggatccaggccacc
tctctctctgggaatgggtcgtggacggatcccgtgttcttctacgtccccgccaaaata
acatatgaaaatttcatccacctgatcatcgctctgcctgttgccgtcctgctgatagtg
gggggactggttatcatgttgtacgtcttccacagaaaaagaaataacagcaggctgggg
aatggagtgctgtatgcttcggtgaacccagagtacttcagtgccgcagatgtgtatgta
cctgatgagtgggaggttgctcgggagaaaatcaccatgagccgagagctggggcagggc
tcgtttgggatggtctacgaaggagttgccaaaggcgtggttaaagatgagcccgaaacc
agggtggccatcaaaacggtgaacgaggccgcgagcatgcgtgaaaggattgaatttctc
aacgaggcttcagtgatgaaggagttcaattgtcaccatgtggtgcggttgctgggcgtg
gtgtcccagggccagccgacgctggtcatcatggaactgatgacgcggggcgatctcaaa
agttatctcaggtctctgaggccagaaatagagaataatccagtcctagcacctccaagc
ctaagcaagatgatccagatggctggagagattgcagacggcatggcatacctcaacgcc
aacaagtttgtccacagggaccttgctgcccggaactgcatggtggctgaagatttcacg
gtcaaaatcggagatttcggtatgacgagagatatctacgagacagactattaccggaaa
ggagggaaggggctgctgcctgtgcgctggatgtcacccgagtccctcaaggatggggtc
ttcaccactcactctgacgtctggtccttcggggtcgttctctgggagatcgccacgctg
gccgagcagccgtaccagggcttgtccaacgagcaagtgcttcgcttcgtcatggagggc
ggccttctggacaagccggacaactgccctgacatgctgtttgaactgatgcgcatgtgc
tggcagtacaaccccaagatgaggccttccttcctggagatcatcagcagcatcaaggac
gagatggaacccggcttccgggaggtctccttctactacagcgaggagaacaagccgccc
gagccggaggagctggatctggagccggaggacatggagagcgtccccctggacccctcc
gcctcctcgtcctccctgccgctgcccgacagacactcaggacacaaggccgagaacggc
ccgggccccggcgtgctggttctccgagccagcttcgacgagagacagccttacgcgcac
atgaacgggggacgcaagaacgagagggccttgcctctgccccagtcttcgacctgctga
DBGET
integrated database retrieval system
