Puma concolor (puma): 112855609 Help Entry 112855609         CDS       T08890                                  Symbol PLA2G4F Name (RefSeq) cytosolic phospholipase A2 zeta   KO K16342   cytosolic phospholipase A2 [EC:3.1.1.4] Organism pcoo  Puma concolor (puma) Pathway pcoo00564   Glycerophospholipid metabolism pcoo00565   Ether lipid metabolism pcoo00590   Arachidonic acid metabolism pcoo00591   Linoleic acid metabolism pcoo00592   alpha-Linolenic acid metabolism pcoo01100   Metabolic pathways pcoo04010   MAPK signaling pathway pcoo04014   Ras signaling pathway pcoo04072   Phospholipase D signaling pathway pcoo04217   Necroptosis pcoo04270   Vascular smooth muscle contraction pcoo04370   VEGF signaling pathway pcoo04611   Platelet activation pcoo04664   Fc epsilon RI signaling pathway pcoo04666   Fc gamma R-mediated phagocytosis pcoo04724   Glutamatergic synapse pcoo04726   Serotonergic synapse pcoo04730   Long-term depression pcoo04750   Inflammatory mediator regulation of TRP channels pcoo04912   GnRH signaling pathway pcoo04913   Ovarian steroidogenesis pcoo04921   Oxytocin signaling pathway pcoo05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:pcoo00001]  09100 Metabolism   09103 Lipid metabolism    00564 Glycerophospholipid metabolism     112855609 (PLA2G4F)    00565 Ether lipid metabolism     112855609 (PLA2G4F)    00590 Arachidonic acid metabolism     112855609 (PLA2G4F)    00591 Linoleic acid metabolism     112855609 (PLA2G4F)    00592 alpha-Linolenic acid metabolism     112855609 (PLA2G4F)  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     112855609 (PLA2G4F)    04014 Ras signaling pathway     112855609 (PLA2G4F)    04370 VEGF signaling pathway     112855609 (PLA2G4F)    04072 Phospholipase D signaling pathway     112855609 (PLA2G4F)  09140 Cellular Processes   09143 Cell growth and death    04217 Necroptosis     112855609 (PLA2G4F)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     112855609 (PLA2G4F)    04664 Fc epsilon RI signaling pathway     112855609 (PLA2G4F)    04666 Fc gamma R-mediated phagocytosis     112855609 (PLA2G4F)   09152 Endocrine system    04912 GnRH signaling pathway     112855609 (PLA2G4F)    04913 Ovarian steroidogenesis     112855609 (PLA2G4F)    04921 Oxytocin signaling pathway     112855609 (PLA2G4F)   09153 Circulatory system    04270 Vascular smooth muscle contraction     112855609 (PLA2G4F)   09156 Nervous system    04724 Glutamatergic synapse     112855609 (PLA2G4F)    04726 Serotonergic synapse     112855609 (PLA2G4F)    04730 Long-term depression     112855609 (PLA2G4F)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     112855609 (PLA2G4F)  09160 Human Diseases   09161 Cancer: overview    05231 Choline metabolism in cancer     112855609 (PLA2G4F) Enzymes [BR:pcoo01000]  3. Hydrolases   3.1  Acting on ester bonds    3.1.1  Carboxylic-ester hydrolases     3.1.1.4  phospholipase A2      112855609 (PLA2G4F) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  cPLA2_C2 PLA2_B C2 Motif Other DBs NCBI-GeneID:  112855609 NCBI-ProteinID:  XP_025775019 UniProt:  A0A6P6HGX7 LinkDB All DBs Position Unknown AA seq 849 aa AA seqDB search MLWALWPRWLAGKGLPLLGAVLLRKRDKRGPQWRQWRRETHPYYDLQVKVLRARNIQGTD LLSKADCYVELHLPTASPSPAQTRMVANCSDPEWNETFHYQIHGAVKNVLELTLCDKDIL GSDQLSLLLFDLRSLKPGQPYRHIFPLNHQDSQELQVEFVLENSQVPASEVITNGVLVAQ PCLRIQGTLREDGTAPHREYGSTQIQLTVPGAYEKPQFLPLQPPMEGGLPATFTFHVNPV ISSRLDVELGERLTVLQSGPSAELEAHTNKLGEGGILLSSLALGQEEQRFVALGEGQEVV LSMKAEMSSGDLDLRLGFGLCDGEREFLDKRKQIVSKALQQVLGLSQAPDSGQVPVVAVL GSGGGTRAMSSLYGSLAGLQELGLLDTVTYLSGVSGSTWCISTLYKDPAWSQVALQGPIE RAQARVCSSKMGAMSTERLQYYAQELGSLESTGHRVSLIDIWGLLIEYFLYQEKNPAKLS DQQEAVNQGQNPYPIYASINVHTNISGEDFAEWCEFTPYEVGFPKYGAYVPTELFGSEFF MGHLLQPQPEPRICYLQGVWGSAFAASLDEIFLKTAGSGLSFLDCHRGSVNLTDDCQKLQ LHDPTRLRTRLFTHQGPFSQAVLDIFTSRFTFAENCNFTRGLCLHKDYVAGREFMAWKDT HPDAFPNQLTPMRDCLCLVDGGFAINSPFPLSLLPQRAVDLILSFDYSLEAPFEVLQMTE KYCLDRGIPFPSIEVLPEDLEEPRECYLFAKAKDPRSPIVLHFPLVNRTFCTHLAPGVER QTAEEKAYGDFVVNGADTPYGMMNFTYEPEEFERLVALSRYNVLNNVETLRHALQLALER RQAGGRAGD NT seq 2550 nt NT seq  +upstreamnt  +downstreamnt atgctctgggcgctctggccaaggtggctggcaggcaaggggctgcccctcctgggggca gtgctgctgcggaagagagacaagaggggacctcagtggaggcaatggaggcgggaaacc cacccctactatgacctccaggtgaaggtgctgagggccagaaatatccagggcacagat ctcttgtccaaagctgactgctacgtggaactgcacctgcccactgcatcccctagccct gcccagacaaggatggtggctaactgcagtgaccctgagtggaacgagactttccactac cagatccatggtgctgtgaagaatgtcctggagctcaccctctgtgataaggacatcctg ggcagtgaccagctctccctgctactctttgatctgaggagcctcaagcctggccaaccc tacagacacatcttcccactcaaccaccaggattcacaggagctgcaggtggaatttgtt ctggagaacagccaggtgcctgcgtctgaagtcatcaccaatggagtcctggtggctcag ccctgtctgagaatccaggggaccctgagggaagatgggacagccccacatcgagagtat ggctctacgcagattcagctgacagtgcccggggcctacgagaagccacagttcttgccc ctgcaacctcccatggagggaggcctcccagctaccttcacctttcacgtgaacccagtg atcagctccaggctggatgtggagctgggggagaggctcacagtcctgcaaagtggtcca agtgctgagctggaggcccacaccaacaagctgggtgaggggggtatcctgctctcctct ctggccctaggccaagaggaacagcgctttgtggccctaggggagggccaggaggtggtt ctgagtatgaaggcagaaatgagctctggagaccttgacctgcgtcttggttttggcctg tgtgatggggaacgggagtttctggacaagaggaagcagatcgtgtccaaggccctgcag caggttctgggtttgagccaggcgcctgacagtggccaggtgcctgtggtggctgtgcta ggttcgggaggtggaacccgagccatgtcttccctgtacggcagcctggcagggctgcag gaacttggcctcctggacactgtgacctacctgagtggggtctctgggtctacctggtgc atctccacactctacaaggacccagcctggtcccaggtggccttgcagggccccattgag cgtgcccaggctcgggtctgcagcagtaagatgggggcgatgtccacggagcgcctacaa tactatgcccaggaactggggagcctggaaagcactggccacagagtttccctcatcgac atctggggtctcctcattgaatatttcctctaccaggagaaaaaccctgccaagctgtct gaccagcaggaggccgtcaaccagggccagaacccttatcctatctacgccagcatcaat gtccacaccaacatcagcggggaagacttcgcagaatggtgcgaattcacaccctatgag gtcggcttccccaagtacggggcttatgttcccactgagctctttggctcggagttcttc atggggcatctgctgcagccccagcccgagccccggatctgctacctgcagggtgtgtgg ggcagcgcctttgcagccagcctggatgagatcttcctgaagactgctggctcgggcctc agcttcctagactgccacagagggagtgtaaacctcacagatgactgccagaagctccag ctgcacgatcccacacgtctgaggaccaggctcttcacccaccaggggcccttctcccag gccgtgctggacatctttacttcccgctttaccttcgcggagaactgtaatttcaccagg ggcctctgcctgcacaaagactatgtggctggccgggagttcatggcctggaaagatacg caccctgacgccttccccaaccagctcactcccatgcgggactgcctgtgcctggtggat gggggctttgccatcaactctccgttcccactcagcctgctgccccagagagcggtggac ctcattctgtcctttgactactccctggaggcccctttcgaggtcttacagatgacagag aagtactgcctggaccgaggcatccccttcccaagtatcgaggtgctccccgaggacttg gaggaaccccgtgagtgctacctgttcgccaaggccaaggacccccgctctcccatcgtg ctgcactttcccctcgtcaaccgtaccttctgcacacacctggccccaggtgtggagcga caaacagccgaggagaaggcctacggggactttgtggtcaatggggcagacactccatat ggcatgatgaacttcacctatgagcctgaggagtttgagcggctggtggctctgagtcga tacaatgttctgaacaatgtggagaccttgcggcatgcgctccagctggctctggagcga aggcaggctgggggcagggctggagactga

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