Puma concolor (puma): 112856477
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Entry
112856477 CDS
T08890
Symbol
PDE8A
Name
(RefSeq) high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A isoform X1
KO
K18437
high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:
3.1.4.53
]
Organism
pcoo
Puma concolor (puma)
Pathway
pcoo00230
Purine metabolism
pcoo01100
Metabolic pathways
pcoo04927
Cortisol synthesis and secretion
pcoo04934
Cushing syndrome
pcoo05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
pcoo00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
112856477 (PDE8A)
09150 Organismal Systems
09152 Endocrine system
04927 Cortisol synthesis and secretion
112856477 (PDE8A)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
112856477 (PDE8A)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
112856477 (PDE8A)
Enzymes [BR:
pcoo01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.53 3',5'-cyclic-AMP phosphodiesterase
112856477 (PDE8A)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PDEase_I
PDE8A_N
PAS
PAS_9
PAS_4
PDE8_3rd
PAS_3
DUF5894
PAS_8
Sina_ZnF
Response_reg
Motif
Other DBs
NCBI-GeneID:
112856477
NCBI-ProteinID:
XP_025775829
UniProt:
A0A6P6HJ80
LinkDB
All DBs
Position
Unknown
AA seq
757 aa
AA seq
DB search
MRFHPDQLQVLLVFTKEDNQCNGFCRACEKAGFKCTVTKEAQAVLACFLDKHHDIIIIDH
RNPRQLDAEALCRSIRSSKLSENTIIIGVVRRTDREESSVMPLIAAGFTRRYVENPSLMA
CYNELLQLEFGEVRSQLKLRACNSIFTALEKSQEAVEITSEDRVIQYANPAFETTMGYQA
GELIGKELAEVPVNEKKAELLDTINSCIRIGKEWQGIYHAKKKNGDNVQQNVKIVPVVGQ
GGKIRHYVSIIRVCNGNNKAEKRTESVQSDPHTDNQSGKHKDRRKSSLDVRAVASRASEV
SSQRRHSSMARIHSMTIEAPITKVINIINAAQESSPMPVTEALDRVLEILRTTELYSPQF
GAKDDDPHANDLVGGLMSDGLRRLSGNEYVLSTKSLQQVPGSVVTPISLHDVPPRIARAM
ENEEYWDFDIFELEAATHKRPLIYLGLKMFARFGICEFLNCSEATLRSWLQIIEANYHSC
NPYHNSTHSADVLHATAYFLCKERIKQTLDPVDEVAALIAATIHDVDHPGRTNSFLCNAG
SELAILYNDTAVLESHHAALAFQLTTRDDKCNIFKNMERNDYRTLRQGIIDMVLATEMTK
HFEHVNKFVNSINKPLAALEENEETNKDEEAINTMLRTPENRTLIKRMLIKCADVSNPCR
PLEQCIEWAARISEEYFSQTDEEKQQDLPVVMPVFDRNTCSIPKSQISFIDYFITDMFDA
WDAFVDLPELMQHLDNNFKYWKGLDEMQLRSLRPPPE
NT seq
2274 nt
NT seq
+upstream
nt +downstream
nt
atgagatttcatccagatcaactccaggtacttttagtgtttaccaaagaagataaccag
tgtaatggattctgcagggcgtgtgaaaaagcagggtttaagtgcacagttaccaaggag
gcccaggctgtccttgcctgtttcctggacaagcatcacgacatcatcatcatagaccac
agaaacccccgacagctggacgcggaggccctgtgcaggtctatcaggtcatcaaaactc
tccgaaaacacaattatcattggtgtcgtacgcaggacggatagagaagagtcctctgtg
atgcccctcattgctgctggctttacaaggaggtatgtggaaaaccccagcctcatggcc
tgttacaacgaactgctccagctggagttcggagaggtgcggtcccagctgaaactcagg
gcttgtaactcaatattcactgcactggagaaaagtcaagaagcagttgaaattacaagt
gaagaccgcgttatacagtatgcaaatcctgcgtttgaaacaaccatgggctatcaagca
ggcgaactaataggcaaggagttagcggaagtgcctgtaaatgaaaaaaaggctgagttg
ctcgataccataaattcatgcatcaggataggcaaggagtggcaaggaatttaccatgcc
aaaaagaaaaatggagacaatgtacaacagaacgtgaagatagtacctgtcgtcggacag
ggaggaaaaattagacactatgtgtccattatcagagtgtgcaatggcaacaataaggcc
gagaaaagaactgaaagtgttcagtctgaccctcacacagataatcagtcaggcaaacac
aaagacagaaggaaaagctcgctcgatgtcagagctgttgcctctcgagcaagtgaagtc
agcagccagagacggcactcctccatggcccggatacattccatgacgatcgaggcgccc
atcaccaaggtaatcaacattatcaacgccgcccaggaaagcagccccatgcctgtgaca
gaagccttagaccgtgtgctggagattctgagaaccactgaattgtattcgccacagttc
ggtgctaaggacgatgatcctcatgccaatgaccttgttggaggcttaatgtctgatggt
ttgcgaagactatccgggaatgaatatgttctttcaacaaaaagcctgcagcaggtgccc
ggcagtgttgtcacccccatctcccttcacgacgtccctccccggatagctcgggctatg
gaaaatgaagagtactgggactttgatatttttgaactggaggccgccacacataaaagg
cctttgatctatcttggtctcaaaatgtttgcgcgctttggaatctgtgaattcttgaac
tgctctgaggcgacgctgagatcgtggctgcaaattattgaagccaattaccattcttgt
aacccctaccacaattccacacactctgccgacgtgcttcatgccactgcctatttcctc
tgcaaagagaggataaagcaaacgttagatccggttgacgaggtcgccgccctcattgca
gccaccatccacgacgtggaccaccccgggaggaccaactccttcctgtgcaatgccggc
agcgagctggccatcctgtacaacgacactgccgtgctggagagccaccacgcggccctg
gccttccagctgaccacccgcgatgacaaatgcaatatcttcaaaaacatggagaggaat
gactatcggacgctgcgccagggtattatcgatatggtcttggccacggaaatgacaaaa
cacttcgagcacgtcaacaaatttgtcaacagcatcaacaagcccctggcggcactagaa
gaaaacgaggaaacgaataaagacgaagaagccataaacactatgctccggactccagag
aaccggactctgattaaacggatgctcatcaagtgtgcggacgtgtccaatccctgccga
ccgctggagcagtgcatcgagtgggccgcacgcatatcagaagaatatttttctcagacg
gatgaggagaagcagcaggacttgcccgtggtgatgccggtttttgacagaaacacctgc
agcatccccaaatcccagatctctttcattgactacttcatcacggacatgtttgatgcc
tgggacgcctttgtcgacctgcctgagctaatgcagcatcttgacaacaacttcaaatac
tggaaaggactggacgagatgcagctgcggagcctccggccgccccctgaatag
DBGET
integrated database retrieval system
