Puma concolor (puma): 112860213
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Entry
112860213 CDS
T08890
Symbol
SDHA
Name
(RefSeq) succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial isoform X1
KO
K00234
succinate dehydrogenase (ubiquinone) flavoprotein subunit [EC:
1.3.5.1
]
Organism
pcoo
Puma concolor (puma)
Pathway
pcoo00020
Citrate cycle (TCA cycle)
pcoo00190
Oxidative phosphorylation
pcoo01100
Metabolic pathways
pcoo01200
Carbon metabolism
pcoo04714
Thermogenesis
pcoo04932
Non-alcoholic fatty liver disease
pcoo05010
Alzheimer disease
pcoo05012
Parkinson disease
pcoo05014
Amyotrophic lateral sclerosis
pcoo05016
Huntington disease
pcoo05020
Prion disease
pcoo05022
Pathways of neurodegeneration - multiple diseases
pcoo05208
Chemical carcinogenesis - reactive oxygen species
pcoo05415
Diabetic cardiomyopathy
Module
pcoo_M00009
Citrate cycle (TCA cycle, Krebs cycle)
pcoo_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
pcoo_M00148
Succinate dehydrogenase (ubiquinone)
Brite
KEGG Orthology (KO) [BR:
pcoo00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
112860213 (SDHA)
09102 Energy metabolism
00190 Oxidative phosphorylation
112860213 (SDHA)
09150 Organismal Systems
09159 Environmental adaptation
04714 Thermogenesis
112860213 (SDHA)
09160 Human Diseases
09161 Cancer: overview
05208 Chemical carcinogenesis - reactive oxygen species
112860213 (SDHA)
09164 Neurodegenerative disease
05010 Alzheimer disease
112860213 (SDHA)
05012 Parkinson disease
112860213 (SDHA)
05014 Amyotrophic lateral sclerosis
112860213 (SDHA)
05016 Huntington disease
112860213 (SDHA)
05020 Prion disease
112860213 (SDHA)
05022 Pathways of neurodegeneration - multiple diseases
112860213 (SDHA)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
112860213 (SDHA)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
112860213 (SDHA)
Enzymes [BR:
pcoo01000
]
1. Oxidoreductases
1.3 Acting on the CH-CH group of donors
1.3.5 With a quinone or related compound as acceptor
1.3.5.1 succinate dehydrogenase
112860213 (SDHA)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
FAD_binding_2
Succ_DH_flav_C
Thi4
Pyr_redox_2
GIDA
DAO
FAD_binding_3
HI0933_like
Motif
Other DBs
NCBI-GeneID:
112860213
NCBI-ProteinID:
XP_025779225
UniProt:
A0A6P6HTU7
LinkDB
All DBs
Position
Unknown
AA seq
655 aa
AA seq
DB search
MSGVRVVSRLLGARRLALTRAQWPATWQAGTCGFHFTIDGNKRSSAKVSDSISTQYPVVD
HEFDAVVVGAGGAGLRAAFGLSEAGFNTACVTKLFPTRSHTVAAQGGINAALGNMEEDNW
RWHFYDTVKGSDWLGDQDAIHYMTEQAPASVVELENYGMPFSRTEDGRIYQRAFGGQSLK
FGKGGQAHRCCCVADRTGHSLLHTLYGRSLRYDTSYFVEYFALDLLMENGECRGVIALCI
EDGSIHRIRAKNTVVATGGYGRTYFSCTSAHTSTGDGTAMVTRAGLPCQDLEFVQFHPTE
GCRGEGGILINSQGERFMERYAPVAKDLASRDVVSRSMTLEIREGRGCGPEKDHVYLQLH
HLPPEQLAIRLPGISETAMIFAGVDVTKEPIPVLPTVHYNMGGIPTNYKGQVLRHVNGQD
QIVPGLYACGEAACASVHGANRLGANSLLDLVVFGRACALSIAESCRPGDKVPPIKPNAG
EESVMNLDKLRFADGTLRTSELRLNMQKSMQNHAAVFRVGSVLQEGCEKISQLYGDLKHL
KTFDRGMVWNTDLVETLELQNLMLCALQTIYGAEARKESRGAHAREDYKERIDEYDYSKP
IQGQQKKPFEEHWRKHTLSYVDIKTGKVSLEYRPVIDRTLNEADCATVPPAIRSY
NT seq
1968 nt
NT seq
+upstream
nt +downstream
nt
atgtcgggggtccgggtggtgtcgcggctgctgggcgcccggcgcctggcactgactagg
gcgcagtggcccgcgacatggcaggcaggcacctgcggttttcacttcactattgatggg
aataagaggtcttcagctaaagtttcagattcaatttctacgcaatacccggtagtggac
catgaatttgacgcggtggtggtaggcgctggaggggcgggcttgcgagctgcgtttggc
ctttccgaggcagggtttaacacggcctgcgtcacaaagctctttcctacgagatcacac
accgttgcagcccagggagggatcaatgctgctctggggaacatggaggaggacaactgg
aggtggcacttctacgacactgtgaaaggctccgactggctgggggaccaggatgccatc
cactacatgacagagcaggcccctgcttccgtggtagagctggagaattatggcatgcca
ttcagcagaactgaagatgggaggatctaccagcgcgcttttggtggacagagcctcaag
tttgggaaaggcgggcaggcccatcggtgctgctgtgtggctgaccgcactggccactcg
ctgctgcacacgttgtatggaaggtctctgcgatatgataccagctattttgtagagtat
tttgccttggatctcctgatggaaaatggagaatgtcgtggtgttattgcgctgtgcata
gaagacgggtccatccatcgcataagagcaaagaacactgttgtagctactggaggctac
gggcgcacctacttcagctgcacatctgcccacaccagtaccggtgacggcaccgccatg
gtcaccagggcaggccttccctgccaggacttggagttcgttcagtttcaccccacagaa
gggtgccgtggagagggaggcattctcattaacagtcaaggcgaaagattcatggagcga
tatgccccggttgcaaaggacctggcatccagagacgtcgtgtctcggtccatgactctg
gaaatacgtgaaggaagaggctgtggccctgaaaaagatcacgtctacctgcagttgcac
cacctacccccagagcagctggccatacggctgcctggcatttcagagacggccatgatc
ttcgcaggtgtagatgtcaccaaggagcccatccccgtccttcccaccgtgcattataac
atgggcggcattcccaccaactacaaggggcaggttctgaggcatgtgaatggccaggat
cagatcgtgcccggcctgtatgcctgtggggaggctgcctgcgcctccgtgcatggtgcc
aaccgtcttggggcaaactcactcttggatctggttgtctttggtcgggcgtgtgccctg
agtatcgcggagtcctgcagacccggagataaagttcctccaattaaaccaaatgctgga
gaagagtctgtcatgaatcttgataagttgaggtttgctgatggaaccctaagaacatca
gaactacgactcaacatgcagaagtcgatgcaaaatcatgccgcagtgttccgtgtggga
agtgtgttacaggaaggttgtgagaaaatcagccagctctatggagacctaaaacatctg
aagacatttgaccgaggaatggtctggaacaccgacctggtggagaccctagagctgcag
aacctgatgctttgtgcacttcagaccatttatggagcagaggctcggaaggagtcacgt
ggtgctcatgccagggaagattataaggagcggattgacgagtatgattactccaagccc
atccaggggcagcagaagaagccatttgaggaacactggaggaagcacaccctttcctat
gtcgacatcaagactgggaaggtctccttggagtacagacccgtcattgacagaactttg
aatgaggcagactgtgccacagtccctccagccattcgctcctactga
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integrated database retrieval system
