Puma concolor (puma): 112860216
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Entry
112860216 CDS
T08890
Symbol
APC
Name
(RefSeq) adenomatous polyposis coli protein isoform X1
KO
K02085
adenomatosis polyposis coli protein
Organism
pcoo
Puma concolor (puma)
Pathway
pcoo04310
Wnt signaling pathway
pcoo04390
Hippo signaling pathway
pcoo04550
Signaling pathways regulating pluripotency of stem cells
pcoo04810
Regulation of actin cytoskeleton
pcoo04934
Cushing syndrome
pcoo05010
Alzheimer disease
pcoo05022
Pathways of neurodegeneration - multiple diseases
pcoo05165
Human papillomavirus infection
pcoo05200
Pathways in cancer
pcoo05206
MicroRNAs in cancer
pcoo05210
Colorectal cancer
pcoo05213
Endometrial cancer
pcoo05217
Basal cell carcinoma
pcoo05224
Breast cancer
pcoo05225
Hepatocellular carcinoma
pcoo05226
Gastric cancer
Brite
KEGG Orthology (KO) [BR:
pcoo00001
]
09130 Environmental Information Processing
09132 Signal transduction
04310 Wnt signaling pathway
112860216 (APC)
04390 Hippo signaling pathway
112860216 (APC)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
112860216 (APC)
09142 Cell motility
04810 Regulation of actin cytoskeleton
112860216 (APC)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
112860216 (APC)
05206 MicroRNAs in cancer
112860216 (APC)
09162 Cancer: specific types
05210 Colorectal cancer
112860216 (APC)
05225 Hepatocellular carcinoma
112860216 (APC)
05226 Gastric cancer
112860216 (APC)
05217 Basal cell carcinoma
112860216 (APC)
05213 Endometrial cancer
112860216 (APC)
05224 Breast cancer
112860216 (APC)
09172 Infectious disease: viral
05165 Human papillomavirus infection
112860216 (APC)
09164 Neurodegenerative disease
05010 Alzheimer disease
112860216 (APC)
05022 Pathways of neurodegeneration - multiple diseases
112860216 (APC)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
112860216 (APC)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
pcoo01009
]
112860216 (APC)
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
pcoo03036
]
112860216 (APC)
09183 Protein families: signaling and cellular processes
04812 Cytoskeleton proteins [BR:
pcoo04812
]
112860216 (APC)
Protein phosphatases and associated proteins [BR:
pcoo01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
112860216 (APC)
Chromosome and associated proteins [BR:
pcoo03036
]
Eukaryotic type
Centrosome formation proteins
Other centrosome associated proteins
112860216 (APC)
Cytoskeleton proteins [BR:
pcoo04812
]
Eukaryotic cytoskeleton proteins
Microtubules
Tubulin-binding proteins
EB / APC
112860216 (APC)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Arm_APC_u3
APC_basic
EB1_binding
APC_r
APC_u5
APC_u14
APC_rep
APC_u15
APC_u9
SAMP
Arm
APC_u13
APC_15aa
Suppressor_APC
ARM_ARMC5
ZER1-like_2nd
Sec7-like_HUS
Motif
Other DBs
NCBI-GeneID:
112860216
NCBI-ProteinID:
XP_025779235
UniProt:
A0A6P6HTV6
LinkDB
All DBs
Position
Unknown
AA seq
2872 aa
AA seq
DB search
MYACLGSGPVAVLPASAPPSTLGSWSSGGGRVPQERKRPGGVRTSGRGANVWQEVLKQLQ
GSIEDEAMASSGQIDLLERLKELNLDSSNFPGVKLRSKMSLRSYGSREGSVSSRSGECSP
VPMGSFPKRGFVNGSRENTGYLEELEKERSLLLADLDKEEKEKDWYYAQLQNLTKRIDSL
PLTENFSLQTDMTRRQLEYEARQIRVAMEEQLGTCQDMEKRAQRRVTRIQQIEKDILRIR
QLLQSQATEAERSSQSKHEAGSHEAERQNEGQGVAEINMATPGSGQGSAARMDHETASVL
SSSSTHSAPRRLTSHLGTKVEMVYSLLSMLGTHDKDDMSRTLLAMSSSQDSCISMRQSGC
LPLLIQLLHGNDKDSVLLGNSRGSKEARARASAALHNIIHSQPDDKRGRREIRVLHLLEQ
IRAYCETCWEWQEAHEQGMDQDKNPMPAPVEHQICPAVCVLMKLSFDEEHRHAMNELGRK
ATRGISSQELGQGLAGGLQAIAELLQVDCEMYGLTNDHYSITLRRYAGMALTNLTFGDVA
NKATLCSMKGCMRALVAQLKSESEDLQQVIASVLRNLSWRADVNSKKTLREVGSVKALME
CALEVKKESTLKSVLSALWNLSAHCTENKADICAVDGALAFLVGTLTYRSQTNTLAIIES
GGGILRNVSSLIATNEDHRQILRENNCLQTLLQHLKSHSLTIVSNACGTLWNLSARNPKD
QEALWDMGAVSMLKNLIHSKHKMIAMGSAAALRNLMANRPAKYKDANIMSPGSSLPSLHV
RKQKALEAELDAQHLSETFDNIDNLSPKASHRSKQRHKPNLYGDYVFDTNRHDDNRSDNF
NTGNMTVLSPYLNTTVLPSSSSSRGSLDSSRSEKDRSLERERGISLGNYHPATENPGTSS
KRGLQISTTAAQIAKVMEEVSAIHTSQEDRSSGSTGELHCGTDERNALRRSSTAHTHANT
YNFTKSENSNRTCPMPYAKLEYKRSSNDSLNSVSSSDGYGKRGQMKPSIESYSEDDESKF
CSYGQYPADLAHKIHSANHMDDNDGELDTPINYSLKYSDEQLNSGRQSPSQNERWARPKH
IIEDEIKQSEQRQSRSQSTTYPVYTESTDDKHLKFQPHFGQQECVSPYRSRGANGSETNR
VSSNHGINQNVNQSLCQEDDYEDDKPTNYSERYSEEEQHEEEERPTNYSIKYNEEKHHVD
QPIDYSLKYATDIPASQKPSFSFSKSSSGQSTKTEHISSSSENTSTPSSNAKRQNQHHPS
STQSRNGQTPKATSCKVPSINQETIQTYCVEDTPICFSRCSSLSSLSSAEDEIGCDQTTQ
ETDSANTLQIAEIKENSGTRSTEESVSEVPTVSQHIRTKSSRLQASGLSAESTRHKAVEF
SSGAKSPSKSGAQTPKSPPEHYVQETPLMFSRCTSVSSLDSFESRSIASSVQSEPCSGMV
SGIISPSDLPDSPGQTMPPSRSKTPPPPPPPQTVQSKREVPKNKAPTAEKRESGPKQAAV
NAAVQRVQVLPDADTLLHFATESTPDGFSCSSSLSALSLDEPFIQKDVELRIMPPVQEND
NGNETESEQPEEANESQVKEAEKPTDSEKDLLDDSDDDDIEILEECIISAMPTKSSRKAK
KPAQTAPKLPPPVARKPSQLPVYKLLPSQNRLQAQKHVSFTPGDDMPRVYCVEGTPINFS
TATSLSDLTIESPPNELAAGEGVRAGAQSGEFEKRDTIPTEGRSTDEAQRVKTPSATISE
LDDNKTEEGDILAECINSAMPKGKSHKPFRVKKIMDQVQQASMSSSGANKNQLDGKKKKP
TSPVKPIPQNTEYRTRVRKNTDSKNNLNAERTFSDNKDSKKQNLKNNSKDFNDKLPNNED
RVRGSFTFDSPHHYTPIEGTPYCFSRNDSLSSLDFDDDDVDLSREKAELRKGKENKESEA
KVTSHTELTSSQQSANKTQAVTKHPINRGQSKPMLQKQSTFPQSSKDIPDRGAATDEKLQ
NFAIENTPVCFSRNSSLSSLSDIDQENNNNKEGEPVKETEAPDSQGEPSKPQASGYAPKS
FHVEDTPVCFSRNSSLSSLSIDSEDDLLQECISSAMPKKKKPSRLKGDNEKHSPRNMSGI
LAEDLTLDLKDIQRPDSEHGLSPDSENFDWKAIQEGANSIVSSLHQAAAAACLSRQASSD
SDSILSLKSGISLGSPFHLTPDQEEKPFTSNKGPRILKPGEKSTLETKKIESENKGIKGG
KKVYRSLITGKVRSNSEISSQIKQPLQTNMPSISRGRTMIHIPGVRNSSSSTSPVSKKGP
PLKTPASKSPSEGQPATTSPRGTKPSVKSELSPVTRQTSQPAGANKGSSRSGSRDSTPSR
PAQQPLSRPMQSPGRNSISPGRNGISPPNKLSQLPRTSSPSTASTKSSGSGKMSYTSPGR
QMSQQNLTKQTGLSKNGSSIPRSESASKGLNQMNNGNGSNKKVELSRMSSTKSSGSESDR
SERPVLVRQSTFIKEAPSPTLRRKLEESASFESLSPSSRPDSPTRSQAQTPVLSPSLPDM
SLSTHSSVQSGGWRKLPPNLSPTIEYNDGRPAKRHDIARSHSESPSRLPINRSGTWKREH
SKHSSSLPRVSTWRRTGSSSSILSASSESSEKAKSEDEKHVNSISGTKQTKENQVSTKGT
WRKIKENEISPTNSTSQTTSSGAANGAESKTLIYQMAPAVSKTEDVWVRIEDCPINNPRS
GRSPTGNTPPVIDTVSEKGNPNAKDSKDNQGKQNVGNGSAPIRTMGLENRLNSFIQVDAP
DQKGTEAKPGQSNPVPVSETNESSIAERTPFSSSSSSKHSSPSGTVAARVTPFNYNPSPR
KSSADSTSARPSQIPTPVNNNTKKRDSKTDSTESSGTQSPKRHSGSYLVTSV
NT seq
8619 nt
NT seq
+upstream
nt +downstream
nt
atgtacgcctgtctgggctcgggtccggtcgccgttttgcctgcttctgcaccaccctct
accctcgggtcctggagctccggcggcggccgtgtcccgcaggagaggaagcgcccaggc
ggcgtccgtacttctggccgcggggcgaacgtctggcaggaagtacttaaacagctacaa
ggaagtattgaagatgaagctatggcttcttctggacagattgatttattagagcgtctc
aaagaacttaatttagatagcagtaatttccctggagtgaaactacgctcaaaaatgtcc
ctccgttcttatggaagccgcgaaggatctgtatctagtcgttcaggagagtgcagtcct
gttcctatgggttcgtttccaaaaagagggtttgtaaatggaagcagagaaaatactggt
tatttagaagaacttgagaaagaaagatcattacttcttgctgatcttgacaaagaagaa
aaggaaaaagactggtattatgctcaacttcagaatctcactaaaagaatagatagtctt
cctttaactgaaaatttttccttacaaacagatatgaccagaagacaattggaatatgaa
gcaaggcaaatcagagttgcaatggaagaacaactaggtacttgccaggatatggagaaa
agagcacagcgaagagtaaccagaattcaacaaatagagaaggacatacttcgtatacga
cagcttttacagtcccaagccacagaagcagagaggtcatctcagagcaagcatgaagcc
ggctcacatgaagctgagcggcagaatgaaggtcaaggagtggcagaaatcaacatggca
actcctggtagtggtcagggttcagctgcacgaatggatcatgaaacagccagtgttttg
agttctagtagcacacactctgctcctcgaaggctgacaagtcatctgggaaccaaggtg
gaaatggtgtattcattgttatcaatgcttggtactcatgataaggatgatatgtcgcga
actttgctagctatgtctagctcccaagacagctgtatatccatgcgacagtctggatgt
cttcctctcctcatccagcttttacatggcaatgacaaagactctgtgttgttgggaaat
tcccggggcagtaaagaggctcgggccagggccagtgcagcacttcacaacatcattcac
tcacagcctgatgacaagagaggcaggcgtgaaatccgagtccttcatcttttggaacag
atacgagcttactgtgaaacctgttgggagtggcaggaagcccatgaacaaggcatggac
caggacaaaaatccaatgccagctcctgttgaacatcagatctgtcctgctgtgtgtgtt
ctaatgaaactttcatttgatgaagaacatagacatgcaatgaatgaacttggtaggaag
gctacccggggcatttcatcacaggagctagggcaggggcttgcagggggactacaggcc
attgcagaattattgcaggtggattgtgaaatgtatgggctaactaatgaccactacagt
attacattaagacgatatgctggaatggctttgacaaacttgacttttggagatgtagcc
aacaaggctacactctgctctatgaaaggctgcatgagagcacttgtggcccaactaaaa
tctgaaagtgaagacttacagcaggttattgcaagtgttttgaggaatttgtcttggcga
gcagatgtaaatagtaaaaagacattgcgtgaagttggaagtgtgaaagcattaatggaa
tgtgctttggaagttaaaaaggaatcaaccctcaaaagcgtattgagtgccttatggaat
ttgtcagcacattgcactgagaataaagctgatatatgtgctgtagatggtgcgcttgca
tttctggttggcactctcacttaccgaagccagacaaatactttagccattattgaaagt
ggaggtggaatattacggaacgtgtccagcttgatagctacaaatgaggaccacaggcaa
atcctaagagagaacaactgcctgcaaaccttattacaacacttgaaatctcacagtttg
acaatagtcagtaatgcatgtggaaccttgtggaatctctcagcaagaaatcctaaagac
caggaagcattatgggacatgggggcagtcagcatgctcaagaacctcattcattcaaag
cacaaaatgattgctatgggaagcgctgcagctttaaggaatctcatggcaaatagacct
gcaaagtataaggatgccaatataatgtctcctggttcaagcttgccatctcttcatgtc
aggaaacaaaaagccctagaagcagaattagatgctcagcatttatcagaaacttttgac
aatattgacaatttaagtcccaaggcatctcatcgtagtaagcaacgacacaagccaaat
ctttatggtgactatgtttttgacaccaatcgacatgatgataatagatcagacaatttt
aatactggaaacatgactgtcctttcaccatatttaaatactacagtgttgcccagctcc
tcttcatcaagaggaagtttagacagttctcgttctgaaaaagatagaagtttggagaga
gaacgaggaattagcctaggcaactaccacccagcaacagaaaatccaggcacttcttca
aagcgaggtttgcagatttccaccactgcagcccagattgccaaagtcatggaagaagta
tcagccattcacacctcccaggaagacagaagttctgggtctaccggcgagttacattgt
gggacagatgagaggaatgcactaagaagaagctccactgcccacacacatgcaaacact
tacaacttcactaagtcagaaaattcaaataggacatgtcctatgccttatgccaaattg
gaatataagagatcttcaaatgatagtttaaatagtgtcagtagtagtgatggttatggt
aaaagaggtcagatgaagccttccattgaatcctattctgaagatgatgaaagtaaattt
tgcagctatggtcagtatccagctgacctagcccataaaatacacagcgcaaatcatatg
gatgataatgatggagaactagatacaccaataaattatagtcttaaatactcagatgag
cagttgaactccggaaggcaaagcccttcacagaatgaaagatgggcaagacccaaacat
ataatagaagatgaaataaaacagagtgagcaaagacaatcaagaagtcaaagcacaact
taccccgtatatactgagagcactgatgataaacatctcaagtttcagccacattttgga
cagcaggaatgtgtttccccatataggtcaagaggagccaatggttcagaaacaaatcga
gtaagttccaatcatggaattaatcaaaatgtaaaccagtctttgtgtcaggaagatgac
tatgaagatgataagccaaccaactatagtgaacgttactccgaggaagagcagcatgaa
gaagaagagagaccaacaaattatagcataaagtataatgaagagaaacatcatgtggat
caacctatcgattatagtttaaaatatgccacagacattcctgcctcacagaaaccatca
ttttcattctcaaagagttcatctggacaaagcactaaaactgaacacatctcttcaagc
agtgagaatacatccacaccttcatctaatgccaagaggcagaatcagcaccatccaagt
tccacacaaagcagaaatggtcagaccccaaaagccacctcctgcaaagttccctctatc
aaccaagaaacaatacagacttactgtgtagaggatactccaatatgtttctcacgttgc
agttcactatcatctttgtcatcggccgaagatgaaataggatgtgatcagacaacacag
gaaacagattctgctaatactctacaaatagcagaaataaaagaaaacagtgggactaga
tcaacagaagagtctgtgagtgaagttccaacagtgtcacagcacattagaaccaaatcc
agcagacttcaggcttctggtttatctgcagaatcgaccaggcataaagctgttgaattt
tcttcaggggctaaatctccatcaaaaagtggtgctcagacacctaaaagtccaccagag
cactacgttcaggagactccactcatgtttagcagatgcacttctgtcagttcacttgat
agttttgagagtcgttcgattgccagctccgttcagagtgaaccctgcagtggaatggta
agtggcattataagccccagtgaccttccagatagccctggacaaaccatgccaccaagc
agaagtaaaacccctcctcctcctcctcctcctcagacagttcagagtaagcgagaggta
cctaaaaacaaagcccctactgcggaaaagagagagagtggaccgaagcaagctgctgta
aatgctgcagtacagagagtccaggtgcttccagatgctgatactctcttacattttgcc
acagaaagtactccagatggattttcttgttcatctagcctgagtgctctgagcctcgat
gagccatttatacagaaagatgtggaattaagaataatgcctccagttcaggaaaatgac
aatgggaatgaaaccgaatctgagcagcctgaagaagcaaatgaaagccaggtaaaagaa
gcagaaaaacctactgattctgaaaaagatctgttagatgactcagatgatgatgatatt
gaaatattagaagaatgtattatttctgccatgccaacaaaatcttcacgtaaagccaaa
aaaccagcccagactgctccaaaattacctccacctgtggcaaggaaaccaagtcaactc
cctgtgtataaacttcttccatcacaaaacaggttacaggcacaaaaacatgttagtttt
acaccaggagatgatatgccacgggtgtattgtgtagaagggacacctataaacttttcc
acagctacatctttaagtgatctaacaatagaatctcctccaaatgagttagctgctgga
gaaggggttagagcaggagcacagtccggtgaatttgaaaaacgagataccattcctaca
gaaggcagaagtacagatgaggctcaaagagtaaaaaccccatctgcaactatatctgaa
ctggatgacaataaaacagaagaaggtgatattcttgcagaatgcattaactctgctatg
cccaaaggaaaaagtcacaagcctttccgtgtgaagaagataatggaccaggtccaacaa
gcatctatgtcttcatctggagctaacaaaaatcagttagatggtaagaaaaagaaacct
acttcaccagtaaaacctataccacaaaatactgaatataggacacgtgtaagaaaaaac
acagactcaaaaaataatttaaatgctgaaagaactttctcagacaacaaagattcaaag
aaacagaacttgaaaaataattccaaggacttcaatgataagctaccaaataatgaagat
cgagtcagaggaagttttacttttgattcacctcatcattacactcccattgaaggaact
ccatactgtttttcacgaaatgattctttgagttctctagattttgatgatgatgatgtt
gacctttctagagaaaaggctgaattaagaaaggggaaagaaaataaagaatcagaagct
aaagttaccagccacacagaactaacctctagccaacaatcagctaataagacacaagct
gttacaaaacatccaataaatcgaggtcagtctaaacccatgctgcagaagcaatccact
tttccacagtcatccaaagacataccagacaggggagcagcaactgatgagaaattacaa
aattttgctattgaaaatactccggtgtgcttttctcgaaattcctctttaagttctctt
agtgacattgatcaagaaaacaacaataacaaagaaggtgaacctgtcaaagagacagag
gcccctgactcacagggagaacccagtaaacctcaggcatcaggttatgctcctaaatca
tttcatgttgaagatacccctgtttgtttctcacgaaatagttctctcagttctcttagt
attgattctgaagatgacctgttgcaggaatgtataagttctgcaatgccaaaaaagaaa
aagccttcaagactcaagggtgataatgaaaagcatagtcccagaaatatgagtggcata
ttggcagaagatttgacacttgatttgaaagatatacagagaccagattcagaacatggt
ttatccccagattcagaaaattttgattggaaagctattcaggaaggtgcaaattccata
gtaagtagtttacatcaagctgctgctgctgcatgtttatctagacaggcatcatctgac
tcagactccatcctttcactgaaatcagggatctccctgggatcaccatttcatcttaca
cctgatcaagaggaaaaaccctttacaagtaataagggcccacgaattctaaaacctggg
gagaagagtacattggaaactaaaaagatagaatctgaaaataaaggaatcaaaggagga
aaaaaagtttatagaagtttaattaccggaaaagttcgttctaattcagaaatttcaagc
caaataaaacagcctcttcaaacaaacatgccttcaatctctcggggcaggacaatgatt
catattccaggagttcgaaatagctcttcaagtacaagtccggtttctaaaaaaggccca
ccccttaagactccagcctccaaaagccctagtgaaggtcagccagccaccacttctcct
agaggaaccaagccatctgtgaagtcagaattaagccctgttaccaggcagacatcccaa
ccagctggagcaaataaagggtcttctagatcaggatctagagattccactccttcaaga
cctgcccaacaaccattaagtagacccatgcagtctccggggcggaactcaatttctcct
ggtcgaaatggaataagccctcctaataaattatcccagttgccaaggacttcatcccct
agtactgcttcaactaagtcctcaggttctggaaagatgtcatacacatctccaggcaga
cagatgagccagcagaaccttaccaagcaaacgggtttatccaagaatggcagcagtatc
ccaagaagtgagtctgcctccaaaggactaaatcagatgaataatgggaatggatccaat
aaaaaggtagaactttctagaatgtcctcaactaaatcaagtggaagtgaatctgatagg
tcagagagacccgtattagtacgccagtcaactttcatcaaagaagctccaagcccaacc
ctaaggagaaaattggaggaatctgcttcatttgaatctctttctccatcttctagacca
gattctcccactaggtcccaggcacagactccagttttaagtccttcccttcctgatatg
tctctgtccacacattcatctgttcagtctggtggatggcgaaaactcccacctaatctc
agtcccaccatagagtataatgatggaagaccagcaaagcgccatgatatagcacgctcc
cattctgaaagtccttctagacttccaattaataggtcaggaacctggaaacgtgagcac
agcaaacattcatcctcccttccacgagtaagcacttggagaagaactggaagttcatcc
tcaattctttctgcttcatcagaatccagtgaaaaagcaaaaagtgaagatgaaaaacat
gtgaactctatttcaggaaccaaacaaactaaagaaaaccaagtatccacaaaaggaaca
tggagaaaaataaaagaaaatgagatttctcccacaaatagtacctctcagaccacttcc
tcaggtgctgcaaatggtgctgaatcaaagactctgatttatcaaatggcacctgctgtt
tctaaaacagaggatgtttgggtgagaattgaggactgtcccatcaacaaccctagatct
ggaagatccccaacaggaaatactccccctgtgattgacactgtttcagaaaagggaaat
ccaaatgctaaagattcaaaagataatcagggaaaacaaaatgtgggtaacggcagtgct
cccatacgcaccatgggtttggaaaaccgcctgaactcctttattcaggtagatgcccca
gaccaaaaaggaactgaggctaaaccgggacaaagtaaccctgtccctgtgtcagagact
aatgaaagttccatagctgagcgtacccctttcagttctagcagttcaagcaagcacagt
tcacctagtgggactgttgctgccagagtgactccgtttaactacaatccaagccctagg
aaaagcagcgcagatagcacttcagctcggccatctcagatcccgacaccagtgaacaac
aacacgaagaaacgagattcaaaaactgacagcacagaatccagtggaactcaaagtcct
aagcgccattctgggtcttaccttgtgacatctgtttaa
DBGET
integrated database retrieval system
