Puma concolor (puma): 112860252 Help Entry 112860252         CDS       T08890                                  Symbol ITGA2 Name (RefSeq) integrin alpha-2   KO K06481   integrin alpha 2 Organism pcoo  Puma concolor (puma) Pathway pcoo03271   Virion - Rotavirus pcoo04145   Phagosome pcoo04151   PI3K-Akt signaling pathway pcoo04510   Focal adhesion pcoo04512   ECM-receptor interaction pcoo04611   Platelet activation pcoo04640   Hematopoietic cell lineage pcoo04810   Regulation of actin cytoskeleton pcoo04820   Cytoskeleton in muscle cells pcoo05165   Human papillomavirus infection pcoo05200   Pathways in cancer pcoo05205   Proteoglycans in cancer pcoo05222   Small cell lung cancer pcoo05410   Hypertrophic cardiomyopathy pcoo05412   Arrhythmogenic right ventricular cardiomyopathy pcoo05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:pcoo00001]  09120 Genetic Information Processing   09125 Information processing in viruses    03271 Virion - Rotavirus     112860252 (ITGA2)  09130 Environmental Information Processing   09132 Signal transduction    04151 PI3K-Akt signaling pathway     112860252 (ITGA2)   09133 Signaling molecules and interaction    04512 ECM-receptor interaction     112860252 (ITGA2)  09140 Cellular Processes   09141 Transport and catabolism    04145 Phagosome     112860252 (ITGA2)   09144 Cellular community - eukaryotes    04510 Focal adhesion     112860252 (ITGA2)   09142 Cell motility    04820 Cytoskeleton in muscle cells     112860252 (ITGA2)    04810 Regulation of actin cytoskeleton     112860252 (ITGA2)  09150 Organismal Systems   09151 Immune system    04640 Hematopoietic cell lineage     112860252 (ITGA2)    04611 Platelet activation     112860252 (ITGA2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     112860252 (ITGA2)    05205 Proteoglycans in cancer     112860252 (ITGA2)   09162 Cancer: specific types    05222 Small cell lung cancer     112860252 (ITGA2)   09172 Infectious disease: viral    05165 Human papillomavirus infection     112860252 (ITGA2)   09166 Cardiovascular disease    05410 Hypertrophic cardiomyopathy     112860252 (ITGA2)    05412 Arrhythmogenic right ventricular cardiomyopathy     112860252 (ITGA2)    05414 Dilated cardiomyopathy     112860252 (ITGA2)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:pcoo04147]     112860252 (ITGA2)    04515 Cell adhesion molecules [BR:pcoo04515]     112860252 (ITGA2)    04090 CD molecules [BR:pcoo04090]     112860252 (ITGA2) Exosome [BR:pcoo04147]  Exosomal proteins   Exosomal proteins of colorectal cancer cells    112860252 (ITGA2)   Exosomal proteins of bladder cancer cells    112860252 (ITGA2) Cell adhesion molecules [BR:pcoo04515]  Integrins   Integrin alpha subunits    112860252 (ITGA2) CD molecules [BR:pcoo04090]  Proteins   112860252 (ITGA2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  VWA FG-GAP Integrin_A_Ig_2 Integrin_A_Ig_3 VWA_2 FG-GAP_2 FG-GAP_3 ITGAX-like_Ig_3 HisK_sensor Integrin_alpha PND Motif Other DBs NCBI-GeneID:  112860252 NCBI-ProteinID:  XP_025779286 UniProt:  A0A6P6HUZ9 LinkDB All DBs Position Unknown AA seq 1177 aa AA seqDB search MRPGWTGGAPLLVLVLSQGILNCMAYNVGLLEAKIFSGPSSEQFGYAVQQFINPKGNWLL VGSPWSGFPENRMGDVYKCPVDLSTATCEKLNLQTATSIPNVTEMKTNMSLGLTLTRNVG TGGFLTCGPLWAQQCGSQYYATGVCSDISPNFQLLASFAPAVQTCPSLIDVVVVCDESNS IYPWDAVKNFLEKFVQGLDIGPTKTQVGLIQYANIPRVVFNLNTFKTKAAMIEATSRTYQ FGGDLTNTFKAIQYAKDFAYAAAAGGRPGATKVMVVVTDGESHDGSMLKAVIDECNNYNI LRFGIAVLGYLNRNALDTKNLIKEIKAIASIPTERYFFNVSDEAALLEKAGTLGEQIFSI EGTIQGGDNFQMEMSQVGFSADYSPQKDILMLGAVGAYGWSGTVVQQTSHGHMIFPKQAF DQILQDKNHSSYLGYSVAAISTGKDVHFVAGAPRANYTGQIVLYSVDENGNVTVIQAHRG DQIGSYFGSVLCSVDVNKDTVTDVLLVGAPMYMNDLKKEEGRVYLFTITKGVLNWHQFLE GPKGVENARFGSAIAALSDINMDGFNDVIVGSPLENQNSGAVYIYNGHEGTIRMKYSQKI LGSDGAFRSHLQYFGRSLDGYSDLNGDSITDVSIGAFGQVVQLWSQSIADVSVDASFTPE KITLVNKNADIKLKLCFSAKFRPTKQNSQVAIIYNITIDADLYSSRVTSRGLFKENNERC LQKNMIVSQTQSCSEYIIHIQKPSDVVSSLDLCVNVSLENPGTSPALEAYSEKAKVFSIP FYKECGDDGVCISDLVLDVQQLSAAQDQPFIVSNQNKRLTFLVTLKNKRESAYNTGIVVD FSENLFFASWTVPVDGTEVVCQIASSQKSVTCDVGYPALKTEQQVTFMINFDFNLQNLQN QASVSFQALSESSEENKADNLVNFKIPLLYDAEIHITRSTNINFYEVSSDGNVPSVVHSF EDIGPKFVFSVKVTTGSVPVSMASVIIHIPQYTKGKNPLMYVTGVHTDQAGDISCNAEIN PLKIGPTASSVSFKNENFRHIKELNCRSATCSNVTCWLKDLQVKGEYFLNVSTRIWNGTF AASTFQTVQLTASAEINTYNPQIYVIEENTVTIPITIMKPHEKAEVPTGVIVGSVIAGIV LLLALVAVLWKLGFFKRKYEKMSKTADEIDETTELNS NT seq 3534 nt NT seq  +upstreamnt  +downstreamnt atgcggccaggatggacagggggcgcgccgttgctggtgttagtgctcagtcaagggatt ttaaattgtatggcatacaatgttggtctcctagaagcaaagatattttccggtccttca agtgagcagtttggctatgctgtgcagcagtttataaatccaaaaggcaactggttactg gttggttcaccttggagtggttttcctgagaaccgaatgggagacgtgtataaatgtcct gttgatctgtccactgctacatgtgaaaaactgaatctgcaaactgccacaagcattccc aatgttaccgaaatgaaaaccaacatgagccttggcttgacactcacaaggaacgtagga accggaggatttctcacgtgtggtcccctgtgggcacagcaatgcggaagccagtattat gcaactggtgtttgttctgatatcagtcccaattttcagctcttggccagctttgcacct gcagttcagacctgcccttccctcatagatgttgtggttgtatgtgatgagtcaaacagt atttatccctgggatgcagtaaagaattttttggaaaaatttgtacaaggcctggatata ggccccacaaagacacaggtggggttaattcagtatgccaacataccaagagttgtattt aacctgaacactttcaaaaccaaagctgcaatgattgaagcaacatcccggacataccaa tttggtggagatctcacaaatacattcaaagcaattcaatatgcaaaagattttgcatat gcagcagctgctggaggacgaccaggtgctaccaaagtaatggtggttgtaactgatggt gaatcacatgatggttcaatgctgaaggccgtgattgatgaatgcaacaattacaatata ctgaggtttggcatagcggttcttgggtacttaaacagaaatgcccttgacaccaaaaat ttaataaaagaaattaaagcaattgccagtattccaacagaaagatattttttcaacgtg tctgatgaagcagctctactagaaaaggctgggacactaggagaacaaatttttagcatt gaaggtactattcaaggaggggacaacttccagatggaaatgtcacaagtgggattcagc gcagattactctcctcaaaaggatattctgatgctgggtgcagtaggagcttatggctgg agtggtaccgtggtccagcagacatctcatggacatatgatctttcctaaacaagccttt gaccaaattctgcaagataaaaatcacagttcatatttaggttactctgtggctgcaatt tctaccggaaaagatgttcactttgttgctggtgctcctcgggcaaattacactggccag atagtgctatacagtgttgacgagaatggcaatgtcaccgttattcaggctcaccgaggt gaccagattggctcctattttggtagcgtgctgtgttcagttgatgtgaataaagacacc gttacagatgtgctcttggtgggtgcaccgatgtacatgaatgacttaaagaaagaggaa ggaagagtctacctgtttactatcacaaagggcgttttgaattggcaccaatttcttgaa ggccctaagggtgttgaaaatgctcggtttggttcagcgattgcagctctttcagatatc aacatggatggttttaatgatgtaatagttggttcacctttggaaaatcagaactctgga gctgtgtacatctacaatggtcacgagggcaccattcgcatgaagtattcccagaaaatc ttgggatctgatggagcctttaggagccatctccagtactttgggagatctttggatggc tacagtgatttaaatggggattccatcactgatgtgtccattggtgcctttggacaagtg gttcagctctggtcacagagtatcgctgatgtatctgtggatgcttctttcacgccagaa aaaattactttggtcaacaagaatgctgacataaaactcaaactctgtttcagtgcaaag tttagacctactaagcaaaacagtcaagtggccattatatacaacatcacaattgatgca gacctatattcatccagagtaacctccagggggctatttaaagaaaataatgaaagatgc ctgcagaagaatatgatagtaagtcaaacacagagttgctctgagtacatcatccacata cagaagccctctgatgttgtcagctctttggatctgtgtgtcaatgtcagtctggaaaac cctggcaccagccctgccctcgaagcctactctgagaaggccaaggtcttcagtatccct ttctacaaggaatgtggggatgatggagtttgcatctctgatctagttctagatgtccaa cagctgtcagctgctcaagatcaaccctttattgtcagcaaccaaaacaaaaggttaaca tttttagtaacgctgaaaaacaaaagggaaagtgcctacaacactggaattgttgttgat ttttcagaaaacttgtttttcgcttcctggaccgtgccggttgatgggacagaagtcgta tgccagattgcttcatctcagaagtctgttacctgtgatgtaggctacccagctttaaag acagagcaacaggtgactttcatgattaactttgacttcaatcttcaaaaccttcagaat caggcatctgtcagtttccaagccttaagcgaaagctctgaagaaaacaaggcagataat ttggtcaatttcaaaatccctctgctgtatgacgccgaaattcacataacaagatccacc aacataaatttttatgaagtctcctcggatgggaatgttccttctgtcgtgcacagtttt gaagatattggtccaaagttcgtcttctctgttaaggtaacaacaggaagtgttccagtc agcatggcatccgtgatcatccacatccctcaatacaccaaaggaaagaacccgttgatg tatgtgactggggtgcacacagatcaggctggtgacatcagttgtaatgctgaaataaat ccactgaaaataggacccacagcttcttctgtatctttcaagaatgaaaatttccggcac ataaaagaattgaactgtagaagtgctacgtgcagcaatgttacctgctggctgaaagac cttcaggtcaaaggagagtacttccttaatgtgtctaccagaatttggaatggaactttt gcggcatcaactttccagacagtacagctgaccgcatctgcagaaataaacacctacaat cctcagatatatgtgatcgaagaaaacacagtcacgattcccattacgataatgaaaccc catgagaaagctgaagtaccaactggagttatagtaggaagtgtaattgctggaatcgtt ttgctattagctctggttgcagttttatggaagcttggcttcttcaaaagaaaatatgaa aaaatgtccaaaactgcggatgagattgacgagaccacagaactcaacagctga

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