Puma concolor (puma): 112862821 Help Entry 112862821         CDS       T08890                                  Symbol DNAH8 Name (RefSeq) dynein heavy chain 8, axonemal   KO K10408   dynein axonemal heavy chain Organism pcoo  Puma concolor (puma) Pathway pcoo04814   Motor proteins pcoo05014   Amyotrophic lateral sclerosis pcoo05016   Huntington disease pcoo05022   Pathways of neurodegeneration - multiple diseases Brite KEGG Orthology (KO) [BR:pcoo00001]  09140 Cellular Processes   09142 Cell motility    04814 Motor proteins     112862821 (DNAH8)  09160 Human Diseases   09164 Neurodegenerative disease    05014 Amyotrophic lateral sclerosis     112862821 (DNAH8)    05016 Huntington disease     112862821 (DNAH8)    05022 Pathways of neurodegeneration - multiple diseases     112862821 (DNAH8)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    03037 Cilium and associated proteins [BR:pcoo03037]     112862821 (DNAH8)    04812 Cytoskeleton proteins [BR:pcoo04812]     112862821 (DNAH8) Cilium and associated proteins [BR:pcoo03037]  Motile cilia and associated proteins   Dynein arm    112862821 (DNAH8) Cytoskeleton proteins [BR:pcoo04812]  Eukaryotic cytoskeleton proteins   Microtubules    Tubulin-binding proteins     Dyneins      112862821 (DNAH8) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  DHC_N1 AAA_6 Dynein_C DHC_N2 AAA_8 AAA_9 AAA_7 AAA_lid_11 MT Dynein_heavy AAA_5 Dynein_AAA_lid AAA_lid_1 DYN_lid AAA_16 Motif Other DBs NCBI-GeneID:  112862821 NCBI-ProteinID:  XP_025781833 UniProt:  A0A6P6I3M5 LinkDB All DBs Position Unknown AA seq 4515 aa AA seqDB search MSGIPNLQETLKERQARFREARENRKTKIDPSYKYIFEILAEKLGLDLVTIEELILDCPS LDAFAQFFMKDGCKTLKFLYQEGDVPGIECGRTIAGATKGAKMMRLYIDNAAPEKLKGLC IFFVRCHNDIAINVKNIHEEVLFTVLDASTGILPGIRNMLSSIFVPAILATNNWGALNQS KQGESEKHIFTETINRYLSFLDGARVSIEGTVKLKKVDNVDFSKLHTFEEVTAAASNSEM VRQLEDVLMTWYRQIEQVLIESEQMRKEADDSGPLTELEHWKRMSAKFNYIIEQIKGPSC KAVINVLNVAHSKLLKNWRDLDARITDTANESKDNVRYLYTLEKVCQPLYNYDLVSMAHG IQNLINAIRMIHGVSRYYNTSERMTSLFIKVTNQMVTACKAYITDGGTVHVWDQETPLVL KKIQDCIFLFKEYQTSFHKTRKQILESSGEKSFEVSEMYIFGKFEAFCKRLEKITEMITI VQTYSALSNSTIEGIDIMAIKFKSIYQGVKKKQYDILDPRRTEFDTDFSEFMTKINGLEI QIQAFMNSTFGKILSSQQALQLLQRFQKLNIPCLQLEINHTIERILQYYVAELEATKKLY HSQKDDPPLARNMPPIAGKILWVRQLYRRISEPINYFFKNSEILSSAEGKAVIRQYNKIS YVLVEFEVVYHTAWVREISQLQYALQATLFVRHPETGKLLVNFDPKILEVVRETKCMIKM KLDVPEEAKRLLKLENKLKADKLHLQGLLQYYDELCQEVPSVFVNLMTPRMKKVESVLRQ GLTILTWSSLTLESFFQEVDSVLDMFNQLLKKISDLCEMHIDTVLKEIAKTVLISLPESG ATKVEDMLTLNETYTKEWADILNHKSKHVEEAVKELILIFEAIYEVKDSGKTAKPLPEQR KHVAFGSETEEGENPDYETNILPQADFNDKEDEFKKECKEVYAFFSHQLLDSLQKATRLS LDTMKRRIFVSSQYGRRRSEDVISFIKTEVHLAIPNVVMVPSLDDIQQAINRMIQLTLEV SRGVAHWGQQPTRQVKPVVTSPSRTTDLMHLNTTKQAKKEEKPVEEVITARKLKNFYPGV AEHKDISKLVLLLSSSVNSLRKVAHEALQDFQKYKTLWTEDRDVKVKEFLANNPSLTETR SEILHFATFEQEIDELKPIIVVGALELHTGPMKLALSIEAKAWKMLLCRYLNEEYKKKMS DMIAFINEYLKKLSRPIRDLDDVRFAMEALACIRDNEIQMDMTLGPIEEAYAILNRFEVE VTKEESEAVDTLRYSFNRLQSKAVSVQDELVQVQPKFKSNLLEAVEVFREDVMNFAEAYE MEGPMVPNIPPQEASNRLQIFQANFDDLWRKFVTYSSGEQLFGLPVTDYEVLHKTRKELN LLQKLYGLYDTVMSNISGYYEILWGDVDIEKINAELQEFQNSWDICISAIKEKDIEAKLT QVIENWTNQNLSFAAFKGKGELLLKGTESGEIITLMEDSLMVLGSLLSNRYNAPFKKTIQ NWVYKLSTSSDIIEEWLVVQNLWVYLEAVFVGGDIAKQLPQEAKRFQNIDKSWIKIMQRA HENPNVISCCVGDETMGQLLPHLHEQLEVCQKSLTGYLEKKRLLFPRFFFVSDPVLLEIL GQASDSHTIQPHLPAVSDNINEVTFHAKDYDRILAVISREGEKIMLDNPVMAKGPVEIWL MDLLKMQMSSLHNIIRSAFYQISDSGFQLLPFLNHFPAQVGLLGIQMLWTHDSEEALHNA KDDRKIMQVTNQKFLDILNILISQTTHDLSKFDRVKFETLITIHVHQRDIFDDLVKMHIK SVTDFEWLKQSRFYFKEDLDQTVVSITDVDFIYQNEFLGCTDRLVITPLTDRCYITLAQA LGMNMGGAPAGPAGTGKTETTKDMGRCLGKYVVVFNCSDQMDFRGLGRIFKGLAQSGSWG CFDEFNRIELPVLSVAAQQIYIVLTARKERKKQFIFSDGDCVDLNPEFGIFLTMNPGYAG RQELPENLKIQFRTVAMMVPDRQIIMRVKLASCGFLENVVLAQKFYVLYKLCEEQLTKQV HYDFGLRNILSVLRTLGSQKRARPEDSELSTVMRGLRDMNLSKLVDEDEPLFLSLINDLF PGLQLDSSTYAELQAAVANQVQIEGLINHPPWNLKLVQLYETSLVRHGLMTLGPSGSGKT TVITILMKALTECGRPHREMRMNPKAITAPQMFGRLDTATNDWTDGIFSTLWRKTLKAKK GENIFLILDGPVDAIWIENLNSVLDDNKTLTLANGDRIPMAPNCKLLFEVHNIENASPAT VSRMGMVYISSSALSWRPILQAWLKKRTAQEASVFQTLYDKIFEDIYTFMKLNLNPKMQL LECNYIMQSLTLLEGLIPSKEEGGISCVEHLHKLFVFGLMWSLGALLELESREKLEAFLR SHGSKLDLPEIPKGTNQTMYEFYVTDYGDWEHWNKKLQPYYYPTDSIPEYSSILVPNVDN IRTNFLIDTIAKQYKAVLLTGEQGTAKTVMIKAYLKRYDPEVQLSKSLNFSSATEPVMFQ RTIESYVDKRMGSTYGPPGGRKMTVFIDDINMPVINEWGDQVTNEIVRQMMEMEGMYSLD KPGDFTTIVDVQLIAAMIHPGGGRNDIPQRLKRQFTVFNCTLPSNASIDKIFGLIGCGYF DPCRKFKPEICEMIGNLVSAGRVLWQWTKVKMLPTPSKFHYIFNLRDLSRIWQGMLTIKS EECDSISVLLSLFKHECNRVIADRFITSEDEQWFNIHLIHAIEENISPDVASYILPEPYF VDFLREMPEPTGDEPEDTVFEVPKVYELVPSFDFLSEKLQFYQRQFNEIIRGTSLDLVFF KDAMTHLIKISRIIRTSCGNALLVGVGGSGKQSLSRLASFIAGYQIFQITLTRSYNVNNL TEDLKGLYKVAGAEGKGITFIFTDNEIKDEAFLEYLNNLLSSGEISNLFARDEMDEITQG LISVMKKELPRHPPTFDNLYEYFISRSRKNLHVVLCFSPVGEKFRARSLKFPGLISGCTM DWFSRWPKEALIAVASYFLSGYGIVCSSDTKRQVVETMGLFHDMVSESCESYFQRYRRRA HVTPKSYLSFINGYKTIYAEKVKFINEQAERMNIGLDKLMEASESVAKLSQDLAVKEKEL AVASVKADEVLAEVTVSAQASAKVKNEVQEVKDKAQKIVDEIDSEKVKAETKLEAARPAL EEAEAALNTIKPNDIATVRKLAKPPHLIMRIMDCVLLLFQKKIDPVTMDPEKPCCKPSWG ESLKLMSATGFLWSLQQFPKDTINEETVELLQPYFNMDDYSLENAKKVCGNVAGLLSWTL AMATFYGVNREVLPLKANLAKQEGRLAVANAELGKAQELLDEKQAELDKVQAKFDAAMNE KMDLLNDADMCRKKMQAASTLIDGLSGEKVRWTQQSKEFKAQINRLVGDILLCTGFLSYL GPFNQIFRNYLLKDQWEIELRARKIPFTENLNLISMLVDPPTIGEWGLQGLPGDDLSIQN GIIVTKATRYPLLIDPQTQGKTWIKSKERENDLQVTSLNHKYFRTHLEDSLSLGRPLLIE DIREELDPALDNVLEKNFIKSGTTFKVKVGDKECDIMDTFKLYITTKLPNPAFTPEINAK TSVIDFTVTMKGLENQLLRRVILTEKQELESERVKLLEDVTFNKRKMKELEDNLLYKLSA TKGSLVDDESLIGVLRTTKQTASEVSEKLHVAAETEIKINTAQEEFRPAATRGSILYFLI TEMSMVNIMYQTSLAQFLKLFDQSMARSEKSPLPQKRITNIIEYLTYEVFTYSVRGLYEN HKFLFVLLMTLKIDLQRGTVKHREFQALIKGGAALDLKACPPKPFRWILDMTWLNLVELS KLPQFAEIMNQISRNEKGWKSWFDKDAPEEEIIPDGYNDSLDTCRKLLLIRSWCPDRTVF QARKYIADSLEDKYTEPVILNLEKTWEESDTRTPLICFLSMGSDPTIQIDALAKKLKLEC RTISMGQGQEVHARKLIQVSMQQGGWVLLQNCHLGLEFMEELLETLITTEASDDSFRVWI TTEPHDRFPITLLQTSLKFTNEPPQGVRAGLKRTFAGINQDLLDISNLPMWKPMLYTVAF LHSTVQERRKFGPLGWNIPYEFNSADFTASVQFIQNHLDECDIKKGVSWSTVRYMIGEVQ YGGRVTDDFDKRLLNCFARVWFSEKMFEPSFQFYTGYKIPLCKTLDQYFEYIQSLPSLDN PEVFGLHPNADITYQSNTASAVLETITNIQPKESGGGVGETREAIVYRLSEDMLSKLPPD YIPHEVKARLIKMGHLNSMNIFLRQEIDRMQRVISILRSSLSDLKLAIEGTIIMSENLRD ALDNMYDARIPQIWKRVSWDSSTLGFWFTELLERNAQFSTWIFEGRPNVFWMTGFFNPQG FLTAMRQEVTRAHKGWALDSVTIHNEVLRQTKEEIISPPVEGVYIYGLYMDGAAWDRRNG KLTESTPKVLFTQLPVLHIFAINSIAPKDPKLYVCPIYKKPRRTDLTFITVVYLRTVLSP DHWILRGVALLCDIK NT seq 13548 nt NT seq  +upstreamnt  +downstreamnt atgagcggcattccaaatctccaggaaacattaaaagagagacaggcaagatttagagaa gcaagggaaaatcggaaaacgaaaattgacccttcatacaaatatatatttgaaattcta gcggagaagcttggcctggacttggtaaccattgaagaattaattttggactgtccatct ctggacgcatttgctcaattttttatgaaagatggttgtaagacattgaaatttttgtac caagaaggagatgtccctggtattgaatgtggtcgaactattgctggagcaaccaaaggg gcaaaaatgatgagattgtatatagacaacgcagcccctgagaaactaaaaggattgtgt atattttttgttcgctgtcacaatgatattgctataaatgttaaaaatattcatgaggaa gtgctatttactgtactggatgcatcaacaggaatccttcctgggattaggaatatgctg tcaagtatatttgtgccagctattcttgcaacaaataattggggtgctctaaaccagtcc aagcaaggagaatctgaaaaacacattttcaccgaaaccatcaacagatacctttcattt ttagatggtgctagagtaagtattgagggcacagttaagttaaagaaggtagacaatgtc gatttttccaaactgcatacttttgaagaagtgacagctgcagccagcaattcagaaatg gttcgtcagctagaggatgtgctgatgacatggtacagacagatcgaacaggtacttatt gagagtgagcagatgagaaaggaagctgatgactcaggtccacttactgaattggaacac tggaaacgcatgtcagccaaattcaattatatcattgaacagattaaaggaccaagttgt aaggctgtcataaatgtgcttaatgttgcacactccaaactgttaaagaattggcgtgat ttggatgcaagaataacagatacagcaaatgaatcaaaagataatgtcagatatttgtac actttagaaaaagtgtgtcaacctctctataactatgacctagtttccatggcacatgga atacaaaatttgattaatgccatcagaatgattcacggtgtgtcacggtattataatact tcagagagaatgacctcgttgtttatcaaagtaacaaatcaaatggtgacagcatgtaaa gcatatattactgatggaggaactgtccacgtatgggatcaggaaactccacttgtatta aagaaaattcaggattgcattttcctattcaaggaatatcagacatcttttcataagaca aggaaacagattttagagtcctcaggagaaaaatcttttgaggtttcagaaatgtatata tttggaaaatttgaagctttctgcaaaagactggagaagattacagaaatgataacgatt gtgcagacatattcagccttgagtaattccaccatagagggaatagatattatggcaata aaattcaaaagtatatatcaaggcgttaagaaaaaacagtatgacattctggatccaaga aggacagaatttgatacagatttctcagagttcatgacaaaaatcaatggtttagagata caaatacaggcatttatgaacagtacttttggaaaaatcttgtcttctcagcaggccctt cagcttcttcaaagattccagaagctgaacatcccctgtcttcagttagaaataaaccat accatcgagcgtattcttcagtattacgtggctgaacttgaagctacaaagaagctttat cattctcaaaaagatgacccacctcttgctcgcaacatgccccctatagcaggcaaaata ctttgggtgaggcagctctatcgccggataagtgagcccatcaactatttcttcaaaaac tcagaaattttgtcaagtgcagaaggtaaagctgtcattcgtcagtataacaaaatttcc tatgttctggtggaattcgaggtggtctatcacacagcctgggtcagagagatctcgcag ttacagtatgctttacaagccacactttttgtgcgacacccagagacagggaagttgctg gttaattttgatcccaaaattttggaagttgttcgggaaactaagtgcatgataaaaatg aagctggatgtaccagaagaggcaaagagattgctaaaactggagaataaattgaaagca gataaattgcatttgcagggtcttctgcagtattatgatgagttatgtcaggaagtgcct tcagtgtttgtcaatctgatgaccccgagaatgaaaaaggtggaatctgtgttgagacaa gggctcacaatattaacatggtcatctttaacactagagagcttctttcaagaagttgac tcggttttggatatgttcaatcaacttttaaagaagatcagcgacttgtgtgaaatgcat attgatacagttctaaaggagatagccaaaactgtgttaatttccctgcctgaaagtggt gccaccaaagtagaagatatgttgacactcaatgagacatacacaaaagaatgggctgat atcctaaaccacaaaagtaagcatgtggaagaagctgtcaaagaacttatattaatattt gaagctatttatgaagttaaggacagtgggaaaacagcaaaaccattaccagaacagagg aaacatgttgcttttggaagtgaaacagaagagggtgaaaaccctgattatgagactaat atcctgcctcaggctgattttaatgataaagaagatgaatttaagaaggaatgtaaagag gtctatgcttttttctctcatcaattgctagacagtcttcaaaaagctacacggttatct ttggacacaatgaaaagaagaatatttgtttcaagccaatatggacgaaggcgatcagaa gatgttatttccttcataaaaactgaagtgcatcttgcgattccaaatgtggtaatggtt cctagtttggatgacattcaacaagccattaaccgtatgatccagctaaccctggaagtc agcagaggagtggctcactgggggcaacagccgacccgtcaagttaaacctgtcgtcacc agtcccagccgtactactgacctgatgcatttaaacacaacaaaacaggcaaagaaggaa gagaagcctgtggaagaagtaattactgcaagaaagctgaagaatttttatccaggggta gcggagcacaaggatatttccaaattggtcctcctcctttcttcctctgtgaattctcta cggaaggtggctcatgaggccttgcaggactttcaaaagtacaagacgctctggacagag gaccgagacgtgaaagtgaaggagtttttggctaacaacccctctctgactgaaaccaga tcagaaattctacactttgctacttttgaacaggagattgatgagttgaagcctattatt gttgtaggagcacttgaactgcatacagggccaatgaaattggccttatcaattgaggct aaagcatggaagatgttactctgtcgatatttgaatgaagaatacaaaaagaaaatgtca gacatgatagcattcatcaatgaatacttgaaaaagttatctagacctatccgtgattta gatgatgtcagatttgcaatggaagccttagcatgtatccgtgataatgaaattcaaatg gacatgactttgggaccaattgaagaagcctatgctattttaaacagatttgaagttgaa gtaaccaaagaagaatcagaagcagttgacaccttgagatattctttcaacagattgcag agcaaagctgtttctgtgcaagatgaactagttcaagtgcagccaaagtttaaaagtaat cttcttgaggccgtggaagtttttcgtgaggatgtaatgaacttcgcagaagcgtatgag atggaaggacccatggttccaaatataccaccccaagaagctagcaacaggctacagata tttcaggccaattttgatgatctgtggaggaagtttgttacatattcatctggtgaacaa ctttttggattgcctgtgactgattatgaggttttacacaaaactagaaaggaactcaac ttgctgcagaagctgtatggactctatgataccgtaatgagcaatattagtggttattat gaaatactttggggagatgtagacattgaaaaaattaatgcagaactgcaggaatttcaa aacagttgggacatttgcatatctgccattaaggaaaaggatattgaagccaagctgact caggtgattgaaaactggaccaaccagaacctgagttttgccgcatttaagggaaaggga gagctccttctcaaaggcactgaatcaggagaaattatcaccttgatggaggatagttta atggtcttaggttccttactaagcaacagatataatgctccatttaaaaaaaccatccag aattgggtgtataaattgtccacttcctcagatataattgaagagtggctagtagtccag aacctttgggtttatcttgaagctgtctttgtgggtggagatattgccaaacagctacct caggaagccaagcgttttcagaatattgacaagtcatggataaagataatgcagcgagct catgagaaccccaatgtgatcagttgctgtgttggagatgaaaccatggggcaactttta cctcatttgcacgaacagttggaagtatgtcagaagtcactcacggggtatttggagaag aagagattactgtttccaagattcttctttgtgtccgatccagttcttctggaaattctg ggacaagccagtgattcccacaccatacagccacatctccctgcagtatccgacaacata aatgaggtgacatttcatgcaaaagactacgatcgtatcctggccgtcatatcaagagaa ggagaaaaaattatgttggataatcctgttatggccaaaggtcctgtagagatttggctt atggatttgttaaaaatgcagatgtcgtcactgcataatataatcaggtctgcattctac caaatcagcgattcaggatttcaactcttaccttttctcaatcactttccagcacaggtg gggcttctgggaattcagatgttgtggacacatgattcagaagaggctttacataatgca aaagatgacaggaaaatcatgcaggtgaccaatcagaaatttttggatattctgaatatt ctcatcagtcagacaacacatgacctaagcaagtttgacagagtgaagtttgaaactctg ataaccatccatgtgcaccagagagatatttttgatgacttggtaaaaatgcatatcaaa tcagttactgattttgaatggctaaaacagagtagattttattttaaggaagacttggat caaactgtagtgtctattacagatgtggattttatttaccaaaatgaatttctgggatgc actgatcgtcttgttatcactccattaacagataggtgctatatcactttagcccaggct ttgggaatgaacatgggaggagctccggcaggacccgcgggcactggcaaaacagaaacc acgaaagacatgggaaggtgtttgggaaaatatgtggttgtgtttaactgctcagatcaa atggatttcagagggctcggaaggatttttaaaggtcttgcacaatcaggttcttggggc tgttttgatgagtttaacagaatagaattgcctgtattatcagtggcagcccaacagatt tatattgttctgacagcaagaaaagagagaaaaaaacagttcattttctctgatggtgat tgtgttgatttgaatccagaatttggaattttcctaacaatgaaccctgggtatgctggg cgccaggaactaccagaaaacttaaaaattcagtttagaactgttgctatgatggttcca gatagacagatcattatgcgagttaaacttgcaagctgtggttttcttgaaaacgtcgtc ttggctcaaaagttttatgttctttacaaactctgcgaagagcaacttaccaaacaggtt cattacgactttgggttgagaaatatcctatctgtcttgaggacactcggatctcaaaaa agagccagaccagaagacagtgaactaagcactgtcatgagaggactgagagatatgaac ctttccaaactggttgatgaagacgaacccctgttcctcagcttaatcaatgacctgttt ccaggactgcagctggatagtagtacgtatgcggagctgcaagctgcagtggccaaccag gttcagatagaaggtttgattaaccacccgccctggaatctcaaacttgtgcagttatat gagacgtctctggtccgtcatggtttgatgactctggggcccagtggttctgggaagacg actgtcataacaatcctgatgaaggcattgactgagtgcggaagacctcacagagagatg cgaatgaatcccaaagcgattaccgcgcctcagatgtttggcagactggacaccgctact aatgactggacagatgggattttttctactctgtggagaaaaacattaaaagctaaaaaa ggtgaaaacattttcctcattttagatggccccgtggatgccatttggatcgagaaccta aattctgtgttggatgacaataaaactctcacgttagctaatggagatcgcattcccatg gctccgaattgcaagcttttgtttgaagtccacaatattgagaatgcttcccctgccaca gtttccaggatgggcatggtctatatcagcagctctgcgctcagctggaggccgatattg caggcgtggttgaagaagcgcaccgcgcaggaagcttctgtattccagactctgtatgat aaaatatttgaagatatatatacattcatgaaactgaacctcaatccaaaaatgcagctc ctggagtgcaactatatcatgcagtctctcactctactggaaggtttaattccctccaaa gaagaaggtggtatttcatgtgtcgaacatcttcataaattatttgtgtttggcctaatg tggagtttaggagcccttttggaattggaaagcagagaaaagcttgaggcctttttacga agtcatggaagcaagttagacttgccagaaatacctaaaggcacaaatcagaccatgtat gagttttatgttactgattatggtgattgggaacactggaataagaaactacagccatat tattatccaactgacagtattccagaatattcatcaattttggttccaaatgttgacaat attagaacaaattttttgatagacaccattgcaaaacaatataaagctgttttgctcacg ggagagcaggggactgcgaaaactgtaatgattaaagcctatttgaaaagatacgatcct gaagtacagttatccaaaagtctaaacttttcatctgccacagaaccagtcatgttccag agaaccattgaaagctatgtggataaacgaatgggaagcacatatgggccaccaggaggc agaaaaatgactgtatttattgatgatattaatatgccggtgattaatgaatggggagat caggtaactaatgagatcgtgcgacaaatgatggaaatggaaggaatgtatagcttagat aagcctggagacttcactactattgttgatgtgcagctcatagcagcaatgatccaccct ggaggtggtcgaaatgatattccacaacgtttaaaaagacagtttactgtgtttaattgc acattgccttcaaatgcttcaatagacaaaatttttggacttattggctgtgggtacttt gatccttgcagaaagttcaaacctgaaatatgtgagatgattggaaatttagtttcagca ggcagagtgctgtggcagtggactaaggtgaagatgctaccaactccttctaaatttcac tacattttcaatcttcgagatctttccagaatttggcaaggaatgttaaccataaaatcc gaggagtgtgattcgatatctgttctcctatcacttttcaaacacgagtgcaacagagta attgcagacagatttataacttctgaagatgagcagtggtttaatatccatcttattcac gccattgaggaaaatattagcccagatgtggcatcttatatccttcccgaaccatacttt gtagattttctccgggagatgcctgaaccaactggtgacgaacctgaagacactgtgttt gaagtacccaaagtttatgaattggtaccatcctttgacttcctgtctgaaaaactccag ttctaccagagacagttcaatgaaatcattagaggaacatctcttgatctagtgtttttt aaagatgcaatgactcatcttattaagatctcacgaataattcgaacatcatgtggaaat gcattgctggtgggtgttggcggttcaggaaaacaaagtctttctagactggcttctttt atagctggatatcaaatattccagattacattaaccaggtcttataatgtgaataatctg acagaggacttaaaaggtctgtacaaagttgctggtgctgaaggaaaaggtatcaccttc atctttactgacaatgaaataaaagatgaggcatttctagaatatcttaacaacctgcta tcttcaggggagatctccaatctgtttgcgcgagatgagatggatgaaatcacccaaggt ctgatatcggtaatgaaaaaggagctgcctcgccaccctcctacctttgataatctgtat gaatacttcatttcaagatcaaggaagaacttgcatgttgttctctgcttttctccagtt ggtgagaagttccgtgcccgttctttgaaatttcctggcttgatatcaggttgcaccatg gactggtttagtcgctggccaaaggaggctttgattgctgtggcctcctatttcctttca ggctacggtattgtctgctccagtgacactaaaagacaagttgtagaaacaatgggcctc ttccatgacatggtttccgagagctgtgaaagttatttccaaagataccgccgaagagct cacgtgactcccaagtcttatctctcctttataaatggttataaaaccatttatgctgaa aaggtgaaatttatcaatgaacaagctgaacgtatgaatattggtcttgataagcttatg gaggcaagtgaatctgttgctaagctctctcaggatcttgcggtaaaggagaaggagctg gcagtggcttccgtaaaagcagatgaagtgttagcagaagtcacagtaagtgctcaggct tcagccaaagtcaaaaatgaagtgcaggaggtgaaagacaaagcccaaaaaatcgtggat gaaattgatagtgaaaaagtaaaagctgagaccaagctggaggcagctagaccggccctg gaagaagcagaggcggccttgaacactatcaaaccaaatgatattgccacagtcaggaaa cttgcaaagcccccgcatcttattatgagaatcatggactgtgttctgctactatttcaa aagaaaattgaccctgtcactatggatccagaaaaaccttgctgcaaaccatcctgggga gagtcattaaaattaatgagtgcaacagggttcctgtggagccttcagcagtttcccaag gatactataaatgaagagactgttgagttgctgcagccatattttaacatggatgattat tctttggaaaatgccaaaaaagtctgtgggaatgtggctggcctgctgtcctggaccctt gctatggccacattttatggtgtcaacagagaggtgttgcctctgaaggctaacctggcc aagcaggagggccgcctagcagtcgccaatgctgagctggggaaggcacaggaactgctg gatgagaaacaagccgagctggataaagtacaagcaaaatttgatgcagcgatgaatgag aaaatggatttgctaaatgatgcagatatgtgccggaaaaagatgcaggcagcttccact ctcatcgatgggctgagtggagaaaaggtccgatggacccagcaaagcaaagagttcaaa gcccagattaacagacttgtaggtgacattcttctgtgcactggattcctttcctacctt ggtcctttcaatcagatatttaggaactatttgcttaaagatcagtgggagatagaactg agagctcggaagattcctttcaccgaaaacctgaatcttatttcaatgttggtggacccg ccaaccattggggagtgggggctgcagggattaccaggagatgacctctccattcagaat ggcatcattgtgacaaaggccaccagatacccactcctcattgacccacaaactcaaggc aaaacttggattaaatcaaaggaaagagaaaatgacttgcaggtaacatctctgaaccat aaatatttccgcacacacttggaagacagcctttccttgggccgaccccttctcattgag gatattcgtgaggagctggatccagccttggataatgtattagaaaagaatttcattaaa tcaggcaccacattcaaggtgaaagtcggtgataaggaatgcgatatcatggatacattt aaactttatattactacaaagttaccaaaccctgccttcacccctgagatcaatgctaaa acatcagtcattgattttactgtcaccatgaaaggccttgaaaatcagttactaaggaga gtgattttaactgagaaacaggaattagagtctgagagggttaaacttttggaggatgtg actttcaacaagcggaagatgaaggaactggaagacaaccttctctacaaattaagcgcc acaaaaggttccttggtagacgacgaatctctcatcggtgtcctccgaaccaccaagcag acagcatctgaagtaagtgaaaagctgcacgtggccgcagaaacggagatcaaaattaac acggctcaggaggagttccggcctgcagccacccgtgggagcatcctctactttctcatc acagagatgagcatggtcaacatcatgtaccagacctcgctggcccagttcttgaagtta tttgaccagtccatggccagatctgagaagtctccactacctcaaaagaggattacgaat atcattgagtatctgacgtatgaggtttttacatactctgtcagaggcctgtacgaaaac cacaaattcctctttgtactcctgatgaccttgaagatcgatcttcagagaggaacagtg aagcacagagagtttcaggctctcattaaagggggagcagctctggatctgaaagcctgc cctcccaagccgttccgctggatccttgatatgacctggctgaatcttgtggagctgagc aaacttccacagtttgcagagattatgaaccagatatctcgtaatgagaagggatggaaa agctggtttgataaagatgctccagaggaggaaattatccctgatggatataacgattca ctggatacctgccgcaaacttttacttatcaggtcttggtgcccagaccgtactgttttt caagcaagaaagtacattgcagattctttggaggacaagtacacagaaccagttatccta aacctggagaaaacttgggaagaaagtgataccaggacacctttgatatgtttcctgtcc atgggatctgatcccacaattcaaattgatgcattggccaagaaactgaagctggaatgc agaactatctcaatggggcaaggacaagaggtacatgctcgaaagctgattcaggtgtcc atgcagcagggtggctgggttttactgcaaaattgtcaccttggcctagaattcatggaa gaattgctagagacgttaattaccacggaagccagtgatgactctttccgagtatggata actactgagccccatgatcgattcccaattacgttgcttcagacttctctcaaattcact aatgagccgccccaaggcgtacgcgcgggtttgaaaagaacatttgctggaattaatcaa gaccttctggatatcagtaatttacccatgtggaagccgatgctttacacagtagcattt ttacactccactgtgcaggagcgacgcaaatttggtcccttaggatggaatattccctat gaattcaattctgctgattttacagccagtgtccagtttattcagaatcaccttgatgaa tgtgatattaaaaagggtgtttcatggagtacggttcggtacatgattggagaagtacaa tatggaggcagagtgacagatgactttgataaacgtctacttaattgctttgctagagtc tggttcagtgagaagatgtttgaaccatcgttccagttttataccgggtataaaatcccc ttgtgcaaaaccctggatcagtattttgagtacatccagtcattgccatccctagataac cccgaagtctttgggctgcaccctaatgccgatatcacgtatcagagtaacactgcttct gctgttcttgaaacaattaccaacattcaacccaaagagagtggagggggagtcggagag acccgggaagccattgtttatagattatctgaagatatgctgagcaaactgcctcctgac tacattcctcatgaggtgaaggctcgtttgatcaagatgggacatcttaattcaatgaac atatttctgagacaagaaattgacagaatgcaaagagtcatctcaatacttcgcagtagc ttgagtgatctaaaattggccattgagggaacaatcattatgagtgagaatttgagagac gccctggacaacatgtatgatgctcgcatacctcagatctggaaaagagtgtcctgggat tcatccacactgggcttctggttcactgaacttctggaaagaaacgctcagttttctact tggatatttgaggggaggcccaatgtattttggatgactggtttctttaatccgcaaggc ttcctcacagcaatgaggcaggaagtgacccgagcccacaaaggctgggccctggactct gtgaccatccacaacgaagttctgcggcagaccaaggaggagatcatatcaccccccgtg gaaggtgtatatatttatgggctctacatggatggagcagcctgggacagacggaatgga aagcttacagaatccactcccaaggtgctcttcacacagctgcctgtgctgcatatcttt gccattaattccatcgcgcccaaggaccccaagctgtatgtgtgtcctatttacaagaaa ccaaggcgtactgacttgaccttcatcaccgtggtgtacctgcgaacagttttgtcccca gatcactggatcctgagaggagtggctcttttgtgtgacatcaagtaa

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