Puma concolor (puma): 112864274
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Entry
112864274 CDS
T08890
Symbol
SRD5A2
Name
(RefSeq) 3-oxo-5-alpha-steroid 4-dehydrogenase 2
KO
K12344
3-oxo-5-alpha-steroid 4-dehydrogenase 2 [EC:
1.3.1.22
]
Organism
pcoo
Puma concolor (puma)
Pathway
pcoo00140
Steroid hormone biosynthesis
pcoo01100
Metabolic pathways
pcoo05215
Prostate cancer
Module
pcoo_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
pcoo00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
112864274 (SRD5A2)
09160 Human Diseases
09162 Cancer: specific types
05215 Prostate cancer
112864274 (SRD5A2)
Enzymes [BR:
pcoo01000
]
1. Oxidoreductases
1.3 Acting on the CH-CH group of donors
1.3.1 With NAD+ or NADP+ as acceptor
1.3.1.22 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+)
112864274 (SRD5A2)
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SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Steroid_dh
DUF1295
DUF6832
Motif
Other DBs
NCBI-GeneID:
112864274
NCBI-ProteinID:
XP_025783132
UniProt:
A0A6P6I4T7
LinkDB
All DBs
Position
Unknown
AA seq
254 aa
AA seq
DB search
MRVPCQQSPVLAGSAALAALGALVLYLAEPSGYGKYSERAMPAAARLPARAAWFLQELPS
FAVPAGILARQPRALFGPPATVLLGLFCGHYFYRTFVYSLRTRGRPFPVVFLVKGFVFCM
GNGLLQGYYLIYCAEYPADWYTDIRFSLGVFLFILGMGINIHSDCILRQLRKPGEVIYRI
PQGGLFTYVSGANFLGEIIEWIGYALATWSLPALAFAFFSLCFLGLRAFHHHRFYLKMFE
DYPKSRKALIPFIF
NT seq
765 nt
NT seq
+upstream
nt +downstream
nt
atgcgggttccctgccagcagagcccggtgctggcgggcagcgccgccctggccgccctg
ggggcattggtcctgtacctggctgagccctccggctacgggaagtactcggagcgcgca
atgcccgccgctgctcgcctgccagcccgcgcagcctggttcctgcaggagttgccatcc
ttcgcggtgcctgcggggatcctcgcccggcagccgcgtgctctcttcggccctccggcc
accgtgcttctgggcctcttctgcggacattacttctacaggacatttgtttactcattg
cgtactagagggaggccttttccagttgtgttcctcgtcaaaggctttgttttctgcatg
ggaaatggacttctccaaggctactatctgatttactgtgctgaataccctgctgattgg
tacacagacatacggtttagcctgggtgtcttcttatttattttgggaatggggatcaac
attcatagcgactgtatactgcgccagctcaggaagcctggagaagtcatctataggatt
ccacaaggtggcttgtttacctacgtttctggagccaatttccttggtgagatcattgaa
tggatcggctatgccctggccacgtggtcgctcccagcgcttgcatttgcctttttctca
ctttgtttccttgggctgcgagcttttcaccaccataggttctacctcaagatgtttgag
gactaccccaaatctcggaaagccctcattccattcatcttttaa
DBGET
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