Puma concolor (puma): 112864460
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Entry
112864460 CDS
T08890
Symbol
ERN1
Name
(RefSeq) serine/threonine-protein kinase/endoribonuclease IRE1
KO
K08852
serine/threonine-protein kinase/endoribonuclease IRE1 [EC:
2.7.11.1
3.1.26.-]
Organism
pcoo
Puma concolor (puma)
Pathway
pcoo04140
Autophagy - animal
pcoo04141
Protein processing in endoplasmic reticulum
pcoo04210
Apoptosis
pcoo04932
Non-alcoholic fatty liver disease
pcoo05010
Alzheimer disease
pcoo05012
Parkinson disease
pcoo05014
Amyotrophic lateral sclerosis
pcoo05016
Huntington disease
pcoo05017
Spinocerebellar ataxia
pcoo05022
Pathways of neurodegeneration - multiple diseases
pcoo05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
pcoo00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
112864460 (ERN1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
112864460 (ERN1)
09143 Cell growth and death
04210 Apoptosis
112864460 (ERN1)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
112864460 (ERN1)
05012 Parkinson disease
112864460 (ERN1)
05014 Amyotrophic lateral sclerosis
112864460 (ERN1)
05016 Huntington disease
112864460 (ERN1)
05017 Spinocerebellar ataxia
112864460 (ERN1)
05022 Pathways of neurodegeneration - multiple diseases
112864460 (ERN1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
112864460 (ERN1)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
112864460 (ERN1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pcoo01001
]
112864460 (ERN1)
Enzymes [BR:
pcoo01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
112864460 (ERN1)
Protein kinases [BR:
pcoo01001
]
Serine/threonine kinases: Other
IRE family
112864460 (ERN1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Ribonuc_2-5A
Pkinase
PK_Tyr_Ser-Thr
PQQ_2
PQQ
Pkinase_fungal
Kdo
APH
Motif
Other DBs
NCBI-GeneID:
112864460
NCBI-ProteinID:
XP_025783273
UniProt:
A0A6P6I855
LinkDB
All DBs
Position
Unknown
AA seq
860 aa
AA seq
DB search
MCLGCGLSNLSVFIFEIFGSPSTVTLPETLLFVSTLDGSLHAVSKRTGSIKWTLKEDPVL
QVPTHVEEPAFLPDPNDGSLYTLGGKNNEGLTKLPFTIPELVQASPCRSSDGILYMGKKQ
DIWYVIDLLTGEKQQTLSSAFADSLCPSTSLLYLGRTEYTITMYDTKTRELRWNATYFDY
AASLPEDDGDYKMSHFVSNGDGLVVTVDSESGDVLWIQNYASPVVAFYVWQREGLRKVMH
INVAVETLRYLTFMSGEVGRITKWKYPFPKETEAKSKLTPTLYVGKYSTSLYASPSMVHE
GVAVVPRGSTLPLLEGPQTDGVTIGDKGECVITPSTDLKFDPGLKGKSKLNYLRNYWLLI
GHHETPLSASTKMLERFPNNLPKHRENVIPADSEKKSFEEVINLVEQTSENAPTAVSQEV
EEKFEHAPAKPEAPVDSMLKDIATIILSTFLLIGWVAFIITYPLPVILVLRGMFDNRDVA
VKRILPECFSFADREVQLLRESDEHPNVIRYFCTERDRQFQYIAIELCAATLQEYVEQKD
FAHLGLEPITLLQQTTSGLAHLHSLNIVHRDLKPHNILLSMPNAHGRIKAMISDFGLCKK
LAVGRHSFSRRSGVPGTEGWIAPEMLSEDCKDNPTYTVDIFSAGCVFYYVISEGSHPFGK
SLQRQANILLGAYSLDCLHPEKHEDVIARELIEKMIAMDPQKRPSAKHVLKHPFFWSLEK
QLQFFQDVSDRIEKESLDGPIVKQLERGGRAVVKTDWRENITVPLQTDLRKFRTYKGGSV
RDLLRAMRNKKHHYRELPAEVRETLGSLPDDFVRYFTSRFPHLLPHTYRAMEPCSHERLF
QPYYFHEPPELRPPVTPDAL
NT seq
2583 nt
NT seq
+upstream
nt +downstream
nt
atgtgccttggatgcgggctctctaacctcagcgtcttcatctttgagatttttggaagt
cccagcacagtgacacttcccgaaaccttgttgtttgtgtcaaccctggatggaagcttg
catgctgtcagtaagaggacgggctcaatcaaatggactttaaaagaagatccggttctg
caggttccaacgcatgtggaagagcctgccttcctcccagatcccaatgatggcagcctg
tatacacttgggggcaagaataatgaaggcctgacgaaacttccctttaccatcccagag
ctcgtacaggcatccccatgccgaagttcagatggaattctctacatgggtaaaaagcag
gacatttggtatgttattgatcttctgaccggggagaagcagcagactttgtcatcggcc
tttgcagacagtctctgcccatcaacctctctgctgtatctcgggcgaacagagtacaca
atcaccatgtacgacaccaaaacccgcgagctccggtggaatgccacctacttcgactac
gcggcctcactgccggaggacgacggggactacaagatgtcccactttgtgtccaacggc
gatgggctggtggtgaccgtggacagtgaatctggcgacgtcctgtggatccaaaactac
gcttcccctgtggtggccttttatgtctggcagcgggagggtctgaggaaggtgatgcac
atcaacgtcgcagtggagacgctgcgctatctgaccttcatgtctggggaggtgggccgc
atcaccaagtggaagtacccgttccccaaggagacggaggccaagagcaagctgacgccc
accctgtatgtcgggaaatactctaccagcctgtatgcctccccctccatggtgcacgag
ggggtcgccgttgtgccccggggcagcacacttcctttgctggaaggcccccagactgac
ggggtcaccattggggacaaaggggagtgtgtgatcacgcccagcacagacctaaagttt
gaccctgggctcaaagggaagagcaagctcaactacttgaggaactactggcttctgata
ggacaccatgaaacccccctgtctgcgtctaccaagatgctggagagattccccaataat
ctgcccaaacatcgagaaaatgtgattcctgccgattcagagaagaagagctttgaggaa
gttatcaacctggtggagcagacttcagaaaacgcgcccaccgccgtttcacaggaggtg
gaggagaagttcgagcatgcccccgctaagcccgaggcccccgtggactctatgctgaag
gacatagccaccatcatcctgagcaccttcctgctcatcggctgggtggccttcatcatc
acctaccccttgcctgtgatccttgtcctcaggggcatgttcgacaaccgcgacgtggcc
gtcaagaggatcctccccgagtgtttcagtttcgcggaccgtgaggtccagctgcttcgg
gaatcagacgagcaccccaacgtgattcgttacttctgcacggagagggaccggcagttc
cagtacattgccatcgagctgtgtgcggccaccctgcaggagtacgtggagcagaaggac
ttcgcccacctcggcctggagcccatcaccttgctgcagcagaccacctcgggcctggcc
catttgcactccctcaacattgttcacagagacctgaagccccacaacattctcctgtcc
atgcccaacgcacatggcaggatcaaggccatgatctctgacttcggcctctgcaagaag
ctggctgtgggcaggcacagtttcagccgccgctcaggagtgcctggcacagaaggctgg
atcgctccggagatgctgagcgaggactgtaaggacaatcctacctacacagtggacatc
ttctctgcgggctgtgtcttttactacgtgatatctgagggcagccacccttttggcaag
tccctgcagcggcaggccaacatcctcctgggcgcctacagcctcgactgcttacacccg
gagaagcacgaagacgtcattgcccgggaattaatagagaagatgatcgcaatggatcct
cagaaacgcccctctgcgaagcatgtgctgaagcacccgttcttctggagcctggaaaag
cagctccagttcttccaggacgtgagtgaccgaatagaaaaggaatccctggacggcccg
atagtgaagcagctggagcgaggcgggagagccgtggtgaagacggactggagagagaac
atcaccgtccccctgcagacagatctgcgtaaattcagaacctataaaggtggctctgtc
cgcgaccttctccgagccatgagaaacaagaagcaccactaccgggagctccccgcggag
gtgcgggagacgctgggctctctccccgacgactttgtgcgctacttcacgtcccgcttc
ccccacctcctcccccacacctaccgggccatggagccctgcagccacgagaggctcttc
cagccttactacttccacgagcccccagagctccggccccctgtgactccagacgccctt
tga
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