KEGG   Puma concolor (puma): 112864599
Entry
112864599         CDS       T08890                                 
Symbol
MAP2K6
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 6
  KO
K04433  mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
Organism
pcoo  Puma concolor (puma)
Pathway
pcoo04010  MAPK signaling pathway
pcoo04015  Rap1 signaling pathway
pcoo04218  Cellular senescence
pcoo04380  Osteoclast differentiation
pcoo04620  Toll-like receptor signaling pathway
pcoo04664  Fc epsilon RI signaling pathway
pcoo04668  TNF signaling pathway
pcoo04750  Inflammatory mediator regulation of TRP channels
pcoo04912  GnRH signaling pathway
pcoo04935  Growth hormone synthesis, secretion and action
pcoo04936  Alcoholic liver disease
pcoo05014  Amyotrophic lateral sclerosis
pcoo05022  Pathways of neurodegeneration - multiple diseases
pcoo05132  Salmonella infection
pcoo05135  Yersinia infection
pcoo05145  Toxoplasmosis
pcoo05161  Hepatitis B
pcoo05163  Human cytomegalovirus infection
pcoo05167  Kaposi sarcoma-associated herpesvirus infection
pcoo05169  Epstein-Barr virus infection
pcoo05170  Human immunodeficiency virus 1 infection
pcoo05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
pcoo05417  Lipid and atherosclerosis
pcoo05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pcoo00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    112864599 (MAP2K6)
   04015 Rap1 signaling pathway
    112864599 (MAP2K6)
   04668 TNF signaling pathway
    112864599 (MAP2K6)
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    112864599 (MAP2K6)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    112864599 (MAP2K6)
   04664 Fc epsilon RI signaling pathway
    112864599 (MAP2K6)
  09152 Endocrine system
   04912 GnRH signaling pathway
    112864599 (MAP2K6)
   04935 Growth hormone synthesis, secretion and action
    112864599 (MAP2K6)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    112864599 (MAP2K6)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    112864599 (MAP2K6)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    112864599 (MAP2K6)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    112864599 (MAP2K6)
   05161 Hepatitis B
    112864599 (MAP2K6)
   05163 Human cytomegalovirus infection
    112864599 (MAP2K6)
   05167 Kaposi sarcoma-associated herpesvirus infection
    112864599 (MAP2K6)
   05169 Epstein-Barr virus infection
    112864599 (MAP2K6)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    112864599 (MAP2K6)
   05135 Yersinia infection
    112864599 (MAP2K6)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    112864599 (MAP2K6)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    112864599 (MAP2K6)
   05022 Pathways of neurodegeneration - multiple diseases
    112864599 (MAP2K6)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    112864599 (MAP2K6)
   05418 Fluid shear stress and atherosclerosis
    112864599 (MAP2K6)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    112864599 (MAP2K6)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:pcoo01001]
    112864599 (MAP2K6)
Enzymes [BR:pcoo01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     112864599 (MAP2K6)
Protein kinases [BR:pcoo01001]
 Serine/threonine kinases: STE group
  STE7 family
   112864599 (MAP2K6)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Pkinase_fungal Seadorna_VP7 Choline_kinase Haspin_kinase CLP1_P DUF4344 APH
Other DBs
NCBI-GeneID: 112864599
NCBI-ProteinID: XP_025783423
UniProt: A0A6P6I8K1
LinkDB
Position
Unknown
AA seq 278 aa
MELGRGAYGVVEKMRHVPSGQIMAVKRIRATVNSQEQKRLLMDLDISMRTVDCPFTVTFY
GALFREGDVWICMELMDTSLDKFYKQVIDKGQTIPEDILGKIAVSIVKALEHLHSKLSVI
HRDVKPSNVLINTLGQVKMCDFGISGYLVDSVAKTIDAGCKPYMAPERINPELNQKGYSV
KSDIWSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPGDKFTEEFVDFTSQCLK
KNSKERPTYPELMQHPFFTLHESKATDVASFVKLILGD
NT seq 837 nt   +upstreamnt  +downstreamnt
atggaactggggcgaggtgcgtacggggtcgtggagaagatgcgacacgtgcccagcggg
cagatcatggcggtgaagcggatccgggccacagtaaatagccaggagcagaaaaggcta
ctgatggatttggatatttccatgaggacagtggactgtcctttcacagtcaccttttat
ggtgcactcttccgggagggtgatgtttggatttgcatggaactcatggatacgtcgcta
gataagttctacaaacaagtgattgacaaaggccaaacaattccagaggacatcttaggg
aaaatagcagtttctattgtaaaggcgttagaacatttacacagtaagctctctgtcatt
catcgagacgtcaagccttccaacgtgctgatcaacactctgggccaagtaaagatgtgc
gattttggaatcagtggctaccttgtagactcagtcgctaaaaccattgatgccggatgc
aaaccgtacatggcccccgaaagaataaacccagagctcaatcagaagggatatagtgtg
aagtctgacatttggagtctgggcatcacaatgattgagttggcgatccttcggtttccc
tatgactcttggggaactcccttccaacagctcaagcaggtggtagaggagccctcacca
cagctcccgggagacaagttcaccgaagagtttgttgactttacctcacagtgcttgaag
aagaattccaaagaacggccaacgtatccagaacttatgcaacatccatttttcacccta
cacgaatccaaagcaacagacgtggcatcttttgtaaaattgattcttggagactaa

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