Puma concolor (puma): 112866887
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Entry
112866887 CDS
T08890
Symbol
ATIC
Name
(RefSeq) bifunctional purine biosynthesis protein PURH
KO
K00602
phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:
2.1.2.3
3.5.4.10
]
Organism
pcoo
Puma concolor (puma)
Pathway
pcoo00230
Purine metabolism
pcoo00670
One carbon pool by folate
pcoo01100
Metabolic pathways
pcoo01523
Antifolate resistance
Module
pcoo_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
pcoo00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
112866887 (ATIC)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
112866887 (ATIC)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
112866887 (ATIC)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
pcoo04147
]
112866887 (ATIC)
Enzymes [BR:
pcoo01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.3 phosphoribosylaminoimidazolecarboxamide formyltransferase
112866887 (ATIC)
3. Hydrolases
3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
3.5.4 In cyclic amidines
3.5.4.10 IMP cyclohydrolase
112866887 (ATIC)
Exosome [BR:
pcoo04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
112866887 (ATIC)
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SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
AICARFT_IMPCHas
MGS
Motif
Other DBs
NCBI-GeneID:
112866887
NCBI-ProteinID:
XP_025785635
UniProt:
A0A6P6IBV7
LinkDB
All DBs
Position
Unknown
AA seq
563 aa
AA seq
DB search
MAPGQLALFSVSDKTGLVEFARNLTSVGLNLIASGGTAKALRDAGLAVRDVSELTGFPEM
LGGRVKTLHPAVHAGILARNIPEDNADMARLDFDLIRVVVCNLYPFVKTVASPDVTVEQA
VEQIDIGGVTLLRAAAKNHARVTVVCEPEDYVAVCTEMQNSDSKDTSLETRRQLALKAFT
HTAQYDEAISDYFRKQYSKGISQMPLRYGMNPHQTPAQLYTLKPKLPITVLNGAPGFINL
CDALNAWQLVKELREALDLPAAASFKHVSPAGKALLSEWADRMSSFGDFIALSDICDVPT
AKIISREVSDGIVAPGYEDEALKILSKKKNGSYCVLQMDPSYSPDENEVRTLFGLRLSQK
RNNGVIDKSLFSNVVTKNKDLPESALRDLIVATIAVKYTQSNSVCYAKNGQVIGIGAGQQ
SRIHCTRLAGDKANYWWLRHHPQVLSMKFKTGVKRAEISNAIDQYVTGTIGEDEDLVKWK
ALFEEVPELLTEAEKKEWVDKLNEVSISSDAFFPFRDNVDRAKRSGVAYIAAPSGSAADR
VVIEACDELGIILAHTNLRLFHH
NT seq
1692 nt
NT seq
+upstream
nt +downstream
nt
atggcacccggccagctcgccttatttagtgtctctgacaaaacgggcctcgtggaattt
gccagaaacctaacttctgttggtttgaatttgatcgcttctggagggactgcaaaagct
ctcagggatgcaggtctggcagtcagagatgtctccgagctgacaggatttcctgaaatg
ttaggggggcgtgtgaaaaccttgcatcctgcagtccatgctggaatcttggctcgtaat
atcccagaagataatgctgacatggctagacttgatttcgatcttatcagggttgtcgtc
tgtaatctgtatccctttgtgaagacagtggcttctccagatgtaactgttgaacaggct
gttgagcagattgatattggtggagtaaccctcctgagagcagcagccaaaaaccacgct
cgagtaacagtagtatgtgaacctgaggactatgtggccgtttgcacagagatgcagaac
tccgacagtaaagacacctccttggagactagacgccagttagccttgaaggctttcact
catacagcacaatatgatgaagcgatttcagattacttcaggaaacagtatagtaaagga
atatctcagatgcccttgaggtatggaatgaatcctcaccaaactcctgcccagttatat
acgctgaagcccaagcttcccatcacagttctaaatggagcccctggatttataaacttg
tgtgatgctttgaatgcctggcagctggtgaaggaactcagagaagctttagaccttcct
gctgctgcctctttcaaacatgtcagcccagcaggtaaagcactgctttctgaatgggct
gataggatgtcttcatttggtgactttatcgcattatctgatatttgtgatgtccctact
gccaaaattatctccagagaggtatctgatggtatcgtcgccccaggatatgaagacgaa
gctttgaaaatactttctaaaaagaaaaacgggagctactgtgttcttcagatggaccca
tcttacagtccagatgaaaacgaagttcgaactctctttggtcttcgtttaagtcagaag
agaaataatggtgtcattgacaagtcattgtttagcaatgttgtgaccaagaataaagat
ttgccagagtctgcgctcagagacctcattgtagccaccattgctgtgaagtacacgcag
tctaactccgtgtgctatgccaagaatggtcaggttattggcattggagcaggacagcag
tctcgaatacactgcacacgccttgcaggggataaggcgaactactggtggcttagacat
catccacaagtgctttcaatgaagtttaaaactggagtgaagagagcagaaatctccaat
gccattgatcagtatgttactggaaccattggtgaggatgaagatttggtaaagtggaag
gcattgtttgaggaagtccctgaactgctaactgaagcagagaagaaagaatgggttgac
aaacttaatgaagtttctatcagctctgatgccttctttcctttcagagataacgtagac
agagctaaaaggagcggcgtggcatacattgctgctccttctggttctgctgccgacaga
gttgtgatagaggcttgtgatgaactgggaataattctcgctcatacgaatcttcggctc
tttcatcactga
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