Puma concolor (puma): 112868919 Help Entry 112868919         CDS       T08890                                  Symbol DNAH6 Name (RefSeq) dynein heavy chain 6, axonemal   KO K10408   dynein axonemal heavy chain Organism pcoo  Puma concolor (puma) Pathway pcoo04814   Motor proteins pcoo05014   Amyotrophic lateral sclerosis pcoo05016   Huntington disease pcoo05022   Pathways of neurodegeneration - multiple diseases Brite KEGG Orthology (KO) [BR:pcoo00001]  09140 Cellular Processes   09142 Cell motility    04814 Motor proteins     112868919 (DNAH6)  09160 Human Diseases   09164 Neurodegenerative disease    05014 Amyotrophic lateral sclerosis     112868919 (DNAH6)    05016 Huntington disease     112868919 (DNAH6)    05022 Pathways of neurodegeneration - multiple diseases     112868919 (DNAH6)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    03037 Cilium and associated proteins [BR:pcoo03037]     112868919 (DNAH6)    04812 Cytoskeleton proteins [BR:pcoo04812]     112868919 (DNAH6) Cilium and associated proteins [BR:pcoo03037]  Motile cilia and associated proteins   Dynein arm    112868919 (DNAH6) Cytoskeleton proteins [BR:pcoo04812]  Eukaryotic cytoskeleton proteins   Microtubules    Tubulin-binding proteins     Dyneins      112868919 (DNAH6) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  AAA_6 DHC_N2 Dynein_C AAA_8 AAA_9 AAA_7 AAA_lid_11 MT Dynein_heavy Dynein_AAA_lid AAA_5 AAA_lid_1 AAA AAA_18 AAA_22 AAA_16 nSTAND3 TsaE Sigma54_activat DEAD Caudo_TAP Motif Other DBs NCBI-GeneID:  112868919 NCBI-ProteinID:  XP_025787700 UniProt:  A0A6P6IHL3 LinkDB All DBs Position Unknown AA seq 4153 aa AA seqDB search MAFHTSAKDAKLKNTEKQVENPILERLNNIQKKGRLSFIVPTENESDTQFLTFRHSTKAQ ERTRKRQQPIRLEPLPVLKVYQDHKRPEYIYEQNRLQLISSGIIKPPGSTEERSSTKLSV QFLEPQYTVRKKKQQPSAEMFSPSPPKLSRTSIGRRGLYGTSSSAYPKYFFHDREEVVKA NVCNPLQIIKIIRENEHLGFLYMIPAVPRSSTEYDTYNLKVVSYENINKNDYYTISKKAI THIYNEDIEYIEIDRWEQEYLYHRELTKIPIFALFRKWKAFNVWKKNVRSKKISGCRQSL QKNLFIVNPHLRPALLKINELCYNLSFIRLCYIEKCHTYTLQEFKTTQIIWLEEVTMRLE EFRNEAKVVVRKACRIALHAAGFIPDDCQHKPVEDYCKMPDGEGLTELPAYSDSEKMTYT EQASKRHHCMRLTCFIRLNDYLIENTMHILTVNSVNSLLNYLTDKLKRTPSEDVIQKWIT EEKPHVTDKKGASVVEKQEEDESLIPMFLTELILTVQSLLFEPSLEDFLAGISDAINQFQ NTVLSVPNLVPDTYFDAFTRPYINNKLEEKTCGFGPSLSAVFDDDKNFHTIILQIKETIQ AAFESARLYAATFEKFHIFFKENESLDLQALKLQEPDVKFFGEQLEKYHRQHKDAIALRP TRNVGLLLIDTKLLKEKLIPSPLRCLEVLNYMLPRQSKKKVDAIISEAQDAEYKLEFVPT TTIEYVNSLVFLDEIQERIESLEDEGNVVIQMYKLIEQYQVPTPPEDFAVFATMKPSIVA VRNAIDKSVGDRETSIKQFSLHLGRDLEDLANEVNEVKLHAQDPQILDITADQDKIKLML HDLQLVLDDLQKRAFQYKSYQKNFKIEVSKFEALEEVSAELKLKQLLWDSLSEWDQLQQE WLKSKFDGLDPEVLNSQVSKYAKFVTQLEKGLPPNSVVPQLKCKVEKMKEKLPVIIDLRN PTLKPRHWAAIEQTVDATLVDLDIPLTLEKLSELHVFDFGQEIQDISGQASGEAALEIIL KKVEDSWKTTEFVVLPHRDSKDVFILGGTDDIQVLLDDSTINIATIASSRYVGPLKTRVD DWQKQLALFNQTLEEWLNCQRNWLYLESIFNAPDIQRQLPAEAKMFLQVDKSWKEIMRKV NRLPNALRAATQPGLLETFQNNNALLDQIQKCLEAYLESKRVIFPRFYFLSNDELLEILA QTRNPQAVQPHLRKCFDSISKLEFALMPPTEGKIPGMEGEPEKIYTNDILAMLSPEGERV SLGKGLKARGNVEDWLGKVEEAMFTSLRRLCKAAIADYQGKPRTDWVIAGHPSQVILTIS QIMWCRDLTECLEREGGNHIEALEAFEEVNFERLNALAATVRGSLPKLHRNIITALITID VHARDIVTELVQAKVEEVDSFDWQRQLRYYWDIDQDNCVARMALSQYTYGYEYLGACPRL VITPLTDRCYLCLMGALQLDLGGAPAGPAGTGKTETTKDLAKALAIQCVVFNCSDGLDYK MMGRFFSGLAQSGAWCCFDEFNRIDIEVLSVIAQQLITIRNAKAAKLSRFMFEGREIKLV MTCAAFITMNPGYAGRTELPDNLKALFRPFAMMVPNYALIAEVILYSEGFESSKILARKM TQMYKLCSEQLSQQDHYDFGMRAVKSVLVMAGSLKRENPHLSEDVVLIRALRDSNLPKFL TDDAILFSGIISDLFPGVQIPEHDYGILQSTIIDVMNRKNLQPETCMVKKVIQFYETMLV RHGVMLVGPTGGGKTTVYQILAETLGNLQKLGLDNPFYQPVKTYVLNPKSITMGELYGEV NNITLEWKDGLMALSVRAAVSDTSEDHKWIISDGPVDALWIENMNTVLDDNKMLCLANSE RIKLTPQIHMLFEVQDLRVASPATVSRCGMVFVDPEELKWMPYVKTWMKNISKKLNEETQ EYILNLFQRYVDDGLYFVNKKCSQAIPQVDISKVTTLCCLLESLIFGKDGVNLTMEQIKL NTVLCQTFIFCYLWSLGGNLTENYWDSFDTFIRTQFDDNPDARLPSSGDLWSIHMDFDTK RLDPWERIIPTFKYSRDVPFFEMLVPTTDTVRFGYLMEKLLAVRHSVLFTGITGVGKSVI AKGLLNRIQESAAYVPVYLNFSAQTSSARTQEIIESKLERKRKNILGAPGNKQVVIFVDD LNMPRLDRYGSQPPIELLRQYQDFGGFYDRNKLFWKDIQDVTIVSACAPPGGGRNPVTPR FIRHFSMLCLPTPSEHSLKQIFQAILNGFLSDFPPAVKQTASNIVEAAVEIYNRMSVDLL PTPAKSHYIFNLRDLSKCVQGILQCDPGTVREEIQIFRLFCHECQRVFHDRLINNEDKHY FHAILTEMANKHFGIAIGLEYFLTKPIIFGDFIKFGADKTDRIYNDMPDMEKIANVLQDY LDDYNLINPKEVKLVFFQDAIEHVSRIARMIRQERGNALLVGVGGTGKQSLTRLAAHICG YKCLQIELSRGYNYDSFHEDLRKLYKLAGVDNKNMVFLFTDTQIVVEEFLEDINNILNSG EVPNLFEKDELEQVLAATRPRAKEVGISEGNRDEVFQHFISRVRQKLHIVLCMSPVGEAF RSRCRMFPSLVNCCTIDWFVQWPREALLSVSKTFFSSVDAGKEEMKEKLSLMCVNIHLSV SNMAERYYMELRRRYYTTPTSYLELINLFLSMLSEKKKQLVSARDRVKNGLTKLLETNVL VDKMKLELSALEPILFQKSQDVEALMEKLAVDQENADQVRSIVQEDEATAKVKAEETQAI ADDAQRDLEEALPALDAANKALDSLDKADISEIRVFTKPPDMVMTVMEAISILLNAKPDW PTAKQLLGDSNFLRRLLEYDKENIKPQILAKLQKYINNPDFVPEKVEKVSKACKSMCMWV RAMDLYSRVVKEVEPKRQKLRAAQAELDITMATLREKQALLKKVEDQIQALQDKYDKGVN EKESLAKTMALTKARLIRAGKLTAALEDEQVRWEESIQKFNEEISNIIGNVFIAAACVAY YGAFTAQYRQSLIEYWIQDCLSLEIPINPSFSLINILGDPYKIRQWNTDGLPRDMISTEN GILVTEGRRWPLMIDPQDQANRWIRNKESKSGLKIIKLTDTNFLRTLENSIRLGLPVLLE ELRETLDPALEPILLKQTFMSGGRLLIRLGDSDIDYDKNFRFYMTTKLPNPHYLPEVCIK VTIINFTVTKSGLEDQLLSDVVRLEKPELEEQRIKLIVRINTDKNQLKTIEEKILKMLFT SEGNILDNEELIDTLQDSKITSGAIKIRLKEAESTELMINVAREKYRPVATQGSVMYFVI ASLSEIDPMYQYSLKYFKQLFNTTIETSVKSDDLEQRMEILLEQTLLTAYVNVSRGLFEQ HKLIYSFMLCVEIMRQQESLTDAEWNFFLRGSAGLEKERPPKPEVPWLHNAMWFACCDLE ESFPVFKGLTQYILLHPISIQIGSFETYINPYEWEGYSKSKEEEEFMTEEKETKNRNSWH PVLSSFQKLLLIKCCKEEKIVFALTDFVIESLGKRFIETPPVDLPTLYQDMSYNTPLVFI LSTGSDPMGAFQRFARDSGYSERVQSISLGQGQGPIAERMIKDAMKSGNWVFLQNCHLAV SWMLAMEELIKTFTDPNIIIKDTFRLFLSSMPSSTFPVTVLQNSVKVTNEPPKGLRANIR RAFTEMTPSFFEENILGRKWRQIIFGICFFHAIIQERKKFGPLGWNICYEFNDSDRECAL LNLNLYCQEGNIPWDALIYITGEITYGGRVTDTWDQRCLRTVLKRFFSPETLEEDYKYSE SGIYFAPLADTLQEFKDYIENLPLIDDPEIFGMHENANLVFQYKETNTLINTILEVQPRS SSGGEGKSNDEIVRELVASVQIRVPETLEMESASESLFAKDSQGRLNSLTTVLGQEVDRF NQLLKLIHTSLETLNKAIAGLVVMSEEMEKVYNSFLNNQVPSLWSTTAYPSLKPLGSWVK DLILRTAFVDLWLKRGQPKSFWISGFFFPQGFLTGTLQNHARKHNLPIDELSFKYNMIPI YRDQAAVIEAAKTVQFGQELPMDLELPSPEDGVLVHGMFMDASRWDNTEMVIEDALPGQM NPMLPVVHFEPQQNYVPSPTLYHSPLYKTGARAGTLSTTGHSTNFVVTVLLPSKRSKDYW IAKGSALLCQLNE NT seq 12462 nt NT seq  +upstreamnt  +downstreamnt atggcattccacacctcagcgaaagatgccaaactgaaaaatactgaaaagcaggtggaa aaccctatccttgaaagactgaacaatatacaaaaaaagggaagactgagttttatagta cccacagaaaatgaatctgacacacaattcctgacgtttagacacagtacaaaagctcaa gagagaacaagaaaacgacagcagcccataagactagagcctctgccagtgctaaaagtc taccaagatcataagaggccagaatacatatatgaacagaaccgacttcagttaatctct tctggaatcataaaacctccaggaagcactgaagaaagaagttctaccaaattatctgtt cagtttcttgagcctcaatatactgtgaggaagaaaaaacagcagccctctgctgagatg ttctctccctctcctcctaaactgtcacgtaccagtattggaagaagaggtctctatggg accagttcctcagcgtaccctaagtactttttccatgatcgggaagaagtcgttaaagcc aacgtttgtaatcctttgcaaatcattaaaataatacgtgaaaatgaacacctcggattt ctttatatgatccctgcagtgccaaggtcttccactgaatatgatacatataatctcaaa gttgtaagttatgagaacatcaataaaaatgactactatactattagcaaaaaagccata acacacatttataatgaggacattgagtatatcgaaattgatcgatgggaacaggagtat ctatatcacagagaactcactaagattcccatatttgcacttttccggaaatggaaggct tttaatgtgtggaagaagaatgtccgttccaagaaaatcagtggttgtcgacaatctcta caaaaaaatttgttcattgttaatcctcatttgcgaccggctcttcttaaaataaatgaa ttatgctataacttgagttttatcagactttgttatattgaaaaatgtcatacttatacc ctgcaagaatttaagaccacacaaatcatatggttagaagaggtgacaatgcgcctagaa gaatttcgaaatgaggcaaaagttgtggtcaggaaggcttgtcgaattgctctgcatgcc gcaggatttattcctgatgactgtcaacataaacctgttgaggattattgtaaaatgcca gatggtgaaggtctcactgagttgcctgcttattcagactctgagaaaatgacatacaca gagcaggccagcaaaaggcatcactgcatgaggctaacatgctttatccgtctaaatgac tatctaattgagaacacaatgcacatcctaacagtaaattctgttaactctcttttgaat tatctcactgacaagctaaagcgaacaccttcagaagatgtcattcagaaatggattact gaagagaagcctcacgtcactgataaaaagggggcctctgtggtggaaaagcaggaagaa gatgagtctctcatccctatgtttctcacagaactgattttgacagtccaatcattactc ttcgagccttctttggaagacttcctggctggtatttcagatgcaattaatcaatttcaa aacactgtgctatcagttcctaatcttgtacctgatacatattttgacgcttttaccaga ccttacattaacaacaaacttgaagaaaaaacttgtggatttggtccaagcctatcagca gtatttgatgatgataagaattttcacacaattatccttcaaataaaggaaaccatacaa gcagcatttgaatctgcccgattatatgcagctacgtttgaaaagttccatatattcttc aaggaaaatgaaagtcttgatttacaagctcttaaacttcaagaacctgatgttaagttt tttggagaacaactggaaaaataccacagacagcacaaggacgcaatagctctaagaccc accagaaatgtaggattgctgctcattgatacaaagctgctaaaagaaaaactaattcca tcacctttgcgatgcttggaggtgctaaattatatgcttcctcgtcaaagcaagaaaaaa gtggatgccattatctctgaggcacaagatgcagagtataaacttgaatttgttccaact accaccatagaatatgttaacagcttagtgtttcttgatgaaattcaggaaaggatcgaa agccttgaagatgaagggaatgtagtgattcaaatgtacaagctcattgaacagtatcag gttcccacacctcctgaagactttgctgttttcgctactatgaagccatccattgttgca gttcggaatgccattgataaatctgtgggtgacagagaaacaagcattaagcagttttct ctgcatttgggtagagatcttgaagacctagccaatgaagtgaatgaagtaaagctacac gcacaggatccacagatcttagatattactgctgaccaagacaaaataaagctcatgttg cacgatctgcagttggttctagatgatcttcaaaaacgtgcatttcaatataaatcctat cagaagaattttaagatagaagtatccaagtttgaagctttggaagaagttagtgctgag ttgaagctcaaacaattgctctgggattctttatctgaatgggatcaactccaacaagaa tggttaaagtccaaatttgacggcctggatccagaagtcctaaatagtcaagtttctaaa tatgccaaatttgtgactcaattggaaaaaggcttgccacccaacagtgtagttcctcag ctaaaatgtaaggtggaaaaaatgaaagaaaagcttccagttatcattgacttgaggaat ccaactttgaagccaagacattgggcagctattgaacaaacagttgacgccaccctagtg gaccttgacattccattaaccttggagaagctctctgagttgcatgttttcgattttggc caagaaatccaggacatttctggacaggcttctggagaagctgccttagaaataattctt aaaaaggtggaagattcttggaaaacaactgaatttgtcgttctccctcaccgtgactcc aaagatgtgtttatcctgggcggcacagatgacatacaggtccttcttgatgacagcacc atcaacattgcaaccattgcctcatcacgttacgttggtccactgaaaactcgagtggat gactggcagaaacaacttgctttatttaatcaaacactggaagagtggctgaactgtcag cgaaactggctctacctagaaagtatttttaatgctccagatattcagaggcaattgcct gccgaggctaagatgttccttcaagtggataagtcatggaaggaaatcatgaggaaggtg aaccggttgcctaatgctcttcgagccgctactcaaccaggacttctggagacttttcaa aataataatgcattacttgaccaaattcaaaagtgtctagaggcatatttagaatcaaaa agagttatctttccaagattttacttcttgtcaaatgatgaacttctggagattctggcc cagacacgaaatccccaagctgtgcagccacacttaaggaaatgctttgactccatttca aagctcgaatttgctctcatgcctcctactgaaggaaaaattcctggtatggaaggagag ccagaaaagatttacactaatgatattttagcaatgctatcaccagaaggagaacgggtt agcttgggaaaaggcctcaaagcccgaggcaacgtggaggattggcttggtaaagtggaa gaagccatgttcacatctctgcgtcgcctttgcaaagccgccatcgctgactaccagggg aaaccaaggacagactgggtgattgctggccacccttctcaagtgattctgaccatttct caaatcatgtggtgccgtgatttgactgagtgcttggaaagagaaggtggtaatcatata gaggccctggaagcttttgaagaagtaaactttgagagattaaatgccctggcagcaaca gttcgaggcagtcttccaaaattacacagaaacatcataactgccttaattactattgat gtacatgcaagagacatagtcaccgaacttgttcaagccaaggtagaggaagtggattcc tttgactggcagagacaactgcgctactattgggacatagatcaggataattgcgtggct cggatggcgctctctcagtacacctatggctacgagtatttgggtgcatgcccaagacta gtcattactcctctcacagatcgctgttacctttgcctcatgggggctttgcagcttgac ctgggaggtgcaccagctggtcctgctggcactgggaaaacagagacaaccaaagaccta gctaaagctcttgccatccagtgtgtggtcttcaactgctccgatggtttggactacaag atgatggggcgcttcttcagcggtctggcccaatcaggggcctggtgctgctttgatgaa tttaatcgaatcgacatagaagttttgtcggtcatcgcacagcagctcattactattagg aatgccaaagctgcaaagctatctagattcatgtttgagggccgggaaataaagttggtt atgacttgtgcagcttttatcacaatgaatcctggatacgcaggcagaactgaattgcca gataatttgaaggccctgtttagaccctttgcaatgatggttccaaattatgctttgatt gcagaggtaattctatattctgaaggatttgaatccagtaaaatattagccagaaaaatg actcagatgtataagctttgcagtgaacagctctctcagcaagatcactacgactttggc atgagagctgtgaagtctgtactggtcatggctgggtccttaaaaagggagaatccacac ttaagtgaagatgtggtattgataagagctttacgagactccaacttgccaaaattccta acagatgatgctattctgttcagtggaattatatctgacctttttcctggagtccaaatt ccagaacatgattatggtatattgcagtcaacaattatagatgtcatgaatagaaaaaat cttcagcctgagacatgtatggttaaaaaagtgatacagttctatgaaactatgctggta agacacggtgttatgttagtcgggccgacaggaggtggcaagaccacagtttaccaaata ctagcagaaactttagggaatttgcaaaaacttggtttagacaatcccttttaccaaccg gttaaaacatacgttcttaatcctaaatcaattacaatgggtgaattatatggtgaagtt aataacataaccttggagtggaaagatggtttgatggcactaagtgtccgagcagctgtg agtgacacttcagaagaccataaatggatcatcagtgatgggcccgtggatgctctttgg attgaaaatatgaatacagtgctggatgataacaagatgctttgcctggctaacagtgag aggatcaaactcacacctcaaatccacatgctttttgaggtgcaagacctaagagttgcc tctcctgcaacagtcagtcgatgtggaatggtgtttgtggatcctgaagaactgaaatgg atgccttatgttaaaacatggatgaagaatatttctaaaaaactaaatgaggaaacccaa gaatacatattgaaccttttccaacgttatgttgatgatggtttatattttgtcaataaa aaatgcagccaagcaatcccacaagtggacatcagcaaagttactacactctgttgctta ttggagtctttgatatttgggaaagatggagttaatttgacaatggaacaaataaaactg aatacagtactatgtcagacttttatattctgttatttatggtctttgggtggaaatcta actgaaaactactgggattcctttgatacatttattagaacacaatttgatgataatcct gatgccaggcttcccagttctggtgatctgtggagcattcatatggacttcgacaccaaa cgactggatccctgggaacgaatcatacccacctttaagtacagccgagatgttcctttt tttgaaatgctagtccccacaactgacacggtgcgctttggatatctaatggaaaaacta ctggcagtcaggcattcagtgctgtttactggaataactggagttggcaagtctgtcatt gcaaaaggattgttgaatcgaattcaagaatcagctgcctatgttcctgtttatctaaac ttttctgctcaaacttcatctgcaagaacacaagagatcattgagtcaaaactggaaagg aaaagaaaaaatatactaggagcaccaggaaacaaacaagttgtgatttttgttgatgat ttaaacatgcccagactggaccgctatggctctcagcctccaattgaattacttcggcag tatcaagattttggtggattttatgacagaaacaaactcttttggaaagacatacaggat gtaacgatcgtctcagcatgtgcacctccaggtggtggccgcaaccctgtgactccccgt tttatccgacacttcagcatgctgtgccttccgacgccctcagagcacagtctgaaacag atttttcaggccatcttaaatggcttcctcagtgacttcccaccagctgtaaagcaaacc gcatcaaacattgtagaggctgcagttgagatttataacagaatgagtgttgatcttctg ccaacaccagccaagtcccattacatctttaacttgagggatttatccaaatgtgtacaa ggtatcctccaatgtgatccaggaacagtaagagaagaaatacagatatttagactcttt tgccatgaatgccaaagagtcttccatgaccgtttgattaataatgaagataagcactat ttccatgctattttgacagaaatggccaacaaacattttggaattgcaattggcctggaa tattttttgacaaaacccatcatctttggagactttattaagtttggagcagataagact gatcggatttacaatgacatgcctgatatggagaaaatcgcaaatgttctacaggactat cttgacgattataaccttataaatcccaaagaagtaaagttggtgttcttccaggatgct atagaacatgtttcaaggattgcccgcatgattcgtcaggaaagaggcaatgcgctgctc gttggagtaggaggcactggaaaacagtctcttacaagacttgcagctcacatatgtggt tacaaatgtttgcaaattgaactgagccgaggatataattatgacagttttcatgaagac ctgaggaagttgtacaaactggctggtgtggataacaagaatatggtcttcctcttcact gacacccagattgtagtagaagaattcctagaagatataaataacatcctgaactctggt gaagtgcccaatttatttgaaaaggatgaactggaacaggttttagcagccaccagacca cgagcaaaagaagtaggaatttccgaggggaatagagatgaggtgtttcagcactttatc agcagagtccgtcagaagctgcacatcgttctctgtatgagccctgtgggggaggccttc cggtcccggtgccgaatgttcccatcccttgtgaactgctgcactattgattggtttgtc cagtggcctagagaagcacttctttctgtatcaaagacatttttctccagcgttgatgct ggaaaagaagaaatgaaagaaaagctttccctcatgtgtgtgaacattcacttgagcgtc tccaatatggcagaacgctattacatggagctccggagacggtactacacaacacccacc tcctacctggaactcatcaatcttttcctgagtatgctgagtgaaaaaaagaagcagttg gtttcagcacgtgaccgggtgaagaatggtctcaccaagctattagaaaccaatgttcta gtagataaaatgaaattagagctttcagctttagagcctatcctttttcaaaaatcacaa gatgttgaagccctgatggaaaaattggcagtggatcaagaaaatgccgatcaggtccgt agcattgtgcaagaagatgaagcgacggcaaaagtgaaagctgaagagacccaagcaata gctgatgatgctcaaagagaccttgaagaagctctgcctgcacttgatgctgctaataaa gcactggattccttagataaagcagatatatctgagatcagagtttttacaaagccccca gatatggtcatgactgttatggaagcaatttctattctcttgaatgccaaacctgattgg ccaacagcaaagcaacttcttggtgactctaactttctaagaagacttctagaatatgat aaggaaaatataaagcctcagatattggcaaaacttcagaagtatattaacaatcctgat tttgtgcctgaaaaagtagagaaagtgtccaaagcatgtaaatccatgtgcatgtgggta agagcgatggatctatactctagggtagtcaaagaagtcgaaccgaagagacaaaaactc cgtgctgcgcaggctgaacttgatatcacaatggctactctgagagaaaagcaagccttg ctaaaaaaagtggaagatcaaatacaggccttacaagacaaatatgacaaaggggtgaac gagaaagaaagtctggcaaaaactatggccctgacaaaagcacgtctgatacgtgcagga aagctgacggctgcactagaagatgagcaagttcgatgggaagaaagcatccagaaattc aatgaggagatatcaaatatcattgggaatgtgtttatagcagcagcttgtgtagcctat tatggggccttcacagcccagtataggcaatcgcttatagaatactggatccaggactgt ctgtctctggagatcccaatcaatccttccttcagtctcattaacattcttggtgatccc tacaaaatacggcagtggaacactgatgggctgccccgtgacatgatatcaacagaaaat ggcattttggttactgaagggagacgatggcctttgatgattgacccccaggatcaggca aaccgttggataaggaacaaggaaagcaaaagtggtttaaagatcattaagcttacggat actaatttcttgcgtacacttgaaaattcaatccgacttggtttacctgtcttactggaa gagcttagagaaaccttggatccagctctagaacccattcttttgaagcagactttcatg agtggtgggcggctgctcattcgcctcggagactcagacattgactacgacaaaaacttc aggttctacatgacaaccaaactgccaaatccccactacctgcccgaggtgtgcattaaa gtcaccatcatcaatttcactgtaaccaaatcaggtctggaggatcagctgttaagtgat gtggtacgacttgagaaacccgagttggaagaacaaagaatcaagctcattgtgagaata aacactgataaaaaccagctgaaaactatcgaagagaaaatcctgaaaatgctctttaca tctgaaggaaatattctggacaatgaagaacttattgacacactccaggattcaaagatc acttcaggtgccattaaaatcaggctaaaggaagctgagtccactgaactgatgataaat gttgctcgtgagaagtatcgtccagtagccactcaaggctctgttatgtacttcgttatt gcaagcctctcagaaatagatcctatgtatcagtattcattaaaatattttaaacagttg ttcaatacaacaattgaaacatctgtaaagtcagacgatctagagcagcgcatggaaata ctcctggaacaaacccttctaaccgcttacgtcaatgtttccagaggactctttgagcaa cataaactcatctacagctttatgctgtgtgtagagatcatgcgtcagcaagaaagccta actgatgccgagtggaatttctttctccgaggttctgcaggattagaaaaggaacgccca cctaagcctgaagttccctggctgcataatgccatgtggttcgcatgctgtgacttagaa gaatcatttccagtttttaaaggacttacacaatacatactgttacatcctatttccata caaataggatcctttgagacttatatcaatccatatgaatgggaaggctattctaaaagt aaggaggaagaagaattcatgacagaagaaaaagagaccaaaaaccgtaattcctggcat ccagtattgagttctttccaaaagctacttctcattaaatgttgcaaagaagagaagata gtttttgctcttacagactttgtaatagaaagtcttggaaaacgctttatagagacaccc cctgtggacctgcccactctgtatcaagacatgtcgtataacactcccctggtattcatc ttaagcacaggctcggatcctatgggggcattccagaggtttgcccgggacagcgggtat tcagaacgggtgcaatcaatttcactggggcaaggacaaggacccattgctgaaagaatg atcaaagatgcgatgaaatcaggaaactgggtgtttttgcagaactgccatcttgctgtt tcttggatgttggcaatggaagaactaattaaaaccttcacagatccaaacattatcatc aaggacacttttcgactttttttaagttccatgcctagtagtacatttcctgttacagtt ctccaaaattctgtcaaggtaaccaatgagcctccaaaaggtttacgtgcaaatatcaga cgagcatttactgaaatgacaccttcgttttttgaagaaaatatactcggaagaaaatgg agacaaataatatttggcatttgtttcttccatgcaattattcaggagagaaaaaagttt ggccctcttggttggaatatctgctatgaatttaatgacagtgacagggaatgtgctttg ctgaacctcaacctttattgtcaagaaggaaatattccctgggatgcattgatttacatt actggtgaaattacatatggtggtagagttacagacacctgggatcaaagatgccttcgg actgtcttaaaaaggtttttttctcctgaaacattagaagaggattacaaatattctgaa tcaggcatctattttgcaccattggctgataccctacaagagtttaaagactacattgaa aatctgcctttaatagatgatccagaaatatttggaatgcatgaaaatgccaacctagtt ttccagtacaaagagaccaacactttaatcaacaccatacttgaggttcagccaaggtca tcttctggtggagagggaaaaagcaatgatgaaattgtccgagaacttgttgcttcagtc cagatcagagttccagaaacactagaaatggagagtgcatctgagagccttttcgccaag gattcccaaggacgccttaactctttgactaccgttctcggacaagaagtggaccgcttt aatcagctattgaagttaatacatacttctctggagacactcaacaaagctattgctggc cttgtggtgatgtctgaggaaatggagaaggtgtacaacagtttcctcaacaaccaagtt ccctctctatggtccaccacagcctacccatccctgaagccactaggatcgtgggtcaaa gacctgatcctgaggactgcatttgtggatttgtggctcaaaagagggcagcctaagtcc ttctggatctccggtttcttctttcctcaaggatttctaacaggaactcttcaaaatcat gctcggaaacacaatttgcctatagacgagctgagtttcaagtacaacatgattcctatc tatcgggatcaagctgcagttatagaagctgccaagacagtgcagtttggacaagaactg cccatggacttggagttgccctctcccgaagatggtgttcttgttcatggaatgtttatg gatgcttctcgatgggacaatacagagatggtgatagaagatgcactgccaggacagatg aatccaatgctgcctgtggtgcattttgaacctcaacaaaattacgtgccaagcccaaca ctttaccattccccactttataaaacgggggcccgggcaggaacactctcaaccacaggt cattccaccaactttgtggtaactgtgctcttaccctccaagcggtccaaagattactgg attgccaaggggtcagctttgctctgccaactaaatgagtga

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