Puma concolor (puma): 112869732
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Entry
112869732 CDS
T08890
Symbol
NDUFS1
Name
(RefSeq) NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial isoform X1
KO
K03934
NADH dehydrogenase (ubiquinone) Fe-S protein 1 [EC:
7.1.1.2
]
Organism
pcoo
Puma concolor (puma)
Pathway
pcoo00190
Oxidative phosphorylation
pcoo01100
Metabolic pathways
pcoo04714
Thermogenesis
pcoo04723
Retrograde endocannabinoid signaling
pcoo04932
Non-alcoholic fatty liver disease
pcoo05010
Alzheimer disease
pcoo05012
Parkinson disease
pcoo05014
Amyotrophic lateral sclerosis
pcoo05016
Huntington disease
pcoo05020
Prion disease
pcoo05022
Pathways of neurodegeneration - multiple diseases
pcoo05208
Chemical carcinogenesis - reactive oxygen species
pcoo05415
Diabetic cardiomyopathy
Module
pcoo_M00143
NADH dehydrogenase (ubiquinone) Fe-S protein/flavoprotein complex, mitochondria
Brite
KEGG Orthology (KO) [BR:
pcoo00001
]
09100 Metabolism
09102 Energy metabolism
00190 Oxidative phosphorylation
112869732 (NDUFS1)
09150 Organismal Systems
09156 Nervous system
04723 Retrograde endocannabinoid signaling
112869732 (NDUFS1)
09159 Environmental adaptation
04714 Thermogenesis
112869732 (NDUFS1)
09160 Human Diseases
09161 Cancer: overview
05208 Chemical carcinogenesis - reactive oxygen species
112869732 (NDUFS1)
09164 Neurodegenerative disease
05010 Alzheimer disease
112869732 (NDUFS1)
05012 Parkinson disease
112869732 (NDUFS1)
05014 Amyotrophic lateral sclerosis
112869732 (NDUFS1)
05016 Huntington disease
112869732 (NDUFS1)
05020 Prion disease
112869732 (NDUFS1)
05022 Pathways of neurodegeneration - multiple diseases
112869732 (NDUFS1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
112869732 (NDUFS1)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
112869732 (NDUFS1)
Enzymes [BR:
pcoo01000
]
7. Translocases
7.1 Catalysing the translocation of protons
7.1.1 Linked to oxidoreductase reactions
7.1.1.2 NADH:ubiquinone reductase (H+-translocating)
112869732 (NDUFS1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Molybdopterin
Fer2_4
NADH-G_4Fe-4S_3
NADH_dhqG_C
Fer2
Motif
Other DBs
NCBI-GeneID:
112869732
NCBI-ProteinID:
XP_025788639
UniProt:
A0A6P6ILD5
LinkDB
All DBs
Position
Unknown
AA seq
727 aa
AA seq
DB search
MLRIPLKRALVGLSKSHKGCVRTTATAASNLIEVFVDGQSVMVEPGTTVLQACEKVGMQI
PRFCYHERLSVAGNCRMCLVEIEKAPKVVAACAMPVMKGCNILTNSEKSKKAREGVMEFL
LANHPLDCPICDQGGECDLQDQSMMFGNDRSRFLDGKRAVEDKNIGPLVKTIMTRCIQCT
RCIRFASEIAGVDDLGTTGRGNDMQVGTYIEKMFMSELSGNIIDICPVGALTSKPYAFTA
RPWETRKTESIDVMDAVGSNIVVSTRTGEVMRILPRMHEDINEEWISDKTRFAYDGLKRQ
RLTEPMIRNEKGLLTYTSWEDALSRVAGMLQSVQGKDVAAIAGGLVDAEALVALKDLLNR
VDSDTLCTEEVFPTAGAGTDLRSNYLLNTTIAGVEEADVLLLVGTNPRFEAPLFNARIRK
SWLHNDLKVALIGSSVDLTYRYDHLGDSPKILQEIALGNHPFSQVLHEAKKPMVVLGSSA
LQRNDGAAILAAVSNIAQKIRTSSDVTSDWKVMNILHRIASQVAALDLGYKPGVEAIRKS
PPKVLFLLGADGGCITRQDLPKDCFIIYQGHHGDIGAPIADVILPGAAYTEKSATYVNTE
GRAQQTRVAVTLPGLAREDWKIIRALSEIAGMTLPYDTLDQVRNRLEEVSPNLVRYDDVE
GANYFQQANELSKLVNQQLLADPLVPPQLTIKDFYMTDSISRASQTMAKCVKAVTEGAQA
VEEPSVC
NT seq
2184 nt
NT seq
+upstream
nt +downstream
nt
atgttaaggatacctctaaaaagggccttagtaggcctgtctaagtctcataaaggatgt
gttcgaacaactgccacagcagcaagcaacttaattgaagtatttgtcgacggtcagtct
gtcatggtggaaccaggaactaccgtactccaagcttgtgagaaggttggcatgcagatc
cctcgattctgttatcatgaaagattgtctgttgctggaaactgtaggatgtgccttgtt
gaaattgagaaagctcctaaggttgtggcggcttgtgccatgccagtaatgaaaggttgt
aatatcctgacaaactcagagaaatctaagaaagcaagagaaggtgtgatggagttcttg
ttagcaaatcacccactggactgtcctatttgtgaccagggaggtgaatgtgatctgcag
gaccagtccatgatgtttggaaatgataggagcagatttttagatgggaaacgtgctgtg
gaggacaagaatattgggccattggtaaagactatcatgactagatgtatacagtgtact
cgctgcatcaggtttgcaagtgagattgcaggagtagatgatttgggaacaacaggcaga
ggaaatgatatgcaagttggcacgtacattgaaaagatgttcatgtctgaactgtctgga
aatatcattgatatctgccctgtaggtgccctgacttcgaagccctatgcttttactgcc
cgcccttgggaaacaagaaagacggaatccattgatgtaatggatgcagttggaagtaat
attgtggtaagcacaagaactggagaggtgatgcggattttgccaaggatgcatgaggat
atcaatgaagagtggatctctgataaaaccagatttgcctatgatgggctaaaacgtcaa
agactaaccgagccaatgatcagaaacgaaaaggggcttttaacctacacttcctgggaa
gatgcactctctcgtgtagctggaatgttgcagagtgttcaaggcaaggatgtggcagca
attgcaggtggcttggtggatgctgaagccctggtagctctcaaagatttgcttaataga
gtggactctgacaccttgtgcactgaagaggtcttccccactgcaggagctggcacagat
ttgcgttctaattatcttcttaatactacaattgctggtgtggaagaggcagatgttctc
cttctggttggtacaaatccgcgttttgaggcaccactgtttaatgctagaattcgaaag
agctggcttcataatgacttaaaagtggcccttattggcagctcagtggatctcacttac
agatatgaccatctgggagattcccccaaaattcttcaggagattgctttgggtaaccat
ccattcagccaggtattacatgaagctaaaaaaccaatggtggttttaggcagttctgca
ctccaaagaaatgatggggcagcaattcttgcagctgtttccaacattgctcaaaagatt
cggacgagtagtgatgttaccagtgattggaaagttatgaatatccttcataggattgca
agccaagtagctgctttggaccttggctataaacctggggtggaagcaattcgtaagagc
cctcccaaagtgctatttctcctgggagcagatggaggttgtatcactcgacaggatttg
ccaaaggattgtttcattatttatcaaggacatcatggagacattggagctccaatagct
gatgttattctcccaggcgctgcttacacagaaaagtcagccacttatgtcaatactgaa
ggccgagctcagcagacaagagtagcagtgacacttcctggcttggcaagagaagactgg
aaaattataagagccctctctgagattgcaggtatgactcttccatatgatactctggat
caagtaaggaacagattggaggaagtctctcctaatcttgtccgatatgatgatgtcgaa
ggagccaattatttccagcaagcaaatgagctctccaagctagtgaaccagcaacttctt
gctgatccgcttgttccacctcagctaacaataaaagacttctacatgacagactcaatt
agcagagcctcacagacaatggccaaatgtgtcaaagctgtcacagaaggtgcccaagca
gtagaggagccatctgtttgctga
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