Puma concolor (puma): 112870381
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Entry
112870381 CDS
T08890
Symbol
PDE11A
Name
(RefSeq) dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A
KO
K13298
dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11 [EC:
3.1.4.17
3.1.4.35
]
Organism
pcoo
Puma concolor (puma)
Pathway
pcoo00230
Purine metabolism
pcoo01100
Metabolic pathways
pcoo04934
Cushing syndrome
pcoo05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
pcoo00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
112870381 (PDE11A)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
112870381 (PDE11A)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
112870381 (PDE11A)
Enzymes [BR:
pcoo01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.17 3',5'-cyclic-nucleotide phosphodiesterase
112870381 (PDE11A)
3.1.4.35 3',5'-cyclic-GMP phosphodiesterase
112870381 (PDE11A)
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SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PDEase_I
GAF
GAF_3
HD-CE
HD
Motif
Other DBs
NCBI-GeneID:
112870381
NCBI-ProteinID:
XP_025789326
UniProt:
A0A6P6IM43
LinkDB
All DBs
Position
Unknown
AA seq
933 aa
AA seq
DB search
MTASHLDFGEVETFLDRHPELFEDYLMRKGKQEMVEKWLQRHSESQGAVGPRPAVASTNS
LAHSGGRRSGSVGVGPGPNSSANSQPTLGGGDCGGVPLSPSWASGSGGDGSLQRRASQKE
LRKSFARSKAIHVNRTYDEQVTSRAQEPLSSVRRRALLRKASSLPPTTAHILSALLESRV
NLPQYPPTAMDYKCHLKKHNERQFFLELVKDISNDLDLTSLSYKILIFVCLMVDADRCSL
FLVEGAAAGKKSLVSKFFDVHAGTPLLPCSSTENSNEVQVPWGKGIIGYVGEHGETVNIP
DAYQDRRFNDEIDKLTGYKTKSLLCMPIRSSDGEIIGVAQAINKIPEGAPFTEDDEKVMQ
MYLPFCGIAISNAQLFAASRKEYERSRALLEVVNDLFEEQTDLEKIVKKIMHRAQTLLKC
ERCSVLLLEDIESPVVKFTKSFELMSPKCSADAENSFKESMEKSSYSDWLINNSVAELVA
STGLPVNISDAYQDPRFDAEADQISGFHIRSVLCVPIWNSNHQIIGVAQVLNRLDGKAFD
DADQRLFEAFVIFCGLGINNTIMYDQVKKSWAKQSVALDVLSYHATCSKAEVDKFKAANI
PLVSELAIDDIHFDDFSLDVDAMITAALRMFMELGMVQKFKIDYETLCRWLLTVRKNYRM
VLYHNWRHAFNVCQLMFAMLTTAGFQEILTEVEILAVIVGCLCHDLDHRGTNNAFQAKSG
SALAQLYGTSATLEHHHFNHAVMILQSEGHNIFANLSSKEYSDLMQLLKQSILATDLTLY
FERRTEFFELVSKGEYDWNIKNHRDIFRSMLMTACDLGAVTKPWEISRQVAELVTSEFFE
QGDRERSELKLTPSAIFDRNRKDELPRLQLEWIDSICMPLYQALVKVNVKLKPMLDSVAA
NRSKWEELHQKRLLVPAASPSSASLVAAGEDRN
NT seq
2802 nt
NT seq
+upstream
nt +downstream
nt
atgacggcctcacacctggactttggggaagtggaaactttcctggacagacacccagag
ttatttgaagattacctgatgcggaaggggaagcaggagatggtggagaagtggctgcag
agacacagtgagagtcagggggctgtaggcccgaggcccgcagtggccagcaccaacagc
ttggctcacagcggtggcagacgcagcggcagtgttggtgttggccctggaccaaatagc
tctgccaacagccagcccactctgggcggcggggactgtggtggggttcccctgagtccc
agctgggccagtggcagcgggggcgatgggagcctgcagcggagagcttctcagaaagag
ctaaggaagagttttgctcgctccaaggccatccacgtgaacaggacctacgatgaacag
gtgacctcccgggcccaggagcccctgagcagtgtgcggcggagggcacttctccggaag
gccagctccctgccccccaccacagcccacattctcagtgccctgctggaatccagggtg
aatctgcctcagtacccccctacggccatggactacaagtgccacctcaaaaagcataat
gagcgtcagttcttcctggaactggtcaaggatatctccaatgaccttgaccttaccagc
ctgagctacaagatcctcatctttgtctgcctcatggtggacgctgaccgctgctctctc
ttcctggtggaaggggcagctgctggcaagaagagcttggtctccaaattctttgatgtg
catgcaggaaccccactgctgccctgcagcagcacagagaactcaaacgaagtgcaggtc
ccctggggcaaaggcattattggctatgtcggggagcatggagaaacggtcaacattcct
gatgcctaccaggatcgaagattcaatgatgaaattgataaactaactggatacaagaca
aaatcactcttgtgcatgcctatccgaagcagcgatggtgagattattggtgtggcccag
gcgataaataagattcctgaaggtgctccatttacagaagatgatgaaaaagttatgcag
atgtatcttccattttgtggaattgccatatctaatgctcagctatttgctgcctcaagg
aaagagtatgaaagaagcagggctttgctagaggttgttaatgacctatttgaagaacag
actgacctggagaaaattgtcaagaaaataatgcatcgggcccaaactctgttgaaatgt
gaacgctgttctgttttactcctggaggacattgaatcaccagtggtgaagtttaccaaa
tcctttgaactgatgtccccaaagtgcagcgctgatgctgagaacagtttcaaagagagc
atggagaaatcctcatattccgactggcttataaataacagtgttgctgagctagtggct
tccacaggcctcccggtgaacatcagcgatgcctaccaggatcctcgctttgatgccgag
gctgaccagatatctggttttcacataagatctgttctctgtgtccctatttggaatagc
aaccaccaaataattggagtggctcaggtgttaaatagacttgatgggaaagcttttgat
gacgcagatcaacgactttttgaggcttttgtcatcttctgtggccttggcatcaacaac
acaattatgtatgatcaagtgaagaagtcctgggccaaacagtctgtggctcttgatgtg
ctgtcataccatgcaacatgttcaaaagctgaagttgacaagtttaaggcagccaacatc
cctctggtgtcagaacttgccatcgatgacatacattttgatgacttttctcttgatgtt
gacgccatgatcacagctgccctgcggatgttcatggagctggggatggtacagaaattt
aaaattgactatgagacactatgtaggtggctcttgacagtgaggaaaaattatcgaatg
gttctgtaccacaactggagacacgccttcaatgtgtgccagctgatgtttgcaatgtta
acaaccgcagggtttcaagagattctgaccgaggtggaaattttagcagtgattgtggga
tgcctgtgtcatgacctcgaccacaggggaaccaacaatgccttccaagctaagagcggc
tctgccctggcccaactgtatggaacttctgctaccctggagcatcaccattttaaccat
gctgtgatgatccttcaaagtgagggtcacaacatctttgctaatttgtcctccaaggaa
tatagtgaccttatgcagcttttgaagcagtcaatattagcaacagacctcacgctgtac
tttgagaggagaactgaattctttgaacttgtcagtaaaggagaatatgattggaacatc
aaaaaccatcgtgatatatttcgatcaatgttaatgacagcctgtgaccttggagccgtg
accaaaccatgggagatctcgagacaggtggctgaacttgtaaccagtgagttctttgaa
caaggagatcgggagagatcagaactcaaactcactccttcagctatctttgaccggaac
cggaaagatgaactgcctcggttacaattggagtggattgatagcatctgtatgcctttg
tatcaggcgttggtgaaggtcaacgtgaaactgaagcccatgctggactcggtggcagcg
aacagaagtaagtgggaagagctgcaccagaaaaggctgctggtgccagccgcctcaccc
tcgtctgccagcctcgtggccgctggggaagacaggaactaa
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