Puma concolor (puma): 112870473 Help Entry 112870473         CDS       T08890                                  Symbol NOS1 Name (RefSeq) nitric oxide synthase, brain   KO K13240   nitric-oxide synthase, brain [EC:1.14.13.39] Organism pcoo  Puma concolor (puma) Pathway pcoo00220   Arginine biosynthesis pcoo00330   Arginine and proline metabolism pcoo01100   Metabolic pathways pcoo04020   Calcium signaling pathway pcoo04145   Phagosome pcoo04371   Apelin signaling pathway pcoo04713   Circadian entrainment pcoo04730   Long-term depression pcoo04926   Relaxin signaling pathway pcoo04970   Salivary secretion pcoo05010   Alzheimer disease pcoo05014   Amyotrophic lateral sclerosis pcoo05022   Pathways of neurodegeneration - multiple diseases pcoo05410   Hypertrophic cardiomyopathy pcoo05412   Arrhythmogenic right ventricular cardiomyopathy pcoo05414   Dilated cardiomyopathy pcoo05416   Viral myocarditis Brite KEGG Orthology (KO) [BR:pcoo00001]  09100 Metabolism   09105 Amino acid metabolism    00220 Arginine biosynthesis     112870473 (NOS1)    00330 Arginine and proline metabolism     112870473 (NOS1)  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     112870473 (NOS1)    04020 Calcium signaling pathway     112870473 (NOS1)  09140 Cellular Processes   09141 Transport and catabolism    04145 Phagosome     112870473 (NOS1)  09150 Organismal Systems   09152 Endocrine system    04926 Relaxin signaling pathway     112870473 (NOS1)   09154 Digestive system    04970 Salivary secretion     112870473 (NOS1)   09156 Nervous system    04730 Long-term depression     112870473 (NOS1)   09159 Environmental adaptation    04713 Circadian entrainment     112870473 (NOS1)  09160 Human Diseases   09164 Neurodegenerative disease    05010 Alzheimer disease     112870473 (NOS1)    05014 Amyotrophic lateral sclerosis     112870473 (NOS1)    05022 Pathways of neurodegeneration - multiple diseases     112870473 (NOS1)   09166 Cardiovascular disease    05410 Hypertrophic cardiomyopathy     112870473 (NOS1)    05412 Arrhythmogenic right ventricular cardiomyopathy     112870473 (NOS1)    05414 Dilated cardiomyopathy     112870473 (NOS1)    05416 Viral myocarditis     112870473 (NOS1) Enzymes [BR:pcoo01000]  1. Oxidoreductases   1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen    1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor     1.14.13.39  nitric-oxide synthase (NADPH)      112870473 (NOS1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  NO_synthase FAD_binding_1 Flavodoxin_1 NAD_binding_1 PDZ PDZ_6 PDZ_2 Motif Other DBs NCBI-GeneID:  112870473 NCBI-ProteinID:  XP_025789403 UniProt:  A0A6P6IR91 LinkDB All DBs Position Unknown AA seq 1459 aa AA seqDB search MENQVFSVQQIQPNVISVRLFKRKVGGLGFLVKERVSKPPVIISDLIRGGAAEQSGLIQA GDIILAVNGQPLVDLSYDSALEVLRGIASETHVVLILRGPEGFTTHLETTFTGDGTPKTI RVTRPLAAPTTAVDLSHQSSASREHSPAVDRATGPGNGPQHTQDGGQEAGSLPHTKSRAP GPPGQDSAKKSIQGSQNSDLLKEIEPVLSLLTSGSKGINGGGPSKAETKDAEVQVDRGMD GKSHKPLPLGVENDRVFSDLWGKGHVPVVLNNPYSEKEQPPASGKQSPTKNGSPSKCPRF LKVKNWETDVVLTDTLHLKSTLEMGCTEHICMGSIMLPSQQIRRPEDVRTKEQLFPLAKE FIDQYYSSIKRFGSKAHTERLEEVNKEIETTGTYQLKDTELIYGAKHAWRNASRCVGRIQ WSKLQVFDARDCTTAHGMFNYICNHIKYATNKGNLRSAITIFPQRTDGKHDFRVWNSQLI RYAGYKQPDGSILGDPANVEFTEICVQQGWKPPRGRFDILPLLLQANGNDPELFQIPPEL VLEVPIRHPRFEWFKDLGLKWYGLPAVSNMLLEIGGLEFTACPFSGWYMGTEIGVRDYCD NSRYNILEEVAKNMNLDMRKTSSLWKDQALVEINIAVLYSFQSDKVTIVDHHSATESFIK HMENEYRCRGGCPADWVWIVPPMSGSVTPVFHQEMLNYRLTPSFEYQPEPWNTHVWKGTN GTPTKRRAIGFKKLAEAVKFSAKLMGQAMAKRVKATILYATETGKSQAYAKTLCEIFKHA FDAKVMSMEEYDIVHLEHETLVLVVTSTFGNGDPPENGEKFGCALMEMRHPNSVQEERKY PEPLRFFPRKGPPLPQGDTEVHGLAAARDSQQRSYKVRFNSVSSYSDSHKSSGDGPDLRD NFESAGPLANVRFSVFGLGSRAYPHFCAFGHAVDTLLEELGGERILKMREGDELCGQEEA FRTWAKKVFKAACDVFCVGDDVNIEKANNSLISNDRSWKRNKFRLTYVAEAPELTQGLSN VHKKRVSAARLLSRQNLQSPKSSRSTIFVRLHTNGNQELQYQPGDHLGVFPGNREDLVNA LMERLEDAPPVNQLVKVELLVERNTALGVISNWTDEHRLPPCTIFQAFKYYLDITTPPTP LQLQQFASLATSEKEKQRLLVLSKGLQEYEEWKWGKNPTIVEVLEEFPSIQMPTTLLLTQ LSLLQPRYYSISSSPDMYPDEVHLTVAVVSYHTRDGEGPIHHGVCSSWLNRIPADEVVPC FVRGAPSFHLPRNPQVPCILIGPGTGIAPFRSFWQQRQFDIQHKGMSPCPMVLVFGCRQS KIDHIYREETLQAKNKGVFRELYTAYSREPDKPKKYVQDILQEHLAEPVYRALKEQGGHI YVCGDVTMAADVLKAIQRIMTQQGKLSAEDAGVFISRLRDDNRYHEDIFGVTLRTYEVTN RLRSESIAFIEESKKDTDE NT seq 4380 nt NT seq  +upstreamnt  +downstreamnt atggagaatcaggtgttcagcgttcagcagatccaacccaacgtcatctccgtccgcctc ttcaagcgcaaggtggggggtctggggttcctggtgaaggagcgggtgagcaagccgccc gtgatcatctccgacctgattcgggggggtgccgcggagcagagcggcctcatccaggcc ggtgacatcatccttgcagtcaacggccagcccctggtggacctgagctatgacagcgcc ctggaggtgctcaggggcatcgcctctgagacccacgtggtcctcattctgaggggcccc gagggcttcaccactcacctggagaccaccttcaccggggacgggacccccaagaccatc cgcgtgacacggcctctggctgcccccaccaccgctgtcgatctgtctcaccagtcatca gccagcagagagcactcaccggcagtggacagggccacgggtcctggcaatgggccgcag cacacccaagacggtgggcaggaagccggctctctcccccataccaagagccgggctccc gggcccccaggccaggactctgccaagaagagcatccagggcagccaaaacagtgatttg ctcaaagagatagaacctgtactgagccttctcaccagtgggagcaaagggatcaatggc gggggaccttccaaggcagagacgaaggatgcagaagtccaggtggacagaggtatggat ggcaagtcacacaagccactgcccctgggcgtggagaatgaccgagtcttcagtgacctg tgggggaagggccacgtgcctgtcgtcctcaacaacccgtattcagagaaggagcagccc cctgcctcgggaaaacagtctcctacaaagaacggcagcccctccaagtgcccccgcttc ctcaaggtcaagaactgggagactgacgtggtcctcactgacacccttcaccttaagagc acactggaaatgggctgcaccgagcacatctgtatgggctccatcatgctcccctctcag cagatacgacggcctgaagacgtccgcacaaaagaacagctcttccctctcgccaaagag ttcattgaccagtactactcatcaattaaaaggtttggctccaaagcccacacggagagg ctggaagaggtgaacaaagagatcgaaaccaccggcacctaccagctcaaagacacggag ctcatctacggggccaagcatgcgtggcggaacgcctcccgctgcgtgggcaggatccag tggtccaagctgcaggtgttcgatgcccgcgactgcaccacggctcacgggatgttcaac tacatctgcaaccacatcaagtatgctaccaacaaagggaacctcagatccgccatcacc atattcccccagaggacggacggcaagcacgatttccgagtctggaactctcagctcatc cgctatgccggctacaagcagcctgatggctccatcctgggggacccagccaatgtggaa ttcacagagatctgtgtgcagcagggctggaaacccccaagaggccgcttcgatatcctg ccactcctgctccaggccaacggcaacgatcctgagctcttccagatccccccagagctg gtgttggaagtgcccatcaggcaccccaggtttgagtggttcaaggatctgggcctgaag tggtatggcctccccgctgtgtccaacatgctgctggagattggcggcctggagttcacc gcctgtcccttcagcggctggtacatgggcacagagattggcgtccgcgactattgtgac aactctcgatacaacatcctggaggaagtggccaagaacatgaacttggacatgaggaag acgtcctccctgtggaaggaccaagcactggtggaaatcaacattgctgttctctacagc ttccagagtgacaaagtgaccatcgttgaccaccactctgccaccgagtccttcatcaag cacatggagaatgaataccgctgccgggggggctgccccgccgactgggtgtggattgtg ccccccatgtctggcagtgtcacccctgtcttccaccaggagatgctcaactaccgactc accccgtccttcgaataccagcctgagccttggaacacccacgtctggaagggcaccaat ggaacccccacaaagcggcgagccatcggcttcaagaagctggcagaagccgtcaagttc tcagccaagcttatggggcaggcaatggccaagagggtcaaggcgaccatcctttatgcc acagagacgggcaagtcgcaggcttatgctaaaaccttgtgtgagatcttcaaacatgcc tttgatgccaaggtgatgtccatggaagaatatgacattgtacacctggaacatgaaact ctggtcctagtggttaccagcacttttggcaatggcgaccccccagagaatggggagaaa ttcggctgtgctttgatggaaatgaggcacccaaactccgtgcaggaggaaaggaagtac ccggaacccttgcgtttctttccccgtaaagggcctcccctcccccaaggtgacacagaa gtccatggtctggctgcagcccgtgacagccagcagaggagctacaaggtccgattcaat agtgtttcctcgtattctgactcccataaatcatcaggcgacgggccagacctcagagac aactttgagagtgctggacccctggccaacgtgaggttctctgtatttggccttggctcc cgggcttaccctcatttctgcgcctttggacatgccgtggacaccctcctggaggagctg ggaggagagaggatcctgaagatgagggagggagacgagctctgtgggcaggaagaggct ttcaggacgtgggccaagaaggtcttcaaggcagcctgcgatgtgttctgcgtgggagat gacgtcaacattgagaaggcaaacaactccctcatcagcaacgaccgcagctggaaaaga aacaagttccgcctcacctacgtggccgaagctccggaacttacacaaggtctatccaat gtccacaaaaagcgggtctcggccgctcgactcctcagccgccaaaaccttcagagccct aaatccagccgatcaacgatcttcgtgcgtctccacaccaatgggaatcaggagctgcag taccagcctggggaccacctgggcgtcttccctggcaaccgcgaggacctcgtgaacgcc ctgatggagcggctggaagatgctcccccagtcaaccagctggtgaaggtggaactgctg gtggagcggaacacggctttgggcgtcatcagtaactggacagatgagcaccgcctcccg ccctgcaccatcttccaggccttcaagtactacctggacatcaccacgccgcccacgccg ctgcagctgcagcagtttgcgtccctggccaccagcgagaaagagaagcagcgactgctg gtcctcagcaagggcttgcaggagtacgaggaatggaaatggggcaagaaccccaccatc gtggaggtgctggaagagttcccgtccatccagatgcccaccaccctgctcctgacccag ctgtccctgctgcagcctcgatactattcaatcagttcttccccagacatgtaccctgac gaggtgcacctcaccgtggccgttgtctcctaccacacccgagatggagaaggaccaatt caccacggcgtgtgctcctcctggctcaaccggataccggctgacgaagtggtcccctgt ttcgtgagaggagcacccagcttccacctgccccgaaatccccaagtgccctgtatcctc attggcccgggcactggcattgcccctttccgaagcttctggcagcagcgacaatttgat atccagcacaaaggaatgagcccctgccccatggtcctggtgtttgggtgccggcaatcc aagatagaccacatctacagggaggaaactctacaggccaagaacaagggggtcttcaga gaactctacacggcctactcgcgggagccagacaaaccaaagaagtacgttcaggacatc ctgcaggagcacttggcagaacctgtgtaccgagccctgaaggagcaagggggccacatt tacgtctgcggggacgtcaccatggccgccgatgtcctcaaagccatccagcgcatcatg acccagcaagggaaactctcagcggaggatgccggcgtgttcatcagcaggctgagggat gacaaccggtaccatgaggatattttcggggtcaccctgcgaacatatgaagtgaccaac cgccttagatctgaatccattgccttcattgaggagagcaaaaaagacactgatgagtaa

DBGET integrated database retrieval system