Puma concolor (puma): 112871472
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Entry
112871472 CDS
T08890
Symbol
PDE4B
Name
(RefSeq) cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X1
KO
K13293
cAMP-specific phosphodiesterase 4 [EC:
3.1.4.53
]
Organism
pcoo
Puma concolor (puma)
Pathway
pcoo00230
Purine metabolism
pcoo01100
Metabolic pathways
pcoo04024
cAMP signaling pathway
pcoo04928
Parathyroid hormone synthesis, secretion and action
pcoo05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
pcoo00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
112871472 (PDE4B)
09130 Environmental Information Processing
09132 Signal transduction
04024 cAMP signaling pathway
112871472 (PDE4B)
09150 Organismal Systems
09152 Endocrine system
04928 Parathyroid hormone synthesis, secretion and action
112871472 (PDE4B)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
112871472 (PDE4B)
Enzymes [BR:
pcoo01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.53 3',5'-cyclic-AMP phosphodiesterase
112871472 (PDE4B)
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Ortholog
Paralog
GFIT
Motif
Pfam:
PDEase_I
PDE4_UCR
Motif
Other DBs
NCBI-GeneID:
112871472
NCBI-ProteinID:
XP_025790300
UniProt:
A0A6P6IQ18
LinkDB
All DBs
Position
Unknown
AA seq
737 aa
AA seq
DB search
MKKSRSVMAVTADDNVKDYLECSLSKSYSSSSNTLGIDLWRGRRCCSGNLQLPPLSQRQS
ERARTPEGDGISRPTTLPLTTLPSIAITTVSQEGFDVENGPSPGRSPLDPQASSSSGLVL
HATFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQHGDDLIVTPFAQVLASLRSVR
NNFTVLTNLHGASNKRSPAAASQPPVSRVNLQEESYQKLAMETLEELDWCLDQLETIQTY
RSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKK
KKQQLMTQISGVKKLMHSSSLNNTSISRFGVNTENEDHLAKELEDLNKWGLNIFNVAGYS
HNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHYHSDVAYHNSLHAADVAQSTH
VLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHH
LAVGFKLLQEEHCDIFQNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVT
SSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGME
ISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWYQSMIPQS
PSPPLDEQNRDCQGLMEKFQFELTLEEEDSEGPEKDGEGHDYFSSPKTLCVIDPEHRDSL
GGTDVDIVTEDKSPIDT
NT seq
2214 nt
NT seq
+upstream
nt +downstream
nt
atgaagaaaagcaggagtgtgatggcagtgacggctgatgataatgtgaaagattatctt
gaatgtagcttgagtaaatcctacagttcttctagtaacacacttgggatcgacctctgg
agagggagaaggtgttgctcaggaaacttacagttaccgcccctgtcccaaagacagagt
gagagggcaaggactcccgagggagatggcatttccagacctaccacgctacctttgacg
acactcccaagcatcgctattacaaccgtaagccaggagggctttgatgtggaaaatggc
ccttccccaggtcggagcccactggacccccaggccagctcttcctctgggttggtgctc
catgccacctttcctgggcacagccagcggagagagtcctttctctaccgatcagatagc
gactatgatttgtcaccgaaggcgatgtcaagaaactcttcacttccaagcgagcaacac
ggcgatgacttgattgtaacaccttttgcccaggtccttgccagcttgcgaagtgtgaga
aacaattttactgtactgacaaaccttcatggagcatccaacaagaggtccccagctgct
gctagtcagccacctgtctccagagtaaacctgcaagaagaatcttatcaaaaattagca
atggaaacgctggaggaattggactggtgcttagaccagctagagaccatccagacctac
cgctctgtcagtgagatggcttctaacaagttcaagagaatgctgaaccgggagctgaca
cacctctcagagatgagccgatcagggaaccaggtttctgaatacatttcaaatactttc
ttagacaagcagaatgatgtggagattccatcacccacccagaaggacagagagaaaaag
aaaaagcaacagctcatgacgcagataagcggagtgaaaaaactgatgcacagttcaagc
ttaaacaatacaagcatctcacgctttggagtcaacacagaaaatgaagatcatctggcc
aaggagctggaagatctgaacaaatggggccttaacatcttcaatgtggctggatattca
cacaataggcccctcacatgcatcatgtatgccatattccaggaaagagacctcctaaag
acattcaaaatctcatctgatacatttgtaacctacatgatgactttagaagaccattac
cattctgatgtggcgtatcataacagcctacatgctgctgatgtagcccagtcaacccat
gttcttctttctacgccagcattagatgctgtcttcacagatttggaaattctggccgcc
attttcgcagctgctatccatgatgttgatcaccctggagtctccaaccagtttctcatc
aacacaaattcagaacttgctttgatgtataatgatgaatctgtgttggaaaaccatcac
cttgccgtgggtttcaaactgctgcaagaagaacactgtgatatcttccagaatctcacc
aagaagcaacgccagacactcaggaaaatggttatcgacatggtgttagcaactgatatg
tccaaacatatgagcctgctggcagacctgaaaacaatggtggaaacaaagaaagttaca
agttcaggtgttcttctcctggacaactacacggatcgtatacaggtccttcgcaacatg
gtacactgtgcagacctaagcaaccccaccaagtccttggaattatatcggcagtggaca
gaccgcatcatggaggagttcttccagcagggagacaaagagcgggagaggggaatggag
attagcccaatgtgtgataagcacacagcttctgtggaaaaatcccaggttggtttcatt
gactacattgtccatccactctgggagacctgggcagatctggtgcagcctgatgcccag
gacattctggacacgttagaagataatagaaactggtatcagagcatgataccacagagt
ccctccccaccactggacgagcagaacagagactgtcagggtctgatggagaagtttcaa
tttgaactgacccttgaagaggaggattccgaaggcccagaaaaagacggagagggtcac
gactatttcagcagcccaaagacactttgtgtgattgatcctgaacatagggattcacta
ggagggactgatgtagacattgtgacagaagacaagtcccctatcgacacataa
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