Puma concolor (puma): 112871843 Help Entry 112871843         CDS       T08890                                  Symbol TSC1 Name (RefSeq) hamartin   KO K07206   tuberous sclerosis 1 Organism pcoo  Puma concolor (puma) Pathway pcoo04072   Phospholipase D signaling pathway pcoo04140   Autophagy - animal pcoo04150   mTOR signaling pathway pcoo04151   PI3K-Akt signaling pathway pcoo04152   AMPK signaling pathway pcoo04211   Longevity regulating pathway pcoo04218   Cellular senescence pcoo04714   Thermogenesis pcoo04910   Insulin signaling pathway pcoo05163   Human cytomegalovirus infection pcoo05165   Human papillomavirus infection pcoo05168   Herpes simplex virus 1 infection pcoo05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:pcoo00001]  09130 Environmental Information Processing   09132 Signal transduction    04072 Phospholipase D signaling pathway     112871843 (TSC1)    04151 PI3K-Akt signaling pathway     112871843 (TSC1)    04152 AMPK signaling pathway     112871843 (TSC1)    04150 mTOR signaling pathway     112871843 (TSC1)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     112871843 (TSC1)   09143 Cell growth and death    04218 Cellular senescence     112871843 (TSC1)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     112871843 (TSC1)   09149 Aging    04211 Longevity regulating pathway     112871843 (TSC1)   09159 Environmental adaptation    04714 Thermogenesis     112871843 (TSC1)  09160 Human Diseases   09161 Cancer: overview    05231 Choline metabolism in cancer     112871843 (TSC1)   09172 Infectious disease: viral    05168 Herpes simplex virus 1 infection     112871843 (TSC1)    05163 Human cytomegalovirus infection     112871843 (TSC1)    05165 Human papillomavirus infection     112871843 (TSC1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Hamartin Motif Other DBs NCBI-GeneID:  112871843 NCBI-ProteinID:  XP_025790704 UniProt:  A0A6P6ISB7 LinkDB All DBs Position Unknown AA seq 1161 aa AA seqDB search MAQQANIGELVSMLDSPVLSVRDDVTAVFKENLNSDRGPMLVNTLVDYYLETSSQPVLHI LTTLQEPHDKHLLDKMNDCVGRAASRLPALSLLGHVIRLQPPWKHKLSQAPLLPSLLKCL KVDTDVIVLTTGVLVLITMLPMIPQSGKQHLHDFFDIFGRLSSWCLKKPGHVTEIYLVHL HASVYALFHRLYGMYPCNFVSFLRSHYSMKENLDTFEEVVRPMMEHVRIHPELVTGSKDH ELDPRRWKRLETHDVVIECAKISLDPTEASYEDSDSVSPQVSAHFPHRAADVAASPYVDT QNSCGSATSTPYSGSRLTLLNTPGQPPQTLSPPSTRLSTEPPQATLWSPSMVCGMTTPPT SPGNVPPDLSHPYSKAFGPTGGKGTPLGTPATSPPPAPLCHPDDYVHPSVLQATATPPRK EERTDSARPCLHRQHHLPNDRGLEELSGSKGSVTLSDLPGFLGDLASEEDSVEKDKEEAA ISKELSEITTADAELLVPRGGFDSPFYRDSLPGCPRKTHSAASVAHGTSVNPEPLNSSLD KLGPDAPKQAFTPIDLPCGGTSESPAGNRERQASLETNILTPSPCKIPPQRGVGLGSGQP PPYEHLFEVALPKTAHHFVGKKTKELLKKAKGNAEEDRAPSTSPVEILDRLIQQGADAHS KELNRLSLPSKSVDWTHFGGSPPSDEIRTLRNQLLLLHNQLLYERFKRQQHALRNRRLLR RVTRAAALEEHNAAMKDQLKLQEKDIQIWKVSLQKEQARNSQLQEQRDTMVTQLHSQIRQ LQHDREEFYNQSQELQTKLEDCRNMIAELRLELKKANSKVCHTELLLSQVSQKLSNSESV QQQMEFLNRQLLVLGEVNELYLEQLQNKHSDTTKEVEMMKAAYRKELEKNRSHVLQQNQR LDTSQKRILELESHLAKKDHLLLEQKKYLEDVKLQARGQLQAAESRYEAQKRITQVFELE ILDLYGRLEKDSLLKKLEEEKAEAAEAAEERLACCKDGCSDSVTGHNEEAPGHNGETKPP RPAGVRGGGGSRGGSSGELSTPEKPPSQRAGPFGSRWETTTGEPATSIPTTVGSLPSSKS FLGRKARELFRNKSESQCDEDSVTISSLSETLKTEPGKDPGAEGKAPPSLDGPHPSPPTP DSVGQLHIMDYNETHHEHSEG NT seq 3486 nt NT seq  +upstreamnt  +downstreamnt atggcccagcaagccaacatcggggagctcgtctccatgctggactcccccgtgctgagc gtgcgtgatgacgtaacagccgtctttaaagagaacctcaattctgaccgtggtccgatg ctcgtaaacaccttggtggattattacctggaaaccagttctcagccggtattgcacatc ctgactaccctgcaagagccgcacgataagcacctcctggacaaaatgaacgactgtgtg ggcagagccgcctcgcggttgcccgccctgtcgttgctgggccacgtcatcaggctgcag ccgccctggaagcacaagctgtctcaagcacctctcttgccttctttgctcaaatgtctc aaggtggacaccgatgtcattgtcctcacaacaggtgtcttagtgttgataaccatgcta ccaatgattccacagtcggggaaacagcaccttcatgatttctttgatatttttggccgt ctttcgtcgtggtgcctgaagaaaccaggccacgtgacggaaatctatcttgtccatctc cacgccagcgtctacgctctttttcatcgcctctatggaatgtacccttgcaactttgtc tcctttctacgctctcactacagtatgaaggagaacttggacacttttgaagaggtggtc aggccgatgatggagcatgtgcgaattcacccggaattagtgactggatccaaggaccac gaactggaccctcgaaggtggaagagattagaaacgcacgatgttgtgatagagtgtgcc aaaatctctctggaccccacagaagcctcgtatgaagacagcgactctgtgtccccccag gtgtcagcacactttcctcatcgtgcggccgatgtggccgccagcccttacgtcgacacg cagaatagctgtgggagtgctacctcgaccccttattccggctctcggctgacattgtta aatacgcccgggcagccacctcagactctgagtcccccatcaacacggctgtcgactgag ccgccacaagctactctctggagcccgtctatggtttgtggtatgaccactcctccaact tctcctggaaacgtcccacctgacctgtcacacccttacagtaaagcctttggtccaact ggtggaaaagggactcctctgggaaccccagcaacgtctcctcctccagccccactctgc cacccggacgactacgttcacccatccgtcctgcaggccacggccacgccccccaggaag gaagagagaacagattcagcaaggccctgtctacacagacaacaccatcttccgaatgac agaggattagaagagctatctggcagcaaaggttctgtcactctcagtgaccttccaggg tttttaggggacctggcctcggaagaagatagtgttgaaaaagataaagaagaagcggca atatctaaagagctctccgagatcaccacagctgacgccgagctcctggttcctcgagga ggcttcgactctcccttctaccgggacagtctcccgggctgccctcggaagacccattcg gccgcctccgtcgctcacggcaccagtgtgaaccctgagcctttaaactcctccctggac aagcttgggcctgacgcaccaaagcaagcctttactcccatagatctgccctgtggaggc accagcgagagccctgccgggaacagggagcgccaggcttcgctggagaccaacatcctc actcccagcccttgtaaaatcccgcctcagaggggcgtgggccttggaagtgggcagcct cccccttacgagcatctttttgaggtggcgttgccaaagaccgcccatcacttcgtcggc aagaagaccaaggaactgttaaagaaagcgaaagggaacgcggaggaagaccgtgcgccc tctacctccccggtggaaatactggatagactgatacagcagggagcggacgcacacagc aaggagctgaacaggttgtctttacccagcaagtctgtcgactggacccactttggaggc tctcctccctcagatgagatccgcaccctccgtaaccagttgcttttactgcacaaccag ctgctctatgagcgttttaagaggcagcagcatgctctccggaacaggcgactcctccgt cgggtgaccagggcggcggctctggaggagcacaacgccgccatgaaagaccagctgaag ttacaagagaaggacatccagatatggaaggtcagtctgcagaaggaacaagccagaaac agtcagctgcaggagcagcgagacacgatggtgacccagctccacagccagatcagacag ctgcagcacgaccgagaggagttctacaaccagagccaggagctgcagacaaagctggag gactgcaggaacatgatcgcagagctgcgtctggagttgaagaaagccaacagtaaggtg tgccataccgagctgctgctcagtcaggtctcccagaagctctcgaacagcgagtcggtc cagcagcagatggagttcttgaacaggcagctgctcgtccttggggaggtcaacgagctg tatctggagcagctgcagaacaagcactcggacaccacaaaggaagtggaaatgatgaaa gctgcatatcggaaagaactagaaaaaaacagaagccatgtcctccagcagaatcagagg ctcgacacctctcagaaacggattttggaactggaatctcacctggccaagaaagaccac cttcttttggaacagaagaaatatttagaggatgtcaaactccaggccagaggacagctg caggcggcagagagcaggtatgaggctcagaagaggatcacccaggtgtttgagttggag atcttagatttatacggcaggttggagaaggacagcctcctgaagaaacttgaagaagaa aaagcagaagcagcagaagcggcagaagaaaggcttgcctgttgtaaggacggctgctcg gattctgtaacagggcacaacgaagaggcacctggccacaacggcgagaccaagcccccc aggcccgccggtgtgcggggcggcggtggaagcagagggggcagcagtggcgagctctcg accccggagaagccccccagccagagggcgggcccgttcggcagtcggtgggagacgacc acgggagagcccgccaccagcatcccgaccaccgttggctcccttcccagttcgaaaagc ttcctgggcaggaaggcgcgagagttatttcgtaataagagcgagagccagtgtgacgag gacagcgtgaccatcagtagcctttctgaaacgctaaagacagaaccgggcaaagacccg ggtgcggaaggcaaggcccccccgagcctagacggcccgcacccgtcccccccgaccccg gacagtgttggacagctgcatatcatggactacaacgagactcatcatgaacacagcgaa ggatga

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