KEGG   Propithecus coquereli (Coquerel's sifaka): 105805988
Entry
105805988         CDS       T08746                                 
Symbol
RAC1
Name
(RefSeq) ras-related C3 botulinum toxin substrate 1 isoform X1
  KO
K04392  Ras-related C3 botulinum toxin substrate 1
Organism
pcoq  Propithecus coquereli (Coquerel's sifaka)
Pathway
pcoq04010  MAPK signaling pathway
pcoq04014  Ras signaling pathway
pcoq04015  Rap1 signaling pathway
pcoq04024  cAMP signaling pathway
pcoq04062  Chemokine signaling pathway
pcoq04071  Sphingolipid signaling pathway
pcoq04145  Phagosome
pcoq04148  Efferocytosis
pcoq04151  PI3K-Akt signaling pathway
pcoq04310  Wnt signaling pathway
pcoq04360  Axon guidance
pcoq04370  VEGF signaling pathway
pcoq04380  Osteoclast differentiation
pcoq04510  Focal adhesion
pcoq04520  Adherens junction
pcoq04530  Tight junction
pcoq04613  Neutrophil extracellular trap formation
pcoq04620  Toll-like receptor signaling pathway
pcoq04650  Natural killer cell mediated cytotoxicity
pcoq04662  B cell receptor signaling pathway
pcoq04664  Fc epsilon RI signaling pathway
pcoq04666  Fc gamma R-mediated phagocytosis
pcoq04670  Leukocyte transendothelial migration
pcoq04722  Neurotrophin signaling pathway
pcoq04810  Regulation of actin cytoskeleton
pcoq04932  Non-alcoholic fatty liver disease
pcoq04933  AGE-RAGE signaling pathway in diabetic complications
pcoq04972  Pancreatic secretion
pcoq05014  Amyotrophic lateral sclerosis
pcoq05020  Prion disease
pcoq05022  Pathways of neurodegeneration - multiple diseases
pcoq05100  Bacterial invasion of epithelial cells
pcoq05132  Salmonella infection
pcoq05135  Yersinia infection
pcoq05163  Human cytomegalovirus infection
pcoq05167  Kaposi sarcoma-associated herpesvirus infection
pcoq05169  Epstein-Barr virus infection
pcoq05170  Human immunodeficiency virus 1 infection
pcoq05200  Pathways in cancer
pcoq05203  Viral carcinogenesis
pcoq05205  Proteoglycans in cancer
pcoq05208  Chemical carcinogenesis - reactive oxygen species
pcoq05210  Colorectal cancer
pcoq05211  Renal cell carcinoma
pcoq05212  Pancreatic cancer
pcoq05231  Choline metabolism in cancer
pcoq05415  Diabetic cardiomyopathy
pcoq05416  Viral myocarditis
pcoq05417  Lipid and atherosclerosis
pcoq05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pcoq00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    105805988 (RAC1)
   04014 Ras signaling pathway
    105805988 (RAC1)
   04015 Rap1 signaling pathway
    105805988 (RAC1)
   04310 Wnt signaling pathway
    105805988 (RAC1)
   04370 VEGF signaling pathway
    105805988 (RAC1)
   04071 Sphingolipid signaling pathway
    105805988 (RAC1)
   04024 cAMP signaling pathway
    105805988 (RAC1)
   04151 PI3K-Akt signaling pathway
    105805988 (RAC1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    105805988 (RAC1)
   04148 Efferocytosis
    105805988 (RAC1)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    105805988 (RAC1)
   04520 Adherens junction
    105805988 (RAC1)
   04530 Tight junction
    105805988 (RAC1)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    105805988 (RAC1)
 09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    105805988 (RAC1)
   04620 Toll-like receptor signaling pathway
    105805988 (RAC1)
   04650 Natural killer cell mediated cytotoxicity
    105805988 (RAC1)
   04662 B cell receptor signaling pathway
    105805988 (RAC1)
   04664 Fc epsilon RI signaling pathway
    105805988 (RAC1)
   04666 Fc gamma R-mediated phagocytosis
    105805988 (RAC1)
   04670 Leukocyte transendothelial migration
    105805988 (RAC1)
   04062 Chemokine signaling pathway
    105805988 (RAC1)
  09154 Digestive system
   04972 Pancreatic secretion
    105805988 (RAC1)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    105805988 (RAC1)
  09158 Development and regeneration
   04360 Axon guidance
    105805988 (RAC1)
   04380 Osteoclast differentiation
    105805988 (RAC1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    105805988 (RAC1)
   05205 Proteoglycans in cancer
    105805988 (RAC1)
   05208 Chemical carcinogenesis - reactive oxygen species
    105805988 (RAC1)
   05203 Viral carcinogenesis
    105805988 (RAC1)
   05231 Choline metabolism in cancer
    105805988 (RAC1)
  09162 Cancer: specific types
   05210 Colorectal cancer
    105805988 (RAC1)
   05212 Pancreatic cancer
    105805988 (RAC1)
   05211 Renal cell carcinoma
    105805988 (RAC1)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    105805988 (RAC1)
   05163 Human cytomegalovirus infection
    105805988 (RAC1)
   05167 Kaposi sarcoma-associated herpesvirus infection
    105805988 (RAC1)
   05169 Epstein-Barr virus infection
    105805988 (RAC1)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    105805988 (RAC1)
   05135 Yersinia infection
    105805988 (RAC1)
   05100 Bacterial invasion of epithelial cells
    105805988 (RAC1)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    105805988 (RAC1)
   05020 Prion disease
    105805988 (RAC1)
   05022 Pathways of neurodegeneration - multiple diseases
    105805988 (RAC1)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    105805988 (RAC1)
   05418 Fluid shear stress and atherosclerosis
    105805988 (RAC1)
   05415 Diabetic cardiomyopathy
    105805988 (RAC1)
   05416 Viral myocarditis
    105805988 (RAC1)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    105805988 (RAC1)
   04933 AGE-RAGE signaling pathway in diabetic complications
    105805988 (RAC1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:pcoq04131]
    105805988 (RAC1)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:pcoq04147]
    105805988 (RAC1)
   04031 GTP-binding proteins [BR:pcoq04031]
    105805988 (RAC1)
Membrane trafficking [BR:pcoq04131]
 Exocytosis
  Small GTPases and associated proteins
   Rho GTPases
    105805988 (RAC1)
 Endocytosis
  Lipid raft mediated endocytosis
   Arf6-dependent endocytosis
    105805988 (RAC1)
  Macropinocytosis
   Ras GTPases
    105805988 (RAC1)
 Others
  NADPH oxidases (Nox) and associated proteins
   Nox associated proteins
    105805988 (RAC1)
Exosome [BR:pcoq04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   105805988 (RAC1)
  Exosomal proteins of other body fluids (saliva and urine)
   105805988 (RAC1)
  Exosomal proteins of colorectal cancer cells
   105805988 (RAC1)
  Exosomal proteins of bladder cancer cells
   105805988 (RAC1)
GTP-binding proteins [BR:pcoq04031]
 Small (monomeric) G-proteins
  Rho Family
   Rac/Cdc42 [OT]
    105805988 (RAC1)
SSDB
Motif
Pfam: Ras Roc Arf GTP_EFTU CagD
Other DBs
NCBI-GeneID: 105805988
NCBI-ProteinID: XP_012494439
Ensembl: ENSPCOG00000020411
UniProt: A0A2K6FTB6
LinkDB
Position
Unknown
AA seq 192 aa
MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAG
QEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLR
DDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPP
PVKKRKRKCLLL
NT seq 579 nt   +upstreamnt  +downstreamnt
atgcaggccatcaagtgtgtggtggtcggagacggagctgtaggtaaaacttgcctactg
atcagttatacaaccaatgcatttcctggagaatatatccctactgtctttgacaattat
tctgccaatgttatggtagatggaaaaccggtgaatctgggcttatgggatacggctgga
caagaagattatgacagattacgccccctgtcctatccacaaacagatgtattcttaatt
tgcttttcccttgtgagtcctgcatcatttgaaaatgtccgagcaaagtggtatcctgaa
gtgcgacaccattgtcccaacactcccatcatccttgtgggaaccaaacttgatcttagg
gatgataaagacacgattgagaaactaaaggagaagaagctgactcccatcacctatccg
cagggtttagccatggctaaagagatcggtgctgtaaaatacctggagtgctcggctctc
acacagcgaggcctcaagacagtgtttgacgaagctatccgagcagttctctgcccacca
cctgtcaagaagaggaagagaaaatgcctgctgttgtaa

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