Propithecus coquereli (Coquerel's sifaka): 105806641
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Entry
105806641 CDS
T08746
Symbol
SETX
Name
(RefSeq) probable helicase senataxin
KO
K10706
ATP-dependent RNA/DNA helicase, senataxin [EC:
5.6.2.5
5.6.2.3
]
Organism
pcoq
Propithecus coquereli (Coquerel's sifaka)
Pathway
pcoq05014
Amyotrophic lateral sclerosis
Brite
KEGG Orthology (KO) [BR:
pcoq00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
105806641 (SETX)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03021 Transcription machinery [BR:
pcoq03021
]
105806641 (SETX)
Enzymes [BR:
pcoq01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.3 DNA 5'-3' helicase
105806641 (SETX)
5.6.2.5 RNA 5'-3' helicase
105806641 (SETX)
Transcription machinery [BR:
pcoq03021
]
Eukaryotic type
RNA polymerase II system
Other transcription-related factors
Transcription termination factor
105806641 (SETX)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
AAA_11
AAA_12
AAA_19
AAA_30
UvrD-helicase
nSTAND3
AAA_22
SLFN-g3_helicase
ResIII
NAT10_TcmA_helicase
AAA_16
UvrD_C_2
Motif
Other DBs
NCBI-GeneID:
105806641
NCBI-ProteinID:
XP_012495286
Ensembl:
ENSPCOG00000022383
UniProt:
A0A2K6G3I4
LinkDB
All DBs
Position
Unknown
AA seq
2676 aa
AA seq
DB search
MTTCCWCTPGGVSTIDFLKCYVSKTQSSEFQTADEDLCYCLECVTEYHKARDEVPFLHEV
LWELETSRLINHFEKSMKAEIGEDDELYIVDNNGEAQLFDFTGQDFENKLRVPLLEILKY
PYLLLHERVNELCVEALCRMEQANCSFQVFDKHPGIYLFLVHPNEMVRRWAILTARNLGK
VDRDDYYDLQDVLTCLFKVIELGLLESPDIYTSSVLEKGKLILLPSHMYDTTNYKNYWLG
ICMLLTILEEQAMDSLLLGSDKQNDFMQSILHTMERQSDDESVDPFWPALHCFMVILDRL
GSKVWGQLIDPIEALQTIINNVSYNREIQHIRNSSVRTKLEPESYLDDMVTCSQIVYNYN
PEKTKKDSGWRSAICPDYCPNMYEEMETLASVLQSDIGQDMRVHNSTFLWFIPFVQSLMD
LKDLGVAYIAEVIHHLHSEVKDVLNQTDAVCDKVTEFFLLILVSVIELHRNKKCLHLLWI
SSQQWVEVVVKCAKLPTTAFARSSEKSSGNCSKGTAMISSLSLHSMPSNSVQLACVQLIR
SLLKEGYQLGQQTICKRFWDKLNLFLRGNLSLGWQLTSQETHELQTCLKQIIRNVKSKVP
PCSTLVDLTLTCKTPPASYNKEESEQIGKKSVKDIHCLENSSPTFSKELMKADIYQLPES
ISIKASNTVEEEDNEQNYMKDLKLEDHRSAESCLKQGSKSLFIKKAQDQIKSTRKQKSVK
ENSSYTPQNCTSRNGPGRGSDREITSTHFLTDSSTESLEKVSASNADFSFKDDALGKTSK
PKTKTQKKDEICAKLSHVIKKQHGKRTLVRNAVDLEENLTASNTESFYSGKDTEVQKGDG
FIHNLSSNPSGIPDDNKNGEQKSQNSLLLKKKQVKNEELDIFSSLENNCKVQEHHLDQDL
VSFTEMTDTLVKKTSPFKAPMTVVELREKEMSKSTLVSCNLTIGQAPGISPKSETLTDSQ
IDRDLHKLSLMAQASVTKFPSDSTQKSSSQLQRKVKDEKRYFTANQNNVGDTGGGQVIII
SDSDDEDEGILSDEKHMKQDKTCVEKECPEQHVSVVTSNVEKKPIKKEQTKSLPQFEDSD
SQFFEFESPSEVFSVWQDHKLDSSVQEDEKNSCSTHMTDTTNIWDDDDTDYASKEVIKKE
GIEGHTEAQSSISVEEFHETEGKKPKRKRFTKKTVAKDPLSPSCAARSEDQSHINEKEIP
ENDFKKSVDIKTTTSNSSIQKATTVSPRKSSPKLRTCPEPVRRVPLSKTPKKAHSDTRKG
QSKNSNYIRCRTSPAIVPPKKFRQCPEPTSTAEKLGLKKAPRKAFDLSQRSLESLVQLRD
HGKTVGVVDTRKKTKLIPPQTLSVKNNKKLLTSQDLQMQRQIRHKSQRNRQGLVDYGSTD
ATKAVPHTAQNSDTFVPESDKLDYNYTGGTKVLANGNGKQLKKCMSSEPETIKAKCVSQA
TDDACLLNQCDSVVLNGIPTNEIIVSTSEDPLAGGDPIVHPIEVATLKEGESESNSDIED
DNLFLTQNDPEDMDLCSQVENDNVKLIEVVHGKDTVQVEVSLSWPQLESLSGTKCKYKDC
VEVRKNQSEYCSKHSEAKAADEDVFRKPGLPLSASKPSRPSTAKIFSSRSTSRIANLSRS
LENATALPPALKNKPNGVQSILKVPQAAPIIFQKPVGEMKSLCNVLHPQTPDNSNRQGYK
LLFGENKSFSTSSPVNILLSSQSISDTFVKEVLKWKYEMFLNFDQCGPPASLCQSISRPV
PVRFQDCEDYFHVFFPLMILNTFETVAQEWLSSPNKENFYQLHLRKFPADYKKYWEFVVY
LEECELAKQLHPKENDLVFLVPERQNGEKKDIERNCMQDLHEYHCGYVHKFRRTSVMRNG
KSECSLSIQTQDNLPANLNELVKCIVISSLVTTQRKLKAMSLLNGRNQLARAVLNPNPMD
FCTKDLLTTTSERIIAYLKDFNEDQKKAIETAYAMVKQSPSVAKICLIHGPPGTGKSKTI
VGLLYRLLTENQRKGHSDENFNAKIKQNRVLVCAPSNAAVDELMKKIILGFKEKCKDKKN
PLGNCGDINLVRLGPEKSINNEVLKFSLDSQVNHRMKKDLPSHVQDMHRKKDSLDHQLDE
LSRQRALCRGGREIQRQELDEKIAKVSKERQELASKIKEVQGRPQKTQSIIILESHVICC
TLSTSGGLLLESAFRGQGGVPFSCVIVDEAGQSCEVETLTPLIHRCNKLVLVGDPKQLPP
TVISMKAQEYGYDQSMMARFYKLLEENVEQNMIGRLPILQLTVQYRMHPDICLFPSNYIY
NRTLKTNRQTETFRCSSDWPFQPYLVFDVGDGSERRDNDSYVNVQEIKLVMEIIKLIKDK
RRDVTFRNIGIITHYKAQKTMIQKDLDKEFDRKGPAEVDTVDAFQGRQKDCVIVTCVRAN
AMQGSIGFLASLQRLNVTITRAKYSLFILGHLRTLMENQHWNHLIQDAQKRGAIIKTCDK
NYRHDAMKILKLKPVLQRSLTHPPTIAPEVSRPQSGLPSNSLDSGFVSPLYHTPPDCGEA
AVTSKDPERLPVQDLLRDPRLLRRMGADANGKFLRDPQSSSPQHPGATPPVGEPSFPIPQ
QDLGSGVQQSTGTAPSSHKPHVQCEPPAASADASNSKRKCSDLEEGLSHRRETRTLSEEE
QEKHGSVPHHTNRNSEWDKKRLEREEDSSSKKRKLS
NT seq
8031 nt
NT seq
+upstream
nt +downstream
nt
atgaccacatgttgttggtgtacgccaggtggtgtttccaccattgacttcttaaagtgc
tatgtgtctaagacccaatccagtgaatttcaaacagctgatgaagacctctgctactgc
ttagagtgtgtgactgaataccacaaagcaagagatgaagtaccattcttgcatgaggtt
ttatgggaattagaaacctcacgtctcataaatcacttcgaaaaatccatgaaggcagaa
attggagaggatgatgaattatatatagtagacaacaatggagaggcacaactgtttgac
tttactggccaagactttgaaaataagcttcgagttcctcttcttgaaatactcaaatat
ccttacctgcttctacacgaacgtgttaatgaattatgtgttgaagcactttgtcggatg
gaacaagccaattgctcctttcaggtgttcgacaaacatccggggatctatttgttcttg
gtccatcccaatgaaatggttcgacgctgggctatcctgactgcaagaaacttgggaaaa
gtggacagagatgattattatgacttacaagatgttttaacttgcctttttaaagtcatc
gagttggggcttttagaaagtccagacatttatacgtcttctgtccttgagaagggtaaa
ctgattcttctgccctcacacatgtatgatactaccaactacaaaaactattggttaggt
atttgcatgttgctgaccattcttgaggagcaagccatggattctctgttgttgggctca
gacaaacaaaatgattttatgcagtcaatacttcacaccatggagaggcagtcagatgat
gagagtgtggatcctttctggccagcattacattgtttcatggtgattctggatcgcctg
ggatccaaggtctggggtcagcttattgaccccattgaggcattgcaaaccattatcaac
aatgtgagctacaatcgggagatccaacacatacggaacagttctgtgaggaccaagtta
gagccagaatcatatttggatgatatggtgacttgcagccagattgtatacaattataat
cctgaaaagaccaaaaaggattctggatggagatcagccatttgcccagattattgtcct
aacatgtatgaagaaatggaaacattagccagtgtacttcagtcagatattggtcaagac
atgcgtgttcataacagcacatttttgtggttcataccttttgttcagtccctcatggat
cttaaggatttaggtgtggcttacatagcagaggttattcatcatctgcactccgaagtc
aaagatgtcctcaaccaaacagatgctgtgtgtgacaaagtcactgaattttttcttcta
attttggtatcagtgattgaactgcacagaaataaaaaatgtttgcatttgctatggatt
agttcccaacaatgggtggaagtcgtcgtaaaatgtgccaagcttcctaccacagcattt
gcacggagttctgagaagtcatctggaaattgctccaaaggaacggcaatgatatcatca
ctgtcgttgcattcaatgccatctaactctgtacagcttgcatgtgtgcaactgattaga
agtctccttaaagaaggttatcagcttgggcagcaaactatttgtaagcgattttgggat
aagcttaacttattccttcggggaaatttatctctaggttggcagttgactagtcaggaa
acccatgagttacaaacatgtttaaagcaaattattagaaatgtaaaatcaaaagtacct
ccatgtagcactttagtggatctgactcttacatgtaaaacccctcctgcatcttataat
aaagaagaaagtgaacaaatagggaagaagtctgtaaaagacatacattgtctagaaaac
tccagcccaacattttctaaagaactgatgaaagctgacatatatcaactaccagaaagt
atatcaatcaaagcaagtaacactgtagaagaagaggataatgagcaaaattatatgaag
gatttgaaattagaagaccatcggtcagctgagtcatgcttaaagcagggtagtaaaagc
ctttttattaaaaaagctcaggatcaaattaaaagtacaaggaagcagaagtctgtaaaa
gagaactcctcatataccccacagaattgtacttcaagaaatggtccaggaaggggaagc
gacagagaaataacatcaacacattttttgactgattctagcactgaatctctggaaaaa
gtgtccgcatcaaatgcagatttctctttcaaggatgatgctcttggtaaaacctcaaaa
ccaaaaacgaagacacagaagaaagatgaaatctgtgcaaagttatcacacgtaataaag
aagcaacatgggaaaagaactttggtccgtaatgctgttgatttagaggaaaacctgact
gcatctaacactgagagtttctattcagggaaagatacagaagttcagaaaggggatggc
tttatacacaatctatcttcaaaccctagtggtattccagatgataataaaaatggagaa
caaaaatcccaaaatagcttattactgaaaaagaaacaagtaaagaatgaagagttagat
attttctcttcccttgaaaacaattgtaaagtacaggaacatcatcttgatcaagatttg
gtctcatttacagaaatgactgatactttagtgaagaaaacgtctccctttaaagctccg
atgactgtagttgaattgagagagaaggaaatgagtaagagtactctggtttcttgtaac
ttgacaataggacaggcccctggcatcagtcctaagtctgaaaccttaacggattctcag
atagacagagacctccacaagttatctttaatggctcaagccagtgttactaagtttcca
tcagattcaactcaaaaaagctcatctcagctccaaagaaaagtaaaagatgaaaaaagg
tatttcacagctaaccaaaataatgttggagacactggcggtggacaggttattattatt
tcagattctgatgatgaagatgaaggaattctgagtgatgagaaacacatgaaacaggac
aaaacatgcgtggagaaagaatgtccagagcagcacgtttcagtagttactagtaatgta
gaaaagaagccaataaagaaagaacaaacaaagtctcttccgcagttcgaggattctgat
tctcagttttttgagtttgaaagtccatctgaagtgttttcagtttggcaggatcataaa
ctagatagttcagttcaagaagatgaaaaaaattcatgttcgactcacatgactgatacc
acaaatatttgggatgatgatgatacagattatgcatctaaagaggttattaaaaaagaa
ggcattgaaggacacacagaagcacagagtagtatttctgttgaggaatttcatgaaact
gaagggaaaaaacctaagagaaaacgatttacaaaaaaaacagtggctaaagatcctctg
agcccttcatgtgctgccagaagtgaggaccagtctcatattaatgagaaagagattcct
gaaaatgattttaaaaaaagtgtagacataaagactacaacttccaattcaagtattcag
aaagccactacggtttccccaaggaagtcttctccaaagcttcgtacttgtccagaaccc
gttaggagagtcccactttctaaaacccctaagaaagcacattcagataccagaaaaggg
cagagtaaaaattcaaattacatacgttgtagaacatctcctgcgatagtgccaccaaag
aaatttcgccagtgtcctgaaccaacctcaacagctgagaaacttggtctgaaaaaggct
cctcgtaaggcatttgacttgtcccagcgatctttagagtctttagttcaattacgtgat
catggcaaaactgttggagtagtcgataccagaaaaaaaactaaattaattcctcctcag
actctttctgtcaaaaataataagaaactcctaaccagtcaagatctccagatgcaaagg
cagataagacacaaatcacaacgaaatagacaagggctcgttgattatggaagtacggat
gctacaaaagcagtgccacatacagcacagaattctgacacatttgtaccagaatctgat
aagttagattataattatacaggaggaactaaggtacttgccaacggtaatggaaaacag
ttaaaaaaatgcatgtcttctgaaccagaaaccataaaagcaaaatgtgtttctcaggca
actgatgatgcttgtcttttgaaccagtgtgattctgtagtgttaaatggaataccaaca
aatgaaataatagtctccacttcagaggaccctttagctggaggtgatccaatagtacat
cctatagaggtggcaactttgaaagagggagaatctgaatccaacagtgatatagaggac
gataatttatttttaacacaaaatgatcctgaagatatggatttgtgttcacaagtggag
aatgataatgttaaactcattgaagtagttcatggaaaagatacagttcaggtagaagtt
tctttaagttggcctcagttggaatctttgagtggcacaaagtgtaagtacaaagattgt
gttgaagtcaggaaaaaccagagtgaatactgctcaaagcactctgaagctaaagcagca
gatgaagatgtgtttcgtaaacctggcctgcctctttctgcatctaaaccttcaagacct
tccactgcgaagatttttagctcaagaagtacttcacgaattgctaatctttccaggtct
ttggaaaatgctacagcacttccaccagctctaaaaaataagccaaatggggtacaatct
attttgaaagtaccacaggcagctcctataatatttcagaagccagtgggggaaatgaag
agtttgtgcaatgttcttcatcctcagactccagataattctaacaggcaaggttacaaa
cttctgtttggtgagaacaaatctttttcaacttcctctccagtaaacattctgttatca
tcacagtctatctctgacacctttgttaaagaggtcttaaaatggaagtatgaaatgttt
ttgaacttcgatcagtgtgggccccctgcaagtctttgtcagtccatctcaagacctgtg
cctgtcagatttcaagattgcgaagattattttcatgtctttttccctttgatgatactg
aatacttttgaaacggtggctcaggaatggctcagctctccaaataaagagaatttctat
cagttgcatttaagaaaatttcctgctgattataaaaaatactgggagtttgtggtttat
ctggaggaatgtgaactggctaaacagctacatccaaaggaaaatgatttggtgtttttg
gttcctgagagacagaacggagagaagaaagatatagagagaaattgcatgcaggatctc
catgaatatcattgtggttatgttcacaagtttcgccgcacttcagtcatgcgtaatggg
aaatctgagtgttccctttccatccagactcaagataacctgccagccaatttaaatgag
cttgtgaagtgtattgtaatcagttctctggtaactacgcaaaggaagttgaaagccatg
tctctcttgaatggtcggaaccaactggctagagctgttctaaatccaaaccccatggac
ttctgtacaaaagatttactgactacaacgtctgagagaattattgcctacctaaaagat
ttcaacgaagaccaaaagaaagcgatagaaactgcatatgccatggtgaaacaatcacca
tcagttgccaaaatctgcctaattcatggaccacctggaacaggaaaatcaaaaactatt
gttggcctcctgtaccgcttgctgacagagaaccagaggaaggggcattcagatgaaaac
ttcaatgccaaaatcaaacagaaccgtgtccttgtgtgtgcaccatccaatgcagctgtg
gatgaacttatgaaaaaaattatcctcggattcaaagaaaagtgtaaagacaagaagaat
cctttgggaaactgtggagatataaatttagtacgactgggtccagaaaagtctattaat
aatgaggttctaaaattcagtttggacagccaagttaaccacagaatgaaaaaagactta
ccttctcatgttcaggatatgcatagaaaaaaggattctctagatcatcaactagatgag
ctttctcgtcagcgagctttgtgccgaggtggacgggaaatacagaggcaagaattagat
gaaaaaattgccaaagtttctaaagaaaggcaggaacttgcttctaaaattaaggaggtt
caaggacgcccacagaaaacacagagtatcatcatcttagagtcccatgtcatctgctgc
acattgagcacaagtggtggtttactgctagagtctgcttttcgtgggcaagggggtgtt
cccttcagttgtgtcattgttgatgaggctgggcagtcttgtgaagttgagactcttact
ccactcatccatcgctgcaacaagcttgttctggtaggagatcctaaacagctccctccc
acagttatttctatgaaagcacaggagtatggctatgaccaatcaatgatggctcgcttc
tataaactactggaagagaacgtggaacagaacatgatcggcagactgcctattctacag
cttactgttcagtacaggatgcatccagacatatgtctcttcccttctaattatatttat
aacagaaccttgaaaacaaatagacagacagaaacctttcgatgttcatcagactggccg
tttcaaccttaccttgtgtttgatgtcggagatggttcagaaagacgggataatgactca
tatgtaaatgttcaagaaataaaactggtgatggaaataattaagcttattaaagacaaa
agaagggatgttacttttcgaaacattggcataataacccattacaaggcccagaagaca
atgattcagaaggatttggacaaagagtttgatagaaaaggaccagcagaagtagatact
gtggatgctttccagggtcgtcagaaggattgtgttattgttacatgtgttagagcaaat
gccatgcaaggctcaattggattcctggcaagtttgcagaggttgaatgtcaccattaca
cgagccaagtacagcctcttcatccttggacatttaaggaccctgatggaaaatcagcat
tggaatcacctgattcaggatgctcagaagcgtggtgccattattaagacgtgcgacaaa
aactatagacatgatgcaatgaagattctgaaactcaagcctgtactgcagagaagtctg
actcacccccctaccatagccccagaggtgtccagaccacagagtggcttgcccagcaac
agtctagacagtggatttgtttctcctctataccacacaccccctgactgcggtgaagct
gctgttacttcaaaggatcctgaaaggctgcctgttcaggacttacttcgggacccacga
ctgctcaggaggatgggcgctgatgccaatggaaaattcctaagggatccacaatcctcg
agcccccagcatcctggagcaacacctcctgtgggcgagccaagctttcctatccctcag
caggatctgggtagtggtgtacagcagtccacggggactgctccgagcagccacaagcct
cacgtgcagtgtgagcctccagctgccagtgctgatgcttccaatagtaagagaaagtgt
agtgacctggaagaggggctcagtcacaggagagagaccaggactctcagtgaagaggag
caggagaagcatggctctgtgccccatcacaccaacaggaactctgagtgggacaagaag
agactggagagggaggaggacagcagttccaagaaaagaaaactttcatag
DBGET
integrated database retrieval system
