Propithecus coquereli (Coquerel's sifaka): 105807810
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Entry
105807810 CDS
T08746
Symbol
TYK2
Name
(RefSeq) non-receptor tyrosine-protein kinase TYK2
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
pcoq
Propithecus coquereli (Coquerel's sifaka)
Pathway
pcoq04217
Necroptosis
pcoq04380
Osteoclast differentiation
pcoq04620
Toll-like receptor signaling pathway
pcoq04621
NOD-like receptor signaling pathway
pcoq04630
JAK-STAT signaling pathway
pcoq04658
Th1 and Th2 cell differentiation
pcoq04659
Th17 cell differentiation
pcoq05145
Toxoplasmosis
pcoq05160
Hepatitis C
pcoq05161
Hepatitis B
pcoq05162
Measles
pcoq05164
Influenza A
pcoq05165
Human papillomavirus infection
pcoq05167
Kaposi sarcoma-associated herpesvirus infection
pcoq05168
Herpes simplex virus 1 infection
pcoq05169
Epstein-Barr virus infection
pcoq05171
Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:
pcoq00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
105807810 (TYK2)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
105807810 (TYK2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
105807810 (TYK2)
04621 NOD-like receptor signaling pathway
105807810 (TYK2)
04658 Th1 and Th2 cell differentiation
105807810 (TYK2)
04659 Th17 cell differentiation
105807810 (TYK2)
09158 Development and regeneration
04380 Osteoclast differentiation
105807810 (TYK2)
09160 Human Diseases
09172 Infectious disease: viral
05161 Hepatitis B
105807810 (TYK2)
05160 Hepatitis C
105807810 (TYK2)
05171 Coronavirus disease - COVID-19
105807810 (TYK2)
05164 Influenza A
105807810 (TYK2)
05162 Measles
105807810 (TYK2)
05168 Herpes simplex virus 1 infection
105807810 (TYK2)
05167 Kaposi sarcoma-associated herpesvirus infection
105807810 (TYK2)
05169 Epstein-Barr virus infection
105807810 (TYK2)
05165 Human papillomavirus infection
105807810 (TYK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
105807810 (TYK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pcoq01001
]
105807810 (TYK2)
Enzymes [BR:
pcoq01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
105807810 (TYK2)
Protein kinases [BR:
pcoq01001
]
Non-receptor tyrosine kinases
JAK family [OT]
105807810 (TYK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Jak1_Phl
FERM_F2
FERM_F1
SH2_1
Kdo
Kinase-like
ABC1
FANCA_interact
Motif
Other DBs
NCBI-GeneID:
105807810
NCBI-ProteinID:
XP_012496732
Ensembl:
ENSPCOG00000007085
LinkDB
All DBs
Position
Unknown
AA seq
1190 aa
AA seq
DB search
MPLCQRRGSRGSKPDVNGAQPLAAMGGLKVLLHWAGPGGGEPWVTFSEGSLTAEEICIHI
AHKIGITPPCVNLFALFDAQAQVWLPPNHILEISRDTSLLLYFRMRFYFRNWHGMNPQEP
AVYRCGPPGTEASSEQTEQGVQLLDPASFEYLFEQGKHEFVNDVASLWELSNEEEIHHFK
NESLGMAFLHLCHLALHRGVPLEEVAKKISFKDCIPRSFRRQIRQHNVLTRLRLRNVFRK
FIRAFQPGLLSQQVVMVKYLATLERLAPRFGTERLPVCHLRLLAQAEVEPCYTLDSGQAP
TDPSPESAAGPSTHEVLVAGTSGIQWRPIQPEGSSGGGGSSNISGSIGRNPHASLSGKKA
KVHEAGDLPVDGPREPPWAYFCDFRDITHVVLKESRVSIHRQDNKCLEFSLPSRAKALSF
VSLVDGYFRLTADSSHYLCHEVAPPRLLMSIQDGIHGPLLEPFVQAKLRPEDGLYLMHWS
TSHLYRLILTVAQRGQAPGHAQSLHLRKFPIEQRAGAFVLEGWGRPFPSVRELRAALQGC
SLRAGDDCFSLRRCCLPRPGEISNLIVMRGPRASSRQLNLSQLSFHRVGQDEITQLSHLG
QGTRTNVYEGILQVEGGDPEEGKVDSRDPLAPGGNCGQKLRVVLKVLDPSHHDIALAFYE
TASLMSQVSHVHLAFVHGVCVRGSENIMVTEYVEHGPLDVWLRRERGHVPVAWKVVVAQQ
LASALSYLEDKNLVHGNVCGRNVLLARPGLAEGTSPFIKLSDPGVGVSALSREEKVERIP
WMAPECLPGGANSLSTAADKWGFGATLLEICFDGEAPLQGRGPSEKERFYQKQHRLPEPS
CPELATLTSQCLTYEPGQRPSFRTILRDLTRLQPHNLADVVTVNPDSPASDPTVFHKRYL
KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQLRSGWRREIDILRTLYHE
HIVKYKGCCEDQGEKSVQLVMEYVPLGSLRDYLPRHSVGLAQLLLFAQQICEGMAYLHAQ
HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYCVREDGDSPVFWYAPECLKEGK
FYYASDVWSFGVTLYELLTHCDSSQSPPSKFIELIGHTQGQMTVLRLMELLERGERLPRP
DRCPPEIYLFMKNCWETEASFRPTFQNLIPILKTVQEKYRSQAPSVFSVC
NT seq
3573 nt
NT seq
+upstream
nt +downstream
nt
atgcctctgtgccaacggcggggctccaggggcagcaagcccgatgtgaacggagcgcag
cctctggctgccatgggaggcctgaaggtgcttttgcactgggctggccctggtggcggg
gagccctgggtcaccttcagcgagggctcgctgactgcagaggagatctgcatccatatc
gcgcacaaaatcggcatcactcctccctgtgtcaatctctttgccctcttcgatgcccaa
gctcaagtctggctgcccccaaaccacatcctagagatctccagggacacaagcctgttg
ctgtatttccgcatgaggttttatttccggaactggcatggcatgaatcctcaggagcca
gccgtgtaccgctgcgggcccccaggcaccgaggcttcctcagaacagacagagcagggg
gtgcaactcctggacccagcctcgtttgagtacctctttgagcagggcaagcacgagttt
gtgaatgatgtagcatcactgtgggagctctcaaacgaggaggagatccaccactttaag
aatgagagcctgggcatggcttttctgcacctctgccaccttgctctccaccgcggtgtc
cccctggaggaggtggccaagaagatcagcttcaaggactgcatcccacgctccttccgg
aggcagatccggcagcacaacgtgctgacgcggctgcgcctgcgcaatgtcttccgcaag
ttcatccgggcctttcagccgggcctcctctcccagcaggtggtcatggtcaaatacctg
gccacgctggagcggctggcgccccgcttcggcacggagcgcctgccggtgtgccacctg
cggctgctggcccaggccgaggtggagccctgctacaccctggacagcgggcaggccccc
acggaccccagccctgagtctgctgccgggccctccacccacgaggtgctggtggcaggc
accagcggcatccagtggcgacctatacagccggagggctctagtggcggtggtggcagc
agcaacatcagtggcagcatcggcaggaatccccatgccagcctgtctgggaagaaagcc
aaggtgcacgaggcgggcgacctgccagtggacgggccgcgggagccgccgtgggcctac
ttctgcgacttccgggacatcacccacgtggtgctcaaagagagccgcgtcagcatccat
cggcaggacaacaagtgcctggagttcagcctgccctcccgggccaaggccctgtccttc
gtgtcgctggtggatggctatttccgcctgacagctgactccagccactacctgtgccac
gaggtggcccccccacggctgctgatgagcattcaggatggcatccacggccccctgctg
gagccgtttgtgcaggccaagctgcggcccgaggacggcctgtacctcatgcactggagc
acgagccacctctaccgcctcatcctcacggtggcccagcgtggccaggcccccggccac
gcacagagcctgcacctccgcaagttccccatcgagcagcgggccggggccttcgtgctg
gagggctggggccgccccttccccagcgtgcgggagctgcgcgccgccttgcagggctgc
tcgctgcgggccggggacgactgcttctctttgcgccgctgctgccttccccggccggga
gaaatctccaacctcattgtcatgcgggggcctcgggccagcagcaggcagctcaacctc
agccagctcagcttccaccgtgtcggccaggacgagatcacccagctgtcccacttgggc
cagggcacgaggaccaacgtgtatgagggtatcctgcaagtagagggcggggaccccgag
gagggcaaggtggacagcagggaccccctcgcgcccggcgggaactgcgggcagaagctg
cgagtggtgctcaaagtgctggatcccagtcaccacgacattgccctggccttctacgag
acggccagcctcatgagccaggtgtcccacgtgcacctggcctttgtgcacggcgtctgc
gtgcgcggctctgagaacatcatggtgacggagtacgtggaacacgggcccctagacgtg
tggctgcggcgagagagaggccacgtgcctgtggcctggaaggtggtggtcgcccagcag
ctggccagcgccctcagctacttggaggacaagaacttggttcacggtaacgtgtgtggc
cggaacgttctgctggcacggccagggctggcggaaggcaccagccccttcatcaagctg
agtgacccaggcgtgggcgtgagtgccctctccagggaggagaaggtggagcggatcccg
tggatggcccccgagtgtctgcctggcggagccaacagcctgagcaccgccgccgacaag
tggggctttggtgccaccctcctagagatctgcttcgatggggaagcacccctccagggc
cgaggcccctccgagaaagagcgtttctatcagaagcagcaccggctgcctgagccctcg
tgccctgagctggccacactcaccagtcagtgcctgacctacgagccaggccagaggccg
tcatttcgcaccatcctgcgcgacctcactcggctgcagccacacaatcttgctgacgtt
gtgactgtaaacccggactcgccggcgtcagaccctacggttttccacaagcgctatttg
aaaaagatccgggatttgggcgagggtcacttcggcaaggtcagcttgtactgctacgac
ccgaccaacgacggcactggcgagatggtggctgtgaaagccctcaaggcggactgcggc
ccccagctccgctccggctggaggcgggagatagacatcctgcgcacgctctaccacgag
cacatcgtcaagtacaagggctgctgcgaggaccaaggcgagaagtcagtgcagctcgtc
atggagtatgtgcccctgggcagcctccgagactacctgccccggcacagcgtcgggctg
gcccagctgctgctcttcgcccagcagatctgcgagggcatggcctacctgcacgcgcag
cactacatccaccgagacctcgctgcgcgcaacgtgctgctagacaacgacaggctggtc
aagatcggggactttggcctagccaaggccgtgcccgaaggccacgagtactactgcgtg
cgcgaggatggggacagccccgtgttctggtatgccccagaatgcctgaaggagggtaag
ttctactatgcgtccgacgtctggtccttcggggtcaccctgtatgagctgctaacacac
tgcgactccagccagagccccccatcgaaattcattgagctcataggccacacccagggc
cagatgacggtgctgagactcatggagctgctggaacgaggggaaaggctgccccggcct
gacagatgtccccctgagatctatcttttcatgaagaactgctgggagacagaggcctcc
ttccgccccaccttccagaatctcatacccatcctcaagacagtccaggagaaataccga
agccaggccccttcggtgttcagtgtgtgctga
DBGET
integrated database retrieval system
