KEGG   Propithecus coquereli (Coquerel's sifaka): 105810397
Entry
105810397         CDS       T08746                                 
Symbol
AKT3
Name
(RefSeq) RAC-gamma serine/threonine-protein kinase isoform X1
  KO
K04456  RAC serine/threonine-protein kinase [EC:2.7.11.1]
Organism
pcoq  Propithecus coquereli (Coquerel's sifaka)
Pathway
pcoq01521  EGFR tyrosine kinase inhibitor resistance
pcoq01522  Endocrine resistance
pcoq01524  Platinum drug resistance
pcoq04010  MAPK signaling pathway
pcoq04012  ErbB signaling pathway
pcoq04014  Ras signaling pathway
pcoq04015  Rap1 signaling pathway
pcoq04022  cGMP-PKG signaling pathway
pcoq04024  cAMP signaling pathway
pcoq04062  Chemokine signaling pathway
pcoq04066  HIF-1 signaling pathway
pcoq04068  FoxO signaling pathway
pcoq04071  Sphingolipid signaling pathway
pcoq04072  Phospholipase D signaling pathway
pcoq04140  Autophagy - animal
pcoq04150  mTOR signaling pathway
pcoq04151  PI3K-Akt signaling pathway
pcoq04152  AMPK signaling pathway
pcoq04210  Apoptosis
pcoq04211  Longevity regulating pathway
pcoq04213  Longevity regulating pathway - multiple species
pcoq04218  Cellular senescence
pcoq04261  Adrenergic signaling in cardiomyocytes
pcoq04370  VEGF signaling pathway
pcoq04371  Apelin signaling pathway
pcoq04380  Osteoclast differentiation
pcoq04510  Focal adhesion
pcoq04550  Signaling pathways regulating pluripotency of stem cells
pcoq04611  Platelet activation
pcoq04613  Neutrophil extracellular trap formation
pcoq04620  Toll-like receptor signaling pathway
pcoq04625  C-type lectin receptor signaling pathway
pcoq04630  JAK-STAT signaling pathway
pcoq04660  T cell receptor signaling pathway
pcoq04662  B cell receptor signaling pathway
pcoq04664  Fc epsilon RI signaling pathway
pcoq04666  Fc gamma R-mediated phagocytosis
pcoq04668  TNF signaling pathway
pcoq04722  Neurotrophin signaling pathway
pcoq04725  Cholinergic synapse
pcoq04728  Dopaminergic synapse
pcoq04810  Regulation of actin cytoskeleton
pcoq04910  Insulin signaling pathway
pcoq04914  Progesterone-mediated oocyte maturation
pcoq04915  Estrogen signaling pathway
pcoq04917  Prolactin signaling pathway
pcoq04919  Thyroid hormone signaling pathway
pcoq04920  Adipocytokine signaling pathway
pcoq04922  Glucagon signaling pathway
pcoq04923  Regulation of lipolysis in adipocytes
pcoq04926  Relaxin signaling pathway
pcoq04929  GnRH secretion
pcoq04931  Insulin resistance
pcoq04932  Non-alcoholic fatty liver disease
pcoq04933  AGE-RAGE signaling pathway in diabetic complications
pcoq04935  Growth hormone synthesis, secretion and action
pcoq04936  Alcoholic liver disease
pcoq04973  Carbohydrate digestion and absorption
pcoq05010  Alzheimer disease
pcoq05017  Spinocerebellar ataxia
pcoq05132  Salmonella infection
pcoq05135  Yersinia infection
pcoq05142  Chagas disease
pcoq05145  Toxoplasmosis
pcoq05152  Tuberculosis
pcoq05160  Hepatitis C
pcoq05161  Hepatitis B
pcoq05162  Measles
pcoq05163  Human cytomegalovirus infection
pcoq05164  Influenza A
pcoq05165  Human papillomavirus infection
pcoq05166  Human T-cell leukemia virus 1 infection
pcoq05167  Kaposi sarcoma-associated herpesvirus infection
pcoq05168  Herpes simplex virus 1 infection
pcoq05169  Epstein-Barr virus infection
pcoq05170  Human immunodeficiency virus 1 infection
pcoq05200  Pathways in cancer
pcoq05205  Proteoglycans in cancer
pcoq05207  Chemical carcinogenesis - receptor activation
pcoq05208  Chemical carcinogenesis - reactive oxygen species
pcoq05210  Colorectal cancer
pcoq05211  Renal cell carcinoma
pcoq05212  Pancreatic cancer
pcoq05213  Endometrial cancer
pcoq05214  Glioma
pcoq05215  Prostate cancer
pcoq05218  Melanoma
pcoq05220  Chronic myeloid leukemia
pcoq05221  Acute myeloid leukemia
pcoq05222  Small cell lung cancer
pcoq05223  Non-small cell lung cancer
pcoq05224  Breast cancer
pcoq05225  Hepatocellular carcinoma
pcoq05226  Gastric cancer
pcoq05230  Central carbon metabolism in cancer
pcoq05231  Choline metabolism in cancer
pcoq05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
pcoq05415  Diabetic cardiomyopathy
pcoq05417  Lipid and atherosclerosis
pcoq05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pcoq00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    105810397 (AKT3)
   04012 ErbB signaling pathway
    105810397 (AKT3)
   04014 Ras signaling pathway
    105810397 (AKT3)
   04015 Rap1 signaling pathway
    105810397 (AKT3)
   04370 VEGF signaling pathway
    105810397 (AKT3)
   04371 Apelin signaling pathway
    105810397 (AKT3)
   04630 JAK-STAT signaling pathway
    105810397 (AKT3)
   04668 TNF signaling pathway
    105810397 (AKT3)
   04066 HIF-1 signaling pathway
    105810397 (AKT3)
   04068 FoxO signaling pathway
    105810397 (AKT3)
   04072 Phospholipase D signaling pathway
    105810397 (AKT3)
   04071 Sphingolipid signaling pathway
    105810397 (AKT3)
   04024 cAMP signaling pathway
    105810397 (AKT3)
   04022 cGMP-PKG signaling pathway
    105810397 (AKT3)
   04151 PI3K-Akt signaling pathway
    105810397 (AKT3)
   04152 AMPK signaling pathway
    105810397 (AKT3)
   04150 mTOR signaling pathway
    105810397 (AKT3)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    105810397 (AKT3)
  09143 Cell growth and death
   04210 Apoptosis
    105810397 (AKT3)
   04218 Cellular senescence
    105810397 (AKT3)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    105810397 (AKT3)
   04550 Signaling pathways regulating pluripotency of stem cells
    105810397 (AKT3)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    105810397 (AKT3)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    105810397 (AKT3)
   04613 Neutrophil extracellular trap formation
    105810397 (AKT3)
   04620 Toll-like receptor signaling pathway
    105810397 (AKT3)
   04625 C-type lectin receptor signaling pathway
    105810397 (AKT3)
   04660 T cell receptor signaling pathway
    105810397 (AKT3)
   04662 B cell receptor signaling pathway
    105810397 (AKT3)
   04664 Fc epsilon RI signaling pathway
    105810397 (AKT3)
   04666 Fc gamma R-mediated phagocytosis
    105810397 (AKT3)
   04062 Chemokine signaling pathway
    105810397 (AKT3)
  09152 Endocrine system
   04910 Insulin signaling pathway
    105810397 (AKT3)
   04922 Glucagon signaling pathway
    105810397 (AKT3)
   04923 Regulation of lipolysis in adipocytes
    105810397 (AKT3)
   04920 Adipocytokine signaling pathway
    105810397 (AKT3)
   04929 GnRH secretion
    105810397 (AKT3)
   04915 Estrogen signaling pathway
    105810397 (AKT3)
   04914 Progesterone-mediated oocyte maturation
    105810397 (AKT3)
   04917 Prolactin signaling pathway
    105810397 (AKT3)
   04926 Relaxin signaling pathway
    105810397 (AKT3)
   04935 Growth hormone synthesis, secretion and action
    105810397 (AKT3)
   04919 Thyroid hormone signaling pathway
    105810397 (AKT3)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    105810397 (AKT3)
  09154 Digestive system
   04973 Carbohydrate digestion and absorption
    105810397 (AKT3)
  09156 Nervous system
   04725 Cholinergic synapse
    105810397 (AKT3)
   04728 Dopaminergic synapse
    105810397 (AKT3)
   04722 Neurotrophin signaling pathway
    105810397 (AKT3)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    105810397 (AKT3)
  09149 Aging
   04211 Longevity regulating pathway
    105810397 (AKT3)
   04213 Longevity regulating pathway - multiple species
    105810397 (AKT3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    105810397 (AKT3)
   05205 Proteoglycans in cancer
    105810397 (AKT3)
   05207 Chemical carcinogenesis - receptor activation
    105810397 (AKT3)
   05208 Chemical carcinogenesis - reactive oxygen species
    105810397 (AKT3)
   05230 Central carbon metabolism in cancer
    105810397 (AKT3)
   05231 Choline metabolism in cancer
    105810397 (AKT3)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    105810397 (AKT3)
  09162 Cancer: specific types
   05210 Colorectal cancer
    105810397 (AKT3)
   05212 Pancreatic cancer
    105810397 (AKT3)
   05225 Hepatocellular carcinoma
    105810397 (AKT3)
   05226 Gastric cancer
    105810397 (AKT3)
   05214 Glioma
    105810397 (AKT3)
   05221 Acute myeloid leukemia
    105810397 (AKT3)
   05220 Chronic myeloid leukemia
    105810397 (AKT3)
   05218 Melanoma
    105810397 (AKT3)
   05211 Renal cell carcinoma
    105810397 (AKT3)
   05215 Prostate cancer
    105810397 (AKT3)
   05213 Endometrial cancer
    105810397 (AKT3)
   05224 Breast cancer
    105810397 (AKT3)
   05222 Small cell lung cancer
    105810397 (AKT3)
   05223 Non-small cell lung cancer
    105810397 (AKT3)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    105810397 (AKT3)
   05170 Human immunodeficiency virus 1 infection
    105810397 (AKT3)
   05161 Hepatitis B
    105810397 (AKT3)
   05160 Hepatitis C
    105810397 (AKT3)
   05164 Influenza A
    105810397 (AKT3)
   05162 Measles
    105810397 (AKT3)
   05168 Herpes simplex virus 1 infection
    105810397 (AKT3)
   05163 Human cytomegalovirus infection
    105810397 (AKT3)
   05167 Kaposi sarcoma-associated herpesvirus infection
    105810397 (AKT3)
   05169 Epstein-Barr virus infection
    105810397 (AKT3)
   05165 Human papillomavirus infection
    105810397 (AKT3)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    105810397 (AKT3)
   05135 Yersinia infection
    105810397 (AKT3)
   05152 Tuberculosis
    105810397 (AKT3)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    105810397 (AKT3)
   05142 Chagas disease
    105810397 (AKT3)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    105810397 (AKT3)
   05017 Spinocerebellar ataxia
    105810397 (AKT3)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    105810397 (AKT3)
   05418 Fluid shear stress and atherosclerosis
    105810397 (AKT3)
   05415 Diabetic cardiomyopathy
    105810397 (AKT3)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    105810397 (AKT3)
   04932 Non-alcoholic fatty liver disease
    105810397 (AKT3)
   04931 Insulin resistance
    105810397 (AKT3)
   04933 AGE-RAGE signaling pathway in diabetic complications
    105810397 (AKT3)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    105810397 (AKT3)
   01524 Platinum drug resistance
    105810397 (AKT3)
   01522 Endocrine resistance
    105810397 (AKT3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:pcoq01001]
    105810397 (AKT3)
Enzymes [BR:pcoq01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     105810397 (AKT3)
Protein kinases [BR:pcoq01001]
 Serine/threonine kinases: AGC group
  AKT/PKB family
   105810397 (AKT3)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr PH Pkinase_C Kinase-like PH_20 ABC1 PH_11
Other DBs
NCBI-GeneID: 105810397
NCBI-ProteinID: XP_012499834
Ensembl: ENSPCOG00000026902
UniProt: A0A2K6GQN6
LinkDB
Position
Unknown
AA seq 479 aa
MSDVTIVKEGWVQKRGEYIKNWRPRYFLLKTDGSFIGYKEKPQDVDLPYPLNNFSVAKCQ
LMKTERPKPNTFIIRCLQWTTVIERTFHVDTPEEREEWTEAIQAVADRLQRQEEERMNCS
PTSQIDNIGEEEMDASTTHHKRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILK
KEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRE
RVFSEDRTRFYGAEIVSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDA
ATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILM
EDIKFPRTLSSDAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKKLVP
PFKPQVTSETDTRYFDEEFTAQTITITPPEKYDEDGMDCMDNERRPHFPQFSYSASGRE
NT seq 1440 nt   +upstreamnt  +downstreamnt
atgagtgatgttaccattgtgaaagaaggttgggttcagaagaggggagaatatataaaa
aactggaggccaagatatttccttttgaagacagatggctcattcataggatataaagag
aaacctcaagatgtggatttaccttatcccctcaacaacttttcagtggcaaaatgccag
ttaatgaaaacagaacgaccaaagccaaacacatttataatcagatgtctgcagtggacc
actgttatagagagaacatttcatgtagatactccagaggaaagggaagaatggacagaa
gctatccaggctgtagcagacagactgcagagacaagaagaagagagaatgaattgtagt
ccaacttcacaaatcgacaatataggggaggaagagatggatgcttctacaacccatcat
aaaagaaagacaatgaacgattttgactatttgaaactactaggtaaaggcacttttggg
aaagttattttggttcgagagaaagcaagcgggaaatattatgctatgaagattctgaag
aaagaagtcattattgcaaaggatgaagtggcacacactctaactgaaagcagagtgtta
aagaacactagacatccctttttgacatccttgaaatattccttccagacaaaagaccgt
ttgtgttttgtgatggaatatgttaatgggggagagctgtttttccatttgtcgagagag
cgggtgttctctgaggaccgtacacgtttctatggtgcagaaattgtctctgccttggac
tatctacattccggaaagattgtgtaccgtgatctcaagttggagaatttgatgctggat
aaagatggccacataaaaattacagattttggactttgcaaagaagggatcacagatgca
gccaccatgaagacattctgtggtacaccggaatatcttgcaccagaggtgttagaagat
aacgactatggccgagcggtggactggtggggcctaggggttgtcatgtatgaaatgatg
tgtgggaggttacctttctacaaccaggatcacgagaaactttttgaactaatactaatg
gaagacattaaatttcctcgaacactctcttcagatgcaaaatcattgctttcagggctc
ttgatcaaggatccaaataaacgccttggtggaggaccagatgatgcaaaagaaattatg
agacacagtttcttttctggagtaaactggcaagatgtatatgataaaaagcttgtacct
ccttttaagcctcaagtaacatctgaaacagataccaggtattttgatgaagaatttaca
gctcagactattacaataacaccacctgaaaaatatgatgaggatggtatggactgcatg
gacaatgagaggcggccgcatttccctcaattttcctactctgcaagtggacgagaataa

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