Propithecus coquereli (Coquerel's sifaka): 105810544
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Entry
105810544 CDS
T08746
Symbol
TOP2B
Name
(RefSeq) DNA topoisomerase 2-beta isoform X1
KO
K03164
DNA topoisomerase II [EC:
5.6.2.2
]
Organism
pcoq
Propithecus coquereli (Coquerel's sifaka)
Pathway
pcoq01524
Platinum drug resistance
Brite
KEGG Orthology (KO) [BR:
pcoq00001
]
09160 Human Diseases
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
105810544 (TOP2B)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
pcoq03032
]
105810544 (TOP2B)
03036 Chromosome and associated proteins [BR:
pcoq03036
]
105810544 (TOP2B)
Enzymes [BR:
pcoq01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.2 DNA topoisomerase (ATP-hydrolysing)
105810544 (TOP2B)
DNA replication proteins [BR:
pcoq03032
]
Eukaryotic type
DNA Topoisomerases
105810544 (TOP2B)
Chromosome and associated proteins [BR:
pcoq03036
]
Eukaryotic type
Chromosome condensation proteins
Other regulators of chromosome condensation
105810544 (TOP2B)
Centrosome formation proteins
Centriole proteins
105810544 (TOP2B)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
DNA_topoisoIV
TOPRIM_C
DNA_gyraseB
DTHCT
Toprim
HATPase_c
DUF7180
Motif
Other DBs
NCBI-GeneID:
105810544
NCBI-ProteinID:
XP_012500005
Ensembl:
ENSPCOG00000009804
UniProt:
A0A2K6ENM3
LinkDB
All DBs
Position
Unknown
AA seq
1623 aa
AA seq
DB search
MAKSGGGGAGAGAGGNGALTWVTLFDQNNAAKNEESETANKNDSSKKLSVERVYQKKTQL
EHILLRPDTYIGSVEPLTQVMWVYDEDVGMNCREVTFVPGLYKIFDEILVNAADNKQRDK
NMTCIKVSIDPESNIISIWNNGKGIPVVEHKVEKVYVPALIFGQLLTSSNYDDDEKKVTG
GRNGYGAKLCNIFSTKFTVETACKEYKHSFKQTWMNNMMKTSEAKIKHFDGEDYTCITFQ
PDLPKFKMEKLDKDIVALMTRRAYDLAGSCKGVKVMFNGKKLPVNGFRSYVDLYVKDKLD
ETGVALKVIHELANERWDVCLTLSEKGFQQISFVNSIATTKGGRHVDYVVDQVVGKLIEV
VKKKNKAGVSVKPFQVKNHMWVFINCLIENPTFDSQTKENMTLQPKSFGSKCQLSEKFFK
AASNCGIVESILNWVKFKAQTQLNKKCSSVKYSKIKGIPKLDDANDAGGKHSLECTLILT
EGDSAKSLAVSGLGVIGRDRYGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKK
SYDDAESLKTLRYGKIMIMTDQDQDGSHIKGLLINFIHHNWPSLLKHGFLEEFITPIVKA
SKNKQELSFYSIPEFDEWKKHIENQKAWKIKYYKGLGTSTAKEAKEYFADMERHRILFRY
AGPEDDAAITLAFSKKKIDDRKEWLTNFMEDRRQRRLHGLPEQFLYGTATKHLTYNDFIN
KELILFSNSDNERSIPSLVDGFKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSAYHHG
EQALMMTIVNLAQNFVGSNNINLLQPIGQFGTRLHGGKDAASPRYIFTMLSSLARLLFPA
VDDNLLKFLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWACKLPNYDAREIVNNVRRML
DGLDPHPMLPNYKNFKGTIQELGQNQYAVSGEIFVVDRNTVEITELPVRTWTQVYKEQVL
EPMLNGTDKTPALISDYKEYHTDTTVKFVVKMTEEKLAQAEAAGLHKVFKLQTTLTCNSM
VLFDHMGCLKKYETVQDILKEFFDLRLSYYGLRKEWLVGMLGAESTKLNNQARFILEKIQ
GKITIENRSKKDLIQMLVQRGYESDPVKAWKEAQEKAAEEEETQNLHDDSSSDSGTPSGP
DFNYILNMSLWSLTKEKVEELIKQRDSKGREVNDLKRKSPSDLWKEDLAAFVEELEKVEA
QEQEDILAGMSGKAIKGKVGKPKVKKLQLEETMPSPYGRRIIPEITAMKADASKKLLKRK
KGDLDTTVVKVEFDEEFSGTPVEGTGEEALTPSAPLSKGPKPKRERKEPGTRVRKTPTSS
GKPAAKKVKKRNPWSDDESKSESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEEDDD
ADDDDDNNDLEELKVKASPITNDGEDEFVPSDGLDKDEYTFSPGKSKATPEKSSHDKKSQ
DFGNLFSFPSYSQKSEDDSAKFDSNEEDSASVFSPSFGLKQTDKIPSKTVAAKKGKPSSD
TASKPKRAPKQKKIVETVNSDSDSEFGIPKKTTAPKGKGRGAKKRKASGSENEGDYNPAR
KIPKTTSKKPKKTSFDQDSDVDIFPSDFTSEPPSLPRTGRVRKEVKYFTESDEEEDVDFA
MFN
NT seq
4872 nt
NT seq
+upstream
nt +downstream
nt
atggccaagtcgggtggcggcggagcgggagccggcgcgggcggcaacggggcgctgacc
tgggtgactctttttgatcagaacaatgctgcaaaaaatgaggagtcagagaccgcaaac
aaaaatgattcttcaaagaagttgtctgttgagagagtgtatcagaagaagacacaactt
gaacatattcttcttcgtcctgatacatacattgggtcagtggagccattgacccaggta
atgtgggtgtatgatgaagatgtagggatgaattgcagagaggttacctttgtgccaggt
ttatacaagatctttgatgaaattttggttaatgctgcagacaataaacagagggataag
aacatgacctgtattaaagtttctattgatcctgaatctaacattataagcatttggaat
aatgggaaaggcattccagtagtagaacacaaagtagagaaagtttatgttcctgcttta
atttttggacagcttttaacatctagtaactatgatgatgatgagaaaaaagttacaggt
ggtcgcaatggttatggtgcaaaactttgtaacattttcagtacaaagtttactgtagaa
acagcttgcaaagagtacaaacacagttttaagcagacatggatgaataatatgatgaag
acttctgaagccaaaattaaacattttgatggtgaagattacacatgtataacattccaa
ccagacctgcccaaatttaagatggaaaaacttgataaggatattgtggccctcatgacc
agaagagcatatgatttggctggttcatgtaaaggggtcaaggtcatgtttaatggaaag
aaattgcctgtaaatggatttcgaagttatgtggatctttatgtgaaagacaaattggat
gaaactggggtggcactgaaagttattcatgaacttgcaaatgaaagatgggatgtttgt
ctcacattgagtgaaaaaggattccagcaaatcagctttgtaaatagtattgcaactaca
aaaggtggacggcacgtggattatgtagtagatcaagttgtcggtaaattgattgaagta
gttaagaaaaagaacaaggctggtgtatcagtgaaaccatttcaagtaaaaaaccacatg
tgggtttttattaattgccttattgaaaatccaacatttgattctcagaccaaggaaaac
atgactctgcagcccaaaagttttgggtccaaatgtcaactgtcagaaaaattttttaaa
gcagcctctaattgtggcattgtagaaagtatcctgaactgggtgaaatttaaggctcag
actcagctgaacaagaagtgttcctcagtaaaatacagtaaaatcaaaggtattcccaaa
ctggatgatgctaatgatgctggtggcaaacattccctggagtgtacactgatattaaca
gagggagactctgccaaatcactggctgtgtctggattaggtgtgattgggcgggacaga
tacggagtttttccgctcaggggtaaaattcttaatgtacgggaagcttctcataaacag
attatggaaaatgcagaaataaacaatattattaaaatagttggtctacagtataagaag
agttatgatgatgcagaatctttgaaaaccttacgttatggaaagattatgattatgact
gatcaggatcaagatggttctcacataaaaggcctgcttattaatttcatccatcacaat
tggccatcacttttgaagcatggttttcttgaagagttcattactcctattgtaaaggcg
agcaaaaataagcaggaactttccttctacagtattcctgaatttgatgagtggaaaaaa
catatagaaaaccagaaagcctggaaaataaaatactacaaaggtttgggtaccagtaca
gctaaagaagcaaaggaatattttgctgatatggaaaggcatcgcatcttgtttagatat
gctggtcctgaagatgatgctgccattaccttggcattcagtaagaagaagattgatgac
agaaaagaatggttaacaaatttcatggaagatcggagacagcgtaggttacatggcttg
ccagagcaatttttatatggtacagcaacaaagcatttgacttacaatgatttcatcaac
aaggaattgattctcttctcaaactcagacaatgaaagatctataccatctcttgttgat
ggctttaaacctgggcaacgaaaagttttatttacttgtttcaagaggaatgataaacgt
gaagtaaaagttgcccagttggctggatctgttgctgaaatgtctgcttatcatcatgga
gaacaagcattgatgatgactattgtgaatttggctcagaactttgtgggaagtaacaac
attaacttgcttcagcctattggtcagtttggaactcggcttcatggtggcaaagatgct
gcaagccctcgttatattttcacaatgttaagctctttagcaagactgctttttcctgct
gtggacgataacttgcttaagttcctttatgatgataatcagcgtgtagagcctgagtgg
tatattcccataattccgatggttttaataaatggtgctgagggcattggcactggatgg
gcttgtaaactacccaactacgatgctagggaaattgtgaacaatgtcagacgaatgctt
gatggcttggatcctcatcccatgcttccaaactacaaaaactttaaaggcacgatccaa
gaacttggtcaaaaccagtatgcagtcagtggtgaaatatttgtagtggatagaaacaca
gtagaaattacagagcttccagttagaacttggacacaggtatacaaagaacaggtttta
gaacctatgctaaatggaacagacaaaacaccagctttaatttctgattataaagaatac
catactgatacaactgtgaaatttgtggtgaaaatgactgaagagaaactagcacaagca
gaagctgctggattgcataaagtttttaaacttcaaactactcttacttgtaattccatg
gtactctttgatcatatgggatgtctgaagaagtatgaaactgtgcaagacattctgaaa
gaattctttgatttacgattaagttattatggtttacgtaaggagtggcttgtaggcatg
ttgggagcagagtctacaaagcttaataatcaagcccgtttcattttagagaagatacaa
gggaaaattactatagagaataggtcaaagaaagatttgattcaaatgttagtccagaga
ggttatgaatctgacccagtgaaagcctggaaagaagcacaagaaaaggcagcagaagag
gaagaaacacaaaacctgcatgatgatagttcctccgattcgggaactccttcaggcccc
gattttaattatattttaaatatgtctctgtggtctcttactaaagaaaaagttgaagaa
ctgattaaacaaagagattcaaaagggcgagaggtgaatgatcttaaaagaaaatctcct
tcagatctttggaaagaagatttagcagcatttgtagaagaactggagaaagttgaagca
caagaacaagaagatattctggctggaatgtcaggaaaagcaataaaaggtaaagttggc
aagcctaaggtgaagaaacttcaactggaagagacaatgccctcaccttatgggagaaga
ataattcctgaaattaccgctatgaaggcagatgccagcaaaaagttgctgaagaggaag
aagggtgaccttgataccacagtagtaaaagtggaatttgatgaagaattcagtggaaca
ccagtagaaggtacaggagaagaggcattgaccccatcagctcctctaagtaaaggtccc
aaacccaaaagggagagaaaggagcctggtaccagggtgagaaaaacacctacatcatct
ggtaaacctgctgcaaagaaagtgaaaaaacggaatccttggtcagatgatgaatccaag
tcagaaagtgatttggaagaaacagaacctgtggttattccaagagattctttgcttagg
agagcagctgctgaaagacctaagtacacatttgatttctcagaagaagaggatgatgat
gctgatgatgatgacgacaataatgatttagaggaattgaaagttaaagcatctcctata
acaaatgatggggaagatgaatttgttccttcagatggcttagataaagatgaatatacg
ttttcaccaggcaaatcaaaagctactccagaaaaatcttcacatgacaaaaaaagtcag
gattttggaaatctcttctcatttccttcatattctcagaagtcagaagatgattcggct
aaattcgacagtaatgaagaagattctgcttcggttttttcaccatcatttggtctgaaa
caaacagataaaattccaagtaaaacagtagctgctaaaaagggaaaaccatcttcagat
acagcgtctaagcctaagagagcccccaaacagaagaaaatcgtagagactgtaaactct
gactcagattcagaatttggcattccaaagaagactacagcgccaaaaggtaaaggccga
ggggcaaagaaaaggaaagcatctggctctgaaaatgaaggtgattataaccctgccagg
aaaatacccaaaacaacaagcaagaaaccgaagaaaacatcatttgatcaggattcagat
gtggacatcttcccctcagacttcacttctgaaccaccttctctgccacggactggtcga
gttaggaaagaagtaaaatattttacagagtctgatgaagaagaagatgttgattttgca
atgtttaattaa
DBGET
integrated database retrieval system
