KEGG   Propithecus coquereli (Coquerel's sifaka): 105812191
Entry
105812191         CDS       T08746                                 
Symbol
MAPK14
Name
(RefSeq) mitogen-activated protein kinase 14
  KO
K04441  p38 MAP kinase [EC:2.7.11.24]
Organism
pcoq  Propithecus coquereli (Coquerel's sifaka)
Pathway
pcoq01522  Endocrine resistance
pcoq04010  MAPK signaling pathway
pcoq04015  Rap1 signaling pathway
pcoq04068  FoxO signaling pathway
pcoq04071  Sphingolipid signaling pathway
pcoq04114  Oocyte meiosis
pcoq04148  Efferocytosis
pcoq04218  Cellular senescence
pcoq04261  Adrenergic signaling in cardiomyocytes
pcoq04370  VEGF signaling pathway
pcoq04380  Osteoclast differentiation
pcoq04550  Signaling pathways regulating pluripotency of stem cells
pcoq04611  Platelet activation
pcoq04613  Neutrophil extracellular trap formation
pcoq04620  Toll-like receptor signaling pathway
pcoq04621  NOD-like receptor signaling pathway
pcoq04622  RIG-I-like receptor signaling pathway
pcoq04625  C-type lectin receptor signaling pathway
pcoq04657  IL-17 signaling pathway
pcoq04658  Th1 and Th2 cell differentiation
pcoq04659  Th17 cell differentiation
pcoq04660  T cell receptor signaling pathway
pcoq04664  Fc epsilon RI signaling pathway
pcoq04668  TNF signaling pathway
pcoq04670  Leukocyte transendothelial migration
pcoq04714  Thermogenesis
pcoq04722  Neurotrophin signaling pathway
pcoq04723  Retrograde endocannabinoid signaling
pcoq04728  Dopaminergic synapse
pcoq04750  Inflammatory mediator regulation of TRP channels
pcoq04912  GnRH signaling pathway
pcoq04914  Progesterone-mediated oocyte maturation
pcoq04917  Prolactin signaling pathway
pcoq04926  Relaxin signaling pathway
pcoq04932  Non-alcoholic fatty liver disease
pcoq04933  AGE-RAGE signaling pathway in diabetic complications
pcoq04935  Growth hormone synthesis, secretion and action
pcoq04936  Alcoholic liver disease
pcoq05014  Amyotrophic lateral sclerosis
pcoq05020  Prion disease
pcoq05022  Pathways of neurodegeneration - multiple diseases
pcoq05132  Salmonella infection
pcoq05133  Pertussis
pcoq05135  Yersinia infection
pcoq05140  Leishmaniasis
pcoq05142  Chagas disease
pcoq05145  Toxoplasmosis
pcoq05152  Tuberculosis
pcoq05161  Hepatitis B
pcoq05163  Human cytomegalovirus infection
pcoq05167  Kaposi sarcoma-associated herpesvirus infection
pcoq05169  Epstein-Barr virus infection
pcoq05170  Human immunodeficiency virus 1 infection
pcoq05171  Coronavirus disease - COVID-19
pcoq05205  Proteoglycans in cancer
pcoq05208  Chemical carcinogenesis - reactive oxygen species
pcoq05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
pcoq05415  Diabetic cardiomyopathy
pcoq05417  Lipid and atherosclerosis
pcoq05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pcoq00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    105812191 (MAPK14)
   04015 Rap1 signaling pathway
    105812191 (MAPK14)
   04370 VEGF signaling pathway
    105812191 (MAPK14)
   04668 TNF signaling pathway
    105812191 (MAPK14)
   04068 FoxO signaling pathway
    105812191 (MAPK14)
   04071 Sphingolipid signaling pathway
    105812191 (MAPK14)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    105812191 (MAPK14)
  09143 Cell growth and death
   04114 Oocyte meiosis
    105812191 (MAPK14)
   04218 Cellular senescence
    105812191 (MAPK14)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    105812191 (MAPK14)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    105812191 (MAPK14)
   04613 Neutrophil extracellular trap formation
    105812191 (MAPK14)
   04620 Toll-like receptor signaling pathway
    105812191 (MAPK14)
   04621 NOD-like receptor signaling pathway
    105812191 (MAPK14)
   04622 RIG-I-like receptor signaling pathway
    105812191 (MAPK14)
   04625 C-type lectin receptor signaling pathway
    105812191 (MAPK14)
   04660 T cell receptor signaling pathway
    105812191 (MAPK14)
   04658 Th1 and Th2 cell differentiation
    105812191 (MAPK14)
   04659 Th17 cell differentiation
    105812191 (MAPK14)
   04657 IL-17 signaling pathway
    105812191 (MAPK14)
   04664 Fc epsilon RI signaling pathway
    105812191 (MAPK14)
   04670 Leukocyte transendothelial migration
    105812191 (MAPK14)
  09152 Endocrine system
   04912 GnRH signaling pathway
    105812191 (MAPK14)
   04914 Progesterone-mediated oocyte maturation
    105812191 (MAPK14)
   04917 Prolactin signaling pathway
    105812191 (MAPK14)
   04926 Relaxin signaling pathway
    105812191 (MAPK14)
   04935 Growth hormone synthesis, secretion and action
    105812191 (MAPK14)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    105812191 (MAPK14)
  09156 Nervous system
   04728 Dopaminergic synapse
    105812191 (MAPK14)
   04723 Retrograde endocannabinoid signaling
    105812191 (MAPK14)
   04722 Neurotrophin signaling pathway
    105812191 (MAPK14)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    105812191 (MAPK14)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    105812191 (MAPK14)
  09159 Environmental adaptation
   04714 Thermogenesis
    105812191 (MAPK14)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    105812191 (MAPK14)
   05208 Chemical carcinogenesis - reactive oxygen species
    105812191 (MAPK14)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    105812191 (MAPK14)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    105812191 (MAPK14)
   05161 Hepatitis B
    105812191 (MAPK14)
   05171 Coronavirus disease - COVID-19
    105812191 (MAPK14)
   05163 Human cytomegalovirus infection
    105812191 (MAPK14)
   05167 Kaposi sarcoma-associated herpesvirus infection
    105812191 (MAPK14)
   05169 Epstein-Barr virus infection
    105812191 (MAPK14)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    105812191 (MAPK14)
   05135 Yersinia infection
    105812191 (MAPK14)
   05133 Pertussis
    105812191 (MAPK14)
   05152 Tuberculosis
    105812191 (MAPK14)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    105812191 (MAPK14)
   05140 Leishmaniasis
    105812191 (MAPK14)
   05142 Chagas disease
    105812191 (MAPK14)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    105812191 (MAPK14)
   05020 Prion disease
    105812191 (MAPK14)
   05022 Pathways of neurodegeneration - multiple diseases
    105812191 (MAPK14)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    105812191 (MAPK14)
   05418 Fluid shear stress and atherosclerosis
    105812191 (MAPK14)
   05415 Diabetic cardiomyopathy
    105812191 (MAPK14)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    105812191 (MAPK14)
   04932 Non-alcoholic fatty liver disease
    105812191 (MAPK14)
   04933 AGE-RAGE signaling pathway in diabetic complications
    105812191 (MAPK14)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    105812191 (MAPK14)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:pcoq01001]
    105812191 (MAPK14)
Enzymes [BR:pcoq01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     105812191 (MAPK14)
Protein kinases [BR:pcoq01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   105812191 (MAPK14)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kdo 8TM_micro NAD_binding_8
Other DBs
NCBI-GeneID: 105812191
NCBI-ProteinID: XP_012502029
Ensembl: ENSPCOG00000020496
LinkDB
Position
Unknown
AA seq 317 aa
MSQERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQ
SIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQ
KLTDDHVQFLIYQILRGLKYIHSADIIHRCTYFYFSLILPVDIWSVGCIMAELLTGRTLF
PGTDHIDQLKLILRLVGTPGAELLKKISSESARNYIQSLTQMPKMNFANVFIGANPLAVD
LLEKMLVLDSDKRITAAQALAHAYFAQYHDPDDEPVADPYDQSFESRDLLIDEWKSLTYD
EVISFVPPPLDQEEMES
NT seq 954 nt   +upstreamnt  +downstreamnt
atgtctcaggagaggcccacgttctaccggcaggagctgaacaagacaatctgggaggtg
cccgagcgttaccagaacctgtccccggtgggctccggcgcctatggctcggtgtgtgct
gcttttgacacaaaaactgggttacgtgtggcggtgaagaagctatccagaccatttcag
tccatcattcatgccaaaagaacctacagagaactgcggttacttaaacatatgaaacat
gaaaatgtgattggtctgttggatgtttttacacctgcaaggtctctggaggaattcaat
gatgtgtatctggtgacccatctcatgggggcagatctgaacaacattgtgaaatgtcag
aagcttacagatgaccatgttcagttccttatctaccaaattctccgaggtctaaagtat
atacattcagctgacataattcacaggtgcacgtacttttatttctctttaattttgcca
gttgatatttggtcagtgggatgcataatggccgagctgttgactggaagaacattgttt
cctggtacagaccatattgatcagttgaagctcattttaagactcgttggaaccccaggg
gctgagcttttgaagaaaatctcctcagagtctgcaagaaactatattcagtctttgacc
cagatgccgaagatgaactttgcgaatgtatttattggtgccaatcctttggccgtcgac
ttgctggagaagatgcttgtgttggactcagataagagaattacagcagcccaagccctt
gcacacgcctactttgctcagtaccatgaccctgatgatgagccagtggccgacccttat
gatcagtcctttgaaagcagggaccttctcatagatgagtggaaaagcctgacctacgat
gaagtcatcagctttgtgccgccaccccttgaccaagaagagatggagtcctga

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