KEGG   Propithecus coquereli (Coquerel's sifaka): 105814830
Entry
105814830         CDS       T08746                                 
Symbol
PRKAA1
Name
(RefSeq) 5'-AMP-activated protein kinase catalytic subunit alpha-1 isoform X1
  KO
K07198  5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
Organism
pcoq  Propithecus coquereli (Coquerel's sifaka)
Pathway
pcoq04068  FoxO signaling pathway
pcoq04140  Autophagy - animal
pcoq04150  mTOR signaling pathway
pcoq04151  PI3K-Akt signaling pathway
pcoq04152  AMPK signaling pathway
pcoq04211  Longevity regulating pathway
pcoq04213  Longevity regulating pathway - multiple species
pcoq04371  Apelin signaling pathway
pcoq04530  Tight junction
pcoq04710  Circadian rhythm
pcoq04714  Thermogenesis
pcoq04910  Insulin signaling pathway
pcoq04920  Adipocytokine signaling pathway
pcoq04921  Oxytocin signaling pathway
pcoq04922  Glucagon signaling pathway
pcoq04931  Insulin resistance
pcoq04932  Non-alcoholic fatty liver disease
pcoq04936  Alcoholic liver disease
pcoq05410  Hypertrophic cardiomyopathy
pcoq05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pcoq00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04371 Apelin signaling pathway
    105814830 (PRKAA1)
   04068 FoxO signaling pathway
    105814830 (PRKAA1)
   04151 PI3K-Akt signaling pathway
    105814830 (PRKAA1)
   04152 AMPK signaling pathway
    105814830 (PRKAA1)
   04150 mTOR signaling pathway
    105814830 (PRKAA1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    105814830 (PRKAA1)
  09144 Cellular community - eukaryotes
   04530 Tight junction
    105814830 (PRKAA1)
 09150 Organismal Systems
  09152 Endocrine system
   04910 Insulin signaling pathway
    105814830 (PRKAA1)
   04922 Glucagon signaling pathway
    105814830 (PRKAA1)
   04920 Adipocytokine signaling pathway
    105814830 (PRKAA1)
   04921 Oxytocin signaling pathway
    105814830 (PRKAA1)
  09149 Aging
   04211 Longevity regulating pathway
    105814830 (PRKAA1)
   04213 Longevity regulating pathway - multiple species
    105814830 (PRKAA1)
  09159 Environmental adaptation
   04710 Circadian rhythm
    105814830 (PRKAA1)
   04714 Thermogenesis
    105814830 (PRKAA1)
 09160 Human Diseases
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    105814830 (PRKAA1)
   05410 Hypertrophic cardiomyopathy
    105814830 (PRKAA1)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    105814830 (PRKAA1)
   04932 Non-alcoholic fatty liver disease
    105814830 (PRKAA1)
   04931 Insulin resistance
    105814830 (PRKAA1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:pcoq01001]
    105814830 (PRKAA1)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:pcoq04131]
    105814830 (PRKAA1)
   03029 Mitochondrial biogenesis [BR:pcoq03029]
    105814830 (PRKAA1)
Enzymes [BR:pcoq01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.31  [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase
     105814830 (PRKAA1)
Protein kinases [BR:pcoq01001]
 Serine/threonine kinases: CAMK group
  CAMKL family
   105814830 (PRKAA1)
Membrane trafficking [BR:pcoq04131]
 Autophagy
  Other autophagy associated proteins
   Others
    105814830 (PRKAA1)
Mitochondrial biogenesis [BR:pcoq03029]
 Mitochondrial quality control factors
  Regulator of mitochondrial biogenesis
   Other regulator of mitochondrial biogenesis
    105814830 (PRKAA1)
  Mitophagy factors
   Other mitophagy factors
    105814830 (PRKAA1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr AMPK_alpha_AID AdenylateSensor ABC1 Kinase-like Kdo APH
Other DBs
NCBI-GeneID: 105814830
NCBI-ProteinID: XP_012505380
Ensembl: ENSPCOG00000023955
UniProt: A0A2K6GBP0
LinkDB
Position
Unknown
AA seq 559 aa
MRRLSSWRKMATAEKQKHDGRVKIGHYILGDTLGVGTFGKVKVGKHELTGHKVAVKILNR
QKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNG
RLDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEF
LRTSCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDG
IFYTPQYLNPSVISLLKHMLQVDPMKRATIKDIREHEWFKHDLPKYLFPEDPSYSSTMID
DEALKEVCEKFECSEEEVLSCLYNRNHQDPLAVAYHLIIDNRRIMNEAKDFYLATSPPDS
FLDDHHLTRPHPERVPFLVAETPRARHTLDELNPQKSKHQGVRKAKWHLGIRSQSRPNDI
MAEVCRAIKQLDYEWKVVNPYYLRVRRKNPVTSTYSKMSLQLYQVDSRTYLLDFRSIDDE
ITEAKSGTATPQRSGSVSNYRSCQRNDSDAEAQGKSSEVSLTSSVTSLDSSPVDLTPRPG
SHTIEFFEMCANLIKILAQ
NT seq 1680 nt   +upstreamnt  +downstreamnt
atgcgcagactcagttcctggagaaagatggcgacagccgagaagcagaaacacgacggg
cgggtgaagatcggtcactacatcctgggagacacgctaggggtcggcacctttggcaaa
gtgaaggttggcaaacatgaattgactgggcataaagttgctgtgaagatactcaatcga
cagaagattcgaagcctcgatgtggtaggaaaaatccgcagagaaattcagaacctcaag
cttttcaggcatcctcatataattaaactgtaccaggtcatcagtacaccatctgatatt
ttcatggtgatggagtatgtctcaggaggagagctatttgattatatctgtaaaaatgga
aggctcgatgaaaaagaaagtcgacgtctgttccaacaaatcctttctggtgtagattat
tgtcacaggcatatggtggtccatagagatttgaaacctgaaaacgtcctgcttgatgca
catatgaatgcaaagatagctgattttggtctttcaaacatgatgtcagatggtgaattt
ttaagaacaagttgtggctcacccaactatgctgcaccagaagtaatttcaggaagatta
tatgcaggcccagaggtagatatatggagcagtggggttattctctatgctttattatgt
ggaacccttccatttgatgatgatcatgtgccaactctttttaagaagatatgtgatggg
atcttttatacccctcagtatttaaatccttctgtgattagccttctgaaacacatgctg
caggtggatcccatgaagagggccacaatcaaagatatcagggaacatgaatggtttaaa
catgaccttccaaaatatctctttcctgaggatccatcatatagttcaaccatgattgat
gatgaagccttaaaagaagtatgtgaaaaatttgagtgctcagaagaggaggttctcagc
tgcctttataatagaaatcaccaggaccctttggcagttgcctaccatctcataatagat
aacaggagaataatgaatgaagccaaagatttctacttggcgacaagcccacctgattct
tttctcgatgatcaccatctgactcggccccatcctgaaagagtaccattcttggttgct
gaaacaccaagggcacgtcatactctcgatgaattgaatccacagaaatccaaacatcaa
ggtgtaaggaaagcaaaatggcatttaggaattagaagtcaaagtcgaccaaatgatatc
atggcagaagtatgcagagcaattaaacaattggattatgaatggaaggttgtaaaccca
tattatttgcgtgtacgaaggaagaatcctgtgacaagcacatactccaaaatgagtcta
caattataccaagtggatagtagaacttacttactggattttcgtagtattgatgatgaa
attacagaagccaaatcagggactgctactccacagagatcgggatcagttagcaactat
cgatcttgccaaaggaatgattcagatgctgaggctcaaggaaaatcctcagaagtttct
cttacctcatctgtgacctcacttgactcttctcctgttgacttaactccaagacctgga
agtcacacaatagaattttttgagatgtgtgcaaatctaattaaaattcttgcacagtaa

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