Propithecus coquereli (Coquerel's sifaka): 105816534
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Entry
105816534 CDS
T08746
Symbol
SHMT2
Name
(RefSeq) serine hydroxymethyltransferase, mitochondrial
KO
K00600
glycine hydroxymethyltransferase [EC:
2.1.2.1
]
Organism
pcoq
Propithecus coquereli (Coquerel's sifaka)
Pathway
pcoq00260
Glycine, serine and threonine metabolism
pcoq00630
Glyoxylate and dicarboxylate metabolism
pcoq00670
One carbon pool by folate
pcoq01100
Metabolic pathways
pcoq01200
Carbon metabolism
pcoq01230
Biosynthesis of amino acids
pcoq01240
Biosynthesis of cofactors
pcoq01523
Antifolate resistance
pcoq04981
Folate transport and metabolism
Module
pcoq_M00141
C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:
pcoq00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00630 Glyoxylate and dicarboxylate metabolism
105816534 (SHMT2)
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
105816534 (SHMT2)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
105816534 (SHMT2)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
105816534 (SHMT2)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
105816534 (SHMT2)
Enzymes [BR:
pcoq01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.1 glycine hydroxymethyltransferase
105816534 (SHMT2)
BRITE hierarchy
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Ortholog
Paralog
GFIT
Motif
Pfam:
SHMT
Motif
Other DBs
NCBI-GeneID:
105816534
NCBI-ProteinID:
XP_012507429
Ensembl:
ENSPCOG00000024293
LinkDB
All DBs
Position
Unknown
AA seq
532 aa
AA seq
DB search
MRPTTGLLPTACYPRPELVAGPLRLRVAMLPFSLLWAAPPLRRCGQLASMAIRAQHSKAA
QTQTGEGTRGWTGQESLSDSDPEMWELLQKEKDRQCRGLELIASENFCSRAALEALGSCL
NNKYSEGYPGKRYYGGTEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAAYT
ALLQPHDRIMGLDLPDGGHLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYDQLALT
ARLFRPRLIIAGTSAYARLIDYARMREVCDEVKAHLLADMAHISGLVAAKVIPSPFKHAD
IVTTTTHKTLRGARSGLIFYRKGVRAVDPKTGREIPYTFEDQVNFAVFPSLQGGPHNHAI
AAVAVALKQACTPMFREYSLQVLKNARAMADALLQRGYSLVSGGTDNHLVLVDLRPKGLD
GARAERVLELVSITANKNTCPGDRSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGV
NIGLEVKNKTAKLQDFKSFLLKDPETSQRLAELRQQVELFARAFPMPGFDEH
NT seq
1599 nt
NT seq
+upstream
nt +downstream
nt
atgcgccctacgaccggtcttcttccgacagcttgctaccccaggccagagttggtggct
ggacccctgcgacttcgggttgcgatgctgcctttctctttgctttgggcagctccgcct
ctgcggagatgtggtcagctggccagcatggccattcgggctcagcacagcaaggcagcc
cagacgcagactggggaaggaaccaggggctggacaggccaggagagtctttcggacagt
gaccctgagatgtgggagctgctacagaaggagaaggacaggcagtgtcgtggcctggag
ctcattgcctcagagaacttctgcagccgagctgcgctggaggccctggggtcctgtctg
aacaacaagtactcggagggttatcctggcaagagatattacgggggaacagaggtagtg
gacgaaatagagctgctgtgccagcgccgggctctggaagcctttgacctggatcctgcg
cagtggggagtcaacgtccagccctactctgggtccccagccaatctagccgcctataca
gcccttctgcagcctcacgaccgaatcatggggctggacctgcctgatgggggccacctg
acccatggctacatgtctgacgtcaagcggatctcagccacatccatcttcttcgagtcc
atgccctataagctcaatcccaaaactggcctcattgactacgaccagctggcactgact
gctcgactcttccgaccccggctcatcatagctggcaccagtgcctatgctcgcctcatt
gactacgcccgcatgagagaggtgtgtgatgaggtcaaggcacacctgctggcagacatg
gctcacatcagtggcctggtggctgctaaggtgatcccctcacctttcaagcatgcagac
attgtcaccaccaccactcacaagactcttcgaggggccaggtcaggactcatcttctac
cggaagggggtgcgggctgtggaccccaagactggccgggagatcccttacacatttgag
gaccaagtcaactttgctgtgttcccatccctgcagggaggcccccacaaccatgccatt
gctgcagtagctgtggccctaaagcaggcctgtacccccatgttccgggaatactccctg
caggttctgaagaatgctcgggccatggctgacgccctactacagcgaggctactcactg
gtatccggtggcactgacaaccacctggtgctggtggacctgcggcccaagggcctggac
ggagctcgggctgagcgagtgctggagcttgtatctatcactgccaacaagaacacttgt
cctggagaccgaagtgccatcacacctgggggcctccggcttggggccccagccttgacc
tctcgacagttccgtgaggatgacttccggagagttgtagactttatagatgaaggagtc
aacattggcttggaggtgaagaacaagacagccaaactccaggatttcaaatccttcctg
ctcaaggacccagaaactagccagcgtctggctgagctcaggcagcaggtagagctgttt
gccagggccttccccatgcctggttttgatgagcactga
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