Propithecus coquereli (Coquerel's sifaka): 105820725
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Entry
105820725 CDS
T08746
Symbol
POLE
Name
(RefSeq) DNA polymerase epsilon catalytic subunit A
KO
K02324
DNA polymerase epsilon subunit 1 [EC:
2.7.7.7
]
Organism
pcoq
Propithecus coquereli (Coquerel's sifaka)
Pathway
pcoq03030
DNA replication
pcoq03410
Base excision repair
pcoq03420
Nucleotide excision repair
Brite
KEGG Orthology (KO) [BR:
pcoq00001
]
09120 Genetic Information Processing
09124 Replication and repair
03030 DNA replication
105820725 (POLE)
03410 Base excision repair
105820725 (POLE)
03420 Nucleotide excision repair
105820725 (POLE)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
pcoq03032
]
105820725 (POLE)
03400 DNA repair and recombination proteins [BR:
pcoq03400
]
105820725 (POLE)
Enzymes [BR:
pcoq01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.7 Nucleotidyltransferases
2.7.7.7 DNA-directed DNA polymerase
105820725 (POLE)
DNA replication proteins [BR:
pcoq03032
]
Eukaryotic type
DNA Replication Elongation Factors
DNA polymerase epsilon complex
105820725 (POLE)
DNA repair and recombination proteins [BR:
pcoq03400
]
Eukaryotic type
SSBR (single strand breaks repair)
BER (base exicision repair)
Long Patch-BER factors
DNA polymerase epsilon complex
105820725 (POLE)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
DUF1744
POL2_thumb
DNA_pol_B_exo1
zf_DPOE_2
zf-DPOE
DNA_pol_B
DNA_pol_B_exo2
RNase_H_2
APP_N
Motif
Other DBs
NCBI-GeneID:
105820725
NCBI-ProteinID:
XP_012512723
Ensembl:
ENSPCOG00000018993
UniProt:
A0A2K6FKS8
LinkDB
All DBs
Position
Unknown
AA seq
2284 aa
AA seq
DB search
MALRSGGRGRAEPGADGEVGRDDGSSSSVSALKRLERSQWTDKMDLRFGFERLKEPGEKT
GWLINMHPTEILDEDKRLVSAVDYYFIQDDGSRFKVALPYKPYFYIATRKGCEREVSSFL
SKKFQGKIAKVETVPKEDLDLPNHLVGLKRNYIKLSFHTVEDLVKVRKEISPAVKKNREQ
DHASDAYTAMLSSVLQGGSVITDEEEASKKIADQLDNIVDMREYDVPYHIRLSIDLKIHV
AHWYNVRHRGNALPMEITRRDDLVERPDPVVLAFDIETTKLPLKFPDAETDQIMMISYMI
DGQGYLITNREIVSEDIEDFEFTPKPEYEGPFCVFNEPDEVHLIQRWFEHVQETKPTIMV
TYNGDFFDWPFVEARAAVYGLSMHQEIGFQKDSQGEYKAPQCIHMDCLRWVKRDSYLPVG
SHNLKAAAKAKLGYDPVELDPEDMCRMATEQPQTLATYSVSDAVATYYLYMKYVHPFIFA
LCTIIPMEPDEVLRKGSGTLCEALLMVQAFHANIIFPNKQEQELNKLTADGHVLDAETYV
GGHVEALESGVFRSDIPCRFRMNPAAFDFLLQRVEKTMRHAIEEEEKVSVEQVTNFQEVC
DEIKTKLTSLKDVPNRIECPLIYHLDVGAMYPNIILTNRLQPSAMVDEATCAACDFNKPG
ANCQRKMAWQWRGEFMPASRSEYHRIQHQLESEKFPPLFPEGPARAFHELSREEQAKYEK
KRLADYCRKAYKKIHITKVEERITTICQRENSFYVDTVRAFRDRRYEFKGLHKVWKKKLS
AAVEAGDAAEVKRCKNMEVLYDSLQLAHKCILNSFYGYVMRKGARWYSMEMAGIVCFTGA
NIITQARELIEQIGRPLELDTDGIWCVLPNSFPENFVLKTTNAKKPRVTISYPGAMLNIL
VKEGFTNHQYQELAEPSSLTYVTRSENSIFFEVDGPYLAMILPASKEEGKKLKKRYAVFN
EDGSLAELKGFEVKRRGELQLIKIFQSSVFEAFLKGSTLEEVYGSVAKVADYWLDVLYSK
AANMPDSELFELISENRSMSRKLEDYGEQKSTSISTAKRLAEFLGDQMVKDAGLSCRYII
SRKPEGSPVTERAIPLAIFQAEPTVRKHFLRKWLKSSSLQDFDIRTILDWDYYIERLGSA
IQKIITIPAALQQVKNPVPRVKHPDWLHRKLLEKNDIYKQKKISELFVLEGRRQVVMAQA
PEGSPRPSVADMEDFGLTQLPHPAVPVATKRKRVLWESQEESQDLALTVPWQEILGQPPA
LGTTQAEWLVWLGFHKKKWQLQARQRLARRKRQRLESGSMLRPGAIRDGPATGLGSFLRK
TARSVLDLPWQIVQISETSQAGLFRLWAVIGSDLHCIKLSIPRVFYVNQRVAKAEDGPSY
RKVNRVLPRSNVVYNLYEYSVPEDMYQEHINEINTELSAPDIEGVYETQVPLLFRALVQL
GCVCVVNKQLVRHLSGWEADTFALGHLEMRSLAQFSYLEPGSIRHIYLYHHSQGHKALFG
LFIPSQRRASVFVLDTVRSNQMPSLSALYSAEHSLLLDRVGPELLPPSKHTFEVRAETDL
KTICRAIQRFLLAYKEERRGPTLIAVQSSWELRRLASEVPILEEFPLVPIRVADKISYGV
LDWQRHGARRMIRHYLNLDTCLSQAFEMSRYFHIPIGNLPEDISTFGSDLFFARHLQRHN
HLLWLSPTARPDLGGKEADDNRLVMEFDDRASVEINSSGCYSTVCVELDLQNLAVNTILQ
SHHVNDMEGADSMGISFDVIQQASLEDMITGGQAASAPASYDETALCSNTFRILKSMVVG
WVKEITQYHNIYADNQVMHFYRWLRSPSSLLHDPALHRTLHNMMKKLFLQLIAEFKRLGS
SVIYANFNRIILCTKKRRIEDAIAYVEYITSSIHSKDIFHSLTISFSRCWEFLLWMDPSN
YGGIKGKVSPSVHCGQQDSQEGEGAEGQQESEEEEEEEKEEEDVEEPDDVEELLENNWNI
LQFLPQAASCQSYFLMIVSAYIVAVYHSMKDGLRRSAPGSTPMKRRGASQFSQEAEGAAG
ALPGMITFSQDYVANELTQSFFTITQKIQKKVTGSRNSTELSEMFPHLPGSHLPLNNPAL
EFIKYVCKVLSLDTNITNQVNKLNRDLLRLVDVGEFSEEAQFRDPCHSYVLPEVICHSCN
FCRDLDLCKDSSFSQDGAVLPQWLCSNCQAAYDSSAIEMALVEALQRKLMAFTLQDLVCL
KCHGVKETNMPVHCGCAGDFALTIHTQVFMEQIRIFQNIAQHYGMSYLLETLEWLLQKNP
RLGQ
NT seq
6855 nt
NT seq
+upstream
nt +downstream
nt
atggctctgaggagcggcgggcgggggcgcgcggagccgggcgctgacggcgaagtgggc
cgggatgacggctcctcttcctcagtctccgcactcaagcgcctggaacggagtcagtgg
acggacaagatggatttgcggtttggctttgagcggctgaaggagcctggtgagaaaacc
ggctggctcatcaacatgcatcccactgagatcttagatgaagataaacgtttagtcagt
gcggtggattactactttattcaggacgatgggagcagatttaaggtggccctgccctat
aaaccatatttctacattgcaaccagaaagggttgtgagcgagaagtttcatcttttctt
tccaagaagtttcagggtaaaattgcaaaagtagagactgtccccaaagaggatctggac
ttgccaaatcacttagtgggtttgaagcgaaattacatcaagctatccttccacacggtg
gaggatcttgtcaaagtgaggaaggagatttcccctgctgtgaagaagaaccgggagcag
gaccatgccagcgatgcatacacagctatgctctccagtgttctgcaagggggcagtgtg
atcaccgatgaagaggaggcctctaagaagatagccgaccagctggacaacatcgtggac
atgcgcgagtacgacgtcccctaccacatccgcctctccattgacctgaagatccatgtg
gctcattggtacaacgtcagacaccgagggaatgctttgcccatggaaatcacccgccga
gatgacctcgtcgaacgacctgatcctgtggttttggcatttgacattgagacaaccaaa
ctacctctcaagtttcctgacgccgagacagaccagattatgatgatttcctacatgatc
gatggacagggctacctcatcaccaacagggagatcgtttcagaagatattgaagatttt
gagtttacccccaagccggaatatgaagggcccttttgtgtctttaatgagcccgatgag
gttcatctgatccaaaggtggtttgaacacgtccaggagaccaagcccaccatcatggtc
acctacaatggggacttttttgactggccgtttgtggaggccagggcggcagtgtacggc
ctgagcatgcaccaggagataggcttccagaaggacagccagggagagtacaaggcgccc
caatgcatccacatggactgcctcaggtgggtgaagagggacagttatcttcccgtgggc
agccacaacctcaaggcagctgccaaggccaagctgggctacgaccctgtggagctggac
cctgaggacatgtgccggatggccacggagcagccccagactctggccacgtattccgtg
tcagacgctgttgccacctactatctgtacatgaagtacgtccaccccttcatattcgct
ctgtgtaccatcatccccatggagcctgatgaggtgctccggaagggctcgggcacgctg
tgcgaggccctgctgatggtccaggccttccatgccaacatcatcttccccaacaagcag
gagcaggagctcaacaagctgacggctgacggccacgtgctggatgcagagacctacgta
gggggccacgtggaggccctcgagtctggcgtcttccgcagcgacatcccctgccggttc
cggatgaaccctgctgcctttgacttcctgctgcagcgggtggagaagaccatgcgccat
gccatcgaggaggaggagaaggtgtctgtggagcaggtcaccaactttcaagaggtgtgt
gatgagatcaagaccaagctcacctccctgaaggatgttcctaaccggattgagtgtccc
ctcatctaccacctggacgtgggagccatgtaccccaacatcatcctgacgaaccgcctg
cagccctctgccatggtagacgaggccacctgtgccgcctgcgacttcaacaagccggga
gcgaactgccagaggaagatggcctggcagtggaggggcgagttcatgccggccagtcgc
agtgaataccaccggatccagcaccagctggagtcagagaagtttccccccttgttcccg
gagggaccggctcgagcctttcatgagctgtcccgtgaggaacaggctaaatacgagaag
aagaggctggcggattactgccggaaagcctacaagaagatccacatcaccaaggtggag
gagcgcatcaccaccatctgccaacgggaaaactccttctacgtggacacggtgcgcgcc
ttccgggacagacgctatgagttcaaagggctccacaaggtgtggaagaagaagctctcg
gcggcggtggaggcaggcgatgcggccgaggtgaagcgctgcaagaacatggaggtcctg
tacgactcgctgcagctggcgcacaagtgcatcctcaactccttctacggctacgtcatg
cgcaagggggctcgctggtactccatggagatggcaggcatcgtctgcttcacgggggcc
aacatcatcacccaggcgcgcgagctgatcgagcagatcgggaggccgctagaactggac
acagatgggatatggtgcgtcctgcccaacagcttcccagaaaattttgtcctcaaaaca
accaacgcgaagaagcccagggtgaccatctcctaccctggggccatgctgaacatcctg
gtcaaggaaggcttcaccaaccaccagtaccaggagctggccgagccgtcctcactcacc
tacgtcacccgttcagaaaacagcatcttttttgaggtggatggaccctaccttgccatg
atccttccagcctccaaggaagaaggcaagaaactgaagaagagatacgctgtattcaat
gaagatggttccctggctgagctcaagggcttcgaggtcaaacgccgtggggaactgcag
ctgatcaagatcttccagtcctcggtgtttgaggcctttctcaagggcagcacgctggaa
gaggtgtatggctcggtagccaaggtggccgactactggctggacgtgttgtacagcaag
gcggctaacatgcctgattcagagctgttcgagctgatctctgagaaccgttccatgtct
cggaagctggaagattatggggagcagaagtctacgtccatcagcacggcgaagcgcctg
gctgagttcctgggagaccagatggtcaaggacgcggggctgagctgccgctacatcatc
tcccgcaagcccgagggctctcctgtcaccgagagggctatcccacttgccatcttccag
gcagagcccacagtgaggaagcactttctccggaaatggcttaagagctcttcccttcaa
gactttgatattcggacaatcctggattgggactactacatcgagaggctgggaagcgcc
atccagaagatcatcacaatccccgcagctttgcagcaggtgaagaacccagtgccacgc
gtcaaacaccctgactggctgcacagaaaactgctggagaagaatgacatctacaagcag
aagaagatcagtgagctcttcgtcctggagggcaggagacaggtcgtgatggcccaggcc
ccagagggcagtcccaggcccagcgttgctgacatggaggacttcggcctcacacagctg
ccccacccagcagtgcccgtggctacgaagaggaagcgagtcctttgggagagccaagag
gaatctcaggacctcgcactgactgtgccctggcaggagatcttggggcagccaccagcc
ctggggaccacccaggctgagtggctggtctggctcgggttccataagaagaagtggcag
ctgcaggcccggcagcgcctcgcccgcaggaagaggcagcgtctggagtcggggagcatg
ctgaggcctggggccatccgagacgggcctgccacagggctggggagctttttgcgaaaa
actgcccgcagcgttttggaccttccttggcagattgtgcagatcagcgagaccagccag
gctggcctcttccggctgtgggccgtcattggcagtgacctgcactgcatcaagctgagc
attcctcgagtgttctacgtgaaccagcgggtggccaaagcagaggacgggccttcgtat
cgcaaggtaaatcgagtccttcctcgctccaacgtggtctataatctctacgagtattca
gtgccggaagacatgtaccaggaacacatcaacgagatcaacaccgagctgtcggcaccc
gacatcgagggtgtatatgagactcaggtcccattgttgttccgggccctggtgcagctg
ggctgtgtgtgtgtcgtcaataaacagctggtcagacacctttcaggctgggaagcagac
acctttgctctcgggcacctggagatgcgttctctggcccagttcagctacctggaacca
gggagcatccgccacatctacctgtatcaccactcgcagggccacaaagcactctttggg
ctcttcatcccctcacagcgcagagcatccgtgtttgtgttggacaccgtgcgcagcaac
cagatgcccagcctcagcgccctgtactcagcagagcacagcctcctgctggacagggtg
ggccctgagctcctgccgccttccaagcacacgtttgaagttcgggctgaaactgacctg
aagaccatctgcagagctatccagcgcttccttcttgcctacaaggaggagcgccggggg
cccacactcattgctgttcagtccagctgggagctgaggaggctggccagtgaggtcccc
atcttggaggaattcccactggtgcctatccgcgtggctgacaagatcagctatggtgtc
ctggactggcaacgccatggcgcacgccgcatgatccggcactacctcaacctggacacc
tgcctgtcacaggccttcgagatgagcaggtactttcacattcccattgggaacctgcca
gaggacatctccacctttggctccgacctcttctttgcccgccacctccagcgccacaac
cacctgctatggctgtccccgacggcccgccctgacctgggtgggaaggaggccgacgat
aaccgcctggtcatggagttcgatgaccgagccagcgtggagatcaacagctcaggctgt
tactccacagtatgcgtggagctggaccttcagaacctggccgtcaacaccatcctccag
tcccaccatgtcaacgacatggagggtgccgacagcatgggcatcagcttcgacgtgatc
cagcaggcctccctggaggacatgatcacaggcggtcaggctgccagcgccccagccagc
tatgacgagacggccctctgctctaacaccttcaggatcctgaagagcatggtggtaggc
tgggtgaaggagatcacgcagtaccacaacatctacgcggacaaccaggtcatgcacttc
taccgctggcttcgctcgccatcctctctgcttcacgaccctgccctgcaccggacgctc
cataacatgatgaagaagctcttcctgcagctcatcgctgagttcaagcgcctagggtca
tcggtcatctatgccaacttcaaccgcatcatcctctgcacgaagaagcgccgaatcgaa
gatgccattgcctacgtggagtacatcaccagcagcatccattctaaggacatcttccat
tccctgacgatttctttctctcgatgctgggaatttctcctctggatggatccttctaac
tacggtggaattaaagggaaggtttcacccagtgttcactgtggacagcaagactcccag
gaaggggagggagcggagggccagcaggagagtgaggaggaggaggaagaggagaaggag
gaggaagatgtggaggaacccgacgacgtggaggagctactggagaacaactggaacatt
ctgcagtttttgccgcaggcagcctcctgccaaagctacttcctcatgattgtgtcagcg
tacatcgtggctgtgtaccacagcatgaaggacgggctgaggcgcagcgccccggggagc
acccccatgaagaggaggggtgccagccagttctcccaggaggctgagggggcggccgga
gcactcccagggatgatcaccttctctcaagactatgtagcaaacgaactcactcaaagc
ttcttcaccatcacacagaagattcaaaagaaagtcacaggctctcggaactcgaccgag
ctctccgaaatgtttcctcacctccctggttctcacctgccgctcaataaccctgctctg
gagttcatcaaatacgtgtgcaaggtgctgtccctagacacgaacatcacgaaccaggtg
aacaagctcaaccgagacctgctgcgcctggtggatgtcggcgagttctctgaggaggcc
cagttcagagacccctgccactcctacgtgctccccgaggtcatctgccacagctgcaat
ttctgcagagacctggacttgtgcaaggactcctccttctctcaggatggggccgtcttg
cctcagtggctctgctccaactgtcaggcagcctacgactcctctgccatcgagatggcc
ctggtggaagccctacagaggaagctgatggccttcaccctacaggacctggtctgcctg
aagtgccatggcgtgaaggagaccaacatgcccgtgcactgcggctgcgcaggggacttc
gccctcaccatccacactcaggtcttcatggagcagattaggatcttccagaacatcgcc
cagcactacggcatgtcgtacctcctggagaccctggagtggctgctgcagaagaaccct
cggctgggccagtag
DBGET
integrated database retrieval system
