Propithecus coquereli (Coquerel's sifaka): 105822754
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Entry
105822754 CDS
T08746
Symbol
TOP2A
Name
(RefSeq) DNA topoisomerase 2-alpha
KO
K03164
DNA topoisomerase II [EC:
5.6.2.2
]
Organism
pcoq
Propithecus coquereli (Coquerel's sifaka)
Pathway
pcoq01524
Platinum drug resistance
Brite
KEGG Orthology (KO) [BR:
pcoq00001
]
09160 Human Diseases
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
105822754 (TOP2A)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
pcoq03032
]
105822754 (TOP2A)
03036 Chromosome and associated proteins [BR:
pcoq03036
]
105822754 (TOP2A)
Enzymes [BR:
pcoq01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.2 DNA topoisomerase (ATP-hydrolysing)
105822754 (TOP2A)
DNA replication proteins [BR:
pcoq03032
]
Eukaryotic type
DNA Topoisomerases
105822754 (TOP2A)
Chromosome and associated proteins [BR:
pcoq03036
]
Eukaryotic type
Chromosome condensation proteins
Other regulators of chromosome condensation
105822754 (TOP2A)
Centrosome formation proteins
Centriole proteins
105822754 (TOP2A)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
DNA_topoisoIV
TOPRIM_C
DNA_gyraseB
DTHCT
HATPase_c
Toprim
Microp_apicomplexa_20
Motif
Other DBs
NCBI-GeneID:
105822754
NCBI-ProteinID:
XP_012515252
Ensembl:
ENSPCOG00000025407
LinkDB
All DBs
Position
Unknown
AA seq
1518 aa
AA seq
DB search
MSFTMEVSPLQPVNENMKIDKIKKNEDAKKRLSIERIYQKKTQLEHILLRPDTYIGSVEL
VTQQMWVYDEDVGINYREVTFVPGLYKIFDEILVNAADNKQRDPKMSCIRVTIDPENNLI
SIWNNGKGIPVVEHKVEKMYVPALIFGQLLTSSNYDDDEKKVTGGRNGYGAKLCNIFSTK
FTVETASREYKKMFKQTWRDNMGRAGEMELKPFNGEDYTCITFQPDLSKFKMQSLDKDIV
ALMVRRAYDIAGSTKDVKVFLNGNKLPVKGFRSYVDMYLKDKVDETGNPLKVIHEQVNHR
WEVCLTMSEKGFQQISFVNSIATSKGGRHVDYVADQIVAKLVDVVKKKNKGGVAVKAHQV
KNHMWIFVNALIENPTFDSQTKENMTLQAKSFGSTCQLSEKFIKAAIGCGIVESILNWVK
FKAQVQLNKKCSAVKHNRIKGIPKLDDANDAGGRNSTECTLILTEGDSAKTLAVSGLGVV
GRDKYGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKNYEDEDSLKTLRYGKI
MIMTDQDQDGSHIKGLLINFIHHNWPSLLRHRFLEEFITPIVKVSKNKQEMAFYSLPEFE
EWKSSTPNHKKWKVKYYKGLGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAISLAFSKK
QIDDRKEWLTHFMEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNSDNERSIP
SMVDGLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTIINLAQNFV
GSNNLNLLQPIGQFGTRLHGGKDSASPRYIFTMLSSLARLLFPPKDDHTLKFLYDDNQRV
EPEWYIPIIPMVLINGAEGIGTGWSCKIPNFDVREVVNNIRRLMDGEEPLPMLPSYKNFK
GTIEELAPNQYVISGEVAILDSTTIEISELPIRTWTQTYKEQVLEPMLNGTEKTPPLITD
YREYHTDTTVKFVVKMTEEKLAETEKAGLHKVFRLQTSLTCNSMVLFDHVGCLKKYDTVL
DILRDFFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIEGKIIIENKPKKEIIKV
LVQRGYDSDPVKAWKEAQQKVPDEEENEESDNEKETEKSDSVTDSGPTFNYLLDMPLWYL
TKEKKDELCKLRNEKEQELDTLRKKTPSDLWKEDLAAFIEELEAVEAKEKQDEQVGLPGK
GGKAKGKKTQMAEVLPSPRGKRVIPQVTIEMKAEAEKKNRKKIKSENTERSPQEDGMELE
SLKQRLEKKQKREPGTKRKKQTTLPFKPVKKGSKRNPWSDSESDMSSNDSNFDVPPRETE
PRRTTTKTKFTMDLDSDDDFSDFDEKTQDEDFVPSDASPPKTKIPPKHTTKELKPQNSGK
SEKDLDSNDKDSVPLSSSPLASDFSAETEISQSSTSTTGAKKAAPKGTRKNPALNSGVSQ
KPDPAKTKNRRKRKPSTSDDSDSNFEKIISKAATSKKSKGESDDFHLDFDSAVAPRAKSS
RAKKPIKYLEESDEDDLF
NT seq
4557 nt
NT seq
+upstream
nt +downstream
nt
atgtctttcaccatggaggtgtcaccactgcagcctgtaaatgaaaatatgaaaatcgac
aaaataaagaaaaatgaagatgctaagaaaagactgtctattgaaaggatctatcaaaag
aaaacgcaattggaacatattttgctccgcccagacacctacattggctctgtggaatta
gtgacccagcaaatgtgggtttatgatgaagatgttggcattaactatagggaagtcact
tttgttcctggtttgtacaaaatctttgatgagattctagttaatgctgcagacaacaaa
caaagggaccccaaaatgtcttgtattagagtcacaattgacccggaaaacaatttaatt
agtatatggaataatggaaaaggtattcctgttgttgaacacaaagttgagaagatgtat
gtcccagctctcatatttggacagctcctaacttctagtaactatgatgatgatgaaaag
aaagtaacaggtggtcgaaatggctatggagccaaattgtgtaacatattcagtaccaaa
tttactgtggaaacagccagtagagaatacaagaaaatgttcaaacagacatggagggat
aacatggggagagctggtgagatggaactcaagccctttaatggagaagattatacatgt
atcaccttccagcctgatttgtctaagtttaaaatgcaaagcctggacaaagatattgtt
gcactgatggttagacgagcatatgatattgctggatctaccaaagatgtcaaagtcttt
cttaatggaaataagctgccagtaaaaggatttcgtagttatgtggatatgtatttgaaa
gataaggtagatgaaactggcaacccattgaaagtaatacatgaacaagtaaaccacagg
tgggaagtgtgtttaacaatgagcgaaaaaggctttcagcaaattagctttgtcaacagc
attgctacttccaagggtggcagacatgttgattatgtagctgatcaaattgtggctaaa
cttgttgatgttgtgaagaagaagaacaagggtggtgttgcagtaaaagcacatcaggtg
aaaaatcacatgtggatttttgtgaatgctttaattgaaaacccaacctttgactctcag
acaaaagaaaacatgactttacaagccaagagctttggatcaacgtgccaattaagtgaa
aaatttatcaaagctgcaattgggtgtggtattgtagaaagcatactaaactgggtgaag
tttaaggcccaagtccagttaaacaagaagtgttcagctgtgaaacataacagaatcaag
ggaattcccaaacttgatgatgccaatgatgcaggaggccgaaactccactgagtgtaca
cttatcctgactgaaggagactcagccaaaactttggctgtttcaggccttggtgtggtt
gggagagacaaatatggggttttccctcttagaggaaaaatactcaacgttcgagaagct
tctcataaacagatcatggaaaatgctgaaataaacaatatcatcaagattgtgggtctt
cagtacaagaaaaactatgaagatgaagattcattgaaaactcttcgttatggaaagata
atgattatgacagatcaggaccaagacggttcccatatcaaaggcttgctgattaatttt
atccatcacaactggccctctcttctgagacatcgttttctggaggaatttatcactccc
attgtaaaggtgtctaaaaacaagcaagaaatggcattctatagccttcctgaatttgag
gaatggaagagttccacaccaaatcataaaaaatggaaagtcaagtattacaaaggtttg
ggcaccagcacatcaaaagaagctaaagaatactttgcagatatgaaaagacatcgtatc
cagttcaaatattctggtcctgaagatgatgctgcaatcagcctggcctttagcaaaaaa
cagatagatgatcgaaaagaatggttaactcatttcatggaggatagaagacaacgaaag
ttacttggtcttcctgaggattacttgtatgggcaaactaccacatatctgacatataat
gacttcataaacaaggaacttatcttgttctcaaattccgataatgagagatctatccca
tctatggtggatggtttgaaaccaggtcagagaaaggttttgtttacttgtttcaaacgg
aatgacaagcgagaggtgaaggttgcccagttagctgggtcagtggctgaaatgtcttct
tatcatcatggtgagatgtcactgatgatgaccattatcaatttggctcagaattttgtg
ggtagcaataatctaaacctcttgcagcctattggtcagtttggtaccaggctacatggt
ggcaaggattctgctagtcctcgatacatcttcacaatgcttagctctttggctcggttg
ttatttccaccaaaagatgatcacacattaaagttcttatatgatgacaaccaacgtgtt
gagcctgaatggtacattcctattatacccatggtcctgataaatggagccgaaggaata
ggtactgggtggtcctgcaaaatccctaactttgatgttcgtgaagttgtaaataacatc
aggcgtttgatggatggagaagaacctctgccaatgcttccaagttacaagaacttcaag
ggtactattgaagagctggctccaaatcaatatgtgattagtggtgaagtagctattctt
gattccacaaccattgaaatctcagagcttcccatcagaacatggacccagacatataag
gagcaggttctagaacccatgttgaatggcactgagaagacaccccctctcataacagac
tatagggaataccatacagacaccactgtaaaatttgtggtgaagatgactgaagaaaaa
ctggcagagacagagaaagctggactacacaaagtcttcagactccaaaccagtctcaca
tgcaactctatggtactttttgaccatgtgggctgtttaaagaaatatgacacagtgttg
gatattctaagagacttctttgaactcaggcttaaatattatggattaagaaaagaatgg
ctcttaggaatgcttggtgctgaatctgctaaactgaacaatcaggctcgctttatctta
gagaaaatagagggaaaaataatcattgaaaataagccgaagaaagaaataattaaagtt
ctggttcagaggggatatgattcagatcctgtgaaggcctggaaagaagcccaacaaaag
gttccagatgaagaagaaaatgaagagagtgacaatgaaaaggaaactgaaaagagtgac
tctgtaacagattctggaccaaccttcaactacctgcttgatatgcccctttggtatcta
accaaggaaaagaaagatgaactgtgcaaactaagaaatgaaaaagagcaagagctggac
acattaaggaaaaagactccatcagatttgtggaaagaagacttggctgcttttattgaa
gaactggaggctgttgaagccaaggaaaaacaagatgaacaagttggacttcctgggaaa
ggggggaaagcaaaggggaaaaaaactcaaatggctgaagttttgccttctccacgtgga
aaaagagtcattccccaagtaaccatagaaatgaaagcagaggcagaaaagaaaaataga
aagaaaattaagagtgaaaatactgaaagaagccctcaagaggatggtatggaactagaa
agcttaaaacaaagattagagaagaaacagaaaagagaaccaggtaccaagagaaagaaa
caaactacattgccatttaaaccagtcaaaaagggaagtaagagaaatccctggtctgat
tcagaatcagatatgagcagtaatgacagtaattttgatgtccctccacgagaaacagag
cctcggagaacaacaacaaaaaccaaattcacaatggatttggattcagatgatgatttc
tcagattttgatgaaaaaactcaagatgaagattttgtcccatcagatgctagtccacct
aaaactaaaattcccccaaaacatactaccaaagaactgaagccacagaacagtggtaag
tcagaaaaggaccttgactctaatgataaagacagtgtaccactttcttcaagccctctt
gcttctgatttctcagctgaaactgaaattagtcagtcttctacttccaccacgggtgcc
aaaaaggctgccccaaaaggaaccagaaagaatccagccttgaattctggtgtctctcaa
aagcctgatcctgcgaaaaccaaaaatcgacgcaaaaggaagccatccacttctgatgat
tccgactctaattttgagaaaattatttctaaagcagccacaagcaaaaaatccaagggg
gagagtgacgacttccatctagattttgactcagcagttgctcctcgggcaaaatccagt
cgggcaaagaaacctataaagtacctcgaagagtcagatgaagatgatctgttttaa
DBGET
integrated database retrieval system
