Propithecus coquereli (Coquerel's sifaka): 105823056
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Entry
105823056 CDS
T08746
Symbol
SDHA
Name
(RefSeq) succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial isoform X1
KO
K00234
succinate dehydrogenase (ubiquinone) flavoprotein subunit [EC:
1.3.5.1
]
Organism
pcoq
Propithecus coquereli (Coquerel's sifaka)
Pathway
pcoq00020
Citrate cycle (TCA cycle)
pcoq00190
Oxidative phosphorylation
pcoq01100
Metabolic pathways
pcoq01200
Carbon metabolism
pcoq04714
Thermogenesis
pcoq04932
Non-alcoholic fatty liver disease
pcoq05010
Alzheimer disease
pcoq05012
Parkinson disease
pcoq05014
Amyotrophic lateral sclerosis
pcoq05016
Huntington disease
pcoq05020
Prion disease
pcoq05022
Pathways of neurodegeneration - multiple diseases
pcoq05208
Chemical carcinogenesis - reactive oxygen species
pcoq05415
Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
pcoq00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
105823056 (SDHA)
09102 Energy metabolism
00190 Oxidative phosphorylation
105823056 (SDHA)
09150 Organismal Systems
09159 Environmental adaptation
04714 Thermogenesis
105823056 (SDHA)
09160 Human Diseases
09161 Cancer: overview
05208 Chemical carcinogenesis - reactive oxygen species
105823056 (SDHA)
09164 Neurodegenerative disease
05010 Alzheimer disease
105823056 (SDHA)
05012 Parkinson disease
105823056 (SDHA)
05014 Amyotrophic lateral sclerosis
105823056 (SDHA)
05016 Huntington disease
105823056 (SDHA)
05020 Prion disease
105823056 (SDHA)
05022 Pathways of neurodegeneration - multiple diseases
105823056 (SDHA)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
105823056 (SDHA)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
105823056 (SDHA)
Enzymes [BR:
pcoq01000
]
1. Oxidoreductases
1.3 Acting on the CH-CH group of donors
1.3.5 With a quinone or related compound as acceptor
1.3.5.1 succinate dehydrogenase
105823056 (SDHA)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
FAD_binding_2
Succ_DH_flav_C
Pyr_redox_2
Thi4
DAO
HI0933_like
GIDA
FAD_binding_3
Motif
Other DBs
NCBI-GeneID:
105823056
NCBI-ProteinID:
XP_012515594
Ensembl:
ENSPCOG00000025392
UniProt:
A0A2K6GIU8
LinkDB
All DBs
Position
Unknown
AA seq
665 aa
AA seq
DB search
MSGLRGLSRLLRARRLALARAQWPAAFQTRTRGFHFTVGGNKRASAKVSDSISAQYPVVD
HEFDAVVVGAGGAGLRAAFGLSEAGFNTACVTKLFPTRSHTVAAQGGINAALGNMEEDNW
RWHFYDTVKGSDWLGDQDAIHYMTEQAPAAVVELENYGMPFSRTEDGKIYQRAFGGQSLK
FGKGGQAHRCCCVADRTGHSLLHTLYGRSLRYDTSYFVEYFALDLLMESGECRGVIALCI
EDGSIHRIRARNTVVATGGYGRTYFSCTSAHTSTGDGTAMITRAGLPCQDLEFVQFHPTG
IYGAGCLITEGCRGEGGILINSQGERFMERYAPVAKDLASRDVVSRSMTLEIREGRGCGP
EKDHVYLQLHHLPPEQLAMRLPGISETAMIFAGVDVTKEPIPVLPTVHYNMGGIPTNHKG
QVLKHVDGQDQIVPGLYACGEAACASVHGANRLGANSLLDLVVFGRACALSIAESCKPGD
KVPSIKPNAGEESVMNLDKLRFADGSIRTSELRLSMQKSMQSHAAVFRVGSVLQEGCEKI
SQLYGDLKQLKTFDRGMVWNTDLVETLELQNLMLCALQTIYGAEARKESRGAHAREDYKV
RIDEYDYSKPIQGQQKKPFGEHWRKHTLSYVDVGTGKVTLEYRPVIDTTLNEADCATVPP
AIRSY
NT seq
1998 nt
NT seq
+upstream
nt +downstream
nt
atgtccgggctccgaggtttgtcgcggctgctgcgcgcgcggcgcctggcgctggcccgg
gcgcagtggccggccgcgttccagacgagaacccgagggtttcacttcactgttggtggg
aacaagagagcatctgctaaagtgtcagattctatttctgctcagtatccagtggtggat
catgaatttgatgcggtggtggtaggcgctggaggggcaggcttgcgtgctgcgtttggc
ctttccgaggcagggtttaatacagcatgtgttacgaagctctttcctaccaggtcacac
accgtcgcggcacagggcggaatcaatgctgctctgggaaacatggaagaggacaactgg
agatggcatttctatgacaccgtgaagggctccgactggctgggggaccaggatgccatc
cactacatgacagagcaggcccctgccgccgtggtcgagctagaaaattacggcatgccc
ttcagcagaactgaagatgggaagatttatcagcgtgcgtttggcggacagagcctcaag
tttggcaagggcgggcaggcccatcggtgctgctgcgtggctgatcggacggggcactcc
ctgttgcacaccttgtacggaaggtccctgcgatacgacaccagctatttcgtggagtac
tttgccttggatctcctgatggagagtggagagtgccgcggcgtcatcgcgctgtgcata
gaagacgggtccatacatcgcataagagcgaggaacactgtcgtcgctactggaggctac
gggcgcacctacttcagctgcacgtctgcccacaccagcaccggtgacggcacggccatg
atcaccagggcaggccttccctgccaggacttagagttcgttcagttccaccccacaggc
atatacggtgctggctgtctcatcacagaagggtgccgtggagagggaggcattctcatt
aacagtcagggcgagcggttcatggagcgctacgcccctgtcgcgaaggacttggcgtct
agagacgtcgtgtctcgatcaatgactctggaaatccgtgaaggaagaggctgcggccct
gagaaagatcacgtctacctgcagctgcaccacctgccccccgagcagctggccatgcgc
ctgcctggcatttcagagacagccatgatctttgctggggtggacgtcaccaaggagcca
atccccgtgctccccaccgtgcactacaacatgggcggcatccccaccaaccacaagggg
caggtcctgaagcatgtggacggccaggatcagattgtgcctggcctgtacgcctgtggg
gaggccgcctgcgcctcggtgcacggcgccaacaggctcggggccaactcgctcctggac
ctggtcgtctttggccgggcgtgtgccctgagcatcgcagagtcttgcaagcccggagat
aaagttccctcaattaaaccaaatgctggggaagaatctgtcatgaatcttgacaaattg
agatttgctgatggaagcatcagaacgtcggaattacgactcagcatgcagaagtcgatg
cagagccatgcagcggtgttccgtgtgggaagcgtgctgcaggaaggctgcgagaagatc
agtcagctctatggagacctgaagcagctgaagacgtttgacaggggaatggtctggaac
acagacctggtggagaccttggagctgcagaacctgatgctgtgtgcgctgcagaccatc
tacggagccgaggcacggaaggagtcgcggggcgcccacgccagggaggattacaaggtg
cggatcgacgagtatgactactccaagcccatccaggggcagcagaagaagccctttggg
gagcactggaggaagcacaccctttcttacgttgacgtcggcaccgggaaggtcactctg
gaatatagacctgtaatcgacacaactctgaatgaagcagactgtgccacggtccccccg
gccattcgctcctactga
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