KEGG   Propithecus coquereli (Coquerel's sifaka): 105824014
Entry
105824014         CDS       T08746                                 
Symbol
SOCS3
Name
(RefSeq) suppressor of cytokine signaling 3
  KO
K04696  suppressor of cytokine signaling 3
Organism
pcoq  Propithecus coquereli (Coquerel's sifaka)
Pathway
pcoq04120  Ubiquitin mediated proteolysis
pcoq04380  Osteoclast differentiation
pcoq04630  JAK-STAT signaling pathway
pcoq04668  TNF signaling pathway
pcoq04910  Insulin signaling pathway
pcoq04917  Prolactin signaling pathway
pcoq04920  Adipocytokine signaling pathway
pcoq04930  Type II diabetes mellitus
pcoq04931  Insulin resistance
pcoq04932  Non-alcoholic fatty liver disease
pcoq04935  Growth hormone synthesis, secretion and action
pcoq05160  Hepatitis C
pcoq05164  Influenza A
pcoq05168  Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:pcoq00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    105824014 (SOCS3)
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    105824014 (SOCS3)
   04668 TNF signaling pathway
    105824014 (SOCS3)
 09150 Organismal Systems
  09152 Endocrine system
   04910 Insulin signaling pathway
    105824014 (SOCS3)
   04920 Adipocytokine signaling pathway
    105824014 (SOCS3)
   04917 Prolactin signaling pathway
    105824014 (SOCS3)
   04935 Growth hormone synthesis, secretion and action
    105824014 (SOCS3)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    105824014 (SOCS3)
 09160 Human Diseases
  09172 Infectious disease: viral
   05160 Hepatitis C
    105824014 (SOCS3)
   05164 Influenza A
    105824014 (SOCS3)
   05168 Herpes simplex virus 1 infection
    105824014 (SOCS3)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    105824014 (SOCS3)
   04932 Non-alcoholic fatty liver disease
    105824014 (SOCS3)
   04931 Insulin resistance
    105824014 (SOCS3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:pcoq04121]
    105824014 (SOCS3)
Ubiquitin system [BR:pcoq04121]
 Ubiquitin ligases (E3)
  Multi subunit type E3
   Cul5 complex
    Target recognizing subunit
     105824014 (SOCS3)
SSDB
Motif
Pfam: SH2 SOCS_box
Other DBs
NCBI-GeneID: 105824014
NCBI-ProteinID: XP_012516803
Ensembl: ENSPCOG00000026066
UniProt: A0A2K6GLT6
LinkDB
Position
Unknown
AA seq 225 aa
MVTHSKFPAAGMSRPLDASLRLKTFSSKSEYQLVVNAVRKLQESGFYWSAVTGGEANLLL
SAEPAGTFLIRDSSDQRHFFTLSVKTQSGTKNLRIQCEGGSFSLQSDPRSTQPVPRFDCV
LKLVHHYMPPPGAPSFPSPPTEPSSEVPEQPPAQPLPGSPPRRAYYIYSGGEKIPLVLSR
PLSSNVATLQHLCRKTVNGHLDSYQKVTQLPGPIREFLDQYDAPL
NT seq 678 nt   +upstreamnt  +downstreamnt
atggtcacccacagcaagtttcccgccgccgggatgagccgccccctggacgccagcctg
cgcctcaagaccttcagctccaagagcgagtaccagctggtggtgaacgcagtgcgcaag
ctgcaggagagcggtttctactggagcgccgtaaccggcggcgaggcgaacctgctgctc
agcgcagagcccgccggcaccttcctcatccgcgacagctccgaccagcgccacttcttc
acgctcagcgtcaagacccagtcggggaccaagaacctgcgcatccagtgcgaggggggc
agcttctctctgcagagcgacccccggagcacgcagcccgtgccccgcttcgactgcgtg
ctcaagctggtgcaccactacatgccacctcccggcgccccctccttcccctcgccaccg
acggaaccctcctccgaggtgcccgagcagccgcccgcccagccgctcccagggagcccc
cccaggagagcctattacatctactcagggggcgagaagattcccctggtgctgagccgg
cccctctcctccaacgtggccactctgcagcatctctgtcggaagaccgtcaacggccac
ctggactcctatcagaaagttacccagctgcctgggcccattcgggagttcctggaccag
tacgatgccccgctctaa

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