KEGG   Propithecus coquereli (Coquerel's sifaka): 105825283
Entry
105825283         CDS       T08746                                 
Symbol
PPP3CC
Name
(RefSeq) serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform
  KO
K04348  serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
Organism
pcoq  Propithecus coquereli (Coquerel's sifaka)
Pathway
pcoq04010  MAPK signaling pathway
pcoq04020  Calcium signaling pathway
pcoq04022  cGMP-PKG signaling pathway
pcoq04114  Oocyte meiosis
pcoq04218  Cellular senescence
pcoq04310  Wnt signaling pathway
pcoq04360  Axon guidance
pcoq04370  VEGF signaling pathway
pcoq04380  Osteoclast differentiation
pcoq04625  C-type lectin receptor signaling pathway
pcoq04650  Natural killer cell mediated cytotoxicity
pcoq04658  Th1 and Th2 cell differentiation
pcoq04659  Th17 cell differentiation
pcoq04660  T cell receptor signaling pathway
pcoq04662  B cell receptor signaling pathway
pcoq04720  Long-term potentiation
pcoq04724  Glutamatergic synapse
pcoq04728  Dopaminergic synapse
pcoq04921  Oxytocin signaling pathway
pcoq04922  Glucagon signaling pathway
pcoq04924  Renin secretion
pcoq05010  Alzheimer disease
pcoq05014  Amyotrophic lateral sclerosis
pcoq05020  Prion disease
pcoq05022  Pathways of neurodegeneration - multiple diseases
pcoq05031  Amphetamine addiction
pcoq05152  Tuberculosis
pcoq05163  Human cytomegalovirus infection
pcoq05166  Human T-cell leukemia virus 1 infection
pcoq05167  Kaposi sarcoma-associated herpesvirus infection
pcoq05170  Human immunodeficiency virus 1 infection
pcoq05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
pcoq05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pcoq00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    105825283 (PPP3CC)
   04310 Wnt signaling pathway
    105825283 (PPP3CC)
   04370 VEGF signaling pathway
    105825283 (PPP3CC)
   04020 Calcium signaling pathway
    105825283 (PPP3CC)
   04022 cGMP-PKG signaling pathway
    105825283 (PPP3CC)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    105825283 (PPP3CC)
   04218 Cellular senescence
    105825283 (PPP3CC)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    105825283 (PPP3CC)
   04650 Natural killer cell mediated cytotoxicity
    105825283 (PPP3CC)
   04660 T cell receptor signaling pathway
    105825283 (PPP3CC)
   04658 Th1 and Th2 cell differentiation
    105825283 (PPP3CC)
   04659 Th17 cell differentiation
    105825283 (PPP3CC)
   04662 B cell receptor signaling pathway
    105825283 (PPP3CC)
  09152 Endocrine system
   04922 Glucagon signaling pathway
    105825283 (PPP3CC)
   04921 Oxytocin signaling pathway
    105825283 (PPP3CC)
   04924 Renin secretion
    105825283 (PPP3CC)
  09156 Nervous system
   04724 Glutamatergic synapse
    105825283 (PPP3CC)
   04728 Dopaminergic synapse
    105825283 (PPP3CC)
   04720 Long-term potentiation
    105825283 (PPP3CC)
  09158 Development and regeneration
   04360 Axon guidance
    105825283 (PPP3CC)
   04380 Osteoclast differentiation
    105825283 (PPP3CC)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    105825283 (PPP3CC)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    105825283 (PPP3CC)
   05170 Human immunodeficiency virus 1 infection
    105825283 (PPP3CC)
   05163 Human cytomegalovirus infection
    105825283 (PPP3CC)
   05167 Kaposi sarcoma-associated herpesvirus infection
    105825283 (PPP3CC)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    105825283 (PPP3CC)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    105825283 (PPP3CC)
   05014 Amyotrophic lateral sclerosis
    105825283 (PPP3CC)
   05020 Prion disease
    105825283 (PPP3CC)
   05022 Pathways of neurodegeneration - multiple diseases
    105825283 (PPP3CC)
  09165 Substance dependence
   05031 Amphetamine addiction
    105825283 (PPP3CC)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    105825283 (PPP3CC)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:pcoq01009]
    105825283 (PPP3CC)
Enzymes [BR:pcoq01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     105825283 (PPP3CC)
Protein phosphatases and associated proteins [BR:pcoq01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Calcineurin (PPP3/ PP2B)
    Catalytic subunits
     105825283 (PPP3CC)
SSDB
Motif
Pfam: Metallophos DUF5378
Other DBs
NCBI-GeneID: 105825283
NCBI-ProteinID: XP_012518494
Ensembl: ENSPCOG00000018145
UniProt: A0A2K6FGG3
LinkDB
Position
Unknown
AA seq 511 aa
MSEGRSQLSTTERVIKAVPFPPTQRLTLKEVFENGKPKIDVLKNHLVKEGRLEEEVALKI
IKDGAAILRQEKTMIEVEAPITVCGDIHGQFFDLMKLFEVGGSPSNTRYLFLGDYVDRGY
FSIECVLYLWSLKINHPKTLFLLRGNHECRHLTDYFTFKQECRIKYSEQVYDACMDTFDC
LPLAALLNQQFLCVHGGMSPEITCLDDIRRLDRFIEPPAFGPVCDLLWSDPSEDYGNEKT
LEHYTHNTVRGCSYFYSYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLIT
IFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEM
LVNILNICSDDELIDDDEAEGGTTVRKEIIKNKIRAIGKMARVFSVLREESESVLTLKGL
TPTGTLPLGVLSGGKQTIETATVEAVEAREAIRGFSLQHKIRSFEEARGLDRINERMPPR
KDGVRSDGPVKSVSPAHPKSQHRSNHGKKAQ
NT seq 1536 nt   +upstreamnt  +downstreamnt
atgtccgaggggcgctcccaactctccactaccgaacgcgtcatcaaagctgttcccttt
cctccaacccaacggcttactttgaaggaagtatttgagaatgggaaacctaaaattgat
gtcttgaaaaatcatttggtaaaggagggccgactagaagaggaagtggccttaaaaata
atcaaggatggggctgccatcctgagacaagagaagaccatgatagaagtagaggctcca
atcacagtgtgtggtgacattcatggacaattctttgacctgatgaagttatttgaggtt
ggaggatcacctagtaacacacgctacctctttctgggtgactatgtggacagaggctat
ttcagtatagagtgtgtgctgtatttatggagtttaaagattaatcatcccaaaacattg
tttctgcttcgaggaaatcatgaatgccggcatcttacagactatttcaccttcaaacaa
gaatgtcgcatcaaatattctgaacaggtgtatgatgcgtgtatggatacatttgactgt
cttcctcttgctgccctcttaaaccagcagtttctctgtgtacatggaggaatgtcacct
gaaattacttgtttagatgacattaggagattagacaggtttattgaacctcctgccttc
gggccagtgtgtgacctgctttggtctgatccctccgaggattatggcaatgaaaagacc
ctggagcactacacccacaacactgtccgagggtgctcttatttttacagttaccctgca
gtttgtgaatttttgcagaacaataatttattatcaattatcagagcccatgaagcccaa
gatgccgggtatcgaatgtacaggaagagccaaacaacaggctttccatcacttattaca
attttctctgcccctaattacctagatgtctataacaataaagctgctgtgttgaaatat
gaaaataatgtcatgaacatcaggcagtttaactgttctccacacccctactggcttcca
aactttatggatgttttcacatggtctttaccttttgttggggaaaaagtcacagagatg
ctggttaacattctcaacatatgctctgatgatgaactgattgatgatgatgaagcagaa
ggaggcactacagttcgtaaggagatcatcaagaataagatcagagccattgggaagatg
gcacgggtcttttcagttcttcgggaggagagtgagagtgtgctgactctcaagggcctg
acgcctacaggtacactccctctgggcgtcctctcaggagggaagcagactattgagact
gccacagtagaagcggtagaggcccgggaagccatcagaggattttcgcttcagcacaag
atccggagttttgaagaagcccgaggtctggaccgaattaatgagcgaatgccaccccga
aaagatggtgtacgctctgatgggccagtgaaatctgtaagcccagcacacccaaagtct
cagcacaggagcaaccacgggaagaaagcccagtaa

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