KEGG   Pseudorca crassidens (false killer whale): 137221872
Entry
137221872         CDS       T12027                                 
Symbol
CSF1R
Name
(RefSeq) macrophage colony-stimulating factor 1 receptor
  KO
K05090  macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1]
Organism
pcrs  Pseudorca crassidens (false killer whale)
Pathway
pcrs04010  MAPK signaling pathway
pcrs04014  Ras signaling pathway
pcrs04015  Rap1 signaling pathway
pcrs04060  Cytokine-cytokine receptor interaction
pcrs04061  Viral protein interaction with cytokine and cytokine receptor
pcrs04151  PI3K-Akt signaling pathway
pcrs04380  Osteoclast differentiation
pcrs04640  Hematopoietic cell lineage
pcrs05200  Pathways in cancer
pcrs05202  Transcriptional misregulation in cancer
pcrs05221  Acute myeloid leukemia
Brite
KEGG Orthology (KO) [BR:pcrs00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    137221872 (CSF1R)
   04014 Ras signaling pathway
    137221872 (CSF1R)
   04015 Rap1 signaling pathway
    137221872 (CSF1R)
   04151 PI3K-Akt signaling pathway
    137221872 (CSF1R)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    137221872 (CSF1R)
   04061 Viral protein interaction with cytokine and cytokine receptor
    137221872 (CSF1R)
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    137221872 (CSF1R)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    137221872 (CSF1R)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    137221872 (CSF1R)
   05202 Transcriptional misregulation in cancer
    137221872 (CSF1R)
  09162 Cancer: specific types
   05221 Acute myeloid leukemia
    137221872 (CSF1R)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:pcrs01001]
    137221872 (CSF1R)
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:pcrs04090]
    137221872 (CSF1R)
Enzymes [BR:pcrs01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     137221872 (CSF1R)
Protein kinases [BR:pcrs01001]
 Receptor tyrosine kinases (RTK)
  PDGFR family [OT]
   137221872 (CSF1R)
CD molecules [BR:pcrs04090]
 Proteins
  137221872 (CSF1R)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase Ig_3 I-set ig Ig_2 VEGFR1-3_N_Ig-like Ig_VEGFR-1-like_5th Ig_PDGFR_d4 V-set V-set_CD47 VEGFR-1-like_Ig-like
Other DBs
NCBI-GeneID: 137221872
NCBI-ProteinID: XP_067588350
LinkDB
Position
3:complement(126183005..126213324)
AA seq 961 aa
MGPGTLLILLVATAWHGQGVPVIEPSGPELVVEPGTAVTLRCVSNGSVEWDGPISTYWTL
DADAPSSILTTNNATFLNTGTYRCTERGDPLGGSATIHLYVKDPVRPWRVLVEEVTVMEG
QDALLPCLLTDPALGAGVSLVRVRGRPVLRQTNYSFLPSHGFIIHKAKFIESQDYECSAR
VDGRMVKSLSIRLKVQKVIPGPPTLTLKPTELVRIRGEAAQIVCSASDVDVNFDVFLQHG
DTKLTISQQSDFHDNRYQKVLTLNLDHVSFQDAGNYTCTATNARGIHSTSMVFWVVDSAY
LNLTSEQNLLQEVTVGEKIELKVKVEAYPSLQSFNWTYQGPFLGHQPKLNFVTNKGTYRY
TSTLTLLRLKPFEAGHYSFQARNARGEETLTFELTLLYPPEVEVTWTLINGSKTLLCEAS
GYPQPNVTWVQCRGHTNRCDKTQVLVLDDPNPEVLSQKPFHKVTVQSLLATGTLEHNRTY
ECRAYNSLGNSSQAFGPVSVGAYTQPLDEPLFTPVLAACMSVMALLLLLLLLLLYKYKQK
PKYQVRWKIIESYGGNSYTFIDPTQLPYNEKWEFPRNNLQFGKTLGAGAFGKVVEATAFG
LGKEDAVLKVAVKMLKSTAHADEKEALMSELKIMSHLGQHENIVNLLGACTHGGPVLVIT
EYCCYGDLLNFLRRKAEAMLGPSLNPGQDPKAGTGYKNIHLEKKYIRRDSGFSSQGVDTY
VEMRPVSTSSSNDSFSEQDLDKENGRLLELRDLLHFSSQVAQGMAFLASKNCIHRDVAAR
NVLLTSGHVAKIGDFGLARDIMNDSNYIVKGNARLPVKWMAPESIFDCVYTVQSDVWSYG
ILLWEIFSLGLNPYPGILVNSKFYKLVKDGYQMAQPAFAPKNIYSIMQACWALEPTRRPT
FQQICSLLQEQVLVDRREQDYSNLPSSSSEPEEESSSEHLGCCEQGDVAQPLLQPNNYQF
C
NT seq 2886 nt   +upstreamnt  +downstreamnt
atgggcccaggtactctgctgatcctgttggtggccacagcttggcacggtcagggggtc
ccggtgatagagcccagtggtcctgagctggtcgtggagccaggcacagccgtgaccttg
agatgtgtgagcaacggcagcgtggaatgggacggccccatttccacctactggactctg
gacgctgacgcccccagcagcatcctcaccacgaacaatgccaccttcctaaacacggga
acctaccgctgcactgagcgtggagaccccctggggggcagcgccaccatccatctctat
gtcaaagaccctgttcggccctggagggtcctggtcgaggaagtgacggtgatggagggt
caggacgcgctgctgccctgcctgctcacggacccagcgctgggggcaggcgtctcgctg
gtgcgggtgcgtggccgacctgtcttgcgccaaaccaactactccttcttgccctcgcac
ggcttcatcatccacaaggccaagttcatcgaaagccaggactatgagtgcagtgctcgg
gtggacggcaggatggtgaagtccctcagcatccggcttaaagttcagaaagtcatccca
ggacccccgaccttgaccctgaagcctacagagctggtgcggattcgaggagaggctgcc
cagatcgtatgctcagccagtgacgttgatgtcaactttgatgtcttcctccaacacgga
gacaccaagctcacaatctctcaacaatccgacttccatgacaaccgttatcaaaaagtc
ctgacgctcaacctcgatcacgtaagcttccaagatgctggcaactacacctgcacggcc
accaatgcccggggcatccactccacctccatggtcttctgggtggtagacagtgcctac
ttgaacttgacctctgagcagaacctcctccaggaggtgaccgtgggtgagaagatcgaa
ctcaaagtcaaggtggaggcctacccaagcctgcaaagttttaactggacctatcaggga
cccttccttggccaccagcccaagctcaattttgtaaccaacaagggcacatacaggtac
acctccaccctcaccctgcttcgcctgaagcccttcgaggccggccactactccttccag
gccagaaatgccagaggcgaggagaccctgacctttgaactcacccttctatacccccca
gaggtagaggtcacgtggaccctcatcaacggctctaaaaccctgctctgtgaagcctca
gggtacccccagcccaatgtgacgtgggtgcagtgcaggggccacacgaacagatgtgat
aagacccaagtgctggtcctggacgacccgaaccctgaggtcctgagccaaaagcccttc
cacaaggtgaccgtccagagcctgctggccactgggaccttggaacacaacaggacgtac
gagtgcagggcctacaacagcctggggaacagctcccaggccttcgggcctgtctctgta
ggagcctacacgcagccccttgacgagcccctcttcacgccggtgctggcggcctgcatg
tccgtcatggccttgctgctgctgctactcctgttgcttttgtacaagtacaagcagaag
cccaagtaccaggtgcgctggaagatcattgagagctacgggggcaacagctacaccttc
atcgatccaacccagctgccctacaacgagaagtgggagttcccccggaacaacctgcag
tttggtaaaacccttggagcaggtgcctttgggaaggtggtagaggccacggcctttggt
ctgggcaaggaagatgctgttctgaaggtggctgtgaagatgctgaagtccacggctcac
gctgacgagaaggaggccctcatgtcggaactgaagatcatgagccacctgggccagcac
gagaacatagtcaaccttctgggagcctgtacccacggaggccctgtcctggtcatcacc
gagtactgctgctatggcgacctgctcaactttctgcgaaggaaggctgaggccatgctg
ggacccagcctgaatccaggccaggaccccaaggcaggcaccggctacaagaacatccac
ttggaaaagaaatacatccgcagggacagcggcttctccagccagggtgtggacacctat
gtggagatgaggcctgtctccacttcttcatcaaatgattcattctctgagcaagacctg
gacaaggagaacgggcggctgctggagctgcgtgacctgctccacttttccagccaggtg
gcccagggcatggcattcctcgcttccaagaactgcatccaccgggacgtggcagccaga
aacgtgctgctgaccagtggccatgtggccaagattggggactttggtctggctagggac
atcatgaatgactccaactacatcgtcaagggcaacgcccgcctgcccgtgaagtggatg
gccccagagagcatcttcgactgcgtctacacagttcagagcgacgtctggtcctacggc
atcctcctctgggagatcttctcacttggcctgaacccctaccctggcatcctggtgaac
agcaagttctataaactggtgaaggacggataccaaatggcccagcctgcgtttgcccca
aagaacatatacagcatcatgcaggcctgctgggccctggagccgacccgcagacccacc
ttccagcaaatctgctccctccttcaggagcaggttctagtggatagaagagagcaggac
tacagcaacctaccaagcagcagcagtgagccggaggaggagagctccagcgagcacctg
ggctgctgtgagcagggggacgttgcccagcccctgctgcaacccaacaactaccagttc
tgctga

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