Pseudorca crassidens (false killer whale): 137227447
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Entry
137227447 CDS
T12027
Symbol
HSPA5
Name
(RefSeq) endoplasmic reticulum chaperone BiP
KO
K09490
endoplasmic reticulum chaperone BiP [EC:
5.6.1.10
]
Organism
pcrs
Pseudorca crassidens (false killer whale)
Pathway
pcrs03060
Protein export
pcrs04141
Protein processing in endoplasmic reticulum
pcrs04156
Integrated stress response (ISR) signaling pathway
pcrs04612
Antigen processing and presentation
pcrs04918
Thyroid hormone synthesis
pcrs05012
Parkinson disease
pcrs05014
Amyotrophic lateral sclerosis
pcrs05020
Prion disease
pcrs05022
Pathways of neurodegeneration - multiple diseases
pcrs05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
pcrs00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
03060 Protein export
137227447 (HSPA5)
04141 Protein processing in endoplasmic reticulum
137227447 (HSPA5)
09140 Cellular Processes
09143 Cell growth and death
04156 Integrated stress response (ISR) signaling pathway
137227447 (HSPA5)
09150 Organismal Systems
09151 Immune system
04612 Antigen processing and presentation
137227447 (HSPA5)
09152 Endocrine system
04918 Thyroid hormone synthesis
137227447 (HSPA5)
09160 Human Diseases
09164 Neurodegenerative disease
05012 Parkinson disease
137227447 (HSPA5)
05014 Amyotrophic lateral sclerosis
137227447 (HSPA5)
05020 Prion disease
137227447 (HSPA5)
05022 Pathways of neurodegeneration - multiple diseases
137227447 (HSPA5)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
137227447 (HSPA5)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03110 Chaperones and folding catalysts [BR:
pcrs03110
]
137227447 (HSPA5)
04131 Membrane trafficking [BR:
pcrs04131
]
137227447 (HSPA5)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
pcrs04147
]
137227447 (HSPA5)
Enzymes [BR:
pcrs01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.1 Enzymes altering polypeptide conformation or assembly
5.6.1.10 non-chaperonin molecular chaperone ATPase
137227447 (HSPA5)
Chaperones and folding catalysts [BR:
pcrs03110
]
Heat shock proteins
HSP70 / DNAK
137227447 (HSPA5)
Membrane trafficking [BR:
pcrs04131
]
Endoplasmic reticulum (ER) - Golgi transport
Forward pathways
ER-Golgi intermediate compartment (ERGIC) proteins
137227447 (HSPA5)
Autophagy
ER-phagy
ER stress-related proteins
137227447 (HSPA5)
Exosome [BR:
pcrs04147
]
Exosomal proteins
Exosomal proteins of haemopoietic cells (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
137227447 (HSPA5)
Exosomal proteins of other body fluids (saliva and urine)
137227447 (HSPA5)
Exosomal proteins of colorectal cancer cells
137227447 (HSPA5)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
HSP70
MreB_Mbl
FtsA
Hydantoinase_A
FGGY_C
DDR
Motif
Other DBs
NCBI-GeneID:
137227447
NCBI-ProteinID:
XP_067599420
LinkDB
All DBs
Position
7:10393490..10398459
Genome browser
AA seq
655 aa
AA seq
DB search
MKPSLVAAVLLLMLGAARPEEEDKKEDVGTVVGIDLGTTYSCVGVFKNGRVEIIANDQGN
RITPSYVAFTPEGERLIGDAAKNQLTSNPENTVFDAKRLIGRTWNDPSVQQDIKFLPFKV
VEKKTKPYIQVDVGGGQTKTFAPEEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDA
QRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKREGEKNILVFDLGGGTFDVSLLTIDN
GVFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRAL
SSQHQARIEIESFYEGEDFSETLTRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEI
VLVGGSTRIPKIQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLLDV
CPLTLGIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLL
GTFDLTGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIE
RMVNDAEKFAEEDKKLKERIDTRNELESYAYSLKNQIGDKEKLGGKLSSEDKETMEKAVE
EKIEWLESHQDADIEDFKAKKKELEEIVQPIISKLYGSAGPPPTGDEEPADKDEL
NT seq
1968 nt
NT seq
+upstream
nt +downstream
nt
atgaagccctccctggtggctgcggtgctgctgctgatgctcggcgcggcgcggccggag
gaggaggacaagaaggaggacgtgggcacggtggtcggtatcgacctgggcaccacgtac
tcctgcgtcggggtgttcaaaaacggccgcgtggagatcatcgccaacgatcagggcaac
cgcatcacgccgtcttatgtggccttcactcctgaaggggagcgtctgatcggcgatgca
gccaagaaccagctcacctccaatcctgagaacacggtcttcgacgccaagcggctcatc
ggccgtacatggaacgacccgtctgtgcagcaggacatcaagttcttgcctttcaaggtg
gttgaaaagaaaactaaaccgtacattcaagttgatgttggaggtgggcaaacaaagaca
tttgctcctgaagaaatttctgccatggttctcactaaaatgaaggaaactgccgaggct
tatttgggaaagaaggttactcatgcagttgttactgtaccagcctatttcaatgatgcc
caacgccaggcaaccaaagatgctggaactattgctgggttgaatgttatgaggatcatc
aatgagcctacagcagctgctattgcttacggcctggataagagggaaggggagaagaac
atcctggtgtttgacttgggtggtggaacctttgatgtgtctcttctcaccattgataat
ggtgtctttgaagttgtggccactaatggagatactcatttgggtggagaagactttgac
cagcgtgtcatggaacacttcatcaagctgtacaaaaagaaaactggcaaagatgttcgg
aaagacaacagagctgtgcagaaactccggcgtgaggttgaaaaggccaaacgggccctg
tcttctcaacatcaagcaagaattgaaattgagtccttctatgaaggagaagacttctct
gagacccttactcgggccaaatttgaagagctaaacatggatctgttccgttctaccatg
aagcctgtccagaaagtgctggaagattctgatttaaagaagtctgatattgatgaaatt
gttcttgttggtggctctactagaatcccaaagattcaacaactggttaaagagtttttc
aatggcaaggagccatcccgtggcataaacccagatgaggctgtagcgtatggtgctgct
gtccaggctggtgtactctctggtgatcaagatacaggtgatctggtattgcttgatgta
tgtccccttacacttggtattgaaaccgtgggaggtgtcatgaccaaactgattccaagg
aacactgtggtgcccaccaagaagtctcagatcttttctacagcctctgataatcagcca
actgttaccatcaaggtctatgaaggtgaacgacccctgacgaaagacaatcaccttctg
ggaacttttgatctgactggaattcctcctgctccccgtggggttccacagattgaagtc
acctttgagatagatgtgaatggcattcttcgagtgacagctgaagacaaaggtacaggc
aacaaaaataaaatcacaattacaaatgaccaaaatcgcctgacacctgaagaaattgaa
aggatggtcaatgatgctgagaagttcgctgaggaagacaaaaagctcaaggagcgcatt
gacaccagaaatgagttggaaagctatgcctactctctaaagaatcagattggagataaa
gaaaagctgggaggtaaactttcctctgaagataaggagaccatggaaaaagctgtagaa
gaaaagattgagtggctagaaagtcaccaagatgctgacattgaagatttcaaagctaaa
aagaaggagctggaagaaattgttcagccaattatcagcaaactctatggaagtgcaggc
cctcccccaactggtgatgaggaaccagcagacaaagacgagttgtag
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