Phascolarctos cinereus (koala): 110192705
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Entry
110192705 CDS
T05867
Symbol
IGF1R
Name
(RefSeq) insulin-like growth factor 1 receptor
KO
K05087
insulin-like growth factor 1 receptor [EC:
2.7.10.1
]
Organism
pcw
Phascolarctos cinereus (koala)
Pathway
pcw01521
EGFR tyrosine kinase inhibitor resistance
pcw01522
Endocrine resistance
pcw04010
MAPK signaling pathway
pcw04014
Ras signaling pathway
pcw04015
Rap1 signaling pathway
pcw04066
HIF-1 signaling pathway
pcw04068
FoxO signaling pathway
pcw04081
Hormone signaling
pcw04114
Oocyte meiosis
pcw04140
Autophagy - animal
pcw04144
Endocytosis
pcw04150
mTOR signaling pathway
pcw04151
PI3K-Akt signaling pathway
pcw04152
AMPK signaling pathway
pcw04211
Longevity regulating pathway
pcw04213
Longevity regulating pathway - multiple species
pcw04510
Focal adhesion
pcw04520
Adherens junction
pcw04550
Signaling pathways regulating pluripotency of stem cells
pcw04730
Long-term depression
pcw04913
Ovarian steroidogenesis
pcw04914
Progesterone-mediated oocyte maturation
pcw05200
Pathways in cancer
pcw05202
Transcriptional misregulation in cancer
pcw05205
Proteoglycans in cancer
pcw05214
Glioma
pcw05215
Prostate cancer
pcw05218
Melanoma
pcw05224
Breast cancer
pcw05225
Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:
pcw00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
110192705 (IGF1R)
04014 Ras signaling pathway
110192705 (IGF1R)
04015 Rap1 signaling pathway
110192705 (IGF1R)
04066 HIF-1 signaling pathway
110192705 (IGF1R)
04068 FoxO signaling pathway
110192705 (IGF1R)
04151 PI3K-Akt signaling pathway
110192705 (IGF1R)
04152 AMPK signaling pathway
110192705 (IGF1R)
04150 mTOR signaling pathway
110192705 (IGF1R)
09133 Signaling molecules and interaction
04081 Hormone signaling
110192705 (IGF1R)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
110192705 (IGF1R)
04140 Autophagy - animal
110192705 (IGF1R)
09143 Cell growth and death
04114 Oocyte meiosis
110192705 (IGF1R)
09144 Cellular community - eukaryotes
04510 Focal adhesion
110192705 (IGF1R)
04520 Adherens junction
110192705 (IGF1R)
04550 Signaling pathways regulating pluripotency of stem cells
110192705 (IGF1R)
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
110192705 (IGF1R)
04914 Progesterone-mediated oocyte maturation
110192705 (IGF1R)
09156 Nervous system
04730 Long-term depression
110192705 (IGF1R)
09149 Aging
04211 Longevity regulating pathway
110192705 (IGF1R)
04213 Longevity regulating pathway - multiple species
110192705 (IGF1R)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
110192705 (IGF1R)
05202 Transcriptional misregulation in cancer
110192705 (IGF1R)
05205 Proteoglycans in cancer
110192705 (IGF1R)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
110192705 (IGF1R)
05214 Glioma
110192705 (IGF1R)
05218 Melanoma
110192705 (IGF1R)
05215 Prostate cancer
110192705 (IGF1R)
05224 Breast cancer
110192705 (IGF1R)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
110192705 (IGF1R)
01522 Endocrine resistance
110192705 (IGF1R)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pcw01001
]
110192705 (IGF1R)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
pcw04090
]
110192705 (IGF1R)
Enzymes [BR:
pcw01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
110192705 (IGF1R)
Protein kinases [BR:
pcw01001
]
Receptor tyrosine kinases (RTK)
INSR family [OT]
110192705 (IGF1R)
CD molecules [BR:
pcw04090
]
Proteins
110192705 (IGF1R)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
Furin-like
Pkinase
fn3
Kinase-like
Motif
Other DBs
NCBI-GeneID:
110192705
NCBI-ProteinID:
XP_020819709
UniProt:
A0A6P5IM15
LinkDB
All DBs
Position
Unknown
AA seq
1366 aa
AA seq
DB search
MKSGAGRGSPTSLWGLLFLFSTLCLWPTNGEICGPNIDIRNEIQELKRLENCTVIEGYLR
ILLISKAEDYRNFRFPKLTVITDYLLLFRVAGLESLSDLFPNLTVIRGRNLFYNYALVIF
EMTNLKEIGLYNLRNITRGAIRIEKNSDLCYLSTVDWSLILDAVSNNYIVGNKSPKECGD
LCPGTMEEKPLCEKTTINNEYNYRCWTTNHCQKMCPSSCGKRACTDQNQCCHPECLGSCS
APDNDTACVACRHYYYGGTCVPTCPPNTYKFEGWRCVDRDFCASVHSAEANEYEKFVIHN
DECMQECPSGFIRNGSQSMYCSPCEGPCPKVCEGEKKTKTIDSVTSAQMLQGCTVFKGNL
LINIRRGAVNNIASELENFMGLIETVTGYVKIRHSHALVSLSFLKNLRNILGEEQLEGNY
SFYVLDNQNLQQLWDWNLHNLTIKEGKMYFAFNPKLCVSEIYRMEEVSGTKGRQSKGDIN
TRNNGERASCESDVLHFISNTTMKNRIKLTWQRYRPPDYRDLISFTVYFKEAPFKNVTEY
DGQDACGSNSWNMVDVDLPPNKDVKPGILLQGLKPWTQYAIYVKAVTLTMVENDHIRGAK
SEIVYIRTKAAVPSIPLDVISASNSSSQLIVKWNPPSLPNGNLSYYIVRWQRQPQDSYLY
RHNYCSKDKVPIRKYADGTIDVEEVTENPKTEVCGGEKGPCCACPKTEAEKQAEKEEAEY
RKVFENFLHNSIFVPRPERRRRDVFQIANSTLPSRNRNTTMADHFTNMSDTEEIESEYPF
FESRVDNKERTLISHLRPFTLYRIDIHSCNHEADTLGCSASNFVFARTMPAEGADNIPGP
VLWEPRPDNTVYLKWSEPENPNGLILMYEIKYGQQVEDQRECVSRQEYRKFGGARLTRLN
PGNYSARVQATSLSGNGSWTDPVFFYVPAKPPDYENFIHLMIALPIAGLFILGGILIMWY
VYNKKRNSDRLGNGVLYASVNPEYFSAADVYVPDEWEVPREKITMSRELGQGSFGMVYEG
VAKGVVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTL
VIMELMTRGDLKSYLRSLRPETENNPCQMLPTLKKMIQMAGEIADGMAYLNANKFVHRDL
AARNCMVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTHSDVW
SFGVVLWEIATLAEQPYQGMSNEQVLRFVMEGGLLEKPDNCPDMLFELMRMCWQYNPKMR
PSFLEIIGSIKDELDPSFKEVSFFYSEENKPPDTEELDLETENMESIPLDPSSTLQPADK
LSGHKAENGPGVVVLRASFDERQPYAHMNGGRKNERALPLPQSSAC
NT seq
4101 nt
NT seq
+upstream
nt +downstream
nt
atgaagtctggcgccggaagagggtccccgacctcactttgggggcttctgtttctcttt
tctacactttgcctttggccaacaaatggagaaatttgtgggccaaacattgacattcgc
aatgaaatccaggagttgaagcgactagaaaactgcacagtgattgagggctacctccga
attctactgatctctaaggcagaggactacaggaacttccgattcccaaagctcacggtc
atcactgactacttgctgctttttcgtgtggcgggcttggagagccttagtgacctcttc
cctaaccttacggtcattcgagggagaaaccttttttataactatgccctggtgatcttt
gagatgacaaatctcaaagagatcgggctatataaccttaggaatatcactcggggggcc
atcaggattgagaagaattcagacctctgttacctctccactgtggactggtctttgatt
ctggatgctgtatctaacaactatattgtgggaaataaatctccaaaggaatgtggggac
ctttgtccaggaacaatggaagagaagccattgtgtgaaaagacaaccattaataatgag
tacaactaccgctgctggaccacaaaccactgtcagaaaatgtgtcctagctcatgtgga
aagcgggcctgcacagaccagaatcaatgttgccacccagagtgcttaggaagctgtagt
gcaccagacaatgacacagcctgtgtggcttgccgccattattactatgggggcacttgt
gtgcctacctgtcctcctaacacttacaagtttgagggttggcgttgcgttgacagagat
ttttgtgccagcgtccacagtgccgaagccaacgaatatgaaaagtttgtgatccacaat
gatgagtgcatgcaagagtgtccctctgggttcatacggaatgggagccaaagtatgtac
tgcagcccctgtgaaggtccttgccctaaagtctgtgagggagagaagaagacgaagaca
attgattctgtaacttcagcacaaatgctgcagggatgcactgtcttcaaaggcaatttg
cttattaatatccggcgaggggcagtaaataacatagcttctgagctggaaaacttcatg
ggccttattgagactgtaacaggatatgtgaagattcgccattcacatgccttggtgtct
ctgtctttcttgaaaaacctgcgaaatattttaggagaagaacagctagaagggaattat
tctttctacgtccttgataaccagaatttgcagcagctctgggactggaacctccataat
ctgacgatcaaggaagggaaaatgtactttgcttttaatcccaaattgtgtgtttctgaa
atttatcgaatggaggaagtatctggaactaaaggtcgtcaaagcaaaggggacataaac
actaggaacaatggagaaagagcctcttgtgaaagtgacgttttgcatttcatttccaac
actacaatgaagaaccggattaagctaacatggcaacgatatcgtcctcctgattacagg
gatcttattagctttactgtttacttcaaagaggcaccatttaagaatgttaccgagtat
gatgggcaagatgcatgtggctctaacagctggaacatggttgatgtggacctccctccg
aataaggatgtcaaacctggaattttactgcagggactgaaaccctggactcaatatgct
atctacgtcaaagcagttactctcacaatggtggagaatgaccacatccggggagcaaaa
agtgaaattgtgtatattcgtaccaaagctgcagttccttctattcccttggatgttatt
tcagcatctaactcatcctcccagctaattgtgaagtggaatcctccttccctcccaaat
ggtaacttgtcctactacatagtaagatggcagcggcaacctcaagatagttacctctac
cgacacaattattgctccaaagacaaagttcctattagaaagtatgctgacggcaccatt
gatgttgaagaggttactgaaaatccgaaaactgaagtctgtggtggggagaaaggacct
tgctgtgcttgtcctaagacggaggctgagaagcaagcagagaaagaagaggccgagtac
agaaaagtctttgagaattttctgcacaactccatctttgtacccagacccgaacggagg
cgtagggatgtctttcaaattgccaattccacgttgcccagtcggaacaggaacaccaca
atggcagatcacttcaccaatatgtcagacacagaagagattgaatctgaatacccattc
tttgagagcagagtggataataaagagaggactttaatttctcatctcaggccttttact
ttgtaccgaattgatattcatagctgcaaccacgaagctgatactcttggctgtagtgct
tctaactttgtctttgcaaggaccatgccagcagaaggagcagataatattcctgggcca
gtgctgtgggaaccaagaccagataatactgtctacttgaagtggtcagaacctgaaaat
cccaatggactgatattaatgtatgaaataaagtatggtcagcaggtagaggatcagcgg
gaatgtgtttccagacaggaatacaggaaatttggaggggccaggcttacccggttgaat
cccgggaactattcagcccgtgttcaggccacctctctttccgggaatggatcatggact
gaccctgtattcttctatgtcccagccaaaccacctgactacgaaaacttcattcactta
atgatcgctctccccatcgcaggattatttatacttggtggaatactgataatgtggtat
gtctacaataaaaaaagaaacagtgacagattagggaatggagttctatatgcatctgtc
aatccagagtacttcagtgctgcagatgtgtatgttccagatgagtgggaggtacctcga
gagaagatcaccatgagtcgagaacttgggcagggttcatttgggatggtatatgaagga
gttgcaaagggcgtggtgaaagatgagcctgaaaccagggtagccatcaaaacagtcaat
gaagcagcaagcatgcgggagagaattgaatttctcaatgaagcttcagtaatgaaagaa
ttcaattgtcatcatgtggtgcgtttgcttggagtagtgtcccagggccagccaacatta
gtcatcatggaattgatgacacgaggggatctcaaaagttacctcagatctctgaggcca
gagacagagaataatccatgccagatgcttccaaccttaaagaagatgattcagatggct
ggagagattgctgatggcatggcatatctcaatgccaacaagtttgtccacagagatctt
gctgcaaggaattgcatggttgccgaagatttcaccgtcaaaatcggagattttggcatg
acaagagatatctatgagacagattactaccgaaaaggaggtaaaggattattacctgtt
cgctggatgtctccagagtcacttaaggatggagtcttcacaacacattctgatgtttgg
tcctttggtgttgtcctctgggagattgcaacattagcagagcagccctatcagggcatg
tctaatgaacaagttctccggtttgtaatggagggtggccttctagagaaaccagacaac
tgccccgatatgctgtttgaattgatgcgtatgtgctggcagtacaatcccaaaatgaga
ccttcttttctggagatcatcggcagcatcaaagatgagctggaccccagcttcaaggag
gtttccttcttctacagtgaagagaataaaccaccagacacagaagagctggacttagag
actgagaacatggagagcattcccttagacccttcctccaccctccagccggctgacaaa
ctctcaggacacaaagccgagaatgggcctggtgtggtggtcctcagggccagctttgat
gaaaggcagccttacgcgcacatgaatggaggacgcaagaatgaaagggccttacctttg
ccccagtcttcggcctgctga
DBGET
integrated database retrieval system
