Phascolarctos cinereus (koala): 110193684
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Entry
110193684 CDS
T05867
Symbol
FPGS
Name
(RefSeq) folylpolyglutamate synthase, mitochondrial isoform X1
KO
K01930
folylpolyglutamate synthase [EC:
6.3.2.17
]
Organism
pcw
Phascolarctos cinereus (koala)
Pathway
pcw00790
Folate biosynthesis
pcw01100
Metabolic pathways
pcw01240
Biosynthesis of cofactors
pcw01523
Antifolate resistance
pcw04981
Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:
pcw00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
110193684 (FPGS)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
110193684 (FPGS)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
110193684 (FPGS)
Enzymes [BR:
pcw01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.17 tetrahydrofolate synthase
110193684 (FPGS)
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Paralog
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-GeneID:
110193684
NCBI-ProteinID:
XP_020821287
UniProt:
A0A6P5IGE7
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Position
Unknown
AA seq
588 aa
AA seq
DB search
MSWARCRALHAALRLAAGPPPGSGPVRRGLSARPVPQEPGMEYQDAVRTLNTLQTNAGFL
EQIKRERGDPQVQLEAMKHYLIRSGLQVEDLDQLKIIHVTGTKGKGSTCAFTERILRGYG
LKTGFYSSPHLVQVRERIRINGEPISPELFTKYFWRLYNRLEETKDGSCVSMPPYFRFLT
IMAFHVFLQEKVDLAVVEVGIGGAYDCTNIVRKPVVCGISSLGIDHVSILGDTIEKIAWQ
KGGIFKPGVPAFTVSQPDSPLEVLKDQARKLMCPLYLCPPLEAFEEEAQPLHLGLAGDHQ
RSNAALALQLARCWLQQQGHKGIGEMKATRLTSRRALPLAPVFHPTLPMKQGLQDTEWLG
RTQMLRRGALTWYLDGAHTTSSIQAGVRWFRRAVLNQEKLNNGPEVRVLLFNATGERDTA
ALLKLLQPCQFDYAVFCPNLTEVSPVGNADQQNFTVTLDHVLTRCLENQKQWNRLAEEKA
GVDPWLAQAPELGSGPLHGPLLLVPPAPRPLNANSLVFSCISHALQWISQGRDPHFQPPT
PPRGLHSHPVASSGAVLLKEASSIQVLVTGSLHLVGGVLKLLDPALSQ
NT seq
1767 nt
NT seq
+upstream
nt +downstream
nt
atgtcttgggcccgttgccgagctctgcacgcggcgttgcggctcgcggcagggcccccg
cccgggagcggaccggtgaggcgggggctgagtgcacgaccggtgccgcaggagcccggg
atggagtaccaggatgctgtgcggaccctcaacactctgcagaccaatgctggctttcta
gaacagatcaagcgagaacggggagacccacaggtccagctagaagccatgaagcattat
ttaattcgaagtgggctgcaggtagaggacttagatcagctgaagatcatccatgtgact
gggaccaaagggaagggctccacttgtgccttcaccgaacgtattctccgtggctatggc
ctgaaaactggattctacagctctcctcatctggtgcaggttcgggagcgaatccgtatt
aatggtgaacccatcagccctgagctcttcaccaaatacttctggcggctctacaatcgt
ctagaggagactaaggatggcagttgtgtcagcatgcccccttacttccgcttccttacc
atcatggccttccatgtgttcctccaagagaaggtggacctagcagtggtagaggtgggc
attggtggtgcttatgactgtaccaacattgtcaggaagccagtggtgtgtgggatatcg
tctctgggcatagaccatgtcagcatcctgggtgacactattgagaagattgcatggcag
aaagggggcatctttaagcctggtgtcccagctttcactgtgtcccagccagactccccc
ctggaggttctgaaagaccaagcccgaaagctcatgtgtccgctgtacctgtgcccccca
ctggaggcctttgaggaagaagctcagccgctgcacctggggttggcaggcgatcaccag
cggagcaacgctgccctggctctgcagctggcccgctgctggctccagcaacagggccac
aagggtattggggagatgaaggcaaccaggctgacctcccggcgagccctgcccctggct
cctgtgttccatcccaccctgcccatgaagcaggggctgcaggacacagagtggctaggc
cggacacagatgttgagacgaggcgccctcacctggtacttggacggggctcacaccacc
agcagcattcaggcaggtgtgcggtggttccgccgtgcagtgctcaaccaggagaagctt
aacaatggccccgaggttcgggttttgctcttcaatgccactggagaacgggacacagcg
gctctactcaaactgctgcagccgtgccagtttgactatgctgtcttctgccccaacctg
actgaagtatctcctgtgggaaatgcagaccagcagaactttacggtcaccctggaccac
gtgctgacacgctgtctggagaaccagaaacagtggaaccgactggcagaggagaaggca
ggcgtggacccctggttggcccaggccccagaactcggcagtggacccctgcatgggcct
cttctcctggttcccccagctccccggcctctcaacgccaactctctggtcttcagctgc
atctcccatgccctgcaatggatcagtcagggccgggacccccactttcagccccccacc
cctccccgggggcttcactcccaccctgtggccagtagtggggctgtcctcctcaaggaa
gcctcctccatccaggttctggtcactggcagtcttcacctggtgggtggtgtcttaaag
ctccttgatcccgcactgtcccagtag
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