Phascolarctos cinereus (koala): 110196914
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Entry
110196914 CDS
T05867
Symbol
PDE10A
Name
(RefSeq) cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
KO
K18438
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10 [EC:
3.1.4.17
3.1.4.35
]
Organism
pcw
Phascolarctos cinereus (koala)
Pathway
pcw00230
Purine metabolism
pcw01100
Metabolic pathways
pcw04024
cAMP signaling pathway
pcw05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
pcw00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
110196914 (PDE10A)
09130 Environmental Information Processing
09132 Signal transduction
04024 cAMP signaling pathway
110196914 (PDE10A)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
110196914 (PDE10A)
Enzymes [BR:
pcw01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.17 3',5'-cyclic-nucleotide phosphodiesterase
110196914 (PDE10A)
3.1.4.35 3',5'-cyclic-GMP phosphodiesterase
110196914 (PDE10A)
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Ortholog
Paralog
GFIT
Motif
Pfam:
PDEase_I
GAF
GAF_2
GAF_3
SpoVT_C
HD
DUF7334
Motif
Other DBs
NCBI-GeneID:
110196914
NCBI-ProteinID:
XP_020826047
UniProt:
A0A6P5IV72
LinkDB
All DBs
Position
Unknown
AA seq
1148 aa
AA seq
DB search
MSNPEKQLLSRPQAPLSADGKRLRSGHYRLHSDLGGGGGNGQGGDGSSAPKVGNARGFPL
LLARADLGTDCPGPGAACFSSCGTRGGGGGCSSRNGSGVVPRSPFSVPSSSSPFPSSSPS
SFYFLPPPPPPPPPPLLPSSSCFHLPAGLQGREAAAAVAAARGGGGRRGGGDVGGGGGRG
EETAPLIVHPSNSSSSSSSSGSGSGSRRRRLFFSPPSLQGLLLPVGPRLQQQQPPPPPQP
PRLLLSSASCSLWSYNFLGAAGAAGAGGGVGGGDRGYTSSSRSKIQRRQQRQQPPRGSFF
FAASSPLSLGSDMEDGSSRNASCFRRFTECFLNPSLTDEKVKAYLSLHPQVLDEFVSESV
SAETVEKWLKRKTNKPEDEGVCNEITRSTVTQKTLKSDKRIDRLSQNLARSGINPLRLPS
DSPGKPLSTGDTNMQGVVYELNSYIEQRLDTGGDNQLLLYELSRLIKIATKADGFALYFL
GDCNNSLCMFTPPGVKEGKPRLIPAGPITHGTTISAYVAKSRKTMLVEDILGDERFPKGI
GLELGTRVQSVLCLPIVTAIGDLIGILELYRNWGKEAFHICHQEVATANLAWASVAIHQV
QVCRGLAKQTELNDFLLDVSKTYFDNIVAIDSLLEHIMIYAKNLVNADRCALFQVDHKNK
ELYSDLFDIGEENEGKPVFKKTKEIRFSIDKGIAGQVARTGEVLNIPDAYADPRFNREVD
LYTGYTTRNILCMPIVSRGSVIGVVQMVNKISGSAFSKTDENNFKMFAVFCALALHCANM
YQRIRHSECIYRVTMEKLSYHSICTAEEWQNLMHFTVPASLHKEIELYHFDISPFEEMWP
AIFVYMVHQSCGTACFDYEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNQGL
FTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSLLQLEG
HNIFSSLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEMYQTGSLNLNNQAHRDRVIG
LMMTACDLCSVTKLWPVTRLTANDIYAEFWAEGDEMKKFGIQPIPMMDRDKKDEVPQGQL
GFYNAVAIPCYTTLMEIFPPTGPLLRACRDNLGQWEKIIRGEESLIWLPNQTGTPETSSS
LPLKIDQQ
NT seq
3447 nt
NT seq
+upstream
nt +downstream
nt
atgtccaaccccgagaagcagcttttatcccgcccccaggcccctctgtctgcagacggg
aaaaggctcagatccggccactaccgactgcactcggatctcggcggcggcggcggcaac
ggccagggcggggacggttctagcgctccgaaggttgggaacgcccgcggtttccccttg
cttctggcccgcgcagacctgggcacagattgtccgggccccggcgccgcttgcttctct
tcgtgcggtactcgcggcggcggcggcggctgcagcagtcgtaacggcagcggggtcgtc
cctcgatctcctttctccgttccctcttcctcctccccctttccgtcctcttctccatct
tccttttacttcttgccgcccccgcctccccctcctcctcctcctcttctcccctcctcg
tcttgctttcacctcccagcgggtctccaaggaagggaggcagcagcagcagtagcagca
gcaagaggaggaggaggacgtagaggaggaggagatgttggaggaggaggaggaagagga
gaagaaacagctcccttgatcgtccacccgagcaatagtagtagcagtagcagcagcagc
ggcagtggcagcggcagcaggaggcggcggctgtttttctctcctccttccctccagggt
ttactgctcccagtcggcccccggctgcagcagcagcagccgccaccaccaccgcagcca
cctcggcttctcctttcctcagcctcctgcagcctgtggtcctacaatttcctcggcgct
gcaggcgctgccggcgccggcggtggggtcggaggcggcgaccggggttacaccagcagc
agccgcagcaaaattcagcggcggcagcagcggcagcaaccgcctagaggctccttcttc
ttcgctgcctcctcccccttgtcactagggtcagacatggaagatggatcttctagaaat
gcaagctgctttagaaggtttacggagtgtttcttgaacccgagtctgacagatgaaaaa
gtgaaggcctatctttctcttcacccccaggtactcgatgaatttgtttctgaaagtgta
agtgccgagacagttgagaaatggctgaagaggaaaaccaacaaaccggaagatgaagga
gtttgtaatgaaatcacccggtcaactgtgacccagaagacattgaagtcagacaagaga
attgacagactatctcagaatctagcaaggtcaggtataaacccactgagattgccatca
gactctccagggaaacctttaagtaccggggatacaaacatgcaaggcgttgtatatgaa
ctaaacagctatatagaacaacggttggatacaggaggagacaaccagctactgctctat
gaattgagtagactcatcaaaatagccacaaaagcagatggatttgcactgtatttcctg
ggagactgcaataatagtctatgtatgttcacaccacctggagtaaaggaaggaaaacca
cgactcatcccagctgggccaattacccatggtacaacaatatctgcttatgtagccaaa
tcaaggaaaacaatgctagtagaagatatccttggggacgaacgatttcccaaaggtatt
ggactggaattggggacacgtgtccagtctgttctttgtttaccaattgtcaccgcgatt
ggtgacctcattggtatccttgaactatatcggaactggggcaaagaagctttccatatc
tgtcaccaagaggttgccacagcaaatcttgcctgggcctcagtagcaatacatcaagtg
caagtatgcagaggccttgccaaacagactgaattgaatgacttcctacttgacgtatca
aagacctattttgataacatagttgcaatagattctctacttgaacacataatgatatat
gcaaaaaacttggtgaatgcagatcgttgtgcactattccaggtagaccataagaacaaa
gaattatattcagacctttttgacattggggaggaaaatgaagggaagcctgtctttaag
aagaccaaagaaataagattttcaattgataaaggaatagctggtcaggtggctagaaca
ggggaggtccttaacatcccagacgcctatgcagacccacgctttaacagggaagtagac
ctatacacaggttatactacacggaatattttgtgtatgcctattgtgagtcgagggagt
gtaatcggcgttgtacagatggtaaacaaaataagtggaagtgccttctccaaaactgat
gaaaacaactttaaaatgtttgcagtcttttgtgctttagccttacactgtgctaatatg
tatcaaagaattcgccattcagagtgcatttaccgagtaactatggaaaagctttcctat
cacagcatatgtactgcagaagaatggcaaaacctcatgcatttcacagtcccagcaagc
ctccacaaagaaattgaattgtatcattttgatatcagtccttttgaggaaatgtggcct
gccatttttgtctacatggtacatcagtcctgtgggacagcctgctttgactatgaaaag
ttatgtcgttttattatgtctgttaagaaaaactatcgacgagttccttatcacaactgg
aaacatgcagttactgtggcacattgcatgtatgccatacttcagaataatcaagggctt
tttacagatctagagcgaaaaggacttctgattgcatgcctatgtcatgacctggaccac
aggggattcagtaatagctaccttcagaagtttgatcaccctttggcagctctctattcc
acctcaaccatggagcagcaccatttttcgcagacagtatccctcctacagttggaaggg
cacaatatcttctcctctctgagctccagtgaatatgagcaggtgctggagatcatccgc
aaagccatcatcgccacagaccttgctctgtactttgggaacagaaagcagttggaggag
atgtaccagacaggatcgctaaaccttaataatcaagcacatagagaccgggtaattggt
ctaatgatgactgcttgtgacctttgttctgtaacaaagctgtggccagttacaagattg
acagctaatgacatatatgcagagttctgggctgagggtgatgaaatgaagaaatttgga
atacagcctatccctatgatggacagagacaaaaaggatgaagtacctcaaggccaactc
ggcttctacaatgctgtagcgattccctgttatactacccttatggagatctttccccct
actggacccctgctccgggcttgcagggataatcttggccaatgggagaaaataattaga
ggagaggaaagtcttatatggcttccaaaccagacaggaactccagagacctctagctca
ctgcctttgaagattgatcaacaatga
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