Phascolarctos cinereus (koala): 110197059
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Entry
110197059 CDS
T05867
Symbol
ROCK1
Name
(RefSeq) rho-associated protein kinase 1 isoform X1
KO
K04514
Rho-associated protein kinase 1 [EC:
2.7.11.39
]
Organism
pcw
Phascolarctos cinereus (koala)
Pathway
pcw04022
cGMP-PKG signaling pathway
pcw04024
cAMP signaling pathway
pcw04062
Chemokine signaling pathway
pcw04071
Sphingolipid signaling pathway
pcw04270
Vascular smooth muscle contraction
pcw04350
TGF-beta signaling pathway
pcw04360
Axon guidance
pcw04510
Focal adhesion
pcw04519
Cadherin signaling
pcw04520
Adherens junction
pcw04530
Tight junction
pcw04611
Platelet activation
pcw04670
Leukocyte transendothelial migration
pcw04810
Regulation of actin cytoskeleton
pcw04921
Oxytocin signaling pathway
pcw05135
Yersinia infection
pcw05163
Human cytomegalovirus infection
pcw05200
Pathways in cancer
pcw05205
Proteoglycans in cancer
pcw05206
MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:
pcw00001
]
09130 Environmental Information Processing
09132 Signal transduction
04350 TGF-beta signaling pathway
110197059 (ROCK1)
04071 Sphingolipid signaling pathway
110197059 (ROCK1)
04024 cAMP signaling pathway
110197059 (ROCK1)
04022 cGMP-PKG signaling pathway
110197059 (ROCK1)
09133 Signaling molecules and interaction
04519 Cadherin signaling
110197059 (ROCK1)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
110197059 (ROCK1)
04520 Adherens junction
110197059 (ROCK1)
04530 Tight junction
110197059 (ROCK1)
09142 Cell motility
04810 Regulation of actin cytoskeleton
110197059 (ROCK1)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
110197059 (ROCK1)
04670 Leukocyte transendothelial migration
110197059 (ROCK1)
04062 Chemokine signaling pathway
110197059 (ROCK1)
09152 Endocrine system
04921 Oxytocin signaling pathway
110197059 (ROCK1)
09153 Circulatory system
04270 Vascular smooth muscle contraction
110197059 (ROCK1)
09158 Development and regeneration
04360 Axon guidance
110197059 (ROCK1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
110197059 (ROCK1)
05206 MicroRNAs in cancer
110197059 (ROCK1)
05205 Proteoglycans in cancer
110197059 (ROCK1)
09172 Infectious disease: viral
05163 Human cytomegalovirus infection
110197059 (ROCK1)
09171 Infectious disease: bacterial
05135 Yersinia infection
110197059 (ROCK1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pcw01001
]
110197059 (ROCK1)
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
pcw03036
]
110197059 (ROCK1)
Enzymes [BR:
pcw01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.39 ROCK-subfamily protein kinase
110197059 (ROCK1)
Protein kinases [BR:
pcw01001
]
Serine/threonine kinases: AGC group
DMPK family [OT]
110197059 (ROCK1)
Chromosome and associated proteins [BR:
pcw03036
]
Eukaryotic type
Centrosome formation proteins
Kinases and associated factors
110197059 (ROCK1)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Rho_Binding
PH_MRCK
PH
C1_1
Par-4_C
Pkinase_C
CC_Bre1
Motif
Other DBs
NCBI-GeneID:
110197059
NCBI-ProteinID:
XP_020826308
UniProt:
A0A6P5IZ22
LinkDB
All DBs
Position
Unknown
AA seq
1285 aa
AA seq
DB search
MKAEDYEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDSAFFWEERDIMAF
ANSPWVVQLYYAFQDDRYLYMVMEYMPGGDLVNLMSNYDVPEKWARFYTAEVVLALDAIH
SMGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGTPDYISPEVLKSQG
GDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNSLTFPDDNDISKEAK
NLICAFLTDREVRLGRNGVEEIKRHLFFKNDQWAWETLRDTVAPVVPDLSSDIDTSNFDD
LEEDKGDEETFPIPKAFVGNQLPFVGFTYYSNRRYLSVSSANSNDNRTTSNVDKSLQESL
QNTIYKLEEQLHNEIQLKDEMEQKCRTSNIKLDKIMKELDEEGNQRKNLESTVSQIEKEK
MLLQHRVNEYQRKIEQENEKRRNVENEVSTLKDQLEDLKKISQNSQLTNEKMAQLQKQLK
EANDLLRTESDTAARLRKSHTELSKSVSQLESLNRDLQERNRILETTKSQVDKDYYQLQA
ALEAERRDRSHGSEMIGDLQARITSLQEEVKHLKHNLERMEGERKEAQDMLNHSEKEKNN
LEIDLNYKLKSLQQRLEQEVNEHKVTKARLTDKHQSIEEAKSVAMCEMEKKLKEERAARE
RAENRVVHIEKQCSMLDVDLKQSQQKLEHLAEHKERMEDEVKNLTLQLEQESNKRLLIQN
ELKTQAFEKDNLKGLEKQMKQEINTLLEAKRLLEFELAQLTRQYCGNEGQMRELQDQLEA
EQYFSTLYKTQVKELKEDIEEKNRENLKKIQELQNEKETFAAQLDLAETKAESEQLARRL
LEEQYFELTQECKKAASRNKQEITDKDHTVSRLEEINSTLTKDIELLRKENEEFTEKMKE
QEDYKLKKEEEITNLKASFEKNINTERTLKIQAVNKLAEIMNRKDFKIDRKKANTQDLRK
KEKENRKLQLELNQEREKFNQMVVKHQKELNEMQAQLVEECTHRNELQMQLASKESDIEQ
LRAKLLDLSDSTSVTSFPSADETDGNLPESRIEGWLSVPNRGNIKRYGWKKQYVVVSSKK
ILFYNDEQDKEQSNPSMVLDIDKLFHVRPVTQGDVYRAETEEIPKIFQILYANEGECRKD
LEMEPVQQAEKTNFQNHKGHEFIPTLYHFPANCEACAKPLWHVFKPPPALECRRCHVKCH
RDHLDKKEDLISPCKVSYDVTSARDMLLLACSQDEQKKWVTHLVKKIPKNPPSSFVRASP
RTLSTRSSANQSFRKVVKNTSGKTS
NT seq
3858 nt
NT seq
+upstream
nt +downstream
nt
atgaaagctgaagattatgaagtagtgaaagtgattggtagaggtgcatttggagaagtg
caattggtaaggcataaatccaccaggaaggtgtatgctatgaagctgctgagcaaattt
gaaatgattaagagatcagattctgctttcttctgggaagaacgggacattatggctttt
gctaacagcccctgggtggttcagctttattatgcattccaagatgatcggtatctctac
atggtaatggaatatatgcctggtggggatcttgttaatttaatgagcaactatgatgtg
cctgaaaagtgggcccgcttctatactgcagaagtagttcttgctttggatgcaatccat
tcaatgggctttattcatagagatgtgaagcctgacaacatgctgctggataaatctggt
cacttgaagctagctgattttggtacttgtatgaagatgaataaggaaggtatggtacga
tgtgatacagcagttggaacacctgactatatttctcctgaagtattaaaatcccaaggt
ggtgatggctattatgggcgagaatgtgactggtggtcagttggggtatttttatatgaa
atgcttgtaggtgatacaccattttatgcagattcactggttgggacatatagcaaaatt
atgaaccataagaattctcttaccttccccgatgataatgatatctcaaaagaagcaaaa
aatcttatttgtgccttccttacagacagggaagtgagattaggacgaaatggtgtggaa
gaaatcaaacgacatctcttcttcaaaaatgatcagtgggcgtgggaaactcttcgagat
actgttgcacctgttgtacctgatctcagtagtgacattgatactagtaattttgatgac
ttagaagaagacaagggagatgaagaaacattccctattccaaaagcttttgttggcaat
caactaccttttgtaggatttacatattatagcaatcgtagatatttatctgtatcttca
gcaaattctaatgataacaggaccacctctaatgtggataaaagcttgcaggagagtttg
caaaacacaatctataagctggaagaacaactgcataatgaaatacagttaaaagatgaa
atggagcagaagtgcagaacttcaaacataaaactagacaagataatgaaagaactggat
gaagagggaaatcagagaaaaaatttagaatccacagtgtctcagattgagaaagagaaa
atgttgctgcagcacagagttaatgagtaccaaagaaaaatagaacaggagaatgagaag
agacggaatgttgaaaatgaggtttctacattaaaagatcagttggaggacctgaagaaa
attagtcagaattctcagcttacaaatgagaaaatggcacagttacagaagcaactgaaa
gaagccaacgacttactgaggacagaatcggacacagcagcaaggttaagaaagagccac
acagaattaagcaaatcagtaagtcagttagagtccctgaacagagacctgcaagagcga
aacagaattttagagacaaccaaatcacaagtggacaaagattattaccagcttcaggct
gcattagaagctgaacggagagaccgaagtcatggatctgagatgattggagatctccaa
gctcgaattacgtctttacaagaggaagttaaacaccttaaacataatcttgaaagaatg
gaaggggaaagaaaagaggctcaagacatgcttaatcattcagaaaaggaaaagaataat
ttggaaatagatttaaactacaagctaaaatcgttacagcaaagattagaacaggaagta
aatgagcataaagtgactaaagcccgtttaactgacaagcatcaatctattgaagaggca
aaatcagttgcaatgtgtgaaatggaaaagaaactgaaggaagagagagcagcacgagag
agagccgaaaatagagttgttcacattgaaaagcagtgttccatgttagatgtcgacttg
aaacagtctcagcagaaactggagcatttggcagaacacaaagaaagaatggaggatgaa
gttaagaatctaacactgcagctggagcaagaatcaaataagaggttactgatacagaat
gaattgaaaactcaagcttttgagaaggacaatttgaaagggttagaaaagcaaatgaaa
caagagatcaatacattattagaagctaagagattattggaatttgaactagctcagctc
acaagacaatattgtggaaacgaaggacagatgcgggaactacaggatcaacttgaagct
gaacaatatttttcaacactttataaaactcaggtaaaggaacttaaagaggacattgaa
gaaaaaaatcgagaaaatctaaagaaaatacaggaactgcaaaatgaaaaagaaacgttt
gctgcacagttagacctggcagaaacaaaagctgaatcagagcaattggctcgacgtctc
ctagaagaacaatattttgaattgacccaagagtgtaagaaagcagcttcacgaaataaa
caagaaattacagataaagatcacactgtcagtcggctggaagaaataaacagtacatta
accaaagatattgaactattaagaaaggaaaatgaagagtttactgaaaaaatgaaggaa
caagaagattataaattgaagaaagaagaggagatcactaatcttaaagcttcttttgaa
aagaacattaatactgaaagaaccctaaaaatacaggctgttaacaagttggcagaaata
atgaatcgcaaagattttaaaattgatagaaagaaggctaatacacaagatttgagaaag
aaggaaaaggaaaacagaaaattacaattggaactcaaccaagagagagagaaattcaat
cagatggtagtgaaacaccagaaggaactcaatgaaatgcaagcgcaattggttgaagag
tgcacacacaggaatgaacttcagatgcagctggctagcaaagagagtgacatagagcag
ttgcgtgcaaaacttttggacctttcagattctactagtgttactagttttcctagtgcc
gatgaaactgatggaaaccttccagaatcaagaattgaaggttggctctcagtcccaaac
agaggaaatataaaacgatatggctggaagaaacagtatgttgtagtaagcagcaaaaaa
attttgttctacaatgatgaacaggataaggaacagtcaaatccatctatggtactagac
atagacaaactattccatgttcgacctgtaacccaaggtgatgtgtatagagcagaaact
gaagaaatccctaaaatattccagatactatatgcaaatgaaggtgaatgtaggaaagat
ttggagatggagccagtacaacaagctgagaagactaattttcagaatcacaaaggccat
gagtttattcctacactctatcactttccagccaactgtgaggcttgtgccaaacctctc
tggcatgtttttaagccaccccctgcccttgaatgtcgaagatgccatgtcaagtgccac
agagatcacttagacaaaaaagaagatttaatttctccatgcaaagtgagttatgatgta
acatcagcaagagatatgttgctgttagcatgttctcaggatgaacagaagaaatgggta
acccatttagtaaagaagattcctaagaatccaccatccagttttgttcgtgcatctcct
agaacactttctaccagatctagtgcaaatcagtctttccggaaagttgtcaaaaatacc
tctgggaaaactagctaa
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