Phascolarctos cinereus (koala): 110197314
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Entry
110197314 CDS
T05867
Symbol
TOP2B
Name
(RefSeq) DNA topoisomerase 2-beta isoform X1
KO
K03164
DNA topoisomerase II [EC:
5.6.2.2
]
Organism
pcw
Phascolarctos cinereus (koala)
Pathway
pcw01524
Platinum drug resistance
Brite
KEGG Orthology (KO) [BR:
pcw00001
]
09160 Human Diseases
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
110197314 (TOP2B)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
pcw03032
]
110197314 (TOP2B)
03036 Chromosome and associated proteins [BR:
pcw03036
]
110197314 (TOP2B)
Enzymes [BR:
pcw01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.2 DNA topoisomerase (ATP-hydrolysing)
110197314 (TOP2B)
DNA replication proteins [BR:
pcw03032
]
Eukaryotic type
DNA Topoisomerases
110197314 (TOP2B)
Chromosome and associated proteins [BR:
pcw03036
]
Eukaryotic type
Chromosome condensation proteins
Other regulators of chromosome condensation
110197314 (TOP2B)
Centrosome formation proteins
Centriole proteins
110197314 (TOP2B)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
DNA_topoisoIV
TOPRIM_C
DNA_gyraseB
DTHCT
Toprim
HATPase_c
DUF7180
Motif
Other DBs
NCBI-GeneID:
110197314
NCBI-ProteinID:
XP_020826754
UniProt:
A0A6P5J6W4
LinkDB
All DBs
Position
Unknown
AA seq
1633 aa
AA seq
DB search
MAKSGGGGAAAAAAGGAGGAGGAGGGGAGGGLTWVTLFDQNNAAKKEESESSNKNDSSKK
LSVERVYQKKTQLEHILLRPDTYIGSVEPLTQSMWVYDEDVGMNCREVTFVPGLYKIFDE
ILVNAADNKQRDKNMTCIKISIDPESNIISIWNNGKGIPVVEHKVEKVYVPALIFGQLLT
SSNYDDDEKKVTGGRNGYGAKLCNIFSTKFTVETASKEYKHSFKQTWVNNMMKTSEPKIK
YFDGDDYTCITFQPDLSKFKMEKLDKDIVALMTRRAYDLAGSCKGVKVMFNGKKLPVNGF
RSYVDLYVKDKLDETGVALKVIHELANERWDVCLTLSEKGFQQISFVNSIATTKGGRHVD
YVVDQIVGKLIEVVKKKNKAGVSVKPFQVKNHIWVFVNCLIENPTFDSQTKENMTLQPKS
FGSKCQLSEKFFKAASNCGIIESILNWVKFKAQTQLNKKCSSVKYSKIKGIPKLDDANDA
GGKHSLECTLILTEGDSAKSLAVSGLGVIGRDRYGVFPLRGKILNVREASHKQIMENAEI
NNIIKIVGLQYKKSYEDAESLKTLRYGKIMIMTDQDQDGSHIKGLLINFIHHNWPSLLKH
GFLEEFITPIVKASRNKQELSFYSIPEFDEWKKHIENQKAWKIKYYKGLGTSTAKEAKEY
FADMERHRILFRYAGPEDDAAITLAFSKKKIDDRKEWLTNFMEDRRQRRLHGLPEQFLYG
TATKHLTYNDFINKELILFSNSDNERSIPSLVDGFKPGQRKVLFTCFKRNDKREVKVAQL
AGSVAEMSAYHHGEQALMMTIVNLAQNFVGSNNINLLQPIGQFGTRLHGGKDAASPRYIF
TMLSTLSRLLFPSVDDNLLKFLYDDNQRVEPEWYMPIIPMVLINGAEGIGTGWACKLPNY
DAREIVNNVRRMLDGLDPHPMLPNYKNFKGTIQEIGQNQYAVSGEIFVVDRNTVEITELP
VRTWTQVYKEQVLEPMLNGTDKTPALISDYKEYHTDTTVKFVVKMTEEKLVQAEAAGLHK
VFKLQTTLTCNSMVLFDHMGCLKKYETVQDILKEFFDLRLNYYSLRKEWLVGMLGAESTK
LNNQARFILEKIQGKITIENRSKRDLIQMLVQRGYESDPVKAWKEAQEKAAEEEETQNQR
DDSSSDSGTTSGPDFNYILNMSLWCLTKEKVEELIKQRDTKGRELNDLKRKSPSDLWKED
LAAFVDELDKVEAQEREDALAGMSGKAIKGKVGKPKIKKLQLEETMPSPHGRRIIPQITS
AMKADASKKLLKKKKGDLDPTVVKVEFDDELGGAPAEGTGEDSLTTSTPAPKGPKPKREK
KEPGTRVRKTPLSSNKSSAKKVKKRNPWSDDESKSESDLEETEPVIIPRDSLLRRAAAER
PKYTFDFSEEEDDADEDDNNDLEELKVKSSPVTDDRDDEFIPSDGLDKDDYTFSPVKSKV
TPEKSSHDKKNQDFGNLFSFPSYSQKSEDDATKFDSGEEDSASVFSSSFALKSTEKPPSK
TVAAKKAKLSSDAPPKPKRLPKQKKIETTNSDSDSEFGIPKKTTAPKGKGRGAKKRKVSG
SENEGEYNPGRKTSKSTPGKKSKKASFDQDSDMDIFQADFPPEPPSLPRTGRTRKEVKYF
AESDEDVDFAMFN
NT seq
4902 nt
NT seq
+upstream
nt +downstream
nt
atggccaagtccggcggcggcggcgcggcggcggcggcggccggaggagccggcggagcc
gggggagccggcgggggaggagccggcggaggcctgacctgggtgactctttttgatcag
aacaatgctgcaaaaaaagaagagtcagaaagcagtaataaaaatgattcttcaaagaag
ttgtctgttgagagagtttatcagaagaaaacacaacttgaacacattctcctccggcct
gatacatacattggatctgtggagccattaactcagtcaatgtgggtttatgatgaagat
gtaggaatgaattgcagagaagttacttttgtaccaggcttatacaaaatctttgatgaa
attcttgttaatgcagctgacaataaacagagggataagaacatgacctgtatcaaaatt
tctattgatcctgaatctaacattatcagcatctggaataatggaaaaggcattcctgta
gtggaacacaaagtagaaaaagtctatgttcctgctttaatctttggacagcttttaaca
tctagtaactatgatgatgatgagaaaaaagttacaggtggtcgtaatggttatggtgca
aaactttgtaatattttcagtacaaaatttacagttgaaactgctagtaaagaatataaa
catagttttaaacagacctgggtgaataatatgatgaagacttctgagcccaaaattaaa
tactttgacggagatgactatacatgtataacattccaaccggatctgtccaaatttaag
atggaaaagctcgacaaagatattgtggccctcatgactagaagagcctacgacttggct
ggttcatgcaaaggggtcaaagtcatgtttaatgggaagaagttgcctgtaaatggattc
cgcagttacgtagacctttacgtaaaggacaaattggatgaaactggggttgccctgaaa
gttattcatgaacttgcaaatgaacgatgggatgtttgtctcacattgagtgaaaaaggc
ttccagcaaatcagctttgtaaatagtattgctacaacaaaaggtggaaggcatgtagat
tatgtagtggatcaaatcgttggcaaactgattgaagtagttaagaaaaagaacaaagct
ggagtatcagtgaagccctttcaagtaaaaaatcacatatgggtttttgtgaactgtctt
attgaaaatccaacttttgattctcagacgaaggaaaacatgaccctgcagcccaaaagc
tttgggtctaagtgtcagctatctgagaaatttttcaaagcagcttccaactgtggtatc
atagaaagtattctgaactgggtcaagtttaaagctcagactcaactgaacaagaagtgt
tcctcagtcaagtacagtaaaatcaaaggcattcccaaattggatgatgcgaatgatgca
ggtggtaaacattccctagagtgcacactcatattaacagaaggagattctgcaaaatca
ttggcagtttctgggttaggtgtgattggacgagacagatatggagtctttccacttagg
ggtaaaattcttaatgtgcgagaagcttcgcataagcagattatggaaaatgcagaaatc
aacaacattattaaaatagttggtcttcagtataagaagagttatgaagatgcagaatct
ctgaaaaccttgcgttatggaaaaattatgattatgactgatcaggatcaagatggctcg
catataaagggcttacttattaattttattcatcataattggccttcgcttttgaaacat
ggctttcttgaagagttcatcactcccattgtaaaggcaagcagaaataagcaggagctt
tccttctacagtatacctgagtttgatgagtggaagaaacatatagaaaaccagaaggcc
tggaaaataaagtactacaaagggttgggtaccagcacagctaaagaagcaaaggaatat
tttgctgacatggaaaggcatcggattttgtttagatatgctggtcctgaagatgatgca
gctattactctagcattcagtaaaaagaagattgatgatcgtaaagaatggttaacaaat
ttcatggaagatcgaagacagcgcaggttacatggcctgccagagcaatttttatatggt
acagccacaaaacatttgacttacaatgattttatcaacaaggagttgattcttttctca
aactctgacaatgaaagatctataccctctcttgttgatggctttaaaccaggtcaacga
aaagttttgtttacctgttttaagaggaatgataaacgggaagtcaaagttgctcagctg
gctggatcagttgctgagatgtctgcttatcatcatggagaacaagcactaatgatgact
atagtcaatttggcccagaactttgttgggagtaacaatattaatttgcttcaacctatt
ggtcagtttggaactaggcttcatggtgggaaagatgctgcaagtcctcgttatattttt
acaatgttaagcactctatcaaggctgcttttcccttctgtggatgacaacctgcttaag
ttcctttatgatgataaccagcgtgtagagcctgagtggtatatgcctattattcccatg
gttttaataaatggtgctgagggcattggtactggatgggcctgtaaacttcctaactat
gatgctagagaaattgtgaacaatgtcagacggatgttggatggcttggaccctcatccc
atgcttccaaactacaaaaattttaaaggaacaatccaagaaattggccagaaccagtat
gctgttagtggtgaaatatttgtagtggatagaaatacagtagagatcacagagcttccg
gttagaacatggacacaggtatacaaagagcaggttttagaacctatgctgaacggaaca
gacaaaacaccagcattaatttctgattataaagaatatcatacagatacaactgtgaaa
tttgtggtgaagatgacagaggaaaaacttgtgcaggcagaagctgctgggctgcataaa
gtcttcaagcttcagaccactcttacttgtaattctatggtgctgtttgaccatatggga
tgtctgaagaagtatgagactgtacaagatattctgaaggagttctttgatttaaggtta
aattattatagtttacgtaaggagtggcttgtgggaatgttgggggcagaatccaccaag
ctaaacaatcaagctcgcttcattctagagaagatacaagggaaaatcactatagagaat
aggtcaaagagagatttgattcaaatgttagtccagagaggttatgaatctgacccagtg
aaagcctggaaagaagcacaagaaaaggcggcagaagaggaagaaacacaaaaccagcgt
gatgatagttcctctgattcgggcactacctcaggccctgattttaactacatcttaaat
atgtctttgtggtgtcttactaaagaaaaagttgaagaactgattaaacagagagataca
aaagggagagaactcaatgaccttaaaagaaaatctccttcagatctctggaaagaagat
ttagcagcttttgttgacgaacttgataaagtggaggcccaagaacgagaggatgctttg
gctgggatgagtggcaaagcgataaagggtaaagttggcaagcccaagataaagaagctt
cagctggaagagactatgccctcgccccatggcagaaggatcattccacagattacctct
gccatgaaggctgatgccagtaaaaagttgctaaagaagaagaagggtgatctcgatcct
acggtggtaaaagtggaatttgatgatgaattaggtggagcaccagcagaaggtacagga
gaagattcattgacaacatctactcctgcacctaaagggcccaaacccaaaagggagaaa
aaagagccgggtaccagggtgagaaaaacacctctgtcttctaataaatccagtgcaaag
aaagtgaagaaaagaaacccttggtctgatgatgaatccaaatcagaaagtgacttggaa
gaaaccgaacctgtgattattccaagagattctctgcttagacgagctgctgcggaaagg
cctaaatatacttttgatttttcggaagaggaagatgatgctgatgaagatgacaataat
gatttagaggaattgaaagtaaaatcatctcctgtgacagatgacagagatgatgagttc
attccctcagatggtttagataaggatgactatactttttctccagtcaaatcaaaagta
actccagaaaaatcctcacatgacaagaaaaaccaggactttgggaacctgttctcattc
ccttcttattcacagaagtcagaagatgatgcaacaaaatttgacagtggtgaagaggat
tctgcttctgttttttcatcttcatttgctctcaaatcaacagaaaaacctccaagtaaa
acagtggctgccaaaaaggcaaagctatcttcagatgcaccacctaagcccaagagactt
cccaaacagaagaaaatagaaactacaaactctgactcagattcagaatttggcattcca
aagaagacaactgcaccaaaaggtaaaggccgaggtgcaaaaaaacggaaagtatctggc
tccgaaaatgaaggcgaatacaatcctgggagaaaaacgtccaagtccacacctggcaag
aaatccaagaaggcctccttcgaccaggattcagacatggacatcttccaggcagacttt
ccccctgaaccaccatctcttcctcggacaggtcgcaccagaaaagaagtaaaatatttt
gcagagtctgatgaagatgttgattttgcaatgtttaattaa
DBGET
integrated database retrieval system
