Phascolarctos cinereus (koala): 110198913
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Entry
110198913 CDS
T05867
Symbol
SETX
Name
(RefSeq) LOW QUALITY PROTEIN: probable helicase senataxin
KO
K10706
ATP-dependent RNA/DNA helicase, senataxin [EC:
5.6.2.5
5.6.2.3
]
Organism
pcw
Phascolarctos cinereus (koala)
Pathway
pcw05014
Amyotrophic lateral sclerosis
Brite
KEGG Orthology (KO) [BR:
pcw00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
110198913 (SETX)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03021 Transcription machinery [BR:
pcw03021
]
110198913 (SETX)
Enzymes [BR:
pcw01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.3 DNA 5'-3' helicase
110198913 (SETX)
5.6.2.5 RNA 5'-3' helicase
110198913 (SETX)
Transcription machinery [BR:
pcw03021
]
Eukaryotic type
RNA polymerase II system
Other transcription-related factors
Transcription termination factor
110198913 (SETX)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
AAA_11
AAA_12
AAA_19
AAA_30
AAA_22
ResIII
nSTAND3
UvrD_C_2
Helicase_RecD
AAA_16
Motif
Other DBs
NCBI-GeneID:
110198913
NCBI-ProteinID:
XP_020829201
UniProt:
A0A6P5JDM0
LinkDB
All DBs
Position
Unknown
AA seq
2753 aa
AA seq
DB search
MSTCRWCTPGGESTVDFLKSYAFGTLPCEVLTANEDLCYCLECVAEYHKARDTLPSLHEI
LWEFETTRLINHFEKSMKGEIEEDDELFIVDDNGETQLFGFTGQDFENKLRVPLLEILKY
PYLLLDEHVNELCVEALCRMEQANCSFQVFDKHPGIYLFLVHPNEMVRRWAILTARNLGK
VDRDDYYDLQEVLTCLFRVIELGLLESPDIYTSSEFEKGKLVLLPSHMYDTSNYKNYWLG
ICMLLTILEEQAMDSLLLGSDKQNDFMQSILHTMEKQSDEDSVDPFWPALHCFMVILDRL
GSKVWGQLIDPIEAFQTIINNVSYNKEIQNIRNSSTRTKLEPESDLEEMVTCSQIVYNYN
PEKTKKDSGWRSAICPDYCPNMYEEMETLASVLQSDIGQDMRVHNSTFLWFIPFVQSLMD
LKDLGVAYIVEVIHHLYSEVKDVLNQKVAVCDTVTEFFLLILVSVIELHRNKNCLHLLWV
SSQQWVEAVVKCAKLPTTAFARSAEKTSGSYSKGATVISSMPLHSIPSNSVQLACVQLIR
SLLREGCQLGQQTLCKQFLDKLNLCLRGNLSLGWHLNSQETLELQTCLKQIIKSKKVRGL
PCSTFVDRTITCKNPSVIYTKEESDTTMEKSKKDTCSQDSSSPSFSKEPPRADVCQGQES
PSLRRNYSWEEENRQTYLKESKLDDHFSNKSCSKQEKNPDANRSHNHEILDNVEKQKCTE
ENSSTNIQQNLASENNGVEGGYDRTANFQACLMTTDSRSDSPQNESSSSDDSRSKNDSGF
RNSKFRSKAQKDELCAKLLQVMKEHKKTTMVASVNNLESKQSSTNLESHNSCKDVDVQKG
FALIQKTQTEPCIIPEETTNEEQESRNGYSLVEKKKSDDRQLDPLTFHKKDNLPQESDSD
EDDDDMVSLKTIRNTLLKKKCQLIHHTDRHESKDSNCEETNNDNDYVPHNLTREEVPPQN
FKFNTLTDSEVDKDLDIPFIVHTSVLNFPSDSTQENSYQLRRKVKNVRSLSVVNEITELT
SVVETTRNQVIIISDDDDDDGDGDERSPNLQKQIKTDKIGIKREFAEEYPSTSNAILEKK
LEKEEKTKSPLLDEESDSQFFEFETPYEVFSVWQDSEPESKNSVQESESEQDSFLTSTGK
SAIDDQTNDWDYDTDYISDEVIQKVAETLEERLQSQCGVFPKEKFQIESKSKKQLSKAPM
AEDLSLCLRSVDKPHICISGDLTEEHTKNVDEKEEKESTSTLSASPNLKFEISSEESGEQ
YSPQSLSSPKLSGKPSLSKNSKKTSINPPRRQNKKMNQASPKKILCRTVPAVIPPKKFRQ
CPEPTSTAEKLGLKKGPRKAFDLSQRSLDYVVKLRDHGKTAGEVDTRQKKKTKLITPQTL
VVKNNKKMLACQDLQFLRQMRPKSHRNQQGLSATHSKDCSPKSITKPVQNSETVIQASSG
PSDNFKEKNKHASSNDKKHQRKSSFSETETVKGKSLSPVANDSPLSTKQSCTELNVRAET
NEAIVSTSKSPLSNSSSVGGDLTRVVQPLSCFHSEGTTFREADSDVNSDTEENNLFLTQY
DPVDMELSSQVESFHDFEVPVGKDTVEMEEDSKNLTGDRALSIIKCKHKDCTDIVENLDE
FCSIHSEAKVSDDCVFAKPGLPLSLSNKTVKSTTKIFSSSSNSRNAHLSRAIENSLKLPP
ASKNQTNLKATTTSKLMQPLSPLVQKPISNEGENLSNILQPQNMQTSPNYFNRPAPPSLL
EKKRTFQASSVANFPVCQSVFDSFVKEILKWKYEMFVNFDQFGPPADLCQSSLRSVPVTF
QDSQDYLNVFFPLLMLNTFETVAQEWIDNPKKENAYKLHLRSFSPGDINCGQFVVCLQEC
DMAKQLHPKENDLVFLVPKKLNGKKKAAEESEMRDQRVYHCGYVSQFRRSSVRHNSQFEG
CLSIQTQGNLSFHINESVDCIVISSLVTTQRKLKALSLLGRNSLIPLARAILNPSTSDFC
PRDSLNEAPERILAYLKEYNEDQKKAIEVAYAMVKQPPLIAKICLIHGPPGTGKSKTIVG
LLYRILTEKPRKGDSDENLNAKIKRNRVLVCAPSNAAVDELMKKIILEFKEKCQDKKNPL
GNCGDINLVRLGPEKSINNEVLKFSLDSQVNHRMKKDFPSHVQEMHERKEHLDVKLDKLS
RQRALDRCEKGQKRSNLDEEIARISKERQQLASKIKEVRGRPQEAQSSIILESHIICCTL
STSGGLLLESAFRRQGGVPFSCVIVDEAGQSCEIETLTPFIHRCNKLVLVGDPKQLPPTV
ISLKAQEHGYDQSMMARLYKHLEEQVKQNVISRSPVLQLTVQYRMHPDICLFPSSYIYNR
TLKTNRLTEESRCTSDWPFQPYLVFDVGDGSERRENDSYVNVQEIKLVMELIKLIKDKRK
DITIRNIGIITHYKAQKMMIQQELDKEFERNRPGEVDTVDAFQGRQKDCVIVTCVRANTS
QGSIGFLASLQRLNVTITRAKYSLFILGHLRTLMENEHWNHLIQDAQKRGAIIRTCGKNY
KHDAVKILKLKSVPQRNLAHPPTVVPEVIRSQNSLPSNKPEEVMNKPNSGISKTTSVASP
RHSSTSLLPADIQPFDCSEATVGTKAAEVPIVRDPRLAKRNDRDATEKFPNDAQPSSIQH
PRVTAPTYEPGLPLTHQDPNNIREHLFSEVTASSSCNLTAQLEAPSASISMRTNKRKSSE
EEGSGYRREVLSSGEEQQEKHGYKKDYHLDRDYCLDRRRKENQDSHSKRRKLS
NT seq
8262 nt
NT seq
+upstream
nt +downstream
nt
atgagtacgtgtcgctggtgtacaccaggtggtgagtccactgttgacttcctaaagagc
tatgcttttggaacacttccctgtgaagttctcacagctaatgaggacctctgttactgc
ttggagtgtgtagctgaataccacaaagcaagagatacactgccttccttgcatgagata
ttatgggaatttgaaaccactcgtctcataaatcattttgaaaaatctatgaaaggcgaa
attgaggaagatgacgaactatttatagttgatgacaatggtgaaacacaactgtttggt
ttcactggccaagacttcgaaaacaagcttcgagttcctcttcttgaaatactgaagtat
ccttatctgctcttagatgagcatgtcaatgaattatgtgttgaagcactttgtaggatg
gagcaagctaactgctcctttcaggtatttgacaaacatccagggatctatttgttcttg
gtacatcccaatgaaatggttcgacgatgggctattctaacagccagaaacttgggcaag
gtagacagagatgattactacgatttacaggaagtcttaacttgcttgtttagagttatt
gagttggggcttttagaaagtccagatatttacacttcttcagaattcgagaagggcaaa
cttgtccttctgccatctcacatgtatgacacaagtaactacaaaaattactggttagga
atctgtatgttgctaactattcttgaggagcaagcaatggattctttgttgctgggctca
gacaagcaaaatgattttatgcagtcaatacttcacaccatggaaaagcaatcagatgag
gatagtgtggatcctttctggccagcattgcattgcttcatggtgattctggatcgcctt
ggctcaaaagtctggggtcaacttattgatcccattgaagcattccagaccattattaac
aatgtgagctacaacaaagaaattcaaaatatacgcaatagttccacaaggacgaagtta
gagcctgagtcagatttggaggaaatggtgacttgcagccagattgtgtacaattataat
cccgaaaagaccaaaaaggattcaggatggagatcagctatttgccctgattactgcccc
aacatgtatgaagaaatggaaacattagccagtgtgcttcagtctgatattggacaagac
atgcgtgttcataatagcacatttctttggtttataccttttgttcagtccctcatggat
ctcaaggatttgggtgtagcttacatagtagaggttattcatcatctgtattcagaagtc
aaagatgtcctcaaccaaaaagtagcagtatgtgacacagtcactgagtttttccttctg
atattggtgtcagtaattgaactgcatagaaataagaactgtttgcatttgctgtgggtt
agttctcagcagtgggtagaagcagtagtgaaatgtgctaaacttcctaccacagcattt
gcacggagtgctgaaaagacatctggaagctactccaaaggagcaactgttatatcttct
atgcctttgcactcaattccatctaattctgtacagcttgcttgtgtgcagctgatccga
agtcttcttagggaaggttgccagcttggacagcaaactctttgtaaacaattcttagac
aaactcaacttgtgtctgaggggaaatttgtcccttggttggcatttaaatagtcaggag
accctagaattacaaacatgtttgaaacaaatcattaaaagcaaaaaagtcagaggatta
ccatgtagcacttttgtggataggaccataacatgtaaaaacccctctgtaatttacact
aaagaagaaagtgatacaactatggagaaatcaaaaaaggatacatgttctcaggacagt
tctagtccatcattttctaaagaaccaccgagagctgatgtctgtcaaggacaagagagt
ccatctctaagaagaaattacagttgggaggaggaaaataggcaaacatacttaaaggag
tcaaaactagatgaccatttttcaaataaatcatgctcaaagcaggaaaaaaaccctgat
gctaacagatctcataatcatgaaattttagataatgtagaaaaacagaagtgtactgaa
gagaacagctccacaaatatacaacagaatttggcttcagaaaataatggagtggaagga
ggatatgacagaacagcaaattttcaggcatgtttgatgacaactgactctagatctgat
tctcctcaaaatgaatcaagctcaagtgatgattcccgttcaaagaatgattctggcttt
aggaactcaaagtttaggagtaaagcacagaaagatgaattatgtgcaaaattattacag
gtaatgaaggaacacaaaaaaaccaccatggtcgccagcgttaacaatttagaatcaaag
cagagttcaaccaatttggagagtcataattcatgcaaagatgtggatgttcagaaaggg
tttgccttaatacagaaaacacagacagagccttgtattattccagaggaaacaacaaat
gaagagcaagaatcaagaaatggttattcattggttgaaaagaaaaagtcagatgataga
cagctagatcccttaacatttcataaaaaagataacctaccacaggaaagtgatagtgat
gaagatgatgatgatatggtttcacttaaaacaattagaaacaccttattgaaaaagaaa
tgtcagcttatacatcatacagataggcatgaatcaaaggacagtaattgtgaggaaact
aataatgataatgattatgttccacataatttgacaagagaagaagtgcctcctcagaac
tttaaatttaataccttaacagattctgaagtagacaaagaccttgatattcctttcata
gtccataccagtgttcttaatttcccttcagattcaactcaagaaaattcttaccagcta
cggagaaaagtgaaaaatgttaggagtctttctgtagttaacgaaattactgaattaacc
tctgttgtggagaccaccagaaatcaagttataatcatttcagatgatgatgatgatgat
ggtgatggtgatgaaagatcaccaaatcttcagaaacaaattaaaacagataaaataggc
attaagagagaatttgcagaagagtatccttcaacttctaatgccattttggaaaagaaa
ctagaaaaagaagagaaaacaaaatcccctttacttgatgaggaatctgactcacagttt
tttgaatttgaaactccatatgaagtattttctgtttggcaagattctgaaccggagagc
aaaaattctgttcaggaaagtgaatcagaacaagattcttttttgacttcaacaggtaag
agtgccatagatgatcagacaaatgattgggattatgatactgattatatatctgatgaa
gttattcaaaaggtagcagaaactcttgaagaacgtttacagtcacagtgcggtgttttt
cccaaggagaaatttcaaattgaatcaaagagtaagaaacagctatctaaagcacctatg
gctgaagatctttcattatgtttaagaagtgtagacaaacctcatatttgtatttctggg
gatcttactgaagagcacactaaaaatgtagatgagaaggaggagaaagaatctacatcc
actctttcagcatcacctaatttaaaatttgaaatttcctctgaagagtcaggtgaacag
tattctcctcagtctctttccagtccaaaacttagcggaaaaccatcactttctaaaaat
tcaaagaaaaccagtattaatcccccaagaaggcaaaacaaaaaaatgaatcaagctagt
cccaaaaagatactttgtagaacagtgcctgctgtgattcctccaaagaaatttcgccag
tgtcctgaaccaacttcaactgctgaaaaactgggtttgaaaaaggggcctcgaaaagca
tttgatttgtcccagcgatctttagattacgtagtgaagttacgtgaccatggaaaaact
gcaggtgaagttgatactcggcaaaagaagaagacaaagttaattactcctcagactctg
gttgtcaaaaataacaagaaaatgttggcatgtcaggatcttcagtttttaagacagatg
agacccaagtcccacagaaaccaacaaggactttctgccactcacagtaaagactgttct
ccaaagtcaattacaaaaccagtccagaattctgaaactgttattcaagcatcttctgga
cccagtgacaattttaaagaaaaaaacaagcatgcctcaagcaatgataaaaagcatcaa
agaaaaagctcattttctgagacagaaacagttaaaggaaaaagtctatcaccggttgct
aatgacagtcctctttctaccaaacaaagttgtacagaattaaatgttagagcagaaaca
aatgaagccattgtttctacttcaaagagccctttgtctaactcatcttctgttggaggt
gacctaacaagggttgtccaacccttatcttgttttcattctgagggaacaacttttaga
gaggcagactctgatgttaacagtgatacagaggaaaataatttgtttttaacacaatat
gatcctgtagatatggaattaagttcacaggtagagagttttcatgactttgaagttcct
gttggaaaagatacagtagaaatggaggaagattctaaaaaccttactggggacagggct
ttgagtattataaagtgtaagcacaaagattgtactgacattgtggaaaatctggatgaa
ttttgctctatacattctgaagctaaagtgtctgatgactgtgtttttgctaaaccaggc
ttaccactttcactgtcaaacaaaactgtaaagtctactactaagatttttagttcaagt
agtaattcacgaaatgctcatctttctagagctatagaaaatagtttaaaactcccacca
gcttcaaaaaatcaaacaaatttgaaagccacaactacgtcaaaattaatgcaaccactt
tctccattagttcaaaagccaatttcgaatgagggggaaaatttgtctaacattcttcaa
ccacagaatatgcagacttctccaaattacttcaacagacctgctccaccaagtctcctt
gagaagaaaagaacttttcaagcttcctctgttgcaaattttcctgtgtgtcaatctgta
tttgacagctttgttaaggagattttaaaatggaagtatgaaatgtttgtaaattttgat
cagtttgggcctccagcagatctttgccagtcgtccttaagatctgttcctgtcacattt
caggactctcaagactatctaaatgtttttttccctttgctgatgttgaatacttttgaa
acagtggcccaagaatggattgacaacccaaagaaagagaatgcctataagctccattta
cgaagcttttctcctggtgacataaattgtgggcagtttgtggtttgtcttcaggagtgt
gatatggctaaacaactacatccaaaggaaaatgacttggtatttttggttcctaaaaaa
ttaaatggaaaaaaaaaagctgcagaagaaagtgagatgagagatcagcgagtgtatcat
tgtggttatgtatctcagtttcgacgctcttcagtcagacataattcacaatttgagggt
tgcctttccatccagactcaaggcaatttgtcattccacataaatgaatcagtagactgt
attgtgatcagttctttggtgactacgcaacggaagttgaaagccttgtctcttttgggg
aggaattcactgattccactggccagggcaattctgaacccaagtacttcagacttttgt
cctcgagattcactgaacgaggctcctgagaggattcttgcctacctgaaagaatataat
gaagatcagaaaaaagcaattgaagttgcatatgccatggtaaagcaaccaccgttaatt
gccaaaatctgtctgattcatggaccccctggaactggcaaatcaaaaactattgttggc
ctattatatcgtattctgacagagaaaccaaggaaaggagattcagatgaaaacttgaat
gccaaaatcaaacgaaatcgtgttcttgtatgtgcaccctctaatgcagctgttgatgaa
cttatgaaaaaaatcatccttgaatttaaagaaaaatgccaagacaagaagaatcccttg
ggaaattgtggagatataaatttagtgcgactgggtccagaaaaatctattaataatgaa
gtcctaaaattcagcttggatagccaagttaaccacagaatgaaaaaggactttcccagt
catgttcaagagatgcatgagagaaaggaacatctggatgttaaattagacaagctttct
cgccagcgtgctttggatcgatgtgaaaaggggcagaagagatcaaatttagatgaggaa
attgcccgaatttccaaagaaaggcagcagctcgcttctaaaattaaagaggttcgagga
cggccacaggaagctcagagcagcattatcctggagtcccatatcatttgctgtacactg
agcacaagtggtggtttgctgttggagtctgcttttcgtaggcaaggaggtgttcccttc
agttgtgtcattgttgatgaggctgggcagtcttgtgagattgagacacttactccattt
atccatcgctgcaacaaacttgttctggttggagatcctaaacagcttcctcccacggtc
atttctctgaaagcacaggagcatggttatgaccagtcaatgatggctcgattatacaaa
cacctggaagaacaggtgaaacagaatgtgatcagtagatcacctgttttgcagctgaca
gttcaatacaggatgcatcctgatatatgcctcttcccatctagttatatttataacaga
actttgaaaacaaacagattgactgaagagagccgatgtacatccgactggccgttccag
ccttaccttgtgtttgatgtaggagatggttcagagagacgggaaaatgactcctatgtt
aatgtccaagaaataaaactagtaatggaattaattaagctgatcaaagacaaaagaaag
gatattactatacgtaacatcggtataatcacacattacaaagcacaaaagatgatgatt
caacaggaattggacaaagaatttgaaagaaacagaccaggggaagttgacactgtggat
gcattccagggtcgtcagaaggattgtgttattgttacatgtgtcagagcaaatacttca
caaggctcaattgggtttctggcaagtttgcaaagattgaatgtaaccattactcgagcc
aaatatagtctgtttatccttggacatttgaggacattaatggaaaatgaacattggaat
cacctaattcaagatgctcagaaacgaggtgccattattaggacctgtggcaagaattat
aagcatgatgcagtgaaaattttgaaactcaaatctgtgccacagcgaaacctagcacac
cctcccactgtagtgccagaagtcattagatcccagaatagtttacccagcaataagcca
gaagaagtgatgaacaaacctaacagtggtatttctaagaccacttctgttgcttctcca
cggcacagcagcacttccttgttacctgctgacattcagccctttgactgcagcgaagct
acagttggtacaaaagctgctgaagtacctattgtccgggacccaagactagccaagaga
aatgatcgtgatgccactgagaagttcccaaatgatgcacaaccatccagtatccagcat
ccaagagtgacagcacctacatatgaacctggccttcctttaactcaccaggaccccaat
aatatcagagagcaccttttttcagaagtaacagcttccagcagttgcaacctgacagca
caacttgaagctccctctgcaagtatctccatgcgcacaaacaaaagaaaatccagtgaa
gaggaaggatctggctacagaagagaagtgttatcttccggagaagaacaacaagaaaag
catgggtataagaaagactatcatttagacagggactattgcttggataggaggagaaaa
gaaaaccaggacagtcattcaaaaagaagaaaactttcatag
DBGET
integrated database retrieval system
