Phascolarctos cinereus (koala): 110202309 Help Entry 110202309         CDS       T05867                                  Name (RefSeq) GTPase HRas-like   KO K07828   GTPase NRas Organism pcw  Phascolarctos cinereus (koala) Pathway pcw01521   EGFR tyrosine kinase inhibitor resistance pcw01522   Endocrine resistance pcw04010   MAPK signaling pathway pcw04012   ErbB signaling pathway pcw04014   Ras signaling pathway pcw04015   Rap1 signaling pathway pcw04062   Chemokine signaling pathway pcw04068   FoxO signaling pathway pcw04071   Sphingolipid signaling pathway pcw04072   Phospholipase D signaling pathway pcw04137   Mitophagy - animal pcw04140   Autophagy - animal pcw04150   mTOR signaling pathway pcw04151   PI3K-Akt signaling pathway pcw04210   Apoptosis pcw04211   Longevity regulating pathway pcw04213   Longevity regulating pathway - multiple species pcw04218   Cellular senescence pcw04360   Axon guidance pcw04370   VEGF signaling pathway pcw04371   Apelin signaling pathway pcw04540   Gap junction pcw04550   Signaling pathways regulating pluripotency of stem cells pcw04625   C-type lectin receptor signaling pathway pcw04650   Natural killer cell mediated cytotoxicity pcw04660   T cell receptor signaling pathway pcw04662   B cell receptor signaling pathway pcw04664   Fc epsilon RI signaling pathway pcw04714   Thermogenesis pcw04720   Long-term potentiation pcw04722   Neurotrophin signaling pathway pcw04725   Cholinergic synapse pcw04726   Serotonergic synapse pcw04730   Long-term depression pcw04810   Regulation of actin cytoskeleton pcw04910   Insulin signaling pathway pcw04912   GnRH signaling pathway pcw04915   Estrogen signaling pathway pcw04916   Melanogenesis pcw04917   Prolactin signaling pathway pcw04919   Thyroid hormone signaling pathway pcw04921   Oxytocin signaling pathway pcw04926   Relaxin signaling pathway pcw04929   GnRH secretion pcw04933   AGE-RAGE signaling pathway in diabetic complications pcw04935   Growth hormone synthesis, secretion and action pcw05010   Alzheimer disease pcw05022   Pathways of neurodegeneration - multiple diseases pcw05034   Alcoholism pcw05160   Hepatitis C pcw05161   Hepatitis B pcw05163   Human cytomegalovirus infection pcw05165   Human papillomavirus infection pcw05166   Human T-cell leukemia virus 1 infection pcw05167   Kaposi sarcoma-associated herpesvirus infection pcw05170   Human immunodeficiency virus 1 infection pcw05200   Pathways in cancer pcw05203   Viral carcinogenesis pcw05205   Proteoglycans in cancer pcw05206   MicroRNAs in cancer pcw05207   Chemical carcinogenesis - receptor activation pcw05208   Chemical carcinogenesis - reactive oxygen species pcw05210   Colorectal cancer pcw05211   Renal cell carcinoma pcw05213   Endometrial cancer pcw05214   Glioma pcw05215   Prostate cancer pcw05216   Thyroid cancer pcw05218   Melanoma pcw05219   Bladder cancer pcw05220   Chronic myeloid leukemia pcw05221   Acute myeloid leukemia pcw05223   Non-small cell lung cancer pcw05224   Breast cancer pcw05225   Hepatocellular carcinoma pcw05226   Gastric cancer pcw05230   Central carbon metabolism in cancer pcw05231   Choline metabolism in cancer pcw05235   PD-L1 expression and PD-1 checkpoint pathway in cancer pcw05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:pcw00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     110202309    04012 ErbB signaling pathway     110202309    04014 Ras signaling pathway     110202309    04015 Rap1 signaling pathway     110202309    04370 VEGF signaling pathway     110202309    04371 Apelin signaling pathway     110202309    04068 FoxO signaling pathway     110202309    04072 Phospholipase D signaling pathway     110202309    04071 Sphingolipid signaling pathway     110202309    04151 PI3K-Akt signaling pathway     110202309    04150 mTOR signaling pathway     110202309  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     110202309    04137 Mitophagy - animal     110202309   09143 Cell growth and death    04210 Apoptosis     110202309    04218 Cellular senescence     110202309   09144 Cellular community - eukaryotes    04540 Gap junction     110202309    04550 Signaling pathways regulating pluripotency of stem cells     110202309   09142 Cell motility    04810 Regulation of actin cytoskeleton     110202309  09150 Organismal Systems   09151 Immune system    04625 C-type lectin receptor signaling pathway     110202309    04650 Natural killer cell mediated cytotoxicity     110202309    04660 T cell receptor signaling pathway     110202309    04662 B cell receptor signaling pathway     110202309    04664 Fc epsilon RI signaling pathway     110202309    04062 Chemokine signaling pathway     110202309   09152 Endocrine system    04910 Insulin signaling pathway     110202309    04929 GnRH secretion     110202309    04912 GnRH signaling pathway     110202309    04915 Estrogen signaling pathway     110202309    04917 Prolactin signaling pathway     110202309    04921 Oxytocin signaling pathway     110202309    04926 Relaxin signaling pathway     110202309    04935 Growth hormone synthesis, secretion and action     110202309    04919 Thyroid hormone signaling pathway     110202309    04916 Melanogenesis     110202309   09156 Nervous system    04725 Cholinergic synapse     110202309    04726 Serotonergic synapse     110202309    04720 Long-term potentiation     110202309    04730 Long-term depression     110202309    04722 Neurotrophin signaling pathway     110202309   09158 Development and regeneration    04360 Axon guidance     110202309   09149 Aging    04211 Longevity regulating pathway     110202309    04213 Longevity regulating pathway - multiple species     110202309   09159 Environmental adaptation    04714 Thermogenesis     110202309  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     110202309    05206 MicroRNAs in cancer     110202309    05205 Proteoglycans in cancer     110202309    05207 Chemical carcinogenesis - receptor activation     110202309    05208 Chemical carcinogenesis - reactive oxygen species     110202309    05203 Viral carcinogenesis     110202309    05230 Central carbon metabolism in cancer     110202309    05231 Choline metabolism in cancer     110202309    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     110202309   09162 Cancer: specific types    05210 Colorectal cancer     110202309    05225 Hepatocellular carcinoma     110202309    05226 Gastric cancer     110202309    05214 Glioma     110202309    05216 Thyroid cancer     110202309    05221 Acute myeloid leukemia     110202309    05220 Chronic myeloid leukemia     110202309    05218 Melanoma     110202309    05211 Renal cell carcinoma     110202309    05219 Bladder cancer     110202309    05215 Prostate cancer     110202309    05213 Endometrial cancer     110202309    05224 Breast cancer     110202309    05223 Non-small cell lung cancer     110202309   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     110202309    05170 Human immunodeficiency virus 1 infection     110202309    05161 Hepatitis B     110202309    05160 Hepatitis C     110202309    05163 Human cytomegalovirus infection     110202309    05167 Kaposi sarcoma-associated herpesvirus infection     110202309    05165 Human papillomavirus infection     110202309   09164 Neurodegenerative disease    05010 Alzheimer disease     110202309    05022 Pathways of neurodegeneration - multiple diseases     110202309   09165 Substance dependence    05034 Alcoholism     110202309   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     110202309   09167 Endocrine and metabolic disease    04933 AGE-RAGE signaling pathway in diabetic complications     110202309   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     110202309    01522 Endocrine resistance     110202309  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:pcw04131]     110202309   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:pcw04147]     110202309    04031 GTP-binding proteins [BR:pcw04031]     110202309 Membrane trafficking [BR:pcw04131]  Exocytosis   Small GTPases and associated proteins    Other small GTPases and associated proteins     110202309  Endocytosis   Macropinocytosis    Ras GTPases     110202309 Exosome [BR:pcw04147]  Exosomal proteins   Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)    110202309   Exosomal proteins of other body fluids (saliva and urine)    110202309   Exosomal proteins of breast cancer cells    110202309   Exosomal proteins of colorectal cancer cells    110202309 GTP-binding proteins [BR:pcw04031]  Small (monomeric) G-proteins   Ras Family    Ras [OT]     110202309 BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Ras Roc MMR_HSR1 Motif Other DBs NCBI-GeneID:  110202309 NCBI-ProteinID:  XP_020833990 UniProt:  A0A6P5JID3 LinkDB All DBs Position Unknown AA seq 169 aa AA seqDB search MYKLVVMGSCGVGKSVLSIHFLQNRFVAEYEPTARDLYHGVAVVDREPCELDILAMAGDE KYFEQGEDLGEGFLCIYTIDYIKTFVEVNFFQDQLQKVKGTTLVPMVLMANKINEAHWLV DLDMGSGSGQKPQVALCESLGQDLGMEHTFKELVREILQMHTEEKLKGH NT seq 510 nt NT seq  +upstreamnt  +downstreamnt atgtacaaactggtggtgatgggaagctgtggtgtgggcaagagtgtgctgagcatccat ttccttcagaaccgctttgtggctgagtatgagcccacagctagagacttgtaccatggt gtggcagtggtggacagggagccctgtgagctggatatcctggccatggcaggagatgag aagtactttgagcagggtgaggacttgggagaaggcttcctctgcatctacactattgac tacattaagacctttgtggaagtgaatttcttccaagaccagctacaaaaggtcaagggc accaccctggtgcccatggtgctgatggccaacaaaatcaatgaggcccactggctggta gacttggacatgggttcgggaagtgggcaaaagcctcaggttgccctttgtgaaagcctt ggccaagacctcggcatggagcacaccttcaaagaactggttcgagagatccttcagatg cacactgaggagaagctcaagggccactag

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