Phascolarctos cinereus (koala): 110202383
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Entry
110202383 CDS
T05867
Symbol
BCKDHA
Name
(RefSeq) 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial isoform X1
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
pcw
Phascolarctos cinereus (koala)
Pathway
pcw00280
Valine, leucine and isoleucine degradation
pcw00640
Propanoate metabolism
pcw00785
Lipoic acid metabolism
pcw01100
Metabolic pathways
pcw01210
2-Oxocarboxylic acid metabolism
Module
pcw_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
pcw00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
110202383 (BCKDHA)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
110202383 (BCKDHA)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
110202383 (BCKDHA)
Enzymes [BR:
pcw01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
110202383 (BCKDHA)
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Motif
Pfam:
E1_dh
TPP_enzyme_C
DXP_synthase_N
Motif
Other DBs
NCBI-GeneID:
110202383
NCBI-ProteinID:
XP_020834117
UniProt:
A0A6P5JIP2
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All DBs
Position
Unknown
AA seq
591 aa
AA seq
DB search
MVSTDFNLPPHVLPELWERAREPRSQRACAKSLFVKARCHAFPQSRPQLRPEEIIRSPGE
RRRDQNGPKSYPSPGGPRSRGWPRFRLKAQPPQRPRGSGRRGLPPWRAVSGGLGGSAGSR
GAVGVDSFSGDGLAGPGEKLGGSRGARRLTAPVKMAAAAARAWGLRGGLALAQRGPRGLA
GSATRWQQEDFSSLDEKPQFPGASAEFVDKLDFIKPNVISGIPVYRVMDRQGQIINASED
PQLPQEVVLKLYKSMTLLNTMDRILYESQRQGRISFYMTNYGEEGTHVGSAAALDDTDLV
FGQYREAGVLMYRGYPLNLFMSQCYGNSGDPSKGRQMPVHYGCKERNFVTISSPLATQIP
QAVGAAYAAKRANSNQAVICYFGEGAASEGDAHAGFNFAATLECPIIFFCRNNGYAISTP
TSEQYRGDGIAARGPGYGIMSIRVDGNDVFAVYNATREARRRAVAENQPFLIEAMTYRIG
HHSTSDDSSAYRSVDEVNYWDKQDHPISRLRHYMLSRGWWDEEQEKGWRKQSRKKVMEAF
EEAERKLKPPVGLLFSDVYQEMPARLQKQQEALSRHLQAYGEHYPLDHFEQ
NT seq
1776 nt
NT seq
+upstream
nt +downstream
nt
atggtttccactgatttcaacctccctccccacgtcctgcctgagctgtgggagagggcg
cgggagccacgatcacaacgcgcttgcgcgaagagtttgtttgtaaaggctagatgccac
gctttccctcagtcccgcccccaacttaggccagaggaaattattaggtcgcctggagag
aggaggcgggatcaaaatggcccgaagtcctatcccagccccggaggaccccggtcaagg
ggctggcctcgcttccgcctgaaggcgcagccgcctcagaggccgagggggagtggcaga
cgggggctgcctccctggcgggcagtgtccggaggcttgggaggcagtgctggctcacgt
ggggccgtgggcgtggacagcttttcaggcgatggacttgccggccccggagagaagctg
ggtggaagtcgcggagcgagacggttaacggctccagtcaaaatggcggcggcagcggca
cgagcctggggcctgcgaggggggctggccttagcccagcgcgggcctcgcggattggcg
ggatccgccacccggtggcagcaggaagatttctcatccctggatgaaaaaccccagttc
cctggtgcctctgccgagtttgtggataagctagatttcattaaacccaatgtcatttct
ggcatccctgtctaccgggtgatggaccgccagggacagatcatcaatgccagcgaggac
ccccagctgcctcaggaggtggtcctgaagctatacaaaagcatgactcttctcaacacc
atggacagaatcctctatgagtctcagaggcagggccggatctccttctacatgaccaac
tatggggaggagggcacccacgtgggcagtgcagccgccctggacgacacagacctggtg
tttgggcagtaccgggaggcaggagtgctgatgtaccgtggctacccattgaatctgttc
atgtcccagtgctacggcaactcgggtgaccccagcaaggggcgccagatgcccgtccac
tatggctgcaaggaaaggaactttgtcaccatctcctcccccctggccacgcagatcccc
caggcggtgggagcagcctatgcagccaagagggccaattccaaccaggccgtgatctgc
tactttggggagggggcagccagcgagggcgatgcccatgctggcttcaactttgctgcc
accttggagtgccccatcatcttcttctgccgcaacaacggctacgccatctccactccc
acctcggagcagtatcggggtgatggcatcgcggcccgaggccccggctacggcatcatg
tccatacgagtggacggcaatgacgtgtttgcagtgtacaatgccaccagagaggcccgg
cggcgggcagtggccgagaaccagcccttcctcattgaggccatgacctacaggatcggg
caccatagcaccagtgatgacagttcggcctatcgctccgtggacgaggtcaattactgg
gacaagcaagaccaccccatctcccggctgcgccattacatgctgagccgtggatggtgg
gatgaggagcaggagaagggctggcggaagcagtctaggaagaaggtgatggaggccttc
gaagaggcagaaagaaagctgaagcccccggttggcctcctcttctctgatgtgtaccaa
gagatgccggcccggctccagaaacagcaggaagccctgagccgccacctgcaggcctac
ggcgagcactacccactggaccatttcgagcagtga
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