KEGG   Phascolarctos cinereus (koala): 110205152
Entry
110205152         CDS       T05867                                 
Symbol
GNAS
Name
(RefSeq) guanine nucleotide-binding protein G(s) subunit alpha
  KO
K04632  guanine nucleotide-binding protein G(s) subunit alpha
Organism
pcw  Phascolarctos cinereus (koala)
Pathway
pcw01522  Endocrine resistance
pcw04015  Rap1 signaling pathway
pcw04020  Calcium signaling pathway
pcw04024  cAMP signaling pathway
pcw04072  Phospholipase D signaling pathway
pcw04081  Hormone signaling
pcw04082  Neuroactive ligand signaling
pcw04261  Adrenergic signaling in cardiomyocytes
pcw04270  Vascular smooth muscle contraction
pcw04540  Gap junction
pcw04611  Platelet activation
pcw04713  Circadian entrainment
pcw04714  Thermogenesis
pcw04724  Glutamatergic synapse
pcw04726  Serotonergic synapse
pcw04728  Dopaminergic synapse
pcw04730  Long-term depression
pcw04750  Inflammatory mediator regulation of TRP channels
pcw04911  Insulin secretion
pcw04912  GnRH signaling pathway
pcw04913  Ovarian steroidogenesis
pcw04915  Estrogen signaling pathway
pcw04916  Melanogenesis
pcw04918  Thyroid hormone synthesis
pcw04921  Oxytocin signaling pathway
pcw04922  Glucagon signaling pathway
pcw04923  Regulation of lipolysis in adipocytes
pcw04924  Renin secretion
pcw04925  Aldosterone synthesis and secretion
pcw04926  Relaxin signaling pathway
pcw04927  Cortisol synthesis and secretion
pcw04928  Parathyroid hormone synthesis, secretion and action
pcw04934  Cushing syndrome
pcw04935  Growth hormone synthesis, secretion and action
pcw04961  Endocrine and other factor-regulated calcium reabsorption
pcw04962  Vasopressin-regulated water reabsorption
pcw04970  Salivary secretion
pcw04971  Gastric acid secretion
pcw04972  Pancreatic secretion
pcw04976  Bile secretion
pcw05012  Parkinson disease
pcw05030  Cocaine addiction
pcw05031  Amphetamine addiction
pcw05032  Morphine addiction
pcw05034  Alcoholism
pcw05142  Chagas disease
pcw05146  Amoebiasis
pcw05163  Human cytomegalovirus infection
pcw05165  Human papillomavirus infection
pcw05200  Pathways in cancer
pcw05207  Chemical carcinogenesis - receptor activation
pcw05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:pcw00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    110205152 (GNAS)
   04020 Calcium signaling pathway
    110205152 (GNAS)
   04072 Phospholipase D signaling pathway
    110205152 (GNAS)
   04024 cAMP signaling pathway
    110205152 (GNAS)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    110205152 (GNAS)
   04081 Hormone signaling
    110205152 (GNAS)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    110205152 (GNAS)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    110205152 (GNAS)
  09152 Endocrine system
   04911 Insulin secretion
    110205152 (GNAS)
   04922 Glucagon signaling pathway
    110205152 (GNAS)
   04923 Regulation of lipolysis in adipocytes
    110205152 (GNAS)
   04912 GnRH signaling pathway
    110205152 (GNAS)
   04913 Ovarian steroidogenesis
    110205152 (GNAS)
   04915 Estrogen signaling pathway
    110205152 (GNAS)
   04921 Oxytocin signaling pathway
    110205152 (GNAS)
   04926 Relaxin signaling pathway
    110205152 (GNAS)
   04935 Growth hormone synthesis, secretion and action
    110205152 (GNAS)
   04918 Thyroid hormone synthesis
    110205152 (GNAS)
   04928 Parathyroid hormone synthesis, secretion and action
    110205152 (GNAS)
   04916 Melanogenesis
    110205152 (GNAS)
   04924 Renin secretion
    110205152 (GNAS)
   04925 Aldosterone synthesis and secretion
    110205152 (GNAS)
   04927 Cortisol synthesis and secretion
    110205152 (GNAS)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    110205152 (GNAS)
   04270 Vascular smooth muscle contraction
    110205152 (GNAS)
  09154 Digestive system
   04970 Salivary secretion
    110205152 (GNAS)
   04971 Gastric acid secretion
    110205152 (GNAS)
   04972 Pancreatic secretion
    110205152 (GNAS)
   04976 Bile secretion
    110205152 (GNAS)
  09155 Excretory system
   04962 Vasopressin-regulated water reabsorption
    110205152 (GNAS)
   04961 Endocrine and other factor-regulated calcium reabsorption
    110205152 (GNAS)
  09156 Nervous system
   04724 Glutamatergic synapse
    110205152 (GNAS)
   04728 Dopaminergic synapse
    110205152 (GNAS)
   04726 Serotonergic synapse
    110205152 (GNAS)
   04730 Long-term depression
    110205152 (GNAS)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    110205152 (GNAS)
  09159 Environmental adaptation
   04713 Circadian entrainment
    110205152 (GNAS)
   04714 Thermogenesis
    110205152 (GNAS)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    110205152 (GNAS)
   05207 Chemical carcinogenesis - receptor activation
    110205152 (GNAS)
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    110205152 (GNAS)
   05165 Human papillomavirus infection
    110205152 (GNAS)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    110205152 (GNAS)
   05142 Chagas disease
    110205152 (GNAS)
  09164 Neurodegenerative disease
   05012 Parkinson disease
    110205152 (GNAS)
  09165 Substance dependence
   05030 Cocaine addiction
    110205152 (GNAS)
   05031 Amphetamine addiction
    110205152 (GNAS)
   05032 Morphine addiction
    110205152 (GNAS)
   05034 Alcoholism
    110205152 (GNAS)
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy
    110205152 (GNAS)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    110205152 (GNAS)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    110205152 (GNAS)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:pcw04147]
    110205152 (GNAS)
   04031 GTP-binding proteins [BR:pcw04031]
    110205152 (GNAS)
Exosome [BR:pcw04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   110205152 (GNAS)
  Exosomal proteins of other body fluids (saliva and urine)
   110205152 (GNAS)
  Exosomal proteins of colorectal cancer cells
   110205152 (GNAS)
  Exosomal proteins of bladder cancer cells
   110205152 (GNAS)
GTP-binding proteins [BR:pcw04031]
 Heterotrimeric G-proteins
  Alpha Subunits
   Alpha type 2 (Gs)
    110205152 (GNAS)
SSDB
Motif
Pfam: G-alpha Arf Roc Gtr1_RagA GTP_EFTU AAA_14 TniB AAA_29
Other DBs
NCBI-GeneID: 110205152
NCBI-ProteinID: XP_020837128
UniProt: A0A6P5JUL8
LinkDB
Position
Unknown
AA seq 380 aa
MGCLGNSKTEDQRNEEKAQREANKKIEKQLQKDKQVYRATHRLLLLGAGESGKSTIVKQM
RILHVNGFNADTEKKMKIQDIKNNIKEAIETIVTAMGNLAPPVELANPENQFRIDYILNL
ANQIDFDFPPEFYEHTKTLWQDEGVKACYERSNEYQLIDCAQYFLDKIDVVKQNEYTPSD
QDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVASSSYN
MVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIEDYFPE
FARYTTPDDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYPHFTCAVDTENIRR
VFNDCRDIIQRMHLRQYELL
NT seq 1143 nt   +upstreamnt  +downstreamnt
atggggtgcctggggaacagcaagacggaagatcagcggaacgaggagaaggcgcagcga
gaggccaacaagaagatcgagaagcagctgcagaaggacaagcaggtctaccgggccacc
caccgcctcctgctgctgggtgctggtgaatctggtaaaagcacaattgtaaaacagatg
aggatcttgcacgtcaatggatttaatgctgacacagagaaaaaaatgaaaattcaagat
attaaaaataatattaaagaagctatagagacaatagtgacagcaatgggaaatttggca
cctccagttgagctagccaatccagagaatcagtttcgaattgactacattttaaactta
gctaaccagatagactttgacttcccaccagaattttatgaacatactaaaacactttgg
caagatgaaggtgtgaaagcctgctacgagagatctaatgaatatcagttgattgattgt
gctcagtactttctagacaagattgacgtagtcaaacaaaatgaatatacaccatctgac
caagatctcctcagatgcagagtattgacatcaggaatttttgaaaccaaatttcaagtg
gataaagtaaattttcacatgtttgatgtcggaggacagcgagatgaacgtagaaaatgg
atccagtgttttaatgatgtgactgctataatatttgtggtggccagcagtagctacaac
atggttatacgagaggacaatcagaccaatcggcttcaagaagcactaaatctcttcaag
agcatctggaacaacaggtggctacggaccatttcagtaattctattcctgaataaacag
gatttattagcagagaaagttttggcagggaaatctaaaattgaggactactttccagaa
tttgctcgctacactacaccagatgatgcaacacctgagcctggtgaggatcccagagtt
acaagggccaagtattttattagggatgaatttcttagaatcagtacagcaagtggagat
ggacggcactactgctacccccactttacatgtgcagtggatacagaaaacatcagaagg
gttttcaatgactgtcgggacattattcaacggatgcaccttcgtcaatatgagttattg
tga

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