Phascolarctos cinereus (koala): 110206059
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Entry
110206059 CDS
T05867
Symbol
HMGCL
Name
(RefSeq) hydroxymethylglutaryl-CoA lyase, mitochondrial isoform X1
KO
K01640
hydroxymethylglutaryl-CoA lyase [EC:
4.1.3.4
]
Organism
pcw
Phascolarctos cinereus (koala)
Pathway
pcw00280
Valine, leucine and isoleucine degradation
pcw00650
Butanoate metabolism
pcw01100
Metabolic pathways
pcw04146
Peroxisome
Module
pcw_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
pcw00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00650 Butanoate metabolism
110206059 (HMGCL)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
110206059 (HMGCL)
09140 Cellular Processes
09141 Transport and catabolism
04146 Peroxisome
110206059 (HMGCL)
Enzymes [BR:
pcw01000
]
4. Lyases
4.1 Carbon-carbon lyases
4.1.3 Oxo-acid-lyases
4.1.3.4 hydroxymethylglutaryl-CoA lyase
110206059 (HMGCL)
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Ortholog
Paralog
GFIT
Motif
Pfam:
HMGL-like
Motif
Other DBs
NCBI-GeneID:
110206059
NCBI-ProteinID:
XP_020838736
UniProt:
A0A6P5K1B6
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All DBs
Position
Unknown
AA seq
328 aa
AA seq
DB search
MRPFWRSLGLPRMVGVSSLRAISSFSLPALPKKVKIVEVGPRDGLQNEKSIVPAQLKIRL
IDMLSESGLPVIEATSFVSPKWVPQMADHAEVLKGIRKLPGIRYPVLTPNLTGFQAAVSS
GAEEVAIFGAASELFTKKNINCSIDESLERFEKVLSAARAADIPVRGYVSCVLGCPYEGK
ISPAKVAEVAKKLYSMGCYEISLGDTIGVGTLVGMKDMLSAVMKEVPVSALAVHCHDTYG
QALTNILMALQMGVTVVDSSVAGLGGCPYAKGASGNVATEDLLYMLNGLGIETGVSLPKL
LEAGKFICKALDRKSNSKVAQATFSSRL
NT seq
987 nt
NT seq
+upstream
nt +downstream
nt
atgaggccgttctggagatcgttgggattaccaaggatggtaggggtgtcttccctgcgg
gctatcagctcattcagtctacctgcactcccaaagaaggttaaaatcgtggaggtcggc
cctcgagatggtctgcaaaatgaaaagtctattgtacctgctcagttgaaaatcaggctg
atagacatgttgtctgagtcaggactccctgtcattgaggccaccagcttcgtttccccc
aagtgggtgccccagatggcagaccacgctgaagtcctgaagggcatcaggaagcttcct
ggcatccgctacccagtgctgacccccaacctcacaggcttccaggcagcggtttcttcg
ggggccgaggaagtggccatctttggggctgcttcggagctcttcaccaagaagaacatt
aactgctccatcgacgagagcctggagcgctttgagaaggtcctgagtgctgccagagcc
gccgacattcctgtgcgagggtacgtgtcctgtgtgcttggatgcccgtacgaagggaaa
atctccccagccaaagtagctgaggtggctaagaagctgtattcaatgggctgctatgag
atctcactgggtgacactattggtgtgggcaccctggttggaatgaaggatatgctgtct
gctgtcatgaaagaggtgccagtgagtgccctggccgtccattgccatgacacctatgga
caagccctcaccaacatcttaatggctcttcagatgggagtgactgtggtggattcatcg
gttgctgggcttgggggctgcccctatgctaagggtgcatcaggaaatgtggcaacagaa
gaccttctgtacatgctgaatggactgggaatcgaaacaggagtgagccttccgaagttg
ttggaagctggaaaatttatctgcaaggcgttggatagaaaaagcaattcaaaagtggcc
caggccactttcagctccaggctgtga
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