Phascolarctos cinereus (koala): 110206774
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Entry
110206774 CDS
T05867
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, mitochondrial-like
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
pcw
Phascolarctos cinereus (koala)
Pathway
pcw00010
Glycolysis / Gluconeogenesis
pcw00020
Citrate cycle (TCA cycle)
pcw00620
Pyruvate metabolism
pcw00785
Lipoic acid metabolism
pcw01100
Metabolic pathways
pcw01200
Carbon metabolism
pcw01210
2-Oxocarboxylic acid metabolism
pcw04066
HIF-1 signaling pathway
pcw04922
Glucagon signaling pathway
pcw05230
Central carbon metabolism in cancer
pcw05415
Diabetic cardiomyopathy
Module
pcw_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
pcw00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
110206774
00020 Citrate cycle (TCA cycle)
110206774
00620 Pyruvate metabolism
110206774
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
110206774
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
110206774
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
110206774
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
110206774
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
110206774
Enzymes [BR:
pcw01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
110206774
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Ortholog
Paralog
GFIT
Motif
Pfam:
E1_dh
TPP_enzyme_C
DXP_synthase_N
Motif
Other DBs
NCBI-GeneID:
110206774
NCBI-ProteinID:
XP_020839943
UniProt:
A0A6P5K3R1
LinkDB
All DBs
Position
Unknown
AA seq
476 aa
AA seq
DB search
MTVILDEELPDQQEYTASCQRETPTTPKPRQDLLLACQDRAHTAMACARPCSPVTPNESR
ATVPSVQSATGQRSPRRRRSLSGYRCLPKMLPVASRVLRSASPKPPARVLLAARTFVSEA
SFDIKKCALHRLEEGPPVQAVLTRDEGLKYYKNMQTVRRMELKADQLYKQKIIRGFCHLY
DGQEACCVGIEAAINPSDHVITAYRAHGFTYGRGLSVREILAELTGRKGGCAKGKGGSMH
MYAKNFYGGNGIVGAQVPLGAGVALACKYSGKDEVCFTLYGDGAANQGQVFETYNMAALW
KLPCIFVCENNRYGMGTSVERAAASTDYYKRGDYIPGIRVDGMDILCVREAAKFAAAHCR
SGKGPILMELQTYRYHGHSMSDPGISYRSRQEVQEVRSKSDPIMLHKERMVNSKLASVEE
LKEIDIEVRKEVEDAAQFATSDPEPPLEELGCHIYSKHPPFDVRGVNQWIKYKSVS
NT seq
1431 nt
NT seq
+upstream
nt +downstream
nt
atgacggtcatccttgatgaagagctcccagatcaacaagaatatactgcaagttgccag
agagaaacaccaacaacccccaaaccccgccaagatctgctgctggcttgccaggacagg
gcccacactgccatggcctgtgctagaccgtgctcccctgtcaccccaaacgagtctcgg
gccacggttccttctgttcaatccgccaccggccaacggtcaccccgacgccgccgctca
ctctcggggtaccgctgcctgccgaaaatgctccctgtggcttcccgcgtgctgaggagc
gcctccccaaagccaccggcaagagtgctgttggcagcccgtacctttgtaagcgaagct
tcgtttgatattaagaaatgcgcccttcatcgacttgaggagggccctcccgtccaagca
gttctcaccagagacgaaggactcaagtattacaagaacatgcagactgtccgtcggatg
gagctgaaggcagatcagctgtacaagcaaaagatcatccgtggtttctgccacttgtac
gacggtcaggaagcgtgttgtgtggggatcgaggccgctataaacccttcggatcatgtg
attacagcctatcgagctcacggctttacctatggtcgtggactttccgtccgagaaatc
ctggccgagctcacgggacgaaaagggggatgcgctaaaggcaagggagggtcgatgcac
atgtacgccaagaacttctacgggggcaacggcattgtcggggctcaggtgccgctggga
gctggcgttgctctggcctgtaagtactcgggaaaggatgaagtctgtttcactttgtac
ggagacggcgctgctaatcagggtcaggtattcgaaacttacaatatggcagctttgtgg
aagttgccttgtatttttgtttgtgagaataatcgatacggaatgggaacttctgtagag
agagcagcagccagcaccgactattacaaaagaggagactatattccaggaataagggtt
gatggtatggacattttgtgtgtccgtgaggcagcgaaatttgcagctgcccactgcaga
tcgggaaagggccccatactgatggaactacagacatatcgttatcatggacacagcatg
agtgaccctggtatcagttatcgttctcggcaggaagttcaggaagtgaggagtaagagt
gaccctatcatgcttcacaaagaaaggatggtgaacagcaaacttgccagtgttgaagaa
ttaaaggaaattgatattgaagtaaggaaagaggttgaggatgctgcccagtttgctaca
tctgatccagagccacctttagaagaattaggctgtcatatctactccaaacatccacct
tttgatgttcgtggtgtgaatcaatggataaagtacaaatctgtaagctaa
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