Phascolarctos cinereus (koala): 110208557 Help Entry 110208557         CDS       T05867                                  Symbol SYNE1 Name (RefSeq) LOW QUALITY PROTEIN: nesprin-1   KO K19326   nesprin-1 Organism pcw  Phascolarctos cinereus (koala) Pathway pcw04820   Cytoskeleton in muscle cells Brite KEGG Orthology (KO) [BR:pcw00001]  09140 Cellular Processes   09142 Cell motility    04820 Cytoskeleton in muscle cells     110208557 (SYNE1)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03036 Chromosome and associated proteins [BR:pcw03036]     110208557 (SYNE1) Chromosome and associated proteins [BR:pcw03036]  Eukaryotic type   Centrosome formation proteins    LINC complex     110208557 (SYNE1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Spectrin Spectrin_SYNE1 SYNE1 CH KASH STIV_B116-like Coatomer_g_Cpla CSN7a_helixI Motif Other DBs NCBI-GeneID:  110208557 NCBI-ProteinID:  XP_020842279 UniProt:  A0A6P5KB87 LinkDB All DBs Position Unknown AA seq 8809 aa AA seqDB search MATSSRMLSRSPRDIANVMQRLQDEQEIVQKRTFTKWINSHLAKRNPPMVVDDLFEDMKD GIKLLALLEVLSGQKLPCEQGRHMKRIHSVANIGTALKFLEGRRSMYRGSPIKLVNINST DIADGRPSIVLGLVWTIILYFQIEELTSNLPQLQSLSSSTSSMDSILSSETASPPNKRKV VTKAQGNAKKALLKWVQYTAAKQVGIEVKDFGRSWRSGVAFHSVIHAIRPELVDLEKVKG RPNRENLEEAFTIAETELGIPRLLDPEDVDVDKPDEKSIMTYVAQFLKYYPDVHNTGTDE QENDREDKLVPRETKVWIEQFERDMTRAQMTEASLQDKYQSFKHFRVQYEMKRKQIELLI QPQRRDGKLSLDQALVKQAWDRVSSRLFDWHIQLDKSLPAPLGTIGAWLYRAEVALQEEI TIQQVHEETANTIHRKLEQHKDLLKNIDGHRKAFHEIHRTRSVNGVPVPPEQLEDMAERF NFVSSASELHLMKMEFLELKYRLLSLLVLAESKLKSWIIKYGRRETVELLLQNYISFIEN SKFFEQYEVTYHILKEAAEMYVKADGSVEEAENVMKFMNETTAQWRNLSVEVRSVRSMLE EVISNWDRYSNTVASLQAWLEDAEKMLNQSEHAKKDFFRNLPHWIQQHTTMNDAGNFLIE TCDETVSRDLKQQLLLLNGRWRELFMEVKQYARADELDRMKKEYLDYVTTLSVFTAEANG KLSEPLDVSFLNVKMLFQDLEDIKQKMPGMEAQYKIITRTAQLITKESPQEEAREILATI SGLKDQLNKVKECYPALLYETQQLLIPLEELEKQITLFYEALERINETMSLLEREAQATT LFKQKHQELLSHQESCRKTLTLIEKDSQNVQKFVALSKVLKHFDQSMLQRKVAEVHVAFQ NMVKKTGEWKKHVETNSRLMKKFEESRAELEKVLQIAQASIKEKGDPEALLKKHTEFFSQ LDQRVLNAFLKACDELTDILPEQEQQGLQEAVRKLHKQWKDLQGEAPYHLLHLKIDVEKN RFLASVEECKSELGRENKLVLQEGSEKIIQEHKIFFSDKGPHHLCEKRLQLIEELSLKLP VRDPVRNTPENCQATLRDLKAMIDSTYKKLMENPDKWRDYKTRFSELSSWISAKERELQL MKQEAKDTATYGKSKLAAEEIRDEMNKQGENLGWLKARLKTLTEVSAEKEIQKQDDELTK LSSDFKGLITLLSEVEKMLSTLGDRVQYKEIAKSSLEQLINTSKEVQEQAEKILDTENLI EAQQLLLHHQQKTKRIHAKKKDVQEQIARAKQDEGGLPSRVQEDLKKLEDTLENMEQNRE KQERRLQVTIRKWERFETNKETVVRYLFQTGSSHERFLSFSSLESLSSELDQTKAFSKHT EAIAVQAENLVKEASEIQLGSKTKQTLQQQAKSVKEQVKKLEDTLEEDIKTMEMVKNKWE HFGNNFEALSVWITEREKELDALETSSSPWDMQISQIKVILKRIENNQSDIPRLEEETQS FAQFITTGESARIKAKLTQIRRRWEELKEHAHCLEATLLENESQQQKFEESLKKVQQSVF EFENKLNEPVKVCSSATETYRALQEHMDLCQSLETMSSAVTSLSVSAHKVINKDSSVQEA MTLQQRHEKMISITKEQQMMLENLLAHWQRLEKELSTFLTWLERCEAGATSPESGISADR GKLESELQLVQALQNEVVSHASLYSNLLQLKESLFSVASKDDVKVIQLQLEQLDERWRVL PQIISKRISFLQSVVTEHQQFDELLLSFSVWIKQFLSDLHCTSEISIMDHQAALVQHKDH SAEVESKKEEILQLKAHLGKLCSFSRGEDHHTLQGRAEDCFQLFQEASQMIERRKLALTE LTQFLQAHASLSSVLHRLRQTVEATSNMDKTQSELLEKDLNDAIMDAKNLDCTAINLDGI LTKAQYHLKSGSXEQRASCRKMADQLGLELESIQNLLGTKQSEAEAFEALRKAFVDHKEA LLKSLEDIEERADKERLKELTQQAVQQRLRVFNQLEDELNSHEHELWWLKDKAKQIAQKD VTSAPEFDEEINRLEATWDDTKKLIHENQGQCCGLIDLMREYQNLKSVVYKVLENASNVT MTRSTVKDQEDIRWALSKHETVKTEMNGKQKELDDFTSKGKHLISELKRTQSSDFILVKT DMDSTVDRWLDISEKIEENMDRLTISLSLWEDVLAARDEIDGWSNSSIPQLTENISNLSS SLKTEAFLKEFECEVKNKGLKLEELHSKILNLKGLTKNQETPPDLQFIEKDLRQKLEHAK EVTEIAKGTLKDFTAQKMQLEKFIHEVETWLTKTEESLLNCAQTQNCESLKKVKEIQKEL QGQQSSINSTQENLNSLCRKYHSAELETLGSTITLLIKKHEAVSHLGSRTQASLQDFLEK HFTESMQAFQTWFSGVKAAVRESSDRSGDSKVIEAKLQNLQSILDSISDGQNKLDAVTQE GQNLYAYLSKQIVSSIEEQITKANEEFQAFLKDCLKNKQALQDCATELGSFEDQHKKLSL WIHEMEERLSTENFGEYKQHIPEKKNEVHKVEMFLGELLAARESLDKLSQRGQNLSEEGH GVGKEVRLAAQLLTGYQNLLKITKEKLRTCQVALQEHQALEEALQGMWSWVKDVQDKLAS AESTVGSKAILEKRLLQIQEILLMKGEGEVKLNMAIGKGEQALKSSNKEGQKVIQTQLHT LTDVWDNVMITAVRAQSSLESVITLWNDYMERKVQLEQWMESVDHKVEHPLQPQMGLKEK FSLLDHFQSIVSEADDHVGAFHHVIEKSIELYEKTEDDSLNEASQEELRTQFNDLSTVAK EKMRKVEEIVKDHLMYMDAVHEFTDWLHSAKEELHRWSDASGDSSATQKKLSKIKELIDS RQIGASRLNRVELLAPAVKQSTAASGCELMDTEMQALRSDWKQWEDSVFQTQDCLENLIS QMALSEQEFTAQVAQLEQALEHFTTLLETWSQKIALLEGKNTDQEIVDCWHQEKEILDAL GKAEPLTDELKSQLNDLCRFSRDLSTYSGKVSGLIKEYNSLCLQVSKDCQNKEQILQQRF QKAFRDFQQWLVNAKITTAKCFEVPQNITEVSTSLQKIQEFLSESENGQHKLNMVISKGE LLNPLITKEKAKSVHDKVVTAKEDWKGFYSNLCQKESALENLKIQMKDFEVSAEPVQNWL NKTEKMVRESSSRLHDLPAKRREQQKLQSVLEEINCHEPQLTRLKEKAQQLWGEQAASKN FTHRVSQLSSQYLALSNLTKEKVSRLDRIVAEHNQFSLSVKELQDWMADAVHMLESYCQP TSDKSVLDSRMLKLEALLSVKQEKEIQMKMILTRGECVLQNTSPEGVPAIQQQLQTVKDM WSSLLSTAIRCKSQLEGALSKWTSYQDDVRQFSNWMDNVEASINECERQWAELRDKTMAL GKAKLLNEEVLSHSSLLETIEVKGAGMTEHYVTQLERQDLQERYKAIEDRTKEAVAKCER LVRLHQEYQRDLKAFELWLQREQEKLDHFSLLEGDAKTHETTLHDLQELQIHCAEGQALL NAVLHTREEVIPWGIPQAEDRVLESLRQDWQTYQQKLSETRTQINNIVNKLRLMEQKFQQ VDDWLKTLEEKVNVSTGRQSNRAVKEMQLHQMKKWHEEIATYKDEVEEVGSRAQEILEET QVSSRTGYQATQLTSRYQALLLHVLEQIKFLEEEIQSLDESDLSFSAYTDWYGSTHKNFK NIATETNKVDKIMMQKKMKTLESLLNEVEKGHSLLKSAREKGEKAIQYLEGSEAEILRKE ISGHVERLEELASTVRKEHRTLEKCLQLAKEFTDKYKVQSQWIAEYQAVLHSPEDPKMEL YEKKAQLSKFKSIQQMVLSHEPSVKSINEKGEALLELVPDVTLKDKIQKLQTDYQDLCNA GKEHVMSLEVKVKEHEEYNNELQEVEKWLLQMSGRLVTPDLMEMSSLETITQQLASHKAM MEEIAGFEDRLNDLKTKGDHLISHCADQLQAKLKQNVQAHLQGTKDSYSAICSTAQRVYQ SLEHELQKYVSRQDTLQQCQAWLGAVQPDLKPSPHPPLSRAETVKQVKHFRALQEQARTY LDLLCSMCDLSNSSVKTTAKDIQQTKQTIEQKITNSQSLTQGWEEIKQMKAELWIYFQDA DQQLQNMKRRQAELELNIAQNMVSQVKEFVKKLQSKQAAITAVTEKVNKLTQGQESPEHK EINHLSNQWIDLCLQTNNLHLQREEDLQRTRDYHDRMNVVEVFLEKFTKEWDKLARSDAE STTVHLESLKKLTLALKEKKHIIEDLKDQKQKMIDHLNLDDKELVKEQTSHFEQRWFQLE DLVKRKIQLSVTTLEELNLVQSRFQELTEWAEEQQPGIVEALKQSPPPDLAQNLLMDHLA ICSELESKQMILKSLIKDADRVMVDLGLNERQLIQKVLSDAQCHVSCLSDLVGQRRKHLN KALSEKTQFFMAVFQASSQIQQHERKIMFHEHICLLPDDVSKQVKTCKSAQASLRTYQHE VTGLWAQGRDLMKEATDQEKNEVLSKLQELQGIYDTALQKCSQRLQELEKNLVSRKHFKE DFDKTCHWLKQADIITFPEINLMSFNLHGQLAKYQCLLEQSLEFENLLLTLQRTGQAILP SLNEMDHSYLDEKLNSLPQQFNVVVALAKDKFYKVQEAILARKEYSSLIELTFQSLSELE DQFVNMNKVPTNLSTQEASSLQEACRVLLGEILSLGAAVDELNQKKEGFRSTGQPWQPDE MLKLVTLYHKLKRQTEQRVNLLEDMTNAYQEHEEMCHQLEKQLEAVKKEQTKVNEETLPA EEKLKTYHSLAGSLQDSGILLKRVTGHLEDLSPNVDPMAYGKANQQVKAWQEELTLLTSG ISETVMECENRLVQSIDFQTEICRSLDWLRHVKAQLNGTICLDTKLQNIQEEIRKVQIHQ EEVQSSLRIMNALSSKEKEKFLKAKELISADLENTLAELSELDDEVQEAIRTRQATLTKV YKLCQKYYQVFQAAKDWLEDAQELLQLAGSGLDVEGSEENLRSHVEFFSTENEFRSHLAE LQGLVSKLEPFIKTTGKEELLHKVTSLEEKGKKVIQESQVQLDLLQRCATQWKDYQKSRE DVIELMNEAEKKLSEFSVSKASSSCGAEEKLLDHKSLISLVSSFHERIIALEEKASQLEK NGNDASKATISRSMTTVWQRWTRIRAVAQDQEKILEDAVDEWKSFNSKVQKATEMIDQLQ DNLPGSSAEKASKTELLALLEYHDTFILEVEQQQAALGVLKQQALNMLHDGEVESSTEEE LPITQEITAMQDRCLNMQEKVKTNGKLVKQELKDREVVETKIHSVKSWIQETKEYLVNPT MEIDAQLEELKGLMTEATTHHQAIEKMTEEQKNKYLGLYTILPSELSLQLAEITMNIETI RDQIQAKEKETQRSKAMNQEFSQKIQKTAKELTTILTKLKAKTNDLAQAKIDQKALGEEL DGCNIKLMELDATVQDFTEQNSQLAKQLAKRIGKLTELHQQTIRQAEYRISKLNQATAHL EEYNEMLEFVMKWVEKAKVLVHGNIAWTSASQLRDQFISYQTMLEESGEIHTDLEAMKEK IEYLSSVYCTEGMSQQVSELGRETEGLRQLIRSRLQSLQDAAKDMKKFEAELKILQAALE QAQKTLTSPELGRLSLKEQLSHRQHLLSEMESLKPKAEAVQICQSALRIPEEVVTNLPIC HMALRLQEEASRLQHTAIQQCNIMQEAVVQYEQYEQEMKHLQQLIEGAHREIQDKPVATS NIQELQAQISRHEELAQKIKGYQEQIASLNSKCKMLTMKAKHATMLLTVTEVEALSEGME DLDTELLPTHPTHPSVVMMTAGRCHTLLSPVTEESGEEGTNSEISSPPACRSPSPVANTD ASVNQDIAYYQALSAEQLQNDAARIQASTSSTQEFYDPGLESSTSAKLDDLQRSWETLKN VISEKQRTLYEALERQQKYQDSLQSISTKMEAIEVKLNESLEPSKSPESQMAEHQALMDE ILMLQDEISELQTSLAEGLVSESLEADAAEQLALQSTLIVLAERMSTIKMKASGKRQLLE EKLNEQLEEQRQEQALKRYCCEADELDHWLLSTKATLDSTLVSPTEPMDMEDQLVDCQNM LVEIEQKVVALSELSIHNENLLMEGKAHTKDEAEQLAIKLRTLKGSLLELQRVLHDKQIN IQATSQEKEECEADLTATQSPSVQEWLAQARTTRTQQQQSSLQPQKELEQELAEQKSLLR SVASRGEEILTQHSAGESAGISEKPDEISQELAFEGEKTSAEGHMRMKWESLHQEFSTKQ RLLQNALEQEQEQMLYSRPNRLLPGVPLYKGEGQTQTKSSVTSLLDGLNQAFEEVSSQSG RTGKQNFHLEQKLYDGVSATSTWLDDVEEHLFVATALLPEETETCLYNQETLAKDIKEMS EEMDKNKNLFSQAFPENGDNRDVIEDTLGCLLGRLSLLDSVVNQRCHQMKERLQQILNFQ NDLKLLLTSLADNKYIILQQLASVVEKPAAEQIEAIQQAEDGLKELDASIIELKRRGDKL LIDQPSVQELSKLQDMYDELMMVIASRRSGLNQNLALKSQYERALQDLADLLETGQEKMA GDQKMIVSSKEEVQQLLDKHKEYFQGLESHMILTETLSRKIISLAIPKENQVHMELMAQA STVLKQAHKRGVELEYILETWSHLEDDFQELTRQLEAVENSIPSVGLVEESEERLNDRIT LYQRLKSSLSEYQPKLYQVLDDGKRLLISISCSDLESQLNHLGEHWLNNTSKVTKELHRL ETILKHWTRYQSESADLIHWLQSAKDRLEFWNQQSVTVPQELEMVRDHLNSFLEFSKEVE AKSSQKSSVLATGNQLLRLKKVDTAALRSGLSQIDNQWTELLAHIPVVQEKLHQLQMDKL PSRHAITEVMSWISLMESVIQEDEEKIKNSVGHKAINEYLQKYKGFKIDINCKQLTVDFV NQSVLQITSQDVESKRSDKTDFAEQLGTMNRHWQILQSLVTEKIQMLEGLLESWTEFENN VQCLKIWFETQEKKLKQQHQIGDQASVQNAMKDCQELEDLIKAKEKEIEKVEQSGLSLIK NKKDVSGVIMSNLQELNHYWANLDHRVGQLKILLQSVFDQWNMYKVAYEEMNSYLMEARY SLSRFRLLTGSLEAVKVQVENLQSLQDDLEKQESSLQKFGSITNQLLKECHPPVTETLTN TLKEVNMRWNNLLEEIAEQLHSSKALFQLWQRYKDYSKQCASTIQQQEDRTNELLKAANN KDIVDDEVATWIQDCNDLLKGQKTVQDSLFVLQELGEQLKQQVDTSAAAAIQSDQLSLSQ HLSALEQALSRQQKLLQAGVLDYETFSKSLEGLEGWILEAEEVLRGQDPNHSSDLSTIQD RMEELKGQMLKFSSMAPDLDRLNELGYRLPLNDKEIKRMQNLNRHWSLISSQTTERFSKL QSFLLQHQTFLEKCETWMEFLVQTEQKLAVEISGNYQRLLEQQRAHELFQAEMFSRQQIL HSIIIDGQRLLEQGQVDDRDEFNLKLTLLSNQWQGVIRRAQQRRGIIDSQIRQWQRYREM SEKLRKWLVEVSYQPVSGLGSVPMSLQQARTLFDEVQVKEKVLLRQQGSYIVTVEAGKQL LLSADSGAEAALQAELMEIQERWKSASICLEEQKKKLDFLLKDWEKCEKGIADSLEKLKA FKKKLTQPLPDHHDELHAEQMRCKELENAVGGWTDDLAHLVLLKDTLSAYINADDISILN ERIELLQRQWEELCHQVSLRQQQVNERLNEWAIFSEKNKELCEWLTQMESKVSQNGDILI EEMIEKLKKDYQEEIAVAEENKIQLQQMGERLAKASHESKASDIEYKLGKVNDRWQHLLD LIAARVKKLKETLVAVQQLDKNMSSLRSWLAHIESELAKPIVYDSCDSEEIQKKLNEQQE LQRDIEKHSTGVASVLNLCEVLLHDCDACATETECDSIQQATRNLDRRWRNICAMSMERR LKIEETWRLWQKFLDDYSRFEDWLKLSEKTAAFPSSSGVLYTVAKEELKKFEAFQRQVHE SLTQLELINKQYRRLARENRTDSACSLKQMVHEGNQRWDNLQKRVTSILRRLKHFIGQRE EFETARDSILVWLTEMDLQLTNIEHFSECDVQAKIKQLRAFQQEISLNHHKIEQIIAQGE QLIEKSEPLDAAVIEEELDELRRYCQEVFGRVERYHKKLIRLPLTDDEHDLSDRELDLDE SADLSDIHWHDKSADSVLSPHPFSNLSLSLPQPLRSERSGRDTPASVDSIPLEWDHDYDL SRDLESAVSRTLISEDEEGQEDKDFYLRGAIGLADVVIPESPEAYVKLTENAIRNTSGEP GALESHIRQLDKALDASRFQMQQTENIIRSKTPTGPELDATYKGYMKLLGECSGSIDSVR RLGRKLKEEEEKLSGFINLNSTETQTSGVIDRWELIQAQALSKELRMKQHLQQWQQFNSD LSSIWAWLGETEEELEQLQRLDLSTDIQTIELRIKKLKELQKAVDHRKAIILSINLCSSE FTQSDSEESKELQERLAQMNMRWDRVCSLLEDWRSLLQDALMQCQDFHEMSHGLLLWLEN IDRRKNEIVPINPNLDSEVLQDQHKMLMQIRRELLESQLKVASLQDMSCQLLVNAEGKDC XEAKEKVHVIGNRLKLLLKEVSRHIKDLEKILDISSSQLDLSSWSSADELDTSGSVSPVS GRSTPNRQKTPRGKCSLSPPGPSVNNPHSRSVRGGSDSSPSETQPAQSCQAFLLRVLRAA LPLQFLLLLLIGLACLVPMSEEDYSCALSNNFARSFHPMLRYTNGPPPL NT seq 26430 nt NT seq  +upstreamnt  +downstreamnt atggccacttcctcgagaatgctatcaagatctcctcgagacattgccaatgtgatgcaa agactccaagatgagcaagagatagtgcaaaaacggacttttacaaaatggatcaactct catctggctaagcgaaatcccccaatggtggtggatgatctttttgaagacatgaaagat gggattaaactactggccctcctggaagttctatcagggcagaaactgccatgtgagcaa ggacgccacatgaaaagaattcactcggtggcaaacattggtactgcccttaagtttctt gaaggaagaaggtccatgtacagaggatcaccgattaaactagtgaacataaattccact gacattgctgatggccgaccttctattgtccttggcttggtttggaccattattctgtat tttcagattgaagagttgacgagcaaccttccacaactccagtcactgtccagtagtaca tcttctatggacagcatcctcagctcagaaactgccagcccaccaaacaaacggaaggtg gtgaccaaggcccaagggaatgcaaagaaggccctattaaagtgggtgcagtacacagca gcaaagcaggttgggattgaagtaaaagatttcggacgaagttggagaagtggtgtggca tttcattcagttattcatgctattcggccagaactagtggatttggagaaagtgaaagga agacctaacagggagaacttggaagaggctttcaccattgctgaaacagaattaggaatc ccaagactcctagatcctgaagatgtggatgtggacaaaccagatgagaagtctattatg acttatgtagcccaatttctgaaatattatcctgatgttcataacacaggcactgatgaa caagaaaatgatagggaagacaaactagtgccaagagaaacaaaagtttggatagaacag tttgaaagagatatgacaagggcacaaatgactgaagcgagtttacaggacaaataccag tcatttaagcacttcagagttcagtatgaaatgaagaggaaacaaattgaacttttaatt caaccacaacgcagagatggcaaattgtcacttgatcaagctctggtgaagcaggcatgg gacagagtgtcctctaggctctttgattggcacatacagcttgataagtctcttcctgca ccactaggcacaataggcgcctggctttatagggcagaagttgccttacaggaggaaata actattcagcaggtccatgaagaaactgcaaacacaatacatcggaagctggaacagcat aaggatctacttaaaaacatagatggccacagaaaggcattccatgagatccaccggacc aggtctgttaatggtgtccctgttccacctgaacagttagaggacatggctgaaaggttt aattttgtttcatctgcctcggaactccacctaatgaaaatggaatttctggaattaaag taccggctgttgtcactgttagtcttagcagagtcgaagttaaaatcatggattatcaaa tatggaagaagggagacagtggagctacttctacagaattacatttcttttatagaaaat agtaaattttttgaacaatatgaagtaacgtaccatatcttgaaggaggccgctgaaatg tatgtgaaagcagatggctcagtggaagaggcagagaatgtgatgaaattcatgaatgaa acaactgctcaatggaggaatttgtctgtggaagtgagaagtgtcaggagcatgctagaa gaagtcatttctaactgggacaggtacagcaatactgtggccagtctacaagcctggctg gaggatgctgaaaaaatgttaaaccaatcagagcatgccaaaaaggattttttccgaaat ttacctcattggatccagcagcacacaactatgaatgatgctggcaattttcttattgaa acatgtgacgagacggtttcccgagaccttaagcagcaattgcttttgttaaatggacgt tggagagaactgtttatggaagtgaaacaatatgctcgagcagatgagcttgaccgaatg aaaaaagaatatctagattatgttaccacattgtccgtttttaccgctgaagccaatgga aaactttctgagcctttagatgtttcttttcttaatgtcaagatgttatttcaagattta gaggatattaagcagaagatgcctgggatggaagctcaatacaagattatcacaaggaca gcacagcttattacaaaagagagtccccaagaagaagcccgcgaaatccttgcaaccata tctggactcaaagatcagctaaacaaggtcaaagaatgttaccctgcattactttatgag actcaacagctgctgattccactggaagaattagaaaagcagatcacactcttttatgag gcacttgagaggatcaatgaaactatgtcactccttgaaagggaagcacaagctaccacc ctttttaaacaaaaacatcaggagttgttatctcatcaagaaagttgcaggaagactttg acactaattgagaaagacagtcaaaatgtgcagaaatttgtggccttgagtaaggtgtta aaacactttgatcagagcatgctgcaaaggaaggttgctgaggttcatgttgcttttcag aatatggtaaagaaaactggtgagtggaaaaagcacgtagaaacaaatagccgtttgatg aagaaatttgaggagtccagagcagaactggagaaagttctccagattgcccaggccagc ataaaagaaaaaggggatcctgaagcacttctgaagaaacatacggagttttttagtcag ctggatcagagggtactaaatgccttcctgaaagcttgtgatgagctaactgacatcctc cctgagcaagaacagcagggtctacaggaagctgttagaaaactccataaacaatggaag gatctccaaggagaagctccctatcacttacttcacttaaagatagacgtggagaaaaac agatttctggcttcagtagaagagtgcaaatcagagcttggtcgagagaacaagttggtg ctacaggaaggcagtgaaaagatcattcaagagcataagattttcttcagcgacaaagga ccccatcatctttgtgagaaaaggttacaactgattgaagagctcagtctgaaacttcca gtccgtgaccctgttaggaatacaccggagaactgtcaagccactctcagagatcttaaa gctatgattgatagcacttataagaaattgatggaaaacccagataaatggagagattac aagactagattttctgaactctcatcttggatatctgcaaaagagagagagttgcaactg atgaagcaggaagccaaagatactgccacatacggaaagtccaaacttgctgcagaggaa attagagatgagatgaacaaacaaggagagaatcttggttggttgaaggctaggctgaaa actcttactgaagtttctgctgagaaagaaatccagaagcaagatgatgaactcacaaaa ctctcgagtgacttcaagggcctcataactttgctgtcagaggttgaaaagatgctaagc actcttggggatcgtgtccagtacaaggaaattgcaaaaagctcccttgaacagttaatt aacacctccaaagaagttcaggagcaagcagaaaagatcttggacactgaaaacttaatt gaagcccagcagttacttctacatcatcagcaaaagaccaagaggattcatgcaaagaag aaagacgtgcaagagcagattgccagggctaagcaggatgaaggtgggctacctagcaga gtccaagaggacctgaaaaagctggaggatactttagagaacatggagcagaatagggaa aagcaggagcgccgcctacaggtcacaataagaaagtgggagcgctttgagacaaacaaa gaaacagtggtcagatacctttttcaaacaggttccagccatgaacgtttcttgagtttt agcagcttagagagcctgtcctcagaactggatcagacaaaggcattttctaagcacaca gaagccattgcagttcaggctgagaatcttgtgaaggaagcgtcagagatacagctggga tcgaagactaagcagactcttcagcaacaggccaagtcagtcaaggaacaagtcaagaaa ttggaagacacccttgaagaagatattaaaaccatggaaatggtgaaaaacaagtgggag cattttggcaataattttgaggccctctccgtctggattactgaaagagaaaaagagttg gatgccttggaaacttcatcatctccttgggacatgcaaatcagccaaattaaggttatt ctcaagagaatagaaaataatcaaagtgacattccaagattagaagaggaaactcaatct 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agactgttgcagaatgctctggagcaggaacaagagcagatgctttatagcaggccgaat agactgctgcctggtgtgccgctgtacaaaggggaaggacagactcaaacaaaatcctca gttacatctttgttggatggtttgaaccaggcttttgaagaagtttcatctcagagtgga aggacagggaagcaaaattttcacttggaacagaaattatatgatggagtttcagctacc tctacttggctagatgatgtggaagaacatttatttgttgctacagcccttttaccagaa gaaacagaaacatgtctctataaccaggaaactcttgccaaagatattaaagagatgtct gaggaaatggacaagaacaagaacttgttttcccaagcatttcctgaaaatggtgataat cgcgatgttattgaagacactttgggctgtcttttggggaggctatccttgttagattct gtagtaaatcagcgatgtcatcagatgaaagaaagactgcagcaaatactaaattttcag aatgatctcaaactgcttttgacatcactagcagataacaaatacatcattctgcaacaa ctggccagtgtggtggagaagcctgcagcagaacaaatagaggcaatacagcaggctgaa gatggtctgaaggaattagatgcaagtatcattgaattaaagagacgtggtgataaactg ctgattgaccagccctctgtgcaagaactctctaaactccaggacatgtatgatgaattg atgatggtcattgcttcccggcgcagtgggctaaatcagaatctagcccttaagagtcag tatgaacgagctctgcaagacctggctgacctcctggaaactggtcaagaaaagatggca ggagatcaaaaaatgattgtatcttccaaagaggaagttcaacagctacttgacaagcac aaggagtattttcagggccttgaatcccatatgatcttaactgaaacactctccaggaag ataatcagtttggccatcccaaaggaaaaccaggtccacatggagttgatggctcaggct tcaactgtactaaagcaggctcacaagagaggtgtagagctggaatacattcttgagacc tggtcccatttggaggatgactttcaagaactcaccagacaattggaagcagttgaaaat agcatcccaagtgttggtttggtggaggagagtgaagaaagattaaatgaccggataacg ctgtaccagcggctgaaatcaagcttgtctgaataccagccaaaattataccaggtactg gatgatgggaaaagactgctaatttccattagctgttcagatttagaaagccagctaaat caccttggagaacattggctgaataataccagcaaggttactaaagaactgcacagattg gagacaatattgaaacactggacaagatatcagagtgaatctgctgacctcattcattgg ttgcagtctgcaaaggacaggctagaattttggaatcagcaatcagtgacagttccacaa gaattagaaatggttcgagatcacctgaattctttcctggaattttctaaagaagttgaa gcaaagtcttcccagaaatcttcagttcttgccacaggaaatcagctccttcgactgaag aaagtggacacagcagcacttcgatctggcctgtcacagattgacaaccagtggacagaa ctgctggcacacattccagtagtacaagaaaagttgcatcagctacaaatggataaatta ccttcacgtcatgctattactgaagtcatgagctggatttctcttatggaaagtgttatc caggaggatgaagagaaaattaaaaattctgtaggacacaaagcaataaatgaataccta cagaaatataagggttttaagattgacataaattgtaaacagttgacagtggattttgtg aatcagtcagtgctacaaatcaccagtcaggatgtggaaagtaaacgtagtgataagaca gattttgctgagcagcttggaacaatgaatagacactggcaaatattgcaaagtctagta actgaaaagatccagatgctggaaggtttattggaatcttggacagaatttgaaaataat gtgcaatgtctaaaaatctggttcgaaacccaagaaaagaaacttaaacaacagcatcaa attggagaccaggcttcagttcagaatgcaatgaaagactgtcaggaactggaagattta attaaagccaaagaaaaagaaatagaaaaagtagaacagagtggactttctttgattaag aacaagaaggatgtttctggtgtcatcatgagtaacctgcaagagctcaaccattactgg gcaaatttagaccacagggttggacagctaaagatactactacagtcagtgtttgatcaa tggaatatgtacaaagtggcttatgaggaaatgaacagttacctaatggaagccaggtac tctctttcccgtttccggttgctgactggctccctggaagctgtcaaagtgcaagtagag aaccttcagagtctacaggatgatctagaaaaacaggagagcagcttgcagaaatttggc tctataaccaaccagctgttaaaagagtgtcatccaccagtgacagaaacacttaccaat accttgaaagaagtaaatatgaggtggaataatttgctagaagaaattgctgagcagtta cactccagtaaggccttgtttcagctgtggcaaagatacaaagattattctaaacagtgt gcttcaacaattcagcagcaggaggatcgaaccaatgagttgctgaaggcagcaaataat aaggatattgttgatgatgaagttgcaacctggattcaagattgcaacgaccttctcaaa ggccagaagactgttcaggattcactgtttgtgctccaagagctgggagagcaactcaag cagcaagtagatacttccgcagcagcagccattcagtctgaccagctgtctctgagtcaa cacttgtctgccctggaacaggctcttagcagacagcagaaactactgcaggctggcgtt ctcgactatgaaacattttctaagagtttagaaggactggaaggctggattttagaagct gaagaagtgctaagaggacaggaccccaatcattcatctgacctctcaacaattcaggac aggatggaagaactgaaaggacagatgttaaaattcagcagcatggctccagatttggat cgtctaaatgaattgggatatagattaccactaaatgataaggaaatcaaaaggatgcag aatctgaatagacactggtctttaatctcctctcagaccacggaaagattcagtaagtta caatcgttccttttgcaacatcaaaccttcttggaaaaatgtgagacatggatggaattc ctggttcagacggaacagaagttggctgtagagatttcaggcaattatcaacgtctttta gagcagcagagggcacatgagttgtttcaagcagagatgttcagtcgtcaacagattttg cattcaatcattattgatgggcagcgcctgctagaacaaggtcaagtggatgacagggat gaattcaacctgaagctgacacttcttagtaaccagtggcagggagtcattcgcagggct cagcagagaagagggatcattgatagtcagattcgacagtggcaacgctaccgggagatg tcagagaagcttcgtaaatggttggttgaagtgtcctatcaacctgtgagtggactggga agtgtccctatgtcattacagcaagctaggacactgtttgatgaagtacaggtcaaagaa aaagttctccttaggcaacaagggagctacattgtgactgtggaggctgggaagcagttg ctgctttctgctgatagtggggcagaggcagccctacaggctgaactcatggaaatccag gagagatggaaatcggctagcatctgccttgaagaacagaagaaaaaacttgactttctg ttgaaagactgggaaaaatgtgaaaaaggaatagctgattccctggagaaattgaaagct ttcaaaaaaaagcttacccaaccattgccagatcaccatgatgagctgcatgcagagcaa atgcgttgcaaggagttagaaaatgctgttggaggctggacagatgacttggcacatctg gtactcctaaaggatactctctcagcatacatcaatgctgatgacatctctatcctcaat gaacgcatagagttgctacaaaggcaatgggaagaactctgtcaccaggtatctttacgt cagcagcaggtaaatgagagattgaatgaatgggctatcttcagtgagaagaacaaagag ctttgtgaatggttaactcaaatggaaagcaaagtttctcaaaatggtgacatcctcatt gaagaaatgatagagaagcttaagaaggattatcaggaggaaattgcagttgctgaagag aacaaaatccaactacagcaaatgggagaacgacttgcaaaagctagccatgaaagcaaa gcatcagacatagagtataagctaggaaaggtcaatgacaggtggcaacatctcttggat ctgatcgcagccagggtgaaaaagctcaaggagaccctggtggctgtgcagcagctggat aagaacatgagcagcctcagatcctggcttgcacacattgaatcagagctagctaagccc atcgtctatgactcctgtgactctgaggagatacaaaagaagcttaatgagcagcaggaa cttcaaagggacatagagaaacacagcactggtgttgcatcagtactgaatctgtgtgag gtacttctccatgactgtgacgcatgtgctactgaaacagaatgtgactccattcagcag gcaacacggaacctagacagacgatggagaaatatctgtgcaatgtctatggaaagaaga ctcaaaattgaagagacctggcgattgtggcagaagtttctggatgactattcacgcttt gaagactggctaaagctttctgagaagactgctgccttccccagctcttctggggtgctg tatacagttgctaaggaagagctcaagaaattcgaggctttccagcgacaagtccatgaa agtcttactcaactggaactcatcaataaacagtatagacgcttggcccgtgagaatcgt actgactctgcttgtagcttgaaacagatggtccatgaaggcaaccaaagatgggacaat ttacaaaagcgtgtcacctccatcttgcgcagactcaagcatttcattggccaacgtgaa gagtttgagacagctcgtgatagcattctggtctggctaacagagatggatctgcagctc acaaacattgaacatttttcagaatgtgatgttcaagccaaaataaaacaactcagggca ttccaacaggaaatttcactgaaccaccataaaattgagcagataattgcccaaggagaa caattgattgaaaagagtgaaccactggatgcagctgtcattgaagaagaactggatgaa ctccgacgttactgtcaggaagtctttggtcgtgtggaacgataccataagaaattgatt cgccttcctctgacagatgatgagcatgacttgtctgacagagagctggacctggatgaa tcggcagatctctctgacatccattggcatgacaagtctgcagacagcgtgctttccccg catccattctccaacctctcactttcactcccccaacctctccgaagtgagaggtcagga cgagatactcctgcaagtgtggactccatccctctagagtgggatcatgactatgacctc agtcgtgacctagaatcagcagtttcaagaactctaatatccgaggacgaagagggtcaa gaagacaaagatttctacctccggggagctattggtttagcagatgtagtgatcccagaa agccctgaggcctatgtaaaactcacagaaaatgcaatcagaaatacctctggtgagcca ggagccttagaatcacatatccgacagcttgataaagccctagatgccagccgttttcag atgcagcaaacagaaaatatcatccgtagcaaaacacccaccggacctgaattagatgct acttataaaggatatatgaaattgctgggtgagtgcagcgggagcattgattcagtgagg agattggggcgcaagctgaaagaagaagaggagaagttatctgggttcattaacctgaat agcacagaaacacaaacatcgggtgtgattgatcgatgggagctgatccaggcccaggcc ctgagcaaggagctgcgaatgaagcaacatctccagcagtggcagcagttcaactctgac ctgagcagcatctgggcgtggctgggggagacggaagaggagctagagcagcttcagcgt ctggatctcagcactgacattcagaccatcgagctccgaatcaaaaaactaaaggagctt cagaaagcagttgatcaccgcaaagccatcatcctttccataaatttgtgcagctcagaa ttcacacagtctgatagtgaggagagcaaggagctccaagagcgattggcccaaatgaat atgcgctgggaccgagtgtgcagtttgctagaagactggcgtagcttactgcaggatgcc ttaatgcaatgtcaggatttccatgaaatgagccatggattgcttctgtggttggagaac attgacaggagaaaaaatgaaatagttcctattaatccaaaccttgactcagaagtactt caggaccaacacaagatgcttatgcaaatcagacgcgagttgctggagtctcaactaaag gtggcatcactgcaagatatgtcctgccaactcttagttaatgctgaaggaaaagactgt ntggaagccaaagaaaaagtccatgtcattggaaatcgacttaaacttctcttgaaagag gttagtcgtcatatcaaggacctcgagaagatcttagatatatcaagcagtcaactggat ttatcctcttggtcttctgctgatgaactggacacctcgggatctgtgagtcctgtgtca ggaagaagcaccccaaacagacagaaaacgccacggggcaaatgtagtctctcaccgcct ggaccctctgtcaacaatccacatagcaggtccgtaagaggtggctccgattcctcccct tctgagacccagccagctcagtcctgccaggccttcctcctccgagtcctcagagccgct ttacctcttcagtttctccttttgctcttaattggtcttgcctgcctggtaccaatgtct gaggaggactacagctgtgccctctccaataattttgcccgatcattccaccccatgctc agatataccaatggcccacctcctctatga

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